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Aurigene-AI/protein-target-explorer

sourceHugging Facemitupdated 14d agoView on Hugging Face
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🧬 Protein Target Explorer

Type a UniProt accession (P00533), a human gene symbol (EGFR), a PDB ID (1M17) or paste a raw sequence and get:

  • the target's UniProt annotation: function, domains, binding sites, disease variants, keywords,
  • its AlphaFold model in an interactive 3D viewer coloured by per-residue confidence (pLDDT), with surface, sticks and spin modes,
  • every experimental PDB structure cross-referenced in UniProt (sorted by resolution) — click View to load it with bound ligands rendered as sticks,
  • approved and investigational drugs hitting the target (DrugBank), plus quick links to ChEMBL, BindingDB and Open Targets,
  • sequence physicochemistry: molecular weight, isoelectric point, GRAVY, net charge at pH 7.4, aromaticity, aliphatic index, extinction coefficient,
  • amino-acid composition and a Kyte–Doolittle hydropathy profile.

Everything is fetched live from UniProt, AlphaFold DB and RCSB and rendered with 3Dmol.js in your browser. Built by Aurigene AI.