Datasetpublic
phenixace/S2-TOMG-Bench

S^2-Bench Dataset (TOMG) (full version, 45k entries) Official Huggingface Datasets for S^2-Bench: "Speak-to-Structure: Evaluating LLMs in Open-domain Natural Language-Driven Molecule Generation" Please refer to our Github Repo for more usage and useful information. Configurations Each configuration represents a different task: MolCustom_AtomNum: Molecular customized generation by atom number MolCustom_BondNum: Molecular customized generation by bond number… See the full description on the dataset page: https://huggingface.co/datasets/phenixace/S2-TOMG-Bench.
sourceHugging Faceapache-2.0updated 8mo agoView on Hugging Face
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rootMolEdit_DelComponent.csv
MolEdit_DelComponent.csv5002 linesDownload Raw Back to root
1index,Instruction,molecule,removed_group226974,Please remove a benzene_ring from the molecule O=C(Cc1ccc(Cl)cc1)NC[C@](O)(c1ccccc1)C(F)(F)F.,O=C(Cc1ccc(Cl)cc1)NC[C@](O)(c1ccccc1)C(F)(F)F,benzene_ring375570,Please remove a amide from the molecule O=C(C[NH+]1C[C@H]2CC=CC[C@H]2C1)NOCc1ccccc1.,O=C(C[NH+]1C[C@H]2CC=CC[C@H]2C1)NOCc1ccccc1,amide4102138,Please remove a amide from the molecule COC(=O)c1c(C)[nH]c(C(=O)NC2=NCCS2)c1C.,COC(=O)c1c(C)[nH]c(C(=O)NC2=NCCS2)c1C,amide5218964,Please remove a halo from the molecule C[C@H](Oc1ccc([N+](=O)[O-])cc1F)C(=O)[O-].,C[C@H](Oc1ccc([N+](=O)[O-])cc1F)C(=O)[O-],halo654266,Remove a amine from the molecule CCCN/C(N)=[NH+]/CC[C@@H](C)SC.,CCCN/C(N)=[NH+]/CC[C@@H](C)SC,amine7226306,Please remove a halo from the molecule Ic1ncn(C2CCCC2)n1.,Ic1ncn(C2CCCC2)n1,halo8116785,Please remove a benzene_ring from the molecule CC[C@H](C)Oc1ccc(NC(=O)/C=C/C(=O)[O-])cc1.,CC[C@H](C)Oc1ccc(NC(=O)/C=C/C(=O)[O-])cc1,benzene_ring9129774,Please remove a benzene_ring from the molecule C[C@H]1COC[C@H](C)N1C(=O)c1cc(F)c(F)cc1Cl.,C[C@H]1COC[C@H](C)N1C(=O)c1cc(F)c(F)cc1Cl,benzene_ring104647,Remove a halo from the molecule O=C(NCCCc1n[nH]c(=O)[nH]1)[C@H]1C[C@@H]1c1c(F)cccc1F.,O=C(NCCCc1n[nH]c(=O)[nH]1)[C@H]1C[C@@H]1c1c(F)cccc1F,halo11241035,Remove a benzene_ring from the molecule O=C([C@@H](O)c1ccccc1)N1CCN(c2ncc(Cl)cc2Cl)CC1.,O=C([C@@H](O)c1ccccc1)N1CCN(c2ncc(Cl)cc2Cl)CC1,benzene_ring1280945,Remove a benzene_ring from the molecule CO[C@@H](C)C(=O)O[C@H](C)c1ccc(C)c([N+](=O)[O-])c1.,CO[C@@H](C)C(=O)O[C@H](C)c1ccc(C)c([N+](=O)[O-])c1,benzene_ring13113549,Please remove a amide from the molecule COc1cccc(-c2cc(C3(C(=O)NC4CC[NH+](Cc5ccccc5)CC4)CC3)no2)c1.,COc1cccc(-c2cc(C3(C(=O)NC4CC[NH+](Cc5ccccc5)CC4)CC3)no2)c1,amide14205850,Remove a halo from the molecule O=C(C1CCC1)N1C[C@@H]2CC[C@H](C1)N(C(=O)c1cc(Cl)ccc1O)C2.,O=C(C1CCC1)N1C[C@@H]2CC[C@H](C1)N(C(=O)c1cc(Cl)ccc1O)C2,halo1595101,Please remove a amide from the molecule CCOc1ccccc1N1C[C@H](C(=O)NC)CC1=O.,CCOc1ccccc1N1C[C@H](C(=O)NC)CC1=O,amide16239829,Remove a amide from the molecule COCCn1ccc2ccc(NC(=O)c3ncccc3OC(C)C)cc21.,COCCn1ccc2ccc(NC(=O)c3ncccc3OC(C)C)cc21,amide1789230,Modify the molecule O=C(Cn1nc(-c2ccccc2F)ccc1=O)c1ccc(Cl)s1 by removing a halo.,O=C(Cn1nc(-c2ccccc2F)ccc1=O)c1ccc(Cl)s1,halo18111718,Please remove a amide from the molecule CCC(C)(C)NC(=O)c1ccc(NC(=O)C(=O)NCC2CCC2)cc1.,CCC(C)(C)NC(=O)c1ccc(NC(=O)C(=O)NCC2CCC2)cc1,amide19126892,Modify the molecule CCOc1ccc(NC(=O)Cc2csc(NC(=O)C3CC3)n2)cc1 by removing a benzene_ring.,CCOc1ccc(NC(=O)Cc2csc(NC(=O)C3CC3)n2)cc1,benzene_ring20244370,Please remove a benzene_ring from the molecule O=C(NC(=S)Nc1cccc(N2CCCC2)c1)c1ccc(Br)cc1.,O=C(NC(=S)Nc1cccc(N2CCCC2)c1)c1ccc(Br)cc1,benzene_ring21124586,Please remove a nitro from the molecule [NH3+]C[C@@H]1CCC[C@@H]1COCc1cc(Cl)ccc1[N+](=O)[O-].,[NH3+]C[C@@H]1CCC[C@@H]1COCc1cc(Cl)ccc1[N+](=O)[O-],nitro22131953,Modify the molecule COc1cccc([C@@H]2C(C#N)=C(N)N(N(C)C)C3=C2C(=O)C[C@@H](c2ccccc2)C3)c1 by removing a amine.,COc1cccc([C@@H]2C(C#N)=C(N)N(N(C)C)C3=C2C(=O)C[C@@H](c2ccccc2)C3)c1,amine23145253,Please remove a halo from the molecule CCC[C@H](C[NH3+])[C@@H](O)c1cc(Cl)c2c(c1)OCCCO2.,CCC[C@H](C[NH3+])[C@@H](O)c1cc(Cl)c2c(c1)OCCCO2,halo24181034,Remove a hydroxyl from the molecule CC(C)[C@H](O)[C@@H](c1ccccc1O)n1nnc2ccccc21.,CC(C)[C@H](O)[C@@H](c1ccccc1O)n1nnc2ccccc21,hydroxyl25111420,Modify the molecule COc1ccc(NC(=O)[C@@H]2CCC[NH+]2Cc2cc(-c3ccccc3)[nH]n2)cc1 by removing a benzene_ring.,COc1ccc(NC(=O)[C@@H]2CCC[NH+]2Cc2cc(-c3ccccc3)[nH]n2)cc1,benzene_ring26209834,Remove a benzene_ring from the molecule COC(=O)c1cccc(SCCS(=O)(=O)c2ccc(C)cc2)c1.,COC(=O)c1cccc(SCCS(=O)(=O)c2ccc(C)cc2)c1,benzene_ring27248810,Remove a amine from the molecule N/C([S-])=[NH+]/Nc1ccc(Cl)c(Cl)c1.,N/C([S-])=[NH+]/Nc1ccc(Cl)c(Cl)c1,amine28117862,Remove a amide from the molecule C=CCCC[C@H](C)[NH+]1CCN(C(=O)Cc2c(C)noc2C)CC1.,C=CCCC[C@H](C)[NH+]1CCN(C(=O)Cc2c(C)noc2C)CC1,amide29101109,Remove a amide from the molecule COCCNC(=O)NC(=O)CNc1cccc(F)c1C.,COCCNC(=O)NC(=O)CNc1cccc(F)c1C,amide3054679,Please remove a benzene_ring from the molecule Cc1nn(Cc2c(Cl)cccc2Cl)c2sc(C(=O)OCc3ncon3)cc12.,Cc1nn(Cc2c(Cl)cccc2Cl)c2sc(C(=O)OCc3ncon3)cc12,benzene_ring31167518,Modify the molecule O=C([O-])CC1(NC(=O)CC2C[C@@H]3CC[C@H](C2)[NH2+]3)CCC1 by removing a amide.,O=C([O-])CC1(NC(=O)CC2C[C@@H]3CC[C@H](C2)[NH2+]3)CCC1,amide32211139,Please remove a amide from the molecule CC(C)NC(=O)c1cc([C@@H]2CN(C(=O)c3ccncc3)CCO2)nc2ccccc12.,CC(C)NC(=O)c1cc([C@@H]2CN(C(=O)c3ccncc3)CCO2)nc2ccccc12,amide336656,Modify the molecule O=C(OCc1cc(-c2ccccc2)on1)c1ccc(F)cc1 by removing a benzene_ring.,O=C(OCc1cc(-c2ccccc2)on1)c1ccc(F)cc1,benzene_ring34194868,Modify the molecule CCS(=O)(=O)CCNC(=O)C1(c2cccc(C)c2)CCCC1 by removing a amide.,CCS(=O)(=O)CCNC(=O)C1(c2cccc(C)c2)CCCC1,amide3547089,Modify the molecule C[C@H](Sc1nccn1-c1cccc(F)c1)C(=O)Nc1ccc2c(c1)OCCO2 by removing a halo.,C[C@H](Sc1nccn1-c1cccc(F)c1)C(=O)Nc1ccc2c(c1)OCCO2,halo36112161,Modify the molecule CC(C)N1C(=O)C[C@@H]([NH+]2CC[C@H](C(=O)[O-])[C@@H]2C)C1=O by removing a amide.,CC(C)N1C(=O)C[C@@H]([NH+]2CC[C@H](C(=O)[O-])[C@@H]2C)C1=O,amide37221214,Please remove a amide from the molecule CCc1c(C)sc2nc(S[C@H](C)C(=O)N3CCCC[C@@H]3CC)n(C[C@@H]3CCCO3)c(=O)c12.,CCc1c(C)sc2nc(S[C@H](C)C(=O)N3CCCC[C@@H]3CC)n(C[C@@H]3CCCO3)c(=O)c12,amide38220385,Remove a amide from the molecule CCOc1ccc(NC(=O)c2sc3nc(C)nc(N4CCC(C)CC4)c3c2C)cc1.,CCOc1ccc(NC(=O)c2sc3nc(C)nc(N4CCC(C)CC4)c3c2C)cc1,amide39163069,Remove a benzene_ring from the molecule C[C@@H](CCc1ccc(O)cc1)NC(=O)N1CCc2ccccc21.,C[C@@H](CCc1ccc(O)cc1)NC(=O)N1CCc2ccccc21,benzene_ring4099508,Please remove a amine from the molecule C[NH+]1[C@H]2CC[C@@H]1CN(C(=O)COc1cccc(N)c1)CC2.,C[NH+]1[C@H]2CC[C@@H]1CN(C(=O)COc1cccc(N)c1)CC2,amine41130517,Please remove a amide from the molecule C=CCNC(=S)NNC(=O)c1cnc(-c2cnn(C)c2)s1.,C=CCNC(=S)NNC(=O)c1cnc(-c2cnn(C)c2)s1,amide42152902,Modify the molecule CCC1(CC)CCN(c2cccc(F)c2C(C)=O)C1 by removing a halo.,CCC1(CC)CCN(c2cccc(F)c2C(C)=O)C1,halo4394604,Remove a amide from the molecule Cc1c(NC(=O)/C=C/c2ccccc2Br)c(=O)n(-c2ccccc2)n1C.,Cc1c(NC(=O)/C=C/c2ccccc2Br)c(=O)n(-c2ccccc2)n1C,amide44237759,Remove a benzene_ring from the molecule c1ccc(-n2cnnc2SCC2CCOCC2)cc1.,c1ccc(-n2cnnc2SCC2CCOCC2)cc1,benzene_ring4582724,Please remove a amine from the molecule O=C([O-])c1cccc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)c1.,O=C([O-])c1cccc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)c1,amine4612679,Please remove a benzene_ring from the molecule CCCNC(=O)CNC(=O)Nc1ccccc1SC1CCCC1.,CCCNC(=O)CNC(=O)Nc1ccccc1SC1CCCC1,benzene_ring4750786,Modify the molecule Cc1ccc([C@](C)(O)CNC(=O)C(=O)Nc2ccc(Cl)cc2)o1 by removing a amide.,Cc1ccc([C@](C)(O)CNC(=O)C(=O)Nc2ccc(Cl)cc2)o1,amide48215018,Please remove a hydroxyl from the molecule CCC[NH+]1CCC(NC(=O)N[C@@H](CO)c2cccc(OC)c2)CC1.,CCC[NH+]1CCC(NC(=O)N[C@@H](CO)c2cccc(OC)c2)CC1,hydroxyl4954702,Remove a benzene_ring from the molecule COc1cccc2c1N(S(=O)(=O)c1ccc(C#N)cc1C)CCC2.,COc1cccc2c1N(S(=O)(=O)c1ccc(C#N)cc1C)CCC2,benzene_ring50141911,Please remove a amide from the molecule COc1ccc(-c2csc(NC(=O)CSc3ccc(NC(C)=O)cc3)n2)cc1.,COc1ccc(-c2csc(NC(=O)CSc3ccc(NC(C)=O)cc3)n2)cc1,amide51196777,Modify