Modelpublic

pyaging/retroelementagev1

sourceHugging Facemitupdated 1mo agoView on Hugging Face

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Model Card

retroelementagev1

Whole-blood Retroelement-Age V1, trained by 10-fold-cross-validated elastic net on EPIC v1.0 CpGs annotated to HERV and active LINE elements.


Predicts	chronological age
Species	Homo sapiens
Tissue	whole blood
Data type	DNA methylation
Model type	elastic net regression
Year	2024

Use with pyaging

python

import pyaging as pya

pya.pred.predict_age(adata, ["retroelementagev1"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Ndhlovu, Lishomwa C., et al. "Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements." Aging Cell 23 (2024): e14288.

https://doi.org/10.1111/acel.14288