RationAI/PanNuke
PanNuke Description PanNuke is a semi-automatically generated dataset for nuclei instance segmentation and classification, providing comprehensive nuclei annotations across 19 tissue types and 5 distinct cell categories. The dataset includes a total of 189,744 labeled nuclei, each accompanied by an instance segmentation mask, and contains 7,901 images, each sized 256×256 pixels. The images were captured at x40 magnification with a resolution of 0.25 µm/pixel. The… See the full description on the dataset page: https://huggingface.co/datasets/RationAI/PanNuke.
PanNuke

Dataset Description
- Homepage: PanNuke Dataset for Nuclei Instance Segmentation and Classification
- Leaderboard: Panoptic Segmentation
Description
PanNuke is a semi-automatically generated dataset for nuclei instance segmentation and classification, providing comprehensive nuclei annotations across 19 tissue types and 5 distinct cell categories. The dataset includes a total of 189,744 labeled nuclei, each accompanied by an instance segmentation mask, and contains 7,901 images, each sized 256×256 pixels. The images were captured at x40 magnification with a resolution of 0.25 µm/pixel. The dataset is highly imbalanced, with the "Dead" nuclei category being particularly underrepresented.
Please note that the dataset was created by extracting patches from whole-slide images (WSIs). As a result, some nuclei located at the edges of patches may be cropped, with fewer than 10 visible pixels in certain cases.
Dataset Structure
The dataset is organized into three folds: fold1, fold2, and fold3, consistent with the original dataset structure. Each fold contains data in a tabular format with the following four columns:
- `image`: The RGB tile of the sample.
- `instances`: A list of nuclei instances. Each instance represents exactly one nucleus and is in binary format (
1- nucleus,0- background) - `categories`: An integer class label for each nucleus, corresponding to one of the following categories:
- Neoplastic
- Inflammatory
- Connective
- Dead
- Epithelial
- `tissue`: The integer tissue type from which the sample originates, belonging to one of these categories:
- Adrenal Gland
- Bile Duct
- Bladder
- Breast
- Cervix
- Colon
- Esophagus
- Head & Neck
- Kidney
- Liver
- Lung
- Ovarian
- Pancreatic
- Prostate
- Skin
- Stomach
- Testis
- Thyroid
- Uterus
Citation
@inproceedings{gamper2019pannuke,
title={PanNuke: an open pan-cancer histology dataset for nuclei instance segmentation and classification},
author={Gamper, Jevgenij and Koohbanani, Navid Alemi and Benes, Ksenija and Khuram, Ali and Rajpoot, Nasir},
booktitle={European Congress on Digital Pathology},
pages={11--19},
year={2019},
organization={Springer}
}@article{gamper2020pannuke,
title={PanNuke Dataset Extension, Insights and Baselines},
author={Gamper, Jevgenij and Koohbanani, Navid Alemi and Graham, Simon and Jahanifar, Mostafa and Khurram, Syed Ali and Azam, Ayesha and Hewitt, Katherine and Rajpoot, Nasir},
journal={arXiv preprint arXiv:2003.10778},
year={2020}
}