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marin-dna/genomes-v5-validation-intervals-v15_255_255

bolinas-dna/genomes-v5-validation-intervals-v15_255_255 Conservation-encoded human validation probe for the v15 (downstream-of-CDS) region recipe, matched to the bolinas-dna/genomes-v5-genome_set-*-intervals-v15_255_128 training sets. Produced by the snakemake/training_dataset pipeline (commit 8db58254831f). Size 16,384 sequences in validation.parquet (a subsample of up to 16,384 human windows). Exact row count — HuggingFace's auto-generated count can be wrong.… See the full description on the dataset page: https://huggingface.co/datasets/marin-dna/genomes-v5-validation-intervals-v15_255_255.

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bolinas-dna/genomes-v5-validation-intervals-v15_255_255

Conservation-encoded human validation probe for the v15 (downstream-of-CDS) region recipe, matched to the bolinas-dna/genomes-v5-genome_set-*-intervals-v15_255_128 training sets. Produced by the `snakemake/training_dataset` pipeline (commit `8db58254831f`).

Size

16,384 sequences in validation.parquet (a subsample of up to 16,384 human windows). Exact row count — HuggingFace's auto-generated count can be wrong.

Region recipe: v15

The 256 bp immediately downstream (3′) of each CDS (get_downstream_of_CDS(dist=256)), clipped to defined. A proximal-3′ / terminator-adjacent counterpart to the upstream promoter recipe (v1).

Built on the human genome (GRCh38 / GCF_000001405.40).

Schema

A single validation.parquet. Each row:

FieldTypeDescription
idstr{chrom}:{start}-{end} — 0-based half-open, bare RefSeq chrom names.
seqstr255 bp DNA with conservation-encoded case (see below).

Sequence case = phyloP conservation

Each base's case is overwritten to encode conservation (the source soft-masking is discarded):

  • —Uppercase — phyloP-241way (Cactus 241-way alignment) score ≥ 2.27 at this position (conserved).
  • —Lowercase — score < 2.27, or there is no alignment / the score is missing (NaN, which compares false). Non-conserved and unaligned bases are not distinguished.
⚠️ This is the opposite convention to the training sets, where lowercase means repeat-masked, not non-conserved.

Construction

  1. 1.Build the v15 interval set on the human genome and tile into 255 bp / 255 bp (non-overlapping) windows.
  2. 2.Subsample up to 16384 windows (seed 42).
  3. 3.Re-encode each base's case by phyloP-241way ≥ 2.27.

Provenance