the molecule Cc1cnc([C@@H](C)NC(=O)N[C@@H]2C[C@H](C)N(c3ccccc3)C2=O)s1 by removing a amide.,Cc1cnc([C@@H](C)NC(=O)N[C@@H]2C[C@H](C)N(c3ccccc3)C2=O)s1,amide52231735,Please remove a hydroxyl from the molecule O=c1c2cnc3ncnn3c2ccn1CCCO.,O=c1c2cnc3ncnn3c2ccn1CCCO,hydroxyl5319214,Please remove a amine from the molecule Cc1cc(C)c(C(N)=O)c(N[C@H]2C=C[C@H](C(=O)[O-])C2)[nH+]1.,Cc1cc(C)c(C(N)=O)c(N[C@H]2C=C[C@H](C(=O)[O-])C2)[nH+]1,amine54190465,Remove a benzene_ring from the molecule C[C@H](Oc1ccccc1)c1nnc(NC(=O)Nc2cccc(Cl)c2)s1.,C[C@H](Oc1ccccc1)c1nnc(NC(=O)Nc2cccc(Cl)c2)s1,benzene_ring55201410,Remove a halo from the molecule CC(C)Oc1ccc(CNC(=O)[C@@H](C)Oc2ccccc2)cc1F.,CC(C)Oc1ccc(CNC(=O)[C@@H](C)Oc2ccccc2)cc1F,halo56162707,Remove a halo from the molecule CN(C(=O)N[C@H](Cc1ccccc1)c1ccccc1F)C1CCS(=O)CC1.,CN(C(=O)N[C@H](Cc1ccccc1)c1ccccc1F)C1CCS(=O)CC1,halo57159092,Remove a amine from the molecule O=C(CN1CCN(C(=O)[C@@]23CNC[C@@H]2C[NH2+]C3)CC1)N1CCCCC1.,O=C(CN1CCN(C(=O)[C@@]23CNC[C@@H]2C[NH2+]C3)CC1)N1CCCCC1,amine5864474,Modify the molecule Cc1cccc(O[C@@H](C)C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c1 by removing a amide.,Cc1cccc(O[C@@H](C)C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c1,amide59167246,Please remove a hydroxyl from the molecule Cc1ccsc1[C@H](O)[C@@H]1CCOC2(CCSCC2)C1.,Cc1ccsc1[C@H](O)[C@@H]1CCOC2(CCSCC2)C1,hydroxyl6054313,Please remove a halo from the molecule CSC[C@H](CCO)NC(=O)Nc1cc(Br)cn(C)c1=O.,CSC[C@H](CCO)NC(=O)Nc1cc(Br)cn(C)c1=O,halo61166187,Please remove a benzene_ring from the molecule O=C(COc1ccc(-n2cnnn2)cc1)Nc1cccc(S(=O)(=O)N2CCCC2)c1.,O=C(COc1ccc(-n2cnnn2)cc1)Nc1cccc(S(=O)(=O)N2CCCC2)c1,benzene_ring62150511,Remove a hydroxyl from the molecule COc1ccc([C@@H](C)[C@H](C)N[C@@H](CO)c2cc(F)c(F)c(F)c2)cc1.,COc1ccc([C@@H](C)[C@H](C)N[C@@H](CO)c2cc(F)c(F)c(F)c2)cc1,hydroxyl6340740,Remove a amide from the molecule CCn1cc(NC(=O)C[NH+]2CCC[C@H](Cc3nc4ccccc4[nH]3)C2)c(C)n1.,CCn1cc(NC(=O)C[NH+]2CCC[C@H](Cc3nc4ccccc4[nH]3)C2)c(C)n1,amide6480571,Remove a benzene_ring from the molecule CCOC(=O)[C@H]1C(C)=CC(=O)C[C@H]1c1ccccc1.,CCOC(=O)[C@H]1C(C)=CC(=O)C[C@H]1c1ccccc1,benzene_ring65116681,Modify the molecule CCc1nc(C[NH+]2CCC(CNC(=O)C3CC[NH+](C)CC3)CC2)cs1 by removing a amide.,CCc1nc(C[NH+]2CCC(CNC(=O)C3CC[NH+](C)CC3)CC2)cs1,amide66175679,Remove a halo from the molecule Fc1ccc(-c2cn3c(n2)-c2ccccc2C3)cc1.,Fc1ccc(-c2cn3c(n2)-c2ccccc2C3)cc1,halo67197062,Remove a amide from the molecule O=C(CC[NH+]1CCC(C(F)(F)F)CC1)Nc1ccc(F)cc1.,O=C(CC[NH+]1CCC(C(F)(F)F)CC1)Nc1ccc(F)cc1,amide68178309,Remove a amide from the molecule O=C(NCc1ccc(F)cc1F)C1CCN(c2ncnc3c2oc2ccccc23)CC1.,O=C(NCc1ccc(F)cc1F)C1CCN(c2ncnc3c2oc2ccccc23)CC1,amide69212992,Remove a amide from the molecule COc1ccc2c(c1)CCC1=C2N=N[C@@H]1C(=O)N1CC[NH+](C)CC1.,COc1ccc2c(c1)CCC1=C2N=N[C@@H]1C(=O)N1CC[NH+](C)CC1,amide70160405,Remove a benzene_ring from the molecule O=C(NCCc1nc2ccccc2s1)c1ccc(N2CCOCC2)cc1.,O=C(NCCc1nc2ccccc2s1)c1ccc(N2CCOCC2)cc1,benzene_ring71162186,Remove a amide from the molecule Cc1ccc(-n2nc(C(=O)N3CCCC3)c(=O)n(Cc3ccccc3)c2=O)cc1C.,Cc1ccc(-n2nc(C(=O)N3CCCC3)c(=O)n(Cc3ccccc3)c2=O)cc1C,amide7269710,Please remove a amide from the molecule CCc1c(C)sc(NC(=O)[C@H]2CC(C)=C(C)C[C@H]2C(=O)[O-])c1C(=O)NC1CC1.,CCc1c(C)sc(NC(=O)[C@H]2CC(C)=C(C)C[C@H]2C(=O)[O-])c1C(=O)NC1CC1,amide73177502,Modify the molecule O=C(/C=C/c1ccc(Cl)cc1Cl)Nn1cnnc1 by removing a amide.,O=C(/C=C/c1ccc(Cl)cc1Cl)Nn1cnnc1,amide7414220,Modify the molecule O=C(NCCCCN1CCOCC1)C(=O)Nc1cccc(F)c1 by removing a benzene_ring.,O=C(NCCCCN1CCOCC1)C(=O)Nc1cccc(F)c1,benzene_ring75204754,Remove a benzene_ring from the molecule COc1ccc2c(c1OC)C(=O)O[C@@H]2NNC(=O)c1ccccc1Br.,COc1ccc2c(c1OC)C(=O)O[C@@H]2NNC(=O)c1ccccc1Br,benzene_ring76196044,Remove a halo from the molecule C[C@@H]1CCCC[C@@H]1NC(=O)C[NH+]1CCC[C@H](n2c(=O)oc3ccc(Cl)cc32)C1.,C[C@@H]1CCCC[C@@H]1NC(=O)C[NH+]1CCC[C@H](n2c(=O)oc3ccc(Cl)cc32)C1,halo778872,Remove a benzene_ring from the molecule COc1cc(C#N)cc(I)c1OCC(=O)[O-].,COc1cc(C#N)cc(I)c1OCC(=O)[O-],benzene_ring7877677,Remove a hydroxyl from the molecule CC(C)c1nc2sc3c(NCCCO)ncnc3c2c2c1CCCC2.,CC(C)c1nc2sc3c(NCCCO)ncnc3c2c2c1CCCC2,hydroxyl791800,Remove a amide from the molecule Cc1nc(C)c(C(=O)OCC(=O)N[C@H]2CCCc3ccccc32)s1.,Cc1nc(C)c(C(=O)OCC(=O)N[C@H]2CCCc3ccccc32)s1,amide8010928,Please remove a amide from the molecule COc1ccc(NC(=O)[C@@H]2CC(=O)OC2(C)C)cn1.,COc1ccc(NC(=O)[C@@H]2CC(=O)OC2(C)C)cn1,amide8180795,Please remove a halo from the molecule N#C[C@H](NC(=O)[C@H]1CCOc2ccccc21)c1ccc(Cl)c(Cl)c1.,N#C[C@H](NC(=O)[C@H]1CCOc2ccccc21)c1ccc(Cl)c(Cl)c1,halo82183163,Remove a amide from the molecule CCNC(=O)[C@@H]1CCCN(C(=O)N[C@@H](CCCO)c2ccccc2)C1.,CCNC(=O)[C@@H]1CCCN(C(=O)N[C@@H](CCCO)c2ccccc2)C1,amide83145485,Remove a amine from the molecule CC(C)(C)OC(=O)[C@H](N)c1ccnc(C#N)c1.,CC(C)(C)OC(=O)[C@H](N)c1ccnc(C#N)c1,amine84186523,Modify the molecule CCc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1 by removing a amine.,CCc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1,amine8598075,Please remove a amide from the molecule CCCNC(=O)C[C@@H](C[NH3+])N1CC[NH+](C(C)(C)C)CC1.,CCCNC(=O)C[C@@H](C[NH3+])N1CC[NH+](C(C)(C)C)CC1,amide8612410,Modify the molecule COc1cccc(NC(=O)[C@@H](NC(=O)c2ccco2)C(C)C)c1 by removing a amide.,COc1cccc(NC(=O)[C@@H](NC(=O)c2ccco2)C(C)C)c1,amide87136377,Please remove a benzene_ring from the molecule O=C(COC(=O)c1ccccc1Br)NCC(F)(F)F.,O=C(COC(=O)c1ccccc1Br)NCC(F)(F)F,benzene_ring88219376,Remove a benzene_ring from the molecule O=C([O-])CC1(Nc2ccc(C(F)(F)F)cc2)CCC1.,O=C([O-])CC1(Nc2ccc(C(F)(F)F)cc2)CCC1,benzene_ring8991829,Please remove a amide from the molecule COc1ccc2c(c1)=C1CCN3C(=O)CN(Cc4ccco4)C(=O)[C@]3(C)[C@H]1[NH+]=2.,COc1ccc2c(c1)=C1CCN3C(=O)CN(Cc4ccco4)C(=O)[C@]3(C)[C@H]1[NH+]=2,amide90247209,Please remove a hydroxyl from the molecule Cc1ccc(Oc2ccc(NC(=O)N[C@H]3[C@@H](CO)[C@H]4CC[C@@H]3C4)cc2)nn1.,Cc1ccc(Oc2ccc(NC(=O)N[C@H]3[C@@H](CO)[C@H]4CC[C@@H]3C4)cc2)nn1,hydroxyl9174243,Please remove a benzene_ring from the molecule CCOCc1cccc(CNC(=O)c2cccc(NC(N)=O)c2)c1.,CCOCc1cccc(CNC(=O)c2cccc(NC(N)=O)c2)c1,benzene_ring92170586,Remove a halo from the molecule CCOC(=O)[C@H](C)N(C)Cc1c[nH]nc1-c1c(F)cccc1F.,CCOC(=O)[C@H](C)N(C)Cc1c[nH]nc1-c1c(F)cccc1F,halo9367195,Modify the molecule CNS(=O)(=O)c1cc(OC)c(Cl)cc1OC by removing a benzene_ring.,CNS(=O)(=O)c1cc(OC)c(Cl)cc1OC,benzene_ring945990,Please remove a amide from the molecule Cc1ccccc1C(=O)Nc1ccc(OCC(=O)[O-])c(-c2nc3ccccc3s2)c1.,Cc1ccccc1C(=O)Nc1ccc(OCC(=O)[O-])c(-c2nc3ccccc3s2)c1,amide95200020,Remove a benzene_ring from the molecule CCc1cccc(C)c1NC(=O)N[C@@H](C)C[NH+]1CCCCC1.,CCc1cccc(C)c1NC(=O)N[C@@H](C)C[NH+]1CCCCC1,benzene_ring96153121,Modify the molecule O=S(=O)(CC1CCC1)[N-]c1ccc(OC[C@@H]2CCCO2)cc1 by removing a benzene_ring.,O=S(=O)(CC1CCC1)[N-]c1ccc(OC[C@@H]2CCCO2)cc1,benzene_ring97164821,Remove a halo from the molecule COc1ccc(F)cc1C(=O)N(CCc1cccc(F)c1)C1CC1.,COc1ccc(F)cc1C(=O)N(CCc1cccc(F)c1)C1CC1,halo98221605,Modify the molecule Cc1c(Cl)c(C(=O)N2CCOC[C@@H](O)C2)nn1C by removing a amide.,Cc1c(Cl)c(C(=O)N2CCOC[C@@H](O)C2)nn1C,amide99128109,Please remove a amine from the molecule COc1c(C)cnc(CNS(=O)(=O)N2CCCC[C@H]2C)c1C.,COc1c(C)cnc(CNS(=O)(=O)N2CCCC[C@H]2C)c1C,amine100155047,Please remove a benzene_ring from the molecule CCOc1ccc(N2C(=O)O[C@@H](c3ccccc3)[C@]2(O)c2ccccc2)cc1.,CCOc1ccc(N2C(=O)O[C@@H](c3ccccc3)[C@]2(O)c2ccccc2)cc1,benzene_ring101115677,Modify the molecule C[C@@H](C#N)CNC(=O)Nc1ccn(C)n1 by removing a nitrile.,C[C@@H](C#N)CNC(=O)Nc1ccn(C)n1,nitrile10238125,Remove a amide from the molecule O=C1N[C@@H](/C=C/c2ccco2)N2CCOC[C@H]12.,O=C1N[C@@H](/C=C/c2ccco2)N2CCOC[C@H]12,amide103136367,Remove a benzene_ring from the molecule Cc1ccccc1[C@H](CO)CCCS(C)(=O)=O.,Cc1ccccc1[C@H](CO)CCCS(C)(=O)=O,benzene_ring104175475,Please remove a benzene_ring from the molecule COc1ccc(S(=O)(=O)N(C)C(=O)[C@@H](C)c2cccc(F)c2)cc1.,COc1ccc(S(=O)(=O)N(C)C(=O)[C@@H](C)c2cccc(F)c2)cc1,benzene_ring105199100,Remove a benzene_ring from the molecule