pathogenicity
clinvar-pathogenicity-prediction-dataset
ClinVar Protein Variant Pathogenicity Prediction Dataset
This dataset contains the final processed modeling table used in the
ClinVar-Pathogenicity-Prediction project. It is derived from the ClinVar
variant summary and the UniProt human reference proteome, and is intended for
machine-learning experiments on protein variant pathogenicity prediction.
Dataset Files
data/train.parquet: 80% stratified training split with 5,009,581 rows.
data/test.parquet: 20% stratified test… See the full description on the dataset page: https://huggingface.co/datasets/Rain021217/clinvar-pathogenicity-prediction-dataset.protein_structure_pathogenicity_dataset
Protein Structure Pathogenicity Dataset
Dataset Description
This dataset contains protein structures and metadata for benign and pathogenic missense variants, designed for training machine learning models to predict variant pathogenicity using protein structural information.
Dataset Summary
The dataset includes:
Protein 3D structures predicted via ESMFold
Benign and pathogenic variants derived from the ProteinGym benchmark
Structural and sequence… See the full description on the dataset page: https://huggingface.co/datasets/CHGGM-Aachen/protein_structure_pathogenicity_dataset.pathogenicity_scores.tar.gz