datasets
Training and evaluation data, with the modality, task and licence stated up front. Listed live from the Hugging Face Hub.
protein_stability_single_mutation
Protein Data Stability - Single Mutation
This repository contains data on the change in protein stability with a single mutation.
Attribution of Data Sources
Primary Source: Tsuboyama, K., Dauparas, J., Chen, J. et al. Mega-scale experimental analysis of protein folding stability in biology and design. Nature 620, 434–444 (2023). Link to the paper
Dataset Link: Zenodo Record
As to where the dataset comes from in this broader work, the relevant dataset (#3) is shown in… See the full description on the dataset page: https://huggingface.co/datasets/Trelis/protein_stability_single_mutation.africa-synth-population-ovarian-somatic-mutations-somalia
Africa Synth Population Ovarian Somatic Mutations Somalia | Africa (Electric Sheep Africa metadata inventory)
Size category: 10K<n<100K - Formats: parquet - Sector: health - Engineered by Electric Sheep Africa
TL;DR
This dataset is part of the Electric Sheep Africa catalog on Hugging Face. It is indexed for African data discovery with standardized metadata, loading guidance, provenance notes, and analyst-oriented context.
What This Dataset Covers… See the full description on the dataset page: https://huggingface.co/datasets/electricsheepafrica/africa-synth-population-ovarian-somatic-mutations-somalia.protein-mutation-stability-instability-v0.1
protein-mutation-stability-instability-v0.1
What this dataset does
This dataset evaluates whether models can detect protein instability caused by mutation effects.
Each row represents a simplified mutation scenario described through structural and interaction proxies.
The task is to determine whether the mutation is likely to destabilize the protein.
Core stability idea
Mutation instability does not depend on mutation severity alone.
A mutation may be tolerated… See the full description on the dataset page: https://huggingface.co/datasets/ClarusC64/protein-mutation-stability-instability-v0.1.ABX-RM-014_dna_gyrase_mutation_cascade-v0.1ABX-RM-014 DNA Gyrase Mutation Cascade
Purpose
Detect staged gyrA then parC mutation accumulation under fluoroquinolone stress before MIC crosses a resistant cutoff.
Core pattern
stress_index high
gyrA_mut_frac rises first
parC_mut_frac follows
MIC stays below resistant_mic_cutoff_mg_L during early cascade
later MIC crosses resistant_mic_cutoff_mg_L
Files
data/train.csv
data/test.csv
scorer.py
Schema
Each row is one timepoint in a within strain series.
Required columns
row_id
series_id… See the full description on the dataset page: https://huggingface.co/datasets/ClarusC64/ABX-RM-014_dna_gyrase_mutation_cascade-v0.1.splunk_mutation_50kDRD2-mutationsAll possible mutations to a specific coding sequence of the human DRD2 gene, classified as missense or synonymous, PTVs are classed as missense.
Dataset can be used as a 1st pass evaluation of DNA language models, which should assign higher likelihoods/probabilities to synonymous mutations then to missense mutations.
leetcode-contests-431-467-mutations-cleanleetcode-contests-431-467-mutations-strat110