Cc1cccc(N2N=C(C(=O)NCc3ccccc3)CCC2=O)c1.,Cc1cccc(N2N=C(C(=O)NCc3ccccc3)CCC2=O)c1,benzene_ring10680551,Please remove a benzene_ring from the molecule COc1cccc([C@]2(C(C)(C)C)CCC[NH2+]2)c1.,COc1cccc([C@]2(C(C)(C)C)CCC[NH2+]2)c1,benzene_ring1071796,Please remove a benzene_ring from the molecule CC[C@H](C)NC(=O)CNC(=O)c1ccc(C)c(C)c1.,CC[C@H](C)NC(=O)CNC(=O)c1ccc(C)c(C)c1,benzene_ring10861981,Please remove a halo from the molecule N#C/C(=C\c1cccc(OC2CCCC2)c1)c1ccc(C(F)(F)F)cn1.,N#C/C(=C\c1cccc(OC2CCCC2)c1)c1ccc(C(F)(F)F)cn1,halo10948780,Modify the molecule C[C@H]1CN(C(=O)C[NH+](C)[C@@H](C)c2cccc(NC(=O)c3ccccc3)c2)CCO1 by removing a benzene_ring.,C[C@H]1CN(C(=O)C[NH+](C)[C@@H](C)c2cccc(NC(=O)c3ccccc3)c2)CCO1,benzene_ring110144854,Please remove a amine from the molecule CC[C@@H]1CCCCN1c1ncccc1C(N)=S.,CC[C@@H]1CCCCN1c1ncccc1C(N)=S,amine11119596,Remove a benzene_ring from the molecule COc1cccc(S(=O)(=O)/N=C([O-])/C(C#N)=C\c2ccco2)c1.,COc1cccc(S(=O)(=O)/N=C([O-])/C(C#N)=C\c2ccco2)c1,benzene_ring11228562,Please remove a amide from the molecule CC1=NN(c2ccc(C(=O)N3CCN(Cc4ccsc4)CC3)cc2)CC1.,CC1=NN(c2ccc(C(=O)N3CCN(Cc4ccsc4)CC3)cc2)CC1,amide113109320,Modify the molecule Cc1cc(C)c(C(=O)N[C@@H]2CCCc3ccccc32)c(=O)[nH]1 by removing a amide.,Cc1cc(C)c(C(=O)N[C@@H]2CCCc3ccccc32)c(=O)[nH]1,amide114108288,Please remove a benzene_ring from the molecule CC[C@H]1C[NH+]2CCCC[C@@H]2CN1c1cccc(Cl)c1C.,CC[C@H]1C[NH+]2CCCC[C@@H]2CN1c1cccc(Cl)c1C,benzene_ring115200821,Remove a benzene_ring from the molecule CC[C@H](NC(=O)NC[C@H](O)C1CCOCC1)c1cc(F)ccc1F.,CC[C@H](NC(=O)NC[C@H](O)C1CCOCC1)c1cc(F)ccc1F,benzene_ring116147964,Modify the molecule CCCN[C@]1(C(=O)OC)CC[C@H](n2cc(Cl)cn2)C1 by removing a halo.,CCCN[C@]1(C(=O)OC)CC[C@H](n2cc(Cl)cn2)C1,halo117223895,Modify the molecule COCC[C@]1(C)CC(=O)NC(=O)[C@@H]1C by removing a amide.,COCC[C@]1(C)CC(=O)NC(=O)[C@@H]1C,amide1183843,Remove a amide from the molecule O=C(Nc1ccc(Cl)cc1)c1coc(NC(=O)c2ccco2)n1.,O=C(Nc1ccc(Cl)cc1)c1coc(NC(=O)c2ccco2)n1,amide119123576,Remove a amide from the molecule COC(=O)CCC(=O)Nc1nc(C(C)C)cs1.,COC(=O)CCC(=O)Nc1nc(C(C)C)cs1,amide120135005,Please remove a benzene_ring from the molecule CCCC(=O)N[C@@H]1CCCN(C(=O)[C@H]2CN(Cc3ccccc3)CCO2)C1.,CCCC(=O)N[C@@H]1CCCN(C(=O)[C@H]2CN(Cc3ccccc3)CCO2)C1,benzene_ring12140171,Remove a amide from the molecule O=C(Nc1cccc(NC(=S)Nc2ccccc2)c1)c1ccco1.,O=C(Nc1cccc(NC(=S)Nc2ccccc2)c1)c1ccco1,amide12277346,Please remove a amide from the molecule COCCC(=O)N1CCC[C@@H](C(=O)Nc2ccc(-c3cccc(OC)c3)cc2)C1.,COCCC(=O)N1CCC[C@@H](C(=O)Nc2ccc(-c3cccc(OC)c3)cc2)C1,amide123111617,Please remove a benzene_ring from the molecule Cc1ccc(NC(=O)NC(=O)[C@H](C)[NH2+]CC2(N3CCOCC3)CCCCC2)c(C)c1.,Cc1ccc(NC(=O)NC(=O)[C@H](C)[NH2+]CC2(N3CCOCC3)CCCCC2)c(C)c1,benzene_ring12460033,Remove a amide from the molecule CCCNC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N3C[C@H](C)C[C@@H](C)C3)ccc21.,CCCNC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N3C[C@H](C)C[C@@H](C)C3)ccc21,amide125167157,Please remove a benzene_ring from the molecule CC[NH2+][C@H](Cc1nc(C)c(C)s1)c1cccc(OCC)c1.,CC[NH2+][C@H](Cc1nc(C)c(C)s1)c1cccc(OCC)c1,benzene_ring126144717,Please remove a amide from the molecule COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1C[C@H]1c1cccnc1.,COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1C[C@H]1c1cccnc1,amide127233621,Modify the molecule Cc1c[nH+]c(CNCCO)[nH]1 by removing a amine.,Cc1c[nH+]c(CNCCO)[nH]1,amine128169526,Please remove a amide from the molecule O=C1CCCOc2ccc(C(=O)N3CCc4ccccc4C3)cc21.,O=C1CCCOc2ccc(C(=O)N3CCc4ccccc4C3)cc21,amide12991316,Remove a nitrile from the molecule Cn1c(CN2CCNC[C@@H]2C#N)cc(=O)n(C)c1=O.,Cn1c(CN2CCNC[C@@H]2C#N)cc(=O)n(C)c1=O,nitrile130145969,Please remove a benzene_ring from the molecule NC(=O)[C@H]1CCCN(C(=O)c2cc(F)cc(F)c2)C1.,NC(=O)[C@H]1CCCN(C(=O)c2cc(F)cc(F)c2)C1,benzene_ring131110714,Please remove a amide from the molecule COc1cccc2ccc(C[NH+]3CCc4nnc([C@H](C)NC(=O)C5CC5)n4CC3)nc12.,COc1cccc2ccc(C[NH+]3CCc4nnc([C@H](C)NC(=O)C5CC5)n4CC3)nc12,amide13224036,Please remove a benzene_ring from the molecule COc1ccc([C@H](CNC(=O)Nc2cc(C)ccc2C)[NH+]2CCCC2)cc1.,COc1ccc([C@H](CNC(=O)Nc2cc(C)ccc2C)[NH+]2CCCC2)cc1,benzene_ring13386107,Modify the molecule CCCCN(C)C(=O)N[C@@H](c1ccccn1)c1ccccc1OC by removing a benzene_ring.,CCCCN(C)C(=O)N[C@@H](c1ccccn1)c1ccccc1OC,benzene_ring134163264,Please remove a hydroxyl from the molecule COc1cc(C)c([C@@H](C)[NH2+][C@@H](CO)c2ccc(Cl)cc2)cc1OC.,COc1cc(C)c([C@@H](C)[NH2+][C@@H](CO)c2ccc(Cl)cc2)cc1OC,hydroxyl135187087,Please remove a halo from the molecule Cc1nc(COC(=O)[C@@H](Oc2ccc(F)cc2F)C(C)C)no1.,Cc1nc(COC(=O)[C@@H](Oc2ccc(F)cc2F)C(C)C)no1,halo136213352,Modify the molecule Cc1nc2ccccc2n1-c1ncc(Cl)cc1Cl by removing a halo.,Cc1nc2ccccc2n1-c1ncc(Cl)cc1Cl,halo137165709,Modify the molecule COc1ccc2cc(Br)ccc2c1CC(=O)NNC(=O)c1ccc([N+](=O)[O-])cc1 by removing a benzene_ring.,COc1ccc2cc(Br)ccc2c1CC(=O)NNC(=O)c1ccc([N+](=O)[O-])cc1,benzene_ring138127976,Modify the molecule [NH3+]CCOc1ccc(NC(=O)c2ccccn2)cc1 by removing a amide.,[NH3+]CCOc1ccc(NC(=O)c2ccccn2)cc1,amide139151869,Modify the molecule COc1ccc([C@H](C)N[C@@H](C)C(=O)Nc2ccccc2)c(F)c1 by removing a amine.,COc1ccc([C@H](C)N[C@@H](C)C(=O)Nc2ccccc2)c(F)c1,amine140184041,Please remove a halo from the molecule CC[NH+]1CCN(c2ncnc(Nc3cc(Cl)ccc3Cl)c2[N+](=O)[O-])CC1.,CC[NH+]1CCN(c2ncnc(Nc3cc(Cl)ccc3Cl)c2[N+](=O)[O-])CC1,halo14111269,Modify the molecule COc1ccccc1C[NH2+]CC1(N(C)C)CCOCC1 by removing a benzene_ring.,COc1ccccc1C[NH2+]CC1(N(C)C)CCOCC1,benzene_ring142164891,Please remove a benzene_ring from the molecule C[C@H]([NH2+]Cc1ccc(OC(F)(F)F)cc1)c1ccc(-n2cncn2)cc1.,C[C@H]([NH2+]Cc1ccc(OC(F)(F)F)cc1)c1ccc(-n2cncn2)cc1,benzene_ring14344507,Remove a benzene_ring from the molecule CC1(C)CCN(C(=O)[C@H](c2ccccc2)N2CCSCC2)C1.,CC1(C)CCN(C(=O)[C@H](c2ccccc2)N2CCSCC2)C1,benzene_ring144159151,Please remove a amide from the molecule Cc1cccc2sc(NC(=O)[C@@H]3C[C@@H]3C)nc12.,Cc1cccc2sc(NC(=O)[C@@H]3C[C@@H]3C)nc12,amide14591444,Remove a amide from the molecule C[C@@H](C(=O)OCC(=O)N1CCCCC1)N1C(=O)c2ccccc2C1=O.,C[C@@H](C(=O)OCC(=O)N1CCCCC1)N1C(=O)c2ccccc2C1=O,amide146211205,Remove a hydroxyl from the molecule CSc1ccc(C(=O)[C@@H]2CCC[NH+](Cc3ccc(C#CC(C)(C)O)s3)C2)cc1.,CSc1ccc(C(=O)[C@@H]2CCC[NH+](Cc3ccc(C#CC(C)(C)O)s3)C2)cc1,hydroxyl14742213,Please remove a benzene_ring from the molecule O=C(Nc1ccccc1C(=O)N1CCCCC1)c1cccs1.,O=C(Nc1ccccc1C(=O)N1CCCCC1)c1cccs1,benzene_ring148164760,Please remove a halo from the molecule COc1cc([C@H](O)c2cc(F)c(F)c(F)c2)ccc1Cl.,COc1cc([C@H](O)c2cc(F)c(F)c(F)c2)ccc1Cl,halo14998529,Please remove a benzene_ring from the molecule CC[C@H](CSC)N(C)C(=O)NCc1ccc(OC)c(Cl)c1.,CC[C@H](CSC)N(C)C(=O)NCc1ccc(OC)c(Cl)c1,benzene_ring150201989,Remove a amide from the molecule CCn1cc(C(=O)C(=O)NC2CC(C)(C)[NH2+]C(C)(C)C2)cn1.,CCn1cc(C(=O)C(=O)NC2CC(C)(C)[NH2+]C(C)(C)C2)cn1,amide1518226,Modify the molecule O=C1C[C@H](C(=O)NCCC2=CCCCC2)Cc2nc(NC(=O)c3c(F)cccc3Cl)sc21 by removing a benzene_ring.,O=C1C[C@H](C(=O)NCCC2=CCCCC2)Cc2nc(NC(=O)c3c(F)cccc3Cl)sc21,benzene_ring152192529,Remove a amide from the molecule CCc1cc(N2CCC(NC(=O)C3C[C@@H](C)O[C@H](C)C3)CC2)ncn1.,CCc1cc(N2CCC(NC(=O)C3C[C@@H](C)O[C@H](C)C3)CC2)ncn1,amide153227697,Remove a benzene_ring from the molecule NC(=O)C[C@H](C(=O)[O-])N1C(=O)/C(=C/c2ccccc2)SC1=S.,NC(=O)C[C@H](C(=O)[O-])N1C(=O)/C(=C/c2ccccc2)SC1=S,benzene_ring154179613,Remove a amide from the molecule Cc1cccnc1C[NH+]1CCC[C@H](C(=O)N(C)C)C1.,Cc1cccnc1C[NH+]1CCC[C@H](C(=O)N(C)C)C1,amide155150430,Modify the molecule CC[NH2+][C@H]1CC[C@@H](SC[C@@H](C)CO)C1 by removing a hydroxyl.,CC[NH2+][C@H]1CC[C@@H](SC[C@@H](C)CO)C1,hydroxyl156158,Modify the molecule COc1ccc([C@@H]([NH2+]Cc2ccc(Cl)nc2)c2ccc(F)cc2)cc1 by removing a halo.,COc1ccc([C@@H]([NH2+]Cc2ccc(Cl)nc2)c2ccc(F)cc2)cc1,halo157134912,Remove a amide from the molecule C[C@H]1C[C@H]1C(=O)N1CCN(Cc2csc(CC(=O)N(C)C)n2)CC1.,C[C@H]1C[C@H]1C(=O)N1CCN(Cc2csc(CC(=O)N(C)C)n2)CC1,amide158163661,Please remove a amide from the molecule Cc1ccc([C@H](C)NC(=O)CC2(C(=O)[O-])CCCC2)o1.,Cc1ccc([C@H](C)NC(=O)CC2(C(=O)[O-])CCCC2)o1,amide159175871,Modify