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ClarusC64/ABX-RM-001_esbl_hyperproduction_spike-v0.1

ABX-RM-001 ESBL Hyperproduction Spike Purpose Detect a surge in beta lactamase activity that occurs before the ceftriaxone MIC shifts into a clear resistant range. Core pattern beta_lactamase_activity_rel rises sharply mic_ceftriaxone_mg_L stays near baseline at the spike moment mic_ceftriaxone_mg_L rises later Files data/train.csv data/test.csv scorer.py Schema Each row is one timepoint in a within strain series. Required columns row_id series_id timepoint_h organism strain_id… See the full description on the dataset page: https://huggingface.co/datasets/ClarusC64/ABX-RM-001_esbl_hyperproduction_spike-v0.1.

sourceHugging Facemitupdated 8mo agoView on Hugging Face
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Dataset Card

ABX-RM-001 ESBL Hyperproduction Spike

Purpose

Detect a surge in beta lactamase activity that occurs before the ceftriaxone MIC shifts into a clear resistant range.

Core pattern

  • —betalactamaseactivity_rel rises sharply
  • —micceftriaxonemg_L stays near baseline at the spike moment
  • —micceftriaxonemg_L rises later

Files

  • —data/train.csv
  • —data/test.csv
  • —scorer.py

Schema

Each row is one timepoint in a within strain series.

Required columns

  • —row_id
  • —series_id
  • —timepoint_h
  • —organism
  • —strain_id
  • —blagenefamily
  • —blacopynumber_rel
  • —betalactamaseactivity_rel
  • —micceftriaxonemg_L
  • —micmeropenemmg_L
  • —media
  • —assay_method
  • —source_type
  • —hyperproduction_signal
  • —earliest_hyperproduction

Labels

  • —hyperproduction_signal
  • —1 for rows at or after the first confirmed hyperproduction spike
  • —earliest_hyperproduction
  • —1 only for the first detected spike row in that series

Scorer logic in v1

  • —baseline is timepoint 0
  • —candidate spike
  • —activity fold increase at least 4x vs baseline
  • —MIC fold at spike no more than 2x vs baseline
  • —not a spike and snapback artifact
  • —confirmation
  • —later MIC reaches at least 4x baseline

Evaluation

Run

  • —python scorer.py --path data/test.csv