SNAP25
Datasets
All datasets matching “SNAP25”SNAP25_ESM2_OpenFold3_Structural_Analysis
🧬 SNAP25 OpenFold3 Structural Analysis Dataset
Comprehensive structural predictions and therapeutic discovery data for 677 SNAP25 missense variants
🎯 Overview
This dataset provides the first comprehensive structural analysis of SNAP25 (Synaptosomal-Associated Protein 25 kDa) missense variants, generated to support therapeutic discovery for SNAP25-related developmental and epileptic encephalopathy (DEE-SNAP25).
SNAP25 is a critical component of the neuronal… See the full description on the dataset page: https://huggingface.co/datasets/SkyWhal3/SNAP25_ESM2_OpenFold3_Structural_Analysis.SNAP25-RAG-Nemotron
🧬⚡ SNAP25-ARIA RAG Database v2.0 - NVIDIA Nemotron Embeddings
The first comprehensive RAG database for SNAP25 therapeutic research.
A pre-built ChromaDB vector database containing:
76,592 indexed text chunks from 2,043 curated PubMed Central (PMC) biomedical papers + 683 OpenFold3 structural analysis reports + 53 expert-curated knowledge entries,
embedded with NVIDIA's state-of-the-art Llama-Nemotron-Embed-1B-v2 model featuring 2048-dimensional embeddings.
🤝 Built for the SNAP25… See the full description on the dataset page: https://huggingface.co/datasets/SkyWhal3/SNAP25-RAG-Nemotron.SNAP25-Eval-Harness
SNAP25 LLM Evaluation Harness
V4 Medical Scoring evaluation harness for SNAP25 domain knowledge.
Adapted from STXBP1 eval harness - same methodology, different gene focus.
Files
File
Description
snap25_benchmark_v1.json
50 questions across 9 categories
snap25_eval.py
Main evaluation script
verify_citations_snap25.py
Citation verification tool
generate_summary_report_snap25.py
Report generator
test_snap25_aria.py
Quick test script for SNAP25-ARIA… See the full description on the dataset page: https://huggingface.co/datasets/SkyWhal3/SNAP25-Eval-Harness.