the molecule Cc1ccc(NC(=O)C2CCC(N3C(=O)[C@H]4[C@H]5CC[C@H](C5)[C@H]4C3=O)CC2)cc1 by removing a amide.,Cc1ccc(NC(=O)C2CCC(N3C(=O)[C@H]4[C@H]5CC[C@H](C5)[C@H]4C3=O)CC2)cc1,amide16031076,Remove a benzene_ring from the molecule CCOCc1ccccc1NC(=O)c1ccc(-c2cscn2)cc1.,CCOCc1ccccc1NC(=O)c1ccc(-c2cscn2)cc1,benzene_ring161140319,Modify the molecule C[C@@H](CCc1ccco1)[NH2+]C[C@](C)(O)c1ccc(F)cc1F by removing a halo.,C[C@@H](CCc1ccco1)[NH2+]C[C@](C)(O)c1ccc(F)cc1F,halo16281274,Modify the molecule N#Cc1ccc(Cc2cnc(N)s2)cc1 by removing a amine.,N#Cc1ccc(Cc2cnc(N)s2)cc1,amine16336847,Please remove a amine from the molecule O=[N+]([O-])c1ccc(F)c2c1[C@H]1C=CC[C@H]1[C@H](c1cccnc1)N2.,O=[N+]([O-])c1ccc(F)c2c1[C@H]1C=CC[C@H]1[C@H](c1cccnc1)N2,amine164223814,Remove a amide from the molecule CCN(C(=O)[C@@H]1CC(=O)N(c2ccccc2Cl)C1)[C@H](C)c1cccc(OC)c1.,CCN(C(=O)[C@@H]1CC(=O)N(c2ccccc2Cl)C1)[C@H](C)c1cccc(OC)c1,amide165191188,Please remove a benzene_ring from the molecule C[C@H](NC(=O)[C@@H]1CCC[NH+](C)C1)c1ccc(NC(=O)NC2CC2)cc1.,C[C@H](NC(=O)[C@@H]1CCC[NH+](C)C1)c1ccc(NC(=O)NC2CC2)cc1,benzene_ring1661487,Remove a halo from the molecule CSc1ccc2c(C)cc(N3CCO[C@@H](C(F)(F)F)C3)nc2c1.,CSc1ccc2c(C)cc(N3CCO[C@@H](C(F)(F)F)C3)nc2c1,halo167101368,Please remove a amide from the molecule CO[C@@H](CNC(=O)Nc1ccc(N(C)C(C)=O)cc1)c1ccc(F)cc1.,CO[C@@H](CNC(=O)Nc1ccc(N(C)C(C)=O)cc1)c1ccc(F)cc1,amide16824927,Please remove a amide from the molecule C[C@H](CNC(=O)c1ccn(-c2ccccc2F)n1)c1ccsc1.,C[C@H](CNC(=O)c1ccn(-c2ccccc2F)n1)c1ccsc1,amide169185091,Modify the molecule CN(C)S(=O)(=O)c1ccc(NC(=O)CSc2nnc(-c3ccc(F)cc3)o2)cc1 by removing a benzene_ring.,CN(C)S(=O)(=O)c1ccc(NC(=O)CSc2nnc(-c3ccc(F)cc3)o2)cc1,benzene_ring170232673,Please remove a amine from the molecule CN(C(=O)[O-])c1ccc2c(c1)CCN2.,CN(C(=O)[O-])c1ccc2c(c1)CCN2,amine171134392,Remove a amide from the molecule C[C@@H]1CC([NH+]2CCN(CC(=O)N3CCCCC3)CC2)C[C@@H](C)C1.,C[C@@H]1CC([NH+]2CCN(CC(=O)N3CCCCC3)CC2)C[C@@H](C)C1,amide17253275,Remove a amide from the molecule CN(C)C(=O)CN(C)C(=O)c1cc2ccccc2[nH]1.,CN(C)C(=O)CN(C)C(=O)c1cc2ccccc2[nH]1,amide17339033,Remove a nitrile from the molecule CC(=O)[C@@H]1[C@@H](c2ccc(F)cc2F)C(C#N)(C#N)[C@H]2c3ccccc3C=CN12.,CC(=O)[C@@H]1[C@@H](c2ccc(F)cc2F)C(C#N)(C#N)[C@H]2c3ccccc3C=CN12,nitrile17490225,Remove a benzene_ring from the molecule C[C@@H]1CCN(C(=O)N[C@@H](CS(C)(=O)=O)c2ccccc2)C[C@H](C)C1.,C[C@@H]1CCN(C(=O)N[C@@H](CS(C)(=O)=O)c2ccccc2)C[C@H](C)C1,benzene_ring175112651,Remove a amide from the molecule CCc1nn(C)c(OC)c1CNC(=O)CCN1c2ccccc2CC[C@@H]1C.,CCc1nn(C)c(OC)c1CNC(=O)CCN1c2ccccc2CC[C@@H]1C,amide176138912,Please remove a amine from the molecule CC(C)Nc1cc2ccccc2cc1C(=O)[O-].,CC(C)Nc1cc2ccccc2cc1C(=O)[O-],amine17788403,Please remove a halo from the molecule CC(C)(C)OC(=O)N1CCC[C@@H](CCOCc2ccc(Cl)nn2)C1.,CC(C)(C)OC(=O)N1CCC[C@@H](CCOCc2ccc(Cl)nn2)C1,halo178246686,Remove a amine from the molecule C[C@@]12CCCC[C@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)/C(=N/N)CC[C@H]12.,C[C@@]12CCCC[C@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)/C(=N/N)CC[C@H]12,amine17994134,Modify the molecule Cc1csc(C[S@@](=O)c2ccccc2F)n1 by removing a benzene_ring.,Cc1csc(C[S@@](=O)c2ccccc2F)n1,benzene_ring18038010,Remove a halo from the molecule O=C([O-])c1nn(-c2ccc(Br)cc2)c(=O)c2ccccc12.,O=C([O-])c1nn(-c2ccc(Br)cc2)c(=O)c2ccccc12,halo181227342,Remove a benzene_ring from the molecule CCCOc1ccccc1NC(=O)C(=O)NC[C@@H]1CCC[C@@H]1O.,CCCOc1ccccc1NC(=O)C(=O)NC[C@@H]1CCC[C@@H]1O,benzene_ring182201716,Please remove a amide from the molecule CCCc1[nH]nc(C(=O)Nc2cnc(-c3ccccc3)s2)c1[N+](=O)[O-].,CCCc1[nH]nc(C(=O)Nc2cnc(-c3ccccc3)s2)c1[N+](=O)[O-],amide183178188,Remove a amide from the molecule O=C1C[C@H](N2CCN(c3ccc(O)cc3)CC2)C(=O)N1c1cccc(Cl)c1.,O=C1C[C@H](N2CCN(c3ccc(O)cc3)CC2)C(=O)N1c1cccc(Cl)c1,amide18496056,Modify the molecule CC(C)CNC(=O)c1c(N)n(/N=C/c2ccc(F)cc2)c2nc3ccccc3nc12 by removing a halo.,CC(C)CNC(=O)c1c(N)n(/N=C/c2ccc(F)cc2)c2nc3ccccc3nc12,halo185217036,Please remove a benzene_ring from the molecule NC(=O)[C@H]1CN(S(=O)(=O)c2ccccc2)CCN1S(=O)(=O)c1ccccc1.,NC(=O)[C@H]1CN(S(=O)(=O)c2ccccc2)CCN1S(=O)(=O)c1ccccc1,benzene_ring18696293,Modify the molecule CCc1nc2ncc3c(n2n1)C[C@@H](c1ccccc1C)CC3=O by removing a benzene_ring.,CCc1nc2ncc3c(n2n1)C[C@@H](c1ccccc1C)CC3=O,benzene_ring187240132,Please remove a benzene_ring from the molecule CCc1ccc(C(=O)Cc2ccc([N+](=O)[O-])cc2)o1.,CCc1ccc(C(=O)Cc2ccc([N+](=O)[O-])cc2)o1,benzene_ring188145284,Please remove a amide from the molecule COc1cccc([C@@H]2CCC[NH+]2CCCN2C(=O)NC(C)(C)C2=O)c1.,COc1cccc([C@@H]2CCC[NH+]2CCCN2C(=O)NC(C)(C)C2=O)c1,amide18963031,Modify the molecule CC(C)(CNC(=O)CCC(F)(F)F)c1ccccc1F by removing a halo.,CC(C)(CNC(=O)CCC(F)(F)F)c1ccccc1F,halo19075232,Remove a amide from the molecule CSc1cccc2sc(N3CCN(C(=O)C(C)C)CC3)nc12.,CSc1cccc2sc(N3CCN(C(=O)C(C)C)CC3)nc12,amide19194343,Remove a hydroxyl from the molecule C[C@H](O)[C@@H](C)N1CC[NH2+]CC1(C)C.,C[C@H](O)[C@@H](C)N1CC[NH2+]CC1(C)C,hydroxyl192117110,Remove a halo from the molecule C=C(Cl)CN(C(=O)Cc1c(C)noc1C)[C@H]1CCc2ccccc21.,C=C(Cl)CN(C(=O)Cc1c(C)noc1C)[C@H]1CCc2ccccc21,halo193180180,Please remove a benzene_ring from the molecule CC(=O)c1ccc(S(=O)(=O)N(C)CC(=O)N[C@H]2C[C@@H]2C)cc1.,CC(=O)c1ccc(S(=O)(=O)N(C)CC(=O)N[C@H]2C[C@@H]2C)cc1,benzene_ring194111311,Remove a benzene_ring from the molecule COc1ccc(Nc2nnc(SCC(=O)c3ccc[nH]3)s2)cc1.,COc1ccc(Nc2nnc(SCC(=O)c3ccc[nH]3)s2)cc1,benzene_ring195232608,Remove a benzene_ring from the molecule CCC(=O)N1CCC[C@H]1c1nc2ccccc2n1CCOc1ccc(Cl)c(C)c1.,CCC(=O)N1CCC[C@H]1c1nc2ccccc2n1CCOc1ccc(Cl)c(C)c1,benzene_ring196115125,Modify the molecule CCN(Cc1ccccc1)C(=O)c1ccccc1NC(=O)c1ccccc1 by removing a benzene_ring.,CCN(Cc1ccccc1)C(=O)c1ccccc1NC(=O)c1ccccc1,benzene_ring197116916,Remove a halo from the molecule C[C@H](CNCc1cccc(F)c1)c1ccsc1.,C[C@H](CNCc1cccc(F)c1)c1ccsc1,halo19882301,Modify the molecule CCOC(=O)c1c(NC(=O)c2ccc(C)cc2)sc2c1CC[NH+](C(C)C)C2 by removing a benzene_ring.,CCOC(=O)c1c(NC(=O)c2ccc(C)cc2)sc2c1CC[NH+](C(C)C)C2,benzene_ring19912666,Please remove a amide from the molecule Cc1ccc2ncc(C(=O)Nc3nnc(CC(C)C)s3)n2c1.,Cc1ccc2ncc(C(=O)Nc3nnc(CC(C)C)s3)n2c1,amide200140222,Modify the molecule Cc1noc(C)c1[C@H](C)NC(=O)[C@@H](C)C[NH3+] by removing a amide.,Cc1noc(C)c1[C@H](C)NC(=O)[C@@H](C)C[NH3+],amide201203995,Modify the molecule COc1ccc(NC(=O)C2=Cc3ccccc3OC2)cc1 by removing a benzene_ring.,COc1ccc(NC(=O)C2=Cc3ccccc3OC2)cc1,benzene_ring202157830,Remove a amide from the molecule COC[C@@H]1CN(CCC(=O)N2CCC[C@H]2C)CCO1.,COC[C@@H]1CN(CCC(=O)N2CCC[C@H]2C)CCO1,amide20382382,Remove a amine from the molecule CCS(=O)(=O)NCCc1cc2c(C)ccc(C)c2[nH]c1=O.,CCS(=O)(=O)NCCc1cc2c(C)ccc(C)c2[nH]c1=O,amine20493578,Modify the molecule Cc1cc(N2CCC[C@H](C(=O)c3ccc(F)cc3)C2)ncc1[N+](=O)[O-] by removing a benzene_ring.,Cc1cc(N2CCC[C@H](C(=O)c3ccc(F)cc3)C2)ncc1[N+](=O)[O-],benzene_ring20510060,Modify the molecule Cc1nn(-c2ccccc2F)c2ncc3c(c12)C(=O)N(c1ccc(C(C)C)cc1)C3=O by removing a halo.,Cc1nn(-c2ccccc2F)c2ncc3c(c12)C(=O)N(c1ccc(C(C)C)cc1)C3=O,halo206221599,Please remove a benzene_ring from the molecule CC(=O)N1CC[C@@H](c2c(C(=O)Nc3cccc(OC(C)C)c3)sc3ccccc23)C1.,CC(=O)N1CC[C@@H](c2c(C(=O)Nc3cccc(OC(C)C)c3)sc3ccccc23)C1,benzene_ring20744621,Please remove a benzene_ring from the molecule CCOc1cc(C)ccc1NC(=O)c1cccc(NC(=O)c2cccs2)c1.,CCOc1cc(C)ccc1NC(=O)c1cccc(NC(=O)c2cccs2)c1,benzene_ring20847584,Please remove a amine from the molecule CCOc1ccc(S(=O)(=O)NC[C@H](C)C#N)cc1.,CCOc1ccc(S(=O)(=O)NC[C@H](C)C#N)cc1,amine20914007,Remove a benzene_ring from the molecule C[C@H](CC(=O)N[C@H](C)c1nc2ccccc2[nH]1)Cc1cccc(F)c1.,C[C@H](CC(=O)N[C@H](C)c1nc2ccccc2[nH]1)Cc1cccc(F)c1,benzene_ring210178339,Modify the molecule CCc1nc(-c2cc(C)[nH+]c3ccccc23)nc([O-])c1Br by removing a halo.,CCc1nc(-c2cc(C)[nH+]c3ccccc23)nc([O-])c1Br,halo211232970,Remove a halo from the molecule CN(Cc1ccccc1)S(=O)(=O)c1cc(C(=O)Nc2ccc(Br)cc2)ccc1F.,CN(Cc1ccccc1)S(=O)(=O)c1cc(C(=O)Nc2ccc(Br)cc2)ccc1F,halo212220560,Modify the molecule CC[C@@H](C)[C@@]1(O)CSCC(C)(C)C1 by removing a