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pyaging/yingadaptage

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Model Card

yingadaptage

Causality-enriched age predictor restricted to adaptive/protective age-related CpGs, with feature penalties weighted by EWMR causality scores.

Predictsadaptive epigenetic age
SpeciesHomo sapiens
Tissuewhole blood
Data typeDNA methylation
Model typecausality-weighted elastic net regression
Year2024

Use with pyaging

python
import pyaging as pya

pya.pred.predict_age(adata, ["yingadaptage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Ying, K., Liu, H., Tarkhov, A.E. et al. Causality-enriched epigenetic age uncouples damage and adaptation. Nature Aging 4, 231–246 (2024).

https://doi.org/10.1038/s43587-023-00557-0