openfold3
SNAP25_ESM2_OpenFold3_Structural_Analysis
🧬 SNAP25 OpenFold3 Structural Analysis Dataset
Comprehensive structural predictions and therapeutic discovery data for 677 SNAP25 missense variants
🎯 Overview
This dataset provides the first comprehensive structural analysis of SNAP25 (Synaptosomal-Associated Protein 25 kDa) missense variants, generated to support therapeutic discovery for SNAP25-related developmental and epileptic encephalopathy (DEE-SNAP25).
SNAP25 is a critical component of the neuronal… See the full description on the dataset page: https://huggingface.co/datasets/SkyWhal3/SNAP25_ESM2_OpenFold3_Structural_Analysis.openfold3-mcl1-expanse
OpenFold3 MCL1 protein-ligand ensemble (20 predictions) on SDSC Expanse V100
Ensemble of 20 AlphaFold3-equivalent structure predictions for the
MCL1 protein–ligand complex (official OpenFold3 example, PDB 5FDR context),
generated with OpenFold3 0.4.5 on a single NVIDIA V100 32 GB GPU on
SDSC Expanse (gpu-shared partition).
Data
20 predicted structures (PDB): predictions/seed_{42,1337,2024,2026}/mcl1_*_model.pdb
4 seeds × 5 diffusion samples = 20 independent… See the full description on the dataset page: https://huggingface.co/datasets/zonca/openfold3-mcl1-expanse.