hydroxyl.,CC[C@@H](C)[C@@]1(O)CSCC(C)(C)C1,hydroxyl21351392,Remove a benzene_ring from the molecule CCN(c1ccccc1)c1[nH+]cnc(Nc2nc3ccccc3s2)c1N.,CCN(c1ccccc1)c1[nH+]cnc(Nc2nc3ccccc3s2)c1N,benzene_ring214154647,Modify the molecule CC(C)Oc1ccccc1NC(=O)Cc1csc(-c2ccoc2)n1 by removing a benzene_ring.,CC(C)Oc1ccccc1NC(=O)Cc1csc(-c2ccoc2)n1,benzene_ring21597482,Modify the molecule C[NH+](Cc1ccccc1NC(=O)NC[C@H](O)c1ccco1)C1CCCCC1 by removing a benzene_ring.,C[NH+](Cc1ccccc1NC(=O)NC[C@H](O)c1ccco1)C1CCCCC1,benzene_ring216190597,Please remove a benzene_ring from the molecule COC(=O)[C@@H](c1cccc(Br)c1)N(C)CC1=CCCOC1.,COC(=O)[C@@H](c1cccc(Br)c1)N(C)CC1=CCCOC1,benzene_ring217171299,Modify the molecule C[C@@H](CSC(C)(C)C)[NH2+]C[C@]1(O)CCc2ccccc21 by removing a hydroxyl.,C[C@@H](CSC(C)(C)C)[NH2+]C[C@]1(O)CCc2ccccc21,hydroxyl218201753,Please remove a amide from the molecule O=C(Cn1c(=O)cnc2ccccc21)N[C@H]1C[C@@H]2CCCc3cccc1c32.,O=C(Cn1c(=O)cnc2ccccc21)N[C@H]1C[C@@H]2CCCc3cccc1c32,amide219245517,Please remove a benzene_ring from the molecule CCS(=O)(=O)[N-]c1ccc(C(=O)/C=C/c2ccc(C)c(F)c2)cc1.,CCS(=O)(=O)[N-]c1ccc(C(=O)/C=C/c2ccc(C)c(F)c2)cc1,benzene_ring22089835,Please remove a amide from the molecule Cc1ccc(OC(=O)N2CCN3C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]3C2)cc1.,Cc1ccc(OC(=O)N2CCN3C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]3C2)cc1,amide221171158,Modify the molecule CCOc1ccc(C(=O)CC(F)(F)F)c(Br)c1 by removing a halo.,CCOc1ccc(C(=O)CC(F)(F)F)c(Br)c1,halo222224402,Please remove a amine from the molecule COC(=O)c1cc(N)ccc1N1CCCCC1.,COC(=O)c1cc(N)ccc1N1CCCCC1,amine223233105,Modify the molecule COc1cccc(N2CC[NH+]([C@H](C)c3nc(C(C)(C)C)no3)CC2)c1 by removing a benzene_ring.,COc1cccc(N2CC[NH+]([C@H](C)c3nc(C(C)(C)C)no3)CC2)c1,benzene_ring224211193,Remove a amide from the molecule CCCC(=O)Nc1cccc(C(=O)Nc2ccccn2)c1.,CCCC(=O)Nc1cccc(C(=O)Nc2ccccn2)c1,amide225211399,Modify the molecule C[C@H](NC(=O)C(=O)Nc1cc(F)cc(F)c1)C(=O)NCc1ccco1 by removing a halo.,C[C@H](NC(=O)C(=O)Nc1cc(F)cc(F)c1)C(=O)NCc1ccco1,halo226139627,Please remove a benzene_ring from the molecule Cc1nc(C(C)(C)c2ccccc2)sc1C(=O)NCc1ncoc1C.,Cc1nc(C(C)(C)c2ccccc2)sc1C(=O)NCc1ncoc1C,benzene_ring227150825,Please remove a amide from the molecule Cc1ccc(S(=O)(=O)c2ncsc2SCC(=O)NCc2ccc(C)o2)cc1.,Cc1ccc(S(=O)(=O)c2ncsc2SCC(=O)NCc2ccc(C)o2)cc1,amide22853880,Please remove a amide from the molecule Cc1nc(C[NH+]2CCC[C@H](CNC(=O)c3ccccc3)C2)sc1C.,Cc1nc(C[NH+]2CCC[C@H](CNC(=O)c3ccccc3)C2)sc1C,amide22920057,Remove a benzene_ring from the molecule CCn1cnnc1[C@@H]1CCCN(C(=O)Nc2ccc(OC)cc2)C1.,CCn1cnnc1[C@@H]1CCCN(C(=O)Nc2ccc(OC)cc2)C1,benzene_ring230232684,Modify the molecule CS(=O)(=O)c1ccc(C(=O)N2C[C@@H](C(=O)[O-])[C@H](c3ccncc3)C2)cc1 by removing a amide.,CS(=O)(=O)c1ccc(C(=O)N2C[C@@H](C(=O)[O-])[C@H](c3ccncc3)C2)cc1,amide23168106,Modify the molecule CN[C@@](C)(c1ccoc1)C(F)(F)F by removing a halo.,CN[C@@](C)(c1ccoc1)C(F)(F)F,halo23299379,Modify the molecule O=C1NC(=S)NC(=O)C1=CNCCc1ccc(F)cc1 by removing a benzene_ring.,O=C1NC(=S)NC(=O)C1=CNCCc1ccc(F)cc1,benzene_ring23320520,Modify the molecule Cc1nc(NC(=O)CCn2c([S-])nnc2-c2cccs2)sc1C by removing a amide.,Cc1nc(NC(=O)CCn2c([S-])nnc2-c2cccs2)sc1C,amide234221860,Remove a benzene_ring from the molecule O=C(/C=C1/Sc2ccccc2N(Cc2ccccc2F)C1=O)NCc1ccc2c(c1)OCO2.,O=C(/C=C1/Sc2ccccc2N(Cc2ccccc2F)C1=O)NCc1ccc2c(c1)OCO2,benzene_ring235153806,Please remove a halo from the molecule COc1ccccc1OCCCOc1ccc(F)cc1.,COc1ccccc1OCCCOc1ccc(F)cc1,halo236224265,Modify the molecule O=C(Nc1ccc(NC(=O)[C@@H]2CCCO2)cc1)c1cccnc1 by removing a benzene_ring.,O=C(Nc1ccc(NC(=O)[C@@H]2CCCO2)cc1)c1cccnc1,benzene_ring23799991,Please remove a amide from the molecule C[C@H]1C[C@H](Nc2ccc(NC(=O)C[NH+](C)C)cc2)C(=O)O1.,C[C@H]1C[C@H](Nc2ccc(NC(=O)C[NH+](C)C)cc2)C(=O)O1,amide238230837,Remove a amine from the molecule Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ncnc4sccc34)cc2)cc1.,Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ncnc4sccc34)cc2)cc1,amine23934415,Remove a amide from the molecule O=C(NCc1csc(=O)[nH]1)c1coc(-c2ccccc2)n1.,O=C(NCc1csc(=O)[nH]1)c1coc(-c2ccccc2)n1,amide240123592,Remove a benzene_ring from the molecule Cc1ccc(C(=O)N[C@@H]2C[C@H]3CC[C@]2(C)C3(C)C)cc1.,Cc1ccc(C(=O)N[C@@H]2C[C@H]3CC[C@]2(C)C3(C)C)cc1,benzene_ring241243030,Remove a amine from the molecule CC(N[C@H]1CCCC[C@@H]1C)=C1C(=O)NC(=S)NC1=O.,CC(N[C@H]1CCCC[C@@H]1C)=C1C(=O)NC(=S)NC1=O,amine24279276,Remove a benzene_ring from the molecule CC(C)c1ccc([C@@H](C)[NH2+]Cc2cnn(C)c2)cc1.,CC(C)c1ccc([C@@H](C)[NH2+]Cc2cnn(C)c2)cc1,benzene_ring24321905,Modify the molecule COc1ccc(C(=O)NCc2ccc(-c3nn4cnnc4s3)cc2)cc1OC by removing a amide.,COc1ccc(C(=O)NCc2ccc(-c3nn4cnnc4s3)cc2)cc1OC,amide24471916,Remove a halo from the molecule O=C(Nc1ccc2c(c1)OCCO2)N1CCN(c2ccc(Cl)c(Cl)c2)CC1.,O=C(Nc1ccc2c(c1)OCCO2)N1CCN(c2ccc(Cl)c(Cl)c2)CC1,halo245152848,Remove a benzene_ring from the molecule O=C(NOCc1ccccc1)N1CCC(c2nc3ccccc3s2)CC1.,O=C(NOCc1ccccc1)N1CCC(c2nc3ccccc3s2)CC1,benzene_ring24629264,Please remove a benzene_ring from the molecule Cc1ccc(C(CO)(CO)CCSc2ccccc2)cc1.,Cc1ccc(C(CO)(CO)CCSc2ccccc2)cc1,benzene_ring247183946,Remove a amide from the molecule Cc1ccc([N+](=O)[O-])cc1NC(=O)c1cccc(OCCC(C)C)c1.,Cc1ccc([N+](=O)[O-])cc1NC(=O)c1cccc(OCCC(C)C)c1,amide248244301,Remove a amide from the molecule CC(C)[C@H](C(=O)Nc1ccc(C(=O)N(C)C)cc1)c1ccc(Cl)cc1.,CC(C)[C@H](C(=O)Nc1ccc(C(=O)N(C)C)cc1)c1ccc(Cl)cc1,amide24954689,Remove a amide from the molecule CC(C)[C@H](C)CC(=O)N1CCc2cc([N+](=O)[O-])ccc21.,CC(C)[C@H](C)CC(=O)N1CCc2cc([N+](=O)[O-])ccc21,amide25029878,Modify the molecule CN(C[C@@H]1CCOC1)C(=O)Nc1ccc(Cl)c(CS(C)(=O)=O)c1 by removing a halo.,CN(C[C@@H]1CCOC1)C(=O)Nc1ccc(Cl)c(CS(C)(=O)=O)c1,halo251158767,Modify the molecule CCn1c(CCNC(=O)C2(c3ccc(C(C)C)cc3)CCCC2)n[nH]c1=S by removing a benzene_ring.,CCn1c(CCNC(=O)C2(c3ccc(C(C)C)cc3)CCCC2)n[nH]c1=S,benzene_ring25296802,Please remove a amine from the molecule C[C@H](Oc1ccc(Cl)cc1Cl)C(=O)NC(=S)Nc1ccccc1F.,C[C@H](Oc1ccc(Cl)cc1Cl)C(=O)NC(=S)Nc1ccccc1F,amine25331213,Remove a amide from the molecule C[C@@H](SCC1=NC(=O)C2=C3CCCC[C@@H]3SC2=N1)C(=O)NC1CC1.,C[C@@H](SCC1=NC(=O)C2=C3CCCC[C@@H]3SC2=N1)C(=O)NC1CC1,amide25484509,Modify the molecule C=CCOc1ccccc1CN1CCNC(=O)[C@@H]1c1ccccc1 by removing a amide.,C=CCOc1ccccc1CN1CCNC(=O)[C@@H]1c1ccccc1,amide25548716,Modify the molecule O=C([O-])C[C@H]1C(=O)NCCN1C(=O)CC1CCCC1 by removing a amide.,O=C([O-])C[C@H]1C(=O)NCCN1C(=O)CC1CCCC1,amide256222258,Remove a amide from the molecule CCc1cc(C(F)(F)F)c2c(C3CCN(C(=O)c4cn(C)nc4C)CC3)noc2n1.,CCc1cc(C(F)(F)F)c2c(C3CCN(C(=O)c4cn(C)nc4C)CC3)noc2n1,amide257134818,Remove a halo from the molecule Nc1cnc(N(Cc2cccs2)C2CC2)c(Br)c1.,Nc1cnc(N(Cc2cccs2)C2CC2)c(Br)c1,halo25892415,Remove a benzene_ring from the molecule COc1cccc(/N=C(\O)[C@H](C)Sc2nncn2-c2ccccc2)c1.,COc1cccc(/N=C(\O)[C@H](C)Sc2nncn2-c2ccccc2)c1,benzene_ring259215341,Modify the molecule CC1(C)CC(NCCC(N)=O)CC(C)(C)[NH2+]1 by removing a amide.,CC1(C)CC(NCCC(N)=O)CC(C)(C)[NH2+]1,amide260137966,Remove a halo from the molecule C[C@H]1CCCN(C(=O)Nc2ccc(CCC(F)(F)F)cc2)[C@H]1CO.,C[C@H]1CCCN(C(=O)Nc2ccc(CCC(F)(F)F)cc2)[C@H]1CO,halo261215190,Remove a halo from the molecule COc1cccc2sc(N(C[C@H]3CCCO3)C(=O)c3ccc(Cl)cc3)nc12.,COc1cccc2sc(N(C[C@H]3CCCO3)C(=O)c3ccc(Cl)cc3)nc12,halo262190880,Please remove a amide from the molecule CCN(Cc1ccc(OC)c(OC)c1)C(=O)CN1C[C@@H](C)O[C@H](C)C1.,CCN(Cc1ccc(OC)c(OC)c1)C(=O)CN1C[C@@H](C)O[C@H](C)C1,amide2639486,Remove a amide from the molecule Cc1cc(NC(=O)C2CCN(C(=O)N3CCCC3)CC2)no1.,Cc1cc(NC(=O)C2CCN(C(=O)N3CCCC3)CC2)no1,amide26441012,Please remove a amide from the molecule Cc1ccccc1NS(=O)(=O)c1ccc2[nH]cc(C(=O)N[C@@H]3CCCC[C@@H]3C)c(=O)c2c1.,Cc1ccccc1NS(=O)(=O)c1ccc2[nH]cc(C(=O)N[C@@H]3CCCC[C@@H]3C)c(=O)c2c1,amide26543394,Please remove a benzene_ring from the molecule Cc1cc(/C=C2/C(=O)NC(=S)N=C2[O-])c(C)n1-c1cccc(C(=O)[O-])c1.,Cc1cc(/C=C2/C(=O)NC(=S)N=C2[O-])c(C)n1-c1cccc(C(=O)[O-])c1,benzene_ring266138550,Please remove a benzene_ring from the molecule