jablonkagroup/pampa_ncats
Dataset Details Dataset Description PAMPA (parallel artificial membrane permeability assay) is a commonly employed assay to evaluate drug permeability across the cellular membrane. PAMPA is a non-cell-based, low-cost and high-throughput alternative to cellular models. Although PAMPA does not model active and efflux transporters, it still provides permeability values that are useful for absorption prediction because the majority of drugs are absorbed by passive… See the full description on the dataset page: https://huggingface.co/datasets/jablonkagroup/pampa_ncats.
Dataset Details
Dataset Description
PAMPA (parallel artificial membrane permeability assay) is a commonly employed assay to evaluate drug permeability across the cellular membrane. PAMPA is a non-cell-based, low-cost and high-throughput alternative to cellular models. Although PAMPA does not model active and efflux transporters, it still provides permeability values that are useful for absorption prediction because the majority of drugs are absorbed by passive diffusion through the membrane.
- Curated by:
- License: CC BY 4.0
Dataset Sources
Citation
<!-- If there is a paper or blog post introducing the dataset, the APA and Bibtex information for that should go in this section. -->
BibTeX:
@article{siramshetty2021validating,
title={Validating ADME QSAR Models Using Marketed Drugs},
author={Siramshetty, Vishal and Williams, Jordan and Nguyen, DHac-Trung and Neyra, Jorge and Southall,
Noel and Math'e, Ewy and Xu, Xin and Shah, Pranav},
journal={SLAS DISCOVERY: Advancing the Science of Drug Discovery},
volume={26},
number={10},
pages={1326--1336},
year={2021},
publisher={SAGE Publications Sage CA: Los Angeles, CA}
}