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pyaging/retroelementagev2

sourceHugging Facemitupdated 1mo agoView on Hugging Face
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Model Card

retroelementagev2

Composite Retroelement-Age V2 extends the retroelement annotation to CpGs compatible across EPIC v1.0 and v2.0 and was trained by 10-fold-cross-validated elastic net.

Predictschronological age
SpeciesHomo sapiens
Tissuewhole blood
Data typeDNA methylation
Model typeelastic net regression
Year2024

Use with pyaging

python
import pyaging as pya

pya.pred.predict_age(adata, ["retroelementagev2"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Ndhlovu, Lishomwa C., et al. "Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements." Aging Cell 23 (2024): e14288.

https://doi.org/10.1111/acel.14288