O=C(CCc1ccccc1)[C@@H]1CCCN(C(=O)CN2CCCCCC2=O)C1.,O=C(CCc1ccccc1)[C@@H]1CCCN(C(=O)CN2CCCCCC2=O)C1,benzene_ring26767985,Modify the molecule C=CCSCC(=O)N[C@@H](C)C(=O)OC by removing a amide.,C=CCSCC(=O)N[C@@H](C)C(=O)OC,amide26827276,Modify the molecule OC1CCC([NH2+][C@H]2CCCc3ccc(Br)cc32)CC1 by removing a hydroxyl.,OC1CCC([NH2+][C@H]2CCCc3ccc(Br)cc32)CC1,hydroxyl26989483,Remove a halo from the molecule C[C@]1([C@H]([NH3+])c2ccc(Cl)cc2Cl)CCCO1.,C[C@]1([C@H]([NH3+])c2ccc(Cl)cc2Cl)CCCO1,halo270227843,Remove a benzene_ring from the molecule Cc1ccc(C)c(CSc2ncc(CO)n2Cc2ccccc2)c1.,Cc1ccc(C)c(CSc2ncc(CO)n2Cc2ccccc2)c1,benzene_ring271162863,Modify the molecule NC(=O)c1cccc(CNC(=O)NCC2CCN(c3cc[nH+]cc3)CC2)c1 by removing a amide.,NC(=O)c1cccc(CNC(=O)NCC2CCN(c3cc[nH+]cc3)CC2)c1,amide272240712,Please remove a halo from the molecule CC1(C)C(C[NH2+]Cc2ccc(Br)cn2)C1(C)C.,CC1(C)C(C[NH2+]Cc2ccc(Br)cn2)C1(C)C,halo27396447,Remove a benzene_ring from the molecule Cn1c([O-])c(Sc2ccc([N+](=O)[O-])cc2)c(=O)c2ccccc21.,Cn1c([O-])c(Sc2ccc([N+](=O)[O-])cc2)c(=O)c2ccccc21,benzene_ring274220810,Please remove a benzene_ring from the molecule Cc1ccccc1[C@@H](C)NC(=O)[C@H]1CC(=O)N(CC2CC2)C1.,Cc1ccccc1[C@@H](C)NC(=O)[C@H]1CC(=O)N(CC2CC2)C1,benzene_ring275123657,Please remove a amine from the molecule O=S(=O)(Cc1ccccc1Cl)NCCc1csc(-c2ccc(F)cc2)n1.,O=S(=O)(Cc1ccccc1Cl)NCCc1csc(-c2ccc(F)cc2)n1,amine276194796,Remove a benzene_ring from the molecule COc1ccc(/C=C(/CC(=O)Nc2ccc3c(c2)OCO3)c2nc3ccccc3s2)cc1OC.,COc1ccc(/C=C(/CC(=O)Nc2ccc3c(c2)OCO3)c2nc3ccccc3s2)cc1OC,benzene_ring27774617,Please remove a amide from the molecule CCCc1ccc(-c2nc(NC(=O)c3cccc(S(C)(=O)=O)c3)sc2C)cc1.,CCCc1ccc(-c2nc(NC(=O)c3cccc(S(C)(=O)=O)c3)sc2C)cc1,amide278206997,Please remove a hydroxyl from the molecule CCC1=NN(C(=O)c2ccncc2)[C@](O)(c2ccc(Cl)cc2)C1.,CCC1=NN(C(=O)c2ccncc2)[C@](O)(c2ccc(Cl)cc2)C1,hydroxyl279215074,Please remove a benzene_ring from the molecule C[NH2+][C@H](c1ccc(OC(C)C)cc1)c1ncc[nH]1.,C[NH2+][C@H](c1ccc(OC(C)C)cc1)c1ncc[nH]1,benzene_ring28077717,Remove a amide from the molecule C[C@@H](NC(=O)NCCCC(=O)N(C)C)c1ccc(-c2ccc(F)cc2)cc1.,C[C@@H](NC(=O)NCCCC(=O)N(C)C)c1ccc(-c2ccc(F)cc2)cc1,amide281185226,Remove a halo from the molecule COc1ccc(Br)cc1CNC(=O)CCl.,COc1ccc(Br)cc1CNC(=O)CCl,halo28261811,Modify the molecule CCN(Cc1ccccn1)c1ccc(C=O)o1 by removing a aldehyde.,CCN(Cc1ccccn1)c1ccc(C=O)o1,aldehyde28375178,Remove a nitrile from the molecule CC(C)[C@@H](CO)NC(=O)[C@@H](C#N)Cc1ccccc1.,CC(C)[C@@H](CO)NC(=O)[C@@H](C#N)Cc1ccccc1,nitrile28473799,Please remove a amide from the molecule CCN(CC(=O)N1CCn2cccc2[C@H]1c1ccccc1Cl)C(=O)C1CCC1.,CCN(CC(=O)N1CCn2cccc2[C@H]1c1ccccc1Cl)C(=O)C1CCC1,amide285179620,Modify the molecule CCn1c(C(=O)NCCCc2c(C)noc2C)cc2ccccc21 by removing a amide.,CCn1c(C(=O)NCCCc2c(C)noc2C)cc2ccccc21,amide286175651,Please remove a amide from the molecule CC(C)[C@@H](CO)NC(=O)C(=O)N1C[C@H](C)Oc2ccccc21.,CC(C)[C@@H](CO)NC(=O)C(=O)N1C[C@H](C)Oc2ccccc21,amide287195373,Modify the molecule CCOc1cccc(CNC(=O)c2cccc(C#N)c2)c1 by removing a nitrile.,CCOc1cccc(CNC(=O)c2cccc(C#N)c2)c1,nitrile288104768,Remove a hydroxyl from the molecule COC(=O)Cn1cc(C[NH+]2CC[C@@H]([NH+]3CCOCC3)[C@H](O)C2)c2ccccc21.,COC(=O)Cn1cc(C[NH+]2CC[C@@H]([NH+]3CCOCC3)[C@H](O)C2)c2ccccc21,hydroxyl2893221,Modify the molecule Cc1cc2oc3c(c(=O)c2cc1Cl)[C@H](c1cccnc1)N(CCCN1CCOCC1)C3=O by removing a amide.,Cc1cc2oc3c(c(=O)c2cc1Cl)[C@H](c1cccnc1)N(CCCN1CCOCC1)C3=O,amide29063614,Please remove a nitrile from the molecule C[C@H](C#N)NC(=O)CCn1ccc2ccccc21.,C[C@H](C#N)NC(=O)CCn1ccc2ccccc21,nitrile291166229,Please remove a amide from the molecule CCO[C@H](C)C(=O)NC1CCC([NH+]2CCCCC2)CC1.,CCO[C@H](C)C(=O)NC1CCC([NH+]2CCCCC2)CC1,amide292228539,Modify the molecule COc1ccc([C@@H]2C(C#N)=C(N)O[C@H]3N=NC(C)=C23)c2ccccc12 by removing a nitrile.,COc1ccc([C@@H]2C(C#N)=C(N)O[C@H]3N=NC(C)=C23)c2ccccc12,nitrile293217312,Remove a amine from the molecule COCCn1c(-c2ccc(C(C)C)cc2)c[nH+]c1N.,COCCn1c(-c2ccc(C(C)C)cc2)c[nH+]c1N,amine294157230,Please remove a benzene_ring from the molecule Cc1cc(C)n([C@H](C)C(=O)NCc2ccccc2-c2ccc(Cn3ccnc3)cc2)n1.,Cc1cc(C)n([C@H](C)C(=O)NCc2ccccc2-c2ccc(Cn3ccnc3)cc2)n1,benzene_ring295244724,Please remove a amine from the molecule Nc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)[O-].,Nc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)[O-],amine296122638,Remove a amine from the molecule Cc1ccc(S(=O)(=O)/N=C(\[O-])Nc2nnc(C3CC3)s2)cc1.,Cc1ccc(S(=O)(=O)/N=C(\[O-])Nc2nnc(C3CC3)s2)cc1,amine29743397,Remove a halo from the molecule Cc1nn(C)c2c1nc(CCCl)n2[C@@H](C)[C@@H]1CCCO1.,Cc1nn(C)c2c1nc(CCCl)n2[C@@H](C)[C@@H]1CCCO1,halo29878415,Please remove a benzene_ring from the molecule O=C(Cc1noc(-c2ccc(-n3ccnn3)cc2)n1)NC1CCCCC1.,O=C(Cc1noc(-c2ccc(-n3ccnn3)cc2)n1)NC1CCCCC1,benzene_ring29990983,Modify the molecule CCNS(=O)(=O)[C@H]1CCN(C(=O)[C@H]2C[C@@H]2c2sccc2C)C1 by removing a amine.,CCNS(=O)(=O)[C@H]1CCN(C(=O)[C@H]2C[C@@H]2c2sccc2C)C1,amine300227520,Remove a amine from the molecule O=C(NCc1ccc(N2CCOCC2)c(F)c1)N1CC[C@H](Nc2ccccc2)C1.,O=C(NCc1ccc(N2CCOCC2)c(F)c1)N1CC[C@H](Nc2ccccc2)C1,amine301169498,Modify the molecule Cc1cccc(OC[C@@H](C)NC(=O)/C=C/C2CC2)c1 by removing a amide.,Cc1cccc(OC[C@@H](C)NC(=O)/C=C/C2CC2)c1,amide30231939,Please remove a benzene_ring from the molecule Cc1ccc(-n2c(=O)c3sccc3n(Cc3cccc(F)c3)c2=O)cc1.,Cc1ccc(-n2c(=O)c3sccc3n(Cc3cccc(F)c3)c2=O)cc1,benzene_ring303152017,Modify the molecule CC(C)c1ccccc1NC(=O)CN1C(=O)N[C@@](C)(c2ccccc2)C1=O by removing a amide.,CC(C)c1ccccc1NC(=O)CN1C(=O)N[C@@](C)(c2ccccc2)C1=O,amide30473347,Remove a benzene_ring from the molecule C[C@@H](NC[C@@H](O)c1cccc(C(F)(F)F)c1)c1cc(F)cc(F)c1.,C[C@@H](NC[C@@H](O)c1cccc(C(F)(F)F)c1)c1cc(F)cc(F)c1,benzene_ring30536435,Modify the molecule CCOC(=O)/C(=C/c1ccc2c(c1)OCO2)NC(=O)c1cccc([N+](=O)[O-])c1 by removing a amide.,CCOC(=O)/C(=C/c1ccc2c(c1)OCO2)NC(=O)c1cccc([N+](=O)[O-])c1,amide306215667,Modify the molecule O=C(NCCN1CCOCC1)c1cccc(I)c1 by removing a benzene_ring.,O=C(NCCN1CCOCC1)c1cccc(I)c1,benzene_ring307230357,Modify the molecule C[C@H]1CC[C@@H](C)CN1C(=O)Nc1cnn(-c2ccccc2S(C)(=O)=O)c1 by removing a benzene_ring.,C[C@H]1CC[C@@H](C)CN1C(=O)Nc1cnn(-c2ccccc2S(C)(=O)=O)c1,benzene_ring308246869,Remove a benzene_ring from the molecule CCc1noc(-c2ccc(C)c(NC(=O)NCc3ncnn3C)c2)n1.,CCc1noc(-c2ccc(C)c(NC(=O)NCc3ncnn3C)c2)n1,benzene_ring309142563,Modify the molecule COc1ccc(OC(=O)c2ccccc2-c2cncnc2)cc1F by removing a benzene_ring.,COc1ccc(OC(=O)c2ccccc2-c2cncnc2)cc1F,benzene_ring310121145,Modify the molecule CN1C(=O)C[C@@H](Nc2ccc(OC(F)F)cn2)[C@@H]1c1ccc(F)cc1 by removing a amide.,CN1C(=O)C[C@@H](Nc2ccc(OC(F)F)cn2)[C@@H]1c1ccc(F)cc1,amide31177881,Modify the molecule C[C@H]1CN(Cc2ccccc2NC(=O)c2ccncc2F)C[C@H](C)O1 by removing a amide.,C[C@H]1CN(Cc2ccccc2NC(=O)c2ccncc2F)C[C@H](C)O1,amide312168321,Modify the molecule CC(C)=CC[NH+]1CCC(CCC(=O)Nc2ccccc2)CC1 by removing a benzene_ring.,CC(C)=CC[NH+]1CCC(CCC(=O)Nc2ccccc2)CC1,benzene_ring313162342,Remove a amide from the molecule CNC(=O)c1c(C)cccc1[N-]S(=O)(=O)c1cc(C)c(F)cc1F.,CNC(=O)c1c(C)cccc1[N-]S(=O)(=O)c1cc(C)c(F)cc1F,amide31477977,Modify the molecule COc1cc(/C=C2/SC(=S)N([C@H]3CCS(=O)(=O)C3)C2=O)ccc1O by removing a amide.,COc1cc(/C=C2/SC(=S)N([C@H]3CCS(=O)(=O)C3)C2=O)ccc1O,amide315119212,Modify the molecule CC(=O)N1CCN(C(=O)[C@H](C)[NH+](C)Cc2nc3ccccc3n2C)CC1 by removing a amide.,CC(=O)N1CCN(C(=O)[C@H](C)[NH+](C)Cc2nc3ccccc3n2C)CC1,amide31615064,Remove a hydroxyl from the molecule COc1ccc(C(=O)N/N=C/c2cc([N+](=O)[O-])ccc2O)cc1OC.,COc1ccc(C(=O)N/N=C/c2cc([N+](=O)[O-])ccc2O)cc1OC,hydroxyl317234051,Please remove a nitrile from the molecule N#Cc1cccc(NC(=O)c2ccc(C[C@H]3CC(=O)NC3=O)cc2)c1.,N#Cc1cccc(NC(=O)c2ccc(C[C@H]3CC(=O)NC3=O)cc2)c1,nitrile31813189,Remove a amide from the molecule C[C@H](NC(=O)C(=O)Nc1ccc(F)cc1F)c1cccc(N2CCCC2=O)c1.,C[C@H](NC(=O)C(=O)Nc1ccc(F)cc1F)c1cccc(N2CCCC2=O)c1,amide319187173,Please remove a amide from the molecule CCc1nnsc1C(=O)N1CC[C@@]2(CCc3ccccc3C(=O)N2)C1.,CCc1nnsc1C(=O)N1CC[C@@]2(CCc3ccccc3C(=O)N2)C1,amide320153234,Please remove a amide from the molecule