sdilbaz/prime_py

PRIME - Papillomavirus Rapid Interface for Modelling and Economics

A comprehensive health economic model for evaluating the impact of HPV vaccination programs on cervical cancer burden.

Features

• —Cohort Analysis: Model vaccination impact across birth cohorts
• —Economic Evaluation: Cost-effectiveness analysis with disability-adjusted life years (DALYs)
• —Sensitivity Analysis: Probabilistic sensitivity analysis using Monte Carlo methods
• —Interactive UI: Streamlit-based interface for parameter configuration and results visualization

Model Components

• —HPV transmission dynamics and vaccine efficacy
• —Cervical cancer natural history
• —Healthcare costs and quality-adjusted life years
• —Population demographics and life tables
• —Country-specific epidemiological data

Data Sources

• —GLOBOCAN 2020 cancer incidence and mortality data
• —WHO demographic data
• —Published literature on HPV epidemiology and vaccine efficacy

Usage

The application provides an interactive interface to:

1. 1.Configure vaccination scenarios
2. 2.Set economic parameters
3. 3.Run cohort simulations
4. 4.Visualize health and economic outcomes

License

MIT License