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App README

Bayesian Evidence Synthesis API

Live Space License: AGPL-3.0

A web API for Bayesian evidence synthesis and Meta-Analytic Predictive (MAP) prior generation.

This service provides automated report generation based on Bayesian meta-analysis workflows commonly used in clinical development and historical borrowing applications.

Overview

The API is powered by:

BayesianEvidenceSynthesis.jl

https://github.com/martingramage/BayesianEvidenceSynthesis.jl

and exposes a simplified interface for generating evidence synthesis reports without requiring a local Julia installation.

Features

  • Meta-Analytic Predictive (MAP) prior construction
  • Effective Sample Size (ESS) estimation
  • Robustified prior generation
  • Automated PDF report creation
  • Browser-based access through Hugging Face Spaces

API Endpoint

Generate Report

POST /generate_report

Input

A data file containing the studies to be synthesized.

Output

A PDF report including:

  • MAP posterior distributions
  • ESS diagnostics
  • Robustified priors
  • Summary statistics
  • Graphical outputs

Architecture

text
Client
   │
   ▼
Hugging Face Space
   │
   ▼
Oxygen.jl API
   │
   ▼
BayesianEvidenceSynthesis.jl
   │
   ▼
PDF Report

Source Code

Core Package

https://github.com/martingramage/BayesianEvidenceSynthesis.jl

Methodological Study

https://github.com/martingramage/RBest-vs-Bayesmeta

Intended Use

This API is intended for:

  • Bayesian statisticians
  • Clinical trial researchers
  • Pharmaceutical statisticians
  • Evidence synthesis workflows
  • Historical borrowing studies

Disclaimer

This software is intended for research and methodological evaluation purposes. Users remain responsible for validating all analyses and outputs before use in regulatory, clinical, or decision-making settings.

License

This project is licensed under the GNU Affero General Public License v3.0 (AGPL-3.0).

See the LICENSE file for details.