COc1ncccc1CNC(=O)c1cc(C2CC2)on1.,COc1ncccc1CNC(=O)c1cc(C2CC2)on1,amide321146635,Please remove a amine from the molecule Cc1ccc([C@H](C)NC(=O)c2csc(C#CCN)c2)s1.,Cc1ccc([C@H](C)NC(=O)c2csc(C#CCN)c2)s1,amine32239554,Modify the molecule CC[C@@H](C)N(Cc1c[nH]c2ccccc12)C(=S)Nc1cccc(C)c1 by removing a benzene_ring.,CC[C@@H](C)N(Cc1c[nH]c2ccccc12)C(=S)Nc1cccc(C)c1,benzene_ring323176346,Modify the molecule C[C@H](OCc1ccccc1)C(=O)NCC(=O)Nc1cccc2ccccc12 by removing a amide.,C[C@H](OCc1ccccc1)C(=O)NCC(=O)Nc1cccc2ccccc12,amide32458997,Modify the molecule COc1ccc(N2CCN(C(=O)[C@H](C)NC(=O)c3cc4cc(OC)ccc4n3C)CC2)cc1 by removing a benzene_ring.,COc1ccc(N2CCN(C(=O)[C@H](C)NC(=O)c3cc4cc(OC)ccc4n3C)CC2)cc1,benzene_ring325171159,Modify the molecule COc1ccc(Cc2nnc(SCC(=O)c3ccc(Br)cc3)o2)cc1 by removing a halo.,COc1ccc(Cc2nnc(SCC(=O)c3ccc(Br)cc3)o2)cc1,halo326125440,Modify the molecule Cc1cccc(CN(C)C(=O)[C@@]2(C(F)(F)F)CC[NH2+]C2)n1 by removing a halo.,Cc1cccc(CN(C)C(=O)[C@@]2(C(F)(F)F)CC[NH2+]C2)n1,halo32722164,Modify the molecule CCOC(=O)C1CCN(C(=O)c2oc3ccc(S(=O)(=O)N4C[C@H](C)C[C@@H](C)C4)cc3c2C)CC1 by removing a amide.,CCOC(=O)C1CCN(C(=O)c2oc3ccc(S(=O)(=O)N4C[C@H](C)C[C@@H](C)C4)cc3c2C)CC1,amide328199630,Modify the molecule N#CCSc1cccc(C(=O)N(CC(F)(F)F)c2ccccn2)c1 by removing a benzene_ring.,N#CCSc1cccc(C(=O)N(CC(F)(F)F)c2ccccn2)c1,benzene_ring329141203,Remove a halo from the molecule C[C@@H](Cl)c1nc2cc(Br)cnc2n1C.,C[C@@H](Cl)c1nc2cc(Br)cnc2n1C,halo33084976,Modify the molecule CSCC[C@@H](NC(=O)c1ccc2c(c1)OCO2)C(=O)N1CCC2(CC1)NCCc1[nH+]c[nH]c12 by removing a amide.,CSCC[C@@H](NC(=O)c1ccc2c(c1)OCO2)C(=O)N1CCC2(CC1)NCCc1[nH+]c[nH]c12,amide33175611,Remove a amide from the molecule C[C@H]1CCCCN1C(=O)CNc1ccc(Cl)c([N+](=O)[O-])c1.,C[C@H]1CCCCN1C(=O)CNc1ccc(Cl)c([N+](=O)[O-])c1,amide332209298,Remove a amide from the molecule Cc1c[nH+]ccc1N1CCCN(C(=O)[C@H]2Cc3ccccc3CN2)CC1.,Cc1c[nH+]ccc1N1CCCN(C(=O)[C@H]2Cc3ccccc3CN2)CC1,amide333190485,Please remove a benzene_ring from the molecule C[NH2+][C@@H](Cc1ccc(F)cc1Br)[C@H]1CN(C)CCO1.,C[NH2+][C@@H](Cc1ccc(F)cc1Br)[C@H]1CN(C)CCO1,benzene_ring334195728,Please remove a benzene_ring from the molecule COc1ccc(C)cc1-n1c(SCC2=NC(=O)[C@@H]3SC=CC3=N2)nnc1-c1cccs1.,COc1ccc(C)cc1-n1c(SCC2=NC(=O)[C@@H]3SC=CC3=N2)nnc1-c1cccs1,benzene_ring33572886,Remove a benzene_ring from the molecule COC(CNc1ccc(Br)c([N+](=O)[O-])c1)OC.,COC(CNc1ccc(Br)c([N+](=O)[O-])c1)OC,benzene_ring33692339,Please remove a benzene_ring from the molecule CC(C)C[C@@H](C[C@H](O)c1ccccc1)C(=O)[O-].,CC(C)C[C@@H](C[C@H](O)c1ccccc1)C(=O)[O-],benzene_ring33762393,Modify the molecule O=C(c1cnn(-c2ccccc2)n1)N1CCC(OCc2ccc(F)cc2)CC1 by removing a benzene_ring.,O=C(c1cnn(-c2ccccc2)n1)N1CCC(OCc2ccc(F)cc2)CC1,benzene_ring33877503,Please remove a halo from the molecule COc1ccc(CNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OC.,COc1ccc(CNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OC,halo339238856,Modify the molecule C[C@H](Oc1ccccc1)C(=O)N(C)[C@H]1CCC[C@@H]1S(C)(=O)=O by removing a benzene_ring.,C[C@H](Oc1ccccc1)C(=O)N(C)[C@H]1CCC[C@@H]1S(C)(=O)=O,benzene_ring340171059,Modify the molecule C[NH2+][C@H](c1cncc(Br)c1)c1cc(Cl)ccc1OC by removing a halo.,C[NH2+][C@H](c1cncc(Br)c1)c1cc(Cl)ccc1OC,halo34193809,Remove a amide from the molecule NC(=O)CN1CC2(CCC1=O)CC[NH+](Cc1ncccn1)CC2.,NC(=O)CN1CC2(CCC1=O)CC[NH+](Cc1ncccn1)CC2,amide34287967,Please remove a amide from the molecule Cc1n[nH]c(C)c1[C@@H]1CCC[NH+]1CC(=O)N1CCC(C(N)=O)CC1.,Cc1n[nH]c(C)c1[C@@H]1CCC[NH+]1CC(=O)N1CCC(C(N)=O)CC1,amide343210073,Please remove a amide from the molecule C[C@@H](CNC(=O)CS[C@@H]1CCS(=O)(=O)C1)N1C[C@@H](C)O[C@H](C)C1.,C[C@@H](CNC(=O)CS[C@@H]1CCS(=O)(=O)C1)N1C[C@@H](C)O[C@H](C)C1,amide34438619,Modify the molecule C#C[C@@](C)(CC)NC(=O)Cc1ccccc1 by removing a benzene_ring.,C#C[C@@](C)(CC)NC(=O)Cc1ccccc1,benzene_ring34529552,Modify the molecule Cc1nc2sc([C@@H](c3ccc(F)cc3)[NH+]3CCC4(CC3)OCCO4)c([O-])n2n1 by removing a halo.,Cc1nc2sc([C@@H](c3ccc(F)cc3)[NH+]3CCC4(CC3)OCCO4)c([O-])n2n1,halo346196915,Please remove a amide from the molecule CN1C(=O)CSc2ccc(NC(=O)N3CCC([NH+]4CCCCC4)CC3)cc21.,CN1C(=O)CSc2ccc(NC(=O)N3CCC([NH+]4CCCCC4)CC3)cc21,amide34752231,Please remove a amide from the molecule O=C(Cn1c(=O)oc2ccccc21)NCC1CCN(c2nsc3ccccc23)CC1.,O=C(Cn1c(=O)oc2ccccc21)NCC1CCN(c2nsc3ccccc23)CC1,amide34843003,Remove a amide from the molecule CCC1(CC)NC(=O)CN(C[C@]2(C)CCCO2)C1=O.,CCC1(CC)NC(=O)CN(C[C@]2(C)CCCO2)C1=O,amide349143866,Remove a benzene_ring from the molecule CNC(=O)[C@@H]1CCCCN1c1ccc(C#N)c([N+](=O)[O-])c1.,CNC(=O)[C@@H]1CCCCN1c1ccc(C#N)c([N+](=O)[O-])c1,benzene_ring350162612,Modify the molecule O=S1(=O)CC[C@]2(CC[NH2+]C[C@H]2c2ccccc2Br)C1 by removing a benzene_ring.,O=S1(=O)CC[C@]2(CC[NH2+]C[C@H]2c2ccccc2Br)C1,benzene_ring35136645,Remove a halo from the molecule CCn1ncnc1C[NH2+][C@@H](C)CCCCl.,CCn1ncnc1C[NH2+][C@@H](C)CCCCl,halo352110934,Please remove a amide from the molecule COc1ccc(Cl)cc1NC(=O)C(=O)N[C@H](C)C[NH+]1C[C@H](C)C[C@@H](C)C1.,COc1ccc(Cl)cc1NC(=O)C(=O)N[C@H](C)C[NH+]1C[C@H](C)C[C@@H](C)C1,amide353224616,Remove a amide from the molecule C=CCOc1ccccc1C[NH+](C)CC(=O)N1CCC(O)CC1.,C=CCOc1ccccc1C[NH+](C)CC(=O)N1CCC(O)CC1,amide35462163,Please remove a amide from the molecule O=C(c1cn2ccsc2n1)N1CCc2c([nH]c3ccccc23)[C@@H]1c1ccccn1.,O=C(c1cn2ccsc2n1)N1CCc2c([nH]c3ccccc23)[C@@H]1c1ccccn1,amide355171105,Modify the molecule Cc1ccc(NC(=O)Nc2nnc(SCc3ccccc3)s2)cc1 by removing a benzene_ring.,Cc1ccc(NC(=O)Nc2nnc(SCc3ccccc3)s2)cc1,benzene_ring3569738,Modify the molecule O=C(CCc1cccc(F)c1)Nc1n[nH]c2ccc([N+](=O)[O-])cc12 by removing a benzene_ring.,O=C(CCc1cccc(F)c1)Nc1n[nH]c2ccc([N+](=O)[O-])cc12,benzene_ring35758511,Remove a amine from the molecule CC(C)(C)NC(=O)CCNS(=O)(=O)c1ccc(Br)cc1.,CC(C)(C)NC(=O)CCNS(=O)(=O)c1ccc(Br)cc1,amine358237265,Remove a amide from the molecule CC(C)C[C@H](NC(=O)C1CC1)c1cccs1.,CC(C)C[C@H](NC(=O)C1CC1)c1cccs1,amide35969211,Modify the molecule CC1CCN(C(=O)[C@H]2c3ccccc3CC[NH+]2CC(=O)NCc2ccccc2Cl)CC1 by removing a benzene_ring.,CC1CCN(C(=O)[C@H]2c3ccccc3CC[NH+]2CC(=O)NCc2ccccc2Cl)CC1,benzene_ring360177937,Remove a benzene_ring from the molecule CCOc1cc(NC(=O)C(=O)N[C@H](C)[C@H]2CCCO2)ccc1C.,CCOc1cc(NC(=O)C(=O)N[C@H](C)[C@H]2CCCO2)ccc1C,benzene_ring36126896,Remove a nitro from the molecule Cc1ccc([N+](=O)[O-])cc1NC(=O)N(C)CC[NH+](C)C1CCN(C)CC1.,Cc1ccc([N+](=O)[O-])cc1NC(=O)N(C)CC[NH+](C)C1CCN(C)CC1,nitro362122348,Modify the molecule CCc1nc(NC(=O)[C@@H](C)NC(=O)c2ccccc2Cl)sc1C by removing a halo.,CCc1nc(NC(=O)[C@@H](C)NC(=O)c2ccccc2Cl)sc1C,halo363137192,Modify the molecule CC(C)[NH+]1CCCN(C(=O)CCNC(=O)c2ccc(F)cc2Cl)CC1 by removing a amide.,CC(C)[NH+]1CCCN(C(=O)CCNC(=O)c2ccc(F)cc2Cl)CC1,amide3645804,Remove a nitrile from the molecule Cc1sc(NC(=O)c2cc(Br)cs2)c(C#N)c1C.,Cc1sc(NC(=O)c2cc(Br)cs2)c(C#N)c1C,nitrile365159339,Modify the molecule O=C([O-])[C@H]1C[C@H](O)CN1C(=O)c1ccccc1O by removing a hydroxyl.,O=C([O-])[C@H]1C[C@H](O)CN1C(=O)c1ccccc1O,hydroxyl366120100,Please remove a benzene_ring from the molecule Cc1cc(C(=O)NCC(C)C)ccc1NC(=O)c1cnn(C(C)C)c1C.,Cc1cc(C(=O)NCC(C)C)ccc1NC(=O)c1cnn(C(C)C)c1C,benzene_ring36771980,Modify the molecule Cc1cccc(C)c1OC1CCN(C(=O)[C@H](C)c2cccs2)CC1 by removing a amide.,Cc1cccc(C)c1OC1CCN(C(=O)[C@H](C)c2cccs2)CC1,amide368247324,Modify the molecule C[C@H]1[C@H](C(=O)[O-])CCN1C(=O)Nc1ccc(F)cc1 by removing a benzene_ring.,C[C@H]1[C@H](C(=O)[O-])CCN1C(=O)Nc1ccc(F)cc1,benzene_ring369204098,Modify the molecule Cc1c(NC(=O)c2cccc3cc[nH]c23)cccc1C(=O)N1CCCC1 by removing a amide.,Cc1c(NC(=O)c2cccc3cc[nH]c23)cccc1C(=O)N1CCCC1,amide37030006,Modify the molecule O=C(Nc1ccccc1I)C1CCN(S(=O)(=O)c2ccccc2F)CC1 by removing a benzene_ring.,O=C(Nc1ccccc1I)C1CCN(S(=O)(=O)c2ccccc2F)CC1,benzene_ring371202346,Please remove a amide from the molecule Cc1cccc(OCC(=O)NC[C@H](c2ccc(C)o2)[NH+]2CCCCC2)c1.,Cc1cccc(OCC(=O)NC[C@H](c2ccc(C)o2)[NH+]2CCCCC2)c1,amide37230122,Please remove a nitro from the molecule O=C(C1CCCC1)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])s2)CC1.,O=C(C1CCCC1)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])s2)CC1,nitro373109745,Modify the