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pyaging/cellpopage

sourceHugging Facemitupdated 1mo agoView on Hugging Face
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Model Card

cellpopage

CellPopAge is an elastic-net DNA-methylation clock using 42 selected CpGs to predict passage-based age of serially cultured adult primary human fibroblast populations and screen compounds that decelerate this measure.

Predictscell-population passage age
SpeciesHomo sapiens
Tissuecultured fibroblasts
Data typeDNA methylation
Model typeelastic net regression
Year2024

Use with pyaging

python
import pyaging as pya

pya.pred.predict_age(adata, ["cellpopage"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Lujan, Celia, et al. "An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo." Genome Medicine 16 (2024): 85.

https://doi.org/10.1186/s13073-024-01349-w