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pyaging/senchronoage

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Model Card

senchronoage

Senescence-enriched chronological-age predictor restricted to CpGs whose directions were concordant across in-vitro senescence, age and mortality analyses.

Predictschronological age
SpeciesHomo sapiens
Tissuewhole blood
Data typeDNA methylation
Model typeelastic net regression
Year2026

Use with pyaging

python
import pyaging as pya

pya.pred.predict_age(adata, ["senchronoage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Kasamoto, K., Gibson, J., Moqri, M., Smith, R. & Higgins-Chen, A.T. DNA methylation signatures of cellular senescence are not reversed by senolytic treatment. Aging Cell 25, e70430 (2026).

https://doi.org/10.1111/acel.70430