metaXu264/inverse-folding-cas13

Inverse-Folding Cas13 reproduction assets

This dataset repository transports the small, versioned data/raw/ and data/processed/ assets required to reproduce the computational DjCas13d research workflow in `XuJP264/Inverse-Folding-Cas13`.

It contains deposited structural records, their source metadata and SHA256 receipts, a bounded NCBI RefSeq Cas13d snapshot, cited literature artifacts, and the derived bound evolutionary prior. Per-file source and usage information is stored beside each raw asset and in the Git repository's source manifests. NCBI records retain the submitter-rights caveat recorded by the project. PDB records remain subject to the RCSB PDB data-use terms. Literature files retain their source-specific terms. The license: other label reflects this mixed provenance; it is not a blanket relicensing of upstream material.

No model weights are included. Frozen ProteinMPNN, LigandMPNN, and ESM-IF1 checkpoints must be fetched from the official URLs and verified against configs/h100_model_assets.json. Generated candidates and large evaluation outputs are also excluded.

All candidate-related uses remain computational research only. These assets do not establish Cas13 activity, cleavage, specificity, safety, expression, stability, therapeutic utility, wet-lab approval, or experimental validation.