VanathiRajagopalan/chemo-response-explainable-ai

Chemotherapy Response Explainable AI

Predict chemotherapy drug response and visualize gene-wise SHAP explanations.

Features

• —Predicts drug response for given samples
• —Generates SHAP explanations for feature/gene importance
• —Upload a CSV and get predictions instantly

Input CSV Format

Your CSV file should include these columns:

NLMERESULTID,NLMECURVEID,COSMICIDx,DRUGIDx,COMPANYID,MINCONC,MAXCONC,LNIC50x,AUCx,RMSE,ZSCOREx,COSMICIDy,DRUGIDy,LNIC50y,AUCy,ZSCORE_y

Example Row

342,15723040,908159,1,1045,0.007813,2.0,2.301634,0.986271,0.016214,-0.194054,908159,1199,2.96888,0.950931,-0.8234

Usage

1. 1.Upload your CSV file in the Space.
2. 2.Click Submit.
3. 3.View:
4. 4.Predicted chemotherapy drug response
5. 5.SHAP feature importance plot

Notes

• —Make sure all required columns are present in the CSV.
• —The SHAP plot explains which features/genes contribute most to the prediction.

Check the Hugging Face Spaces configuration reference for more details.