Modelpublic

pyaging/pcgrimage

sourceHugging Facemitupdated 1mo agoView on Hugging Face

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Model Card

pcgrimage

Principal-component proxy trained to reproduce the original DNAm GrimAge score; age and sex are additional model inputs.


Predicts	mortality risk
Species	Homo sapiens
Tissue	whole blood
Data type	DNA methylation
Model type	PCA + elastic net regression
Year	2022

Use with pyaging

python

import pyaging as pya

pya.pred.predict_age(adata, ["pcgrimage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Higgins-Chen, Albert T., et al. "A computational solution for bolstering reliability of epigenetic clocks: implications for clinical trials and longitudinal tracking." Nature Aging 2 (2022): 644–661.

https://doi.org/10.1038/s43587-022-00248-2