molecule O=C(c1csnn1)N1CCO[C@@H](c2ccc(Cl)cc2)C1 by removing a amide.,O=C(c1csnn1)N1CCO[C@@H](c2ccc(Cl)cc2)C1,amide374211595,Modify the molecule Nc1cc(Cl)c([N+](=O)[O-])cc1COc1ccccc1 by removing a nitro.,Nc1cc(Cl)c([N+](=O)[O-])cc1COc1ccccc1,nitro37510193,Remove a halo from the molecule Cc1cccc(C(=O)NN2Cc3ccccc3C2)c1F.,Cc1cccc(C(=O)NN2Cc3ccccc3C2)c1F,halo376226112,Remove a amine from the molecule COc1ccc(O)c([C@@H](C)Nc2ccc(F)cc2[N+](=O)[O-])c1.,COc1ccc(O)c([C@@H](C)Nc2ccc(F)cc2[N+](=O)[O-])c1,amine377198343,Remove a benzene_ring from the molecule C[C@H](Oc1ccccc1Br)C(=O)N/N=C\c1cc(Cl)ccc1[N+](=O)[O-].,C[C@H](Oc1ccccc1Br)C(=O)N/N=C\c1cc(Cl)ccc1[N+](=O)[O-],benzene_ring37885850,Please remove a amide from the molecule COc1ccnc(NNC(=O)c2cccc(C#N)c2)n1.,COc1ccnc(NNC(=O)c2cccc(C#N)c2)n1,amide379139437,Remove a amide from the molecule CCOC(=O)[C@H](CC)N1CCC(C(=O)N2CCCCCC2)CC1.,CCOC(=O)[C@H](CC)N1CCC(C(=O)N2CCCCCC2)CC1,amide38029121,Modify the molecule COc1cc([C@@H]2Nc3ccccc3C3=[NH+]CCCN32)cc(OC)c1OC by removing a amine.,COc1cc([C@@H]2Nc3ccccc3C3=[NH+]CCCN32)cc(OC)c1OC,amine381168852,Remove a benzene_ring from the molecule CC[C@@H](NC(=O)N1CCN(C(=O)C2CCCCC2)CC1)c1ccc(OC)cc1.,CC[C@@H](NC(=O)N1CCN(C(=O)C2CCCCC2)CC1)c1ccc(OC)cc1,benzene_ring382171130,Remove a amide from the molecule Cc1cccc(C2=CCN(C(=O)NNC(=O)c3ccccc3)CC2)c1.,Cc1cccc(C2=CCN(C(=O)NNC(=O)c3ccccc3)CC2)c1,amide38375682,Modify the molecule CC(=O)C1=C(Nc2ccc(C)cc2)C[C@](C)(O)[C@H](C(C)=O)[C@H]1c1ccc(Cl)cc1 by removing a halo.,CC(=O)C1=C(Nc2ccc(C)cc2)C[C@](C)(O)[C@H](C(C)=O)[C@H]1c1ccc(Cl)cc1,halo384217021,Please remove a benzene_ring from the molecule O=C(NC1CCCCC1)[C@H](c1ccc(F)cc1)N(C(=O)c1cnccn1)c1ccccc1F.,O=C(NC1CCCCC1)[C@H](c1ccc(F)cc1)N(C(=O)c1cnccn1)c1ccccc1F,benzene_ring3855221,Please remove a amine from the molecule C[C@@H](CNCc1ccc(Cl)nc1)[NH+](C)Cc1ccccc1.,C[C@@H](CNCc1ccc(Cl)nc1)[NH+](C)Cc1ccccc1,amine386106216,Remove a amide from the molecule CCCCn1c(SCC(=O)N(C)C2CCCCC2)nc2cc(C)[nH]c2c1=O.,CCCCn1c(SCC(=O)N(C)C2CCCCC2)nc2cc(C)[nH]c2c1=O,amide38720529,Modify the molecule CCc1ccccc1NC(=O)N[C@H](C)C(=O)N1CCCC[C@@H]1C by removing a benzene_ring.,CCc1ccccc1NC(=O)N[C@H](C)C(=O)N1CCCC[C@@H]1C,benzene_ring38876756,Modify the molecule COc1ccc(-n2c(=S)[nH]c3ccc(C)cc32)c(C)c1 by removing a benzene_ring.,COc1ccc(-n2c(=S)[nH]c3ccc(C)cc32)c(C)c1,benzene_ring389142063,Modify the molecule COc1ccc(NC(=O)c2cccc(OC(C)=O)c2)cc1OC by removing a amide.,COc1ccc(NC(=O)c2cccc(OC(C)=O)c2)cc1OC,amide390155984,Modify the molecule Cc1cccc2c(N3CCCN(S(C)(=O)=O)CC3)c(C#N)cnc12 by removing a nitrile.,Cc1cccc2c(N3CCCN(S(C)(=O)=O)CC3)c(C#N)cnc12,nitrile391149549,Modify the molecule Cc1ccc(Cl)cc1NC(=O)C[C@H]1CSc2nc3c(cnn3-c3ccccc3)c(=O)n21 by removing a halo.,Cc1ccc(Cl)cc1NC(=O)C[C@H]1CSc2nc3c(cnn3-c3ccccc3)c(=O)n21,halo392113524,Modify the molecule Cc1ccc(CNC(=O)/C=C/c2cccc(C)c2)cc1 by removing a amide.,Cc1ccc(CNC(=O)/C=C/c2cccc(C)c2)cc1,amide39385190,Please remove a amide from the molecule Cc1cccc(CC(=O)N2CCC3(CCC(=O)N([C@H](C)C(=O)[O-])C3)CC2)c1.,Cc1cccc(CC(=O)N2CCC3(CCC(=O)N([C@H](C)C(=O)[O-])C3)CC2)c1,amide394109900,Remove a benzene_ring from the molecule Cc1ccc(C(C)C)cc1OCC(=O)N(C)[C@@H](C)c1ccc(-n2cncn2)cc1.,Cc1ccc(C(C)C)cc1OCC(=O)N(C)[C@@H](C)c1ccc(-n2cncn2)cc1,benzene_ring395131292,Modify the molecule Brc1cnc(N2CCCC2)cn1 by removing a halo.,Brc1cnc(N2CCCC2)cn1,halo39646376,Remove a amide from the molecule CCSCC[C@H](C)N(C)C(=O)c1cc(=O)c2ccccc2o1.,CCSCC[C@H](C)N(C)C(=O)c1cc(=O)c2ccccc2o1,amide39735558,Please remove a benzene_ring from the molecule Cc1ccc(C(=O)NCc2cscn2)cc1NC(=O)Nc1ccccc1.,Cc1ccc(C(=O)NCc2cscn2)cc1NC(=O)Nc1ccccc1,benzene_ring398158899,Remove a benzene_ring from the molecule O=C(Cn1ncc2c3ccccc3n(Cc3cccc(Cl)c3)c2c1=O)N1CCC2(CC1)OCCO2.,O=C(Cn1ncc2c3ccccc3n(Cc3cccc(Cl)c3)c2c1=O)N1CCC2(CC1)OCCO2,benzene_ring39987843,Modify the molecule COc1cccc([C@H]2[C@H]3[NH+]=c4ccccc4=C3CCN2Cc2cnn(C)c2C)c1 by removing a amine.,COc1cccc([C@H]2[C@H]3[NH+]=c4ccccc4=C3CCN2Cc2cnn(C)c2C)c1,amine40071760,Please remove a nitrile from the molecule CC1(C)CC(=O)C2=C(C1)OC(N)=C(C#N)[C@H]2c1ccc(C(C)(C)C)s1.,CC1(C)CC(=O)C2=C(C1)OC(N)=C(C#N)[C@H]2c1ccc(C(C)(C)C)s1,nitrile40165229,Modify the molecule O=C(Nc1cccc(-c2nnco2)c1)c1cn(-c2ccccc2)nc1-c1cccs1 by removing a benzene_ring.,O=C(Nc1cccc(-c2nnco2)c1)c1cn(-c2ccccc2)nc1-c1cccs1,benzene_ring40294796,Modify the molecule CCOc1ccc(Oc2cncc(C[NH3+])n2)cc1 by removing a benzene_ring.,CCOc1ccc(Oc2cncc(C[NH3+])n2)cc1,benzene_ring40363016,Modify the molecule O=C([O-])c1cnc(Nc2ccccc2)nc1 by removing a benzene_ring.,O=C([O-])c1cnc(Nc2ccccc2)nc1,benzene_ring404137343,Remove a amide from the molecule Cc1ncccc1C(=O)N[C@H](C(N)=S)C(C)C.,Cc1ncccc1C(=O)N[C@H](C(N)=S)C(C)C,amide405128206,Modify the molecule C[C@H]1[NH2+]CC[C@H]1C(=O)N(C)Cc1cc(C#N)ccc1F by removing a amide.,C[C@H]1[NH2+]CC[C@H]1C(=O)N(C)Cc1cc(C#N)ccc1F,amide406209129,Please remove a amide from the molecule CCc1ccc(C(=O)N2CCC[C@@H](c3cc(C(N)=O)[nH]n3)C2)o1.,CCc1ccc(C(=O)N2CCC[C@@H](c3cc(C(N)=O)[nH]n3)C2)o1,amide407198510,Modify the molecule Cc1ccc(N)c(SC[C@@H](C)CO)c1 by removing a amine.,Cc1ccc(N)c(SC[C@@H](C)CO)c1,amine408119998,Please remove a halo from the molecule COc1cc(NC(=O)c2ccccc2C(F)(F)F)cc(OC)c1.,COc1cc(NC(=O)c2ccccc2C(F)(F)F)cc(OC)c1,halo409178854,Please remove a halo from the molecule CO[C@@H](C)C(=O)NNc1ccccc1C(F)(F)F.,CO[C@@H](C)C(=O)NNc1ccccc1C(F)(F)F,halo410211901,Remove a benzene_ring from the molecule CC(=O)Nc1ccc(C(C)=O)cc1OCc1ccc(Br)cc1.,CC(=O)Nc1ccc(C(C)=O)cc1OCc1ccc(Br)cc1,benzene_ring411144533,Modify the molecule Cn1ccnc(NCCSCc2ccc(Cl)cc2Cl)c1=O by removing a amine.,Cn1ccnc(NCCSCc2ccc(Cl)cc2Cl)c1=O,amine41298161,Modify the molecule O=C(Nc1ccc(Nc2ccccc2)cc1)c1ccc(O)nc1 by removing a amine.,O=C(Nc1ccc(Nc2ccccc2)cc1)c1ccc(O)nc1,amine41362030,Please remove a amide from the molecule CCC(=O)Oc1ccc(C(=O)Nc2cc(Cl)ccc2C(=O)[O-])cc1.,CCC(=O)Oc1ccc(C(=O)Nc2cc(Cl)ccc2C(=O)[O-])cc1,amide414130742,Modify the molecule CCN(Cc1ccccn1)C(=O)[C@H]1C[NH2+]C[C@@H]1C by removing a amide.,CCN(Cc1ccccn1)C(=O)[C@H]1C[NH2+]C[C@@H]1C,amide415120102,Please remove a amide from the molecule CC[C@H](C)NC(=O)c1ccc(Cl)c(S(=O)(=O)N2CCN(C)CC2)c1.,CC[C@H](C)NC(=O)c1ccc(Cl)c(S(=O)(=O)N2CCN(C)CC2)c1,amide416141485,Modify the molecule Cc1cccc(OC(=O)CCCN2C(=O)NC3(CCCC3)C2=O)c1 by removing a benzene_ring.,Cc1cccc(OC(=O)CCCN2C(=O)NC3(CCCC3)C2=O)c1,benzene_ring417214155,Please remove a amide from the molecule N#CCc1ccccc1C(=O)OCC(=O)NCc1cccs1.,N#CCc1ccccc1C(=O)OCC(=O)NCc1cccs1,amide418210127,Please remove a benzene_ring from the molecule CCc1cccc(C(=O)N2CCN(Cc3cccc([N+](=O)[O-])c3)CC2)c1O.,CCc1cccc(C(=O)N2CCN(Cc3cccc([N+](=O)[O-])c3)CC2)c1O,benzene_ring419143704,Remove a benzene_ring from the molecule C[C@H]1CCCCN1S(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(F)cc2)cc1.,C[C@H]1CCCCN1S(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(F)cc2)cc1,benzene_ring42075330,Please remove a halo from the molecule COc1cc(OC)cc(-c2nnc(SCc3ccc(F)cc3)o2)c1.,COc1cc(OC)cc(-c2nnc(SCc3ccc(F)cc3)o2)c1,halo42112008,Please remove a hydroxyl from the molecule Cc1ccccc1C(=O)NCCC(=O)NC[C@H](O)c1ccc(Cl)cc1.,Cc1ccccc1C(=O)NCCC(=O)NC[C@H](O)c1ccc(Cl)cc1,hydroxyl422182920,Remove a amide from the molecule CN(Cc1csc2ccccc12)C(=O)NCc1cccc(C(N)=O)c1.,CN(Cc1csc2ccccc12)C(=O)NCc1cccc(C(N)=O)c1,amide423168029,Remove a halo from the molecule COc1cc(C(=O)Nc2nc3c(C)cccc3s2)cc(Cl)c1OC.,COc1cc(C(=O)Nc2nc3c(C)cccc3s2)cc(Cl)c1OC,halo424132630,Remove a benzene_ring from the molecule C[NH+]1[C@H]2CC[C@@H]1CN(C(=O)NCCCS(=O)(=O)c1ccccc1)CC2.,C[NH+]1[C@H]2CC[C@@H]1CN(C(=O)NCCCS(=O)(=O)c1ccccc1)CC2,benzene_ring425247824,Modify the molecule CCNC(=O)C1CC[NH+]([C@@H](C)c2cccc(C)c2)CC1 by removing a amide.,CCNC(=O)C1CC[NH+]([C@@H](C)c2cccc(C)c2)CC1,amide426176970,Modify the molecule Cn1ncc2c1CCC[C@H]2N[C@H]1C[NH+]2CCC1CC2 by removing a amine.,Cn1ncc2c1CCC[C@H]2N[C@H]1C[NH+]2CCC1CC2,amine427151547,Modify the molecule Cc1cnoc1-c1ccc(C#N)cc1 by removing a nitrile.,Cc1cnoc1-c1ccc(C#N)cc1,nitrile42852539,Remove a hydroxyl from the molecule Cc1c(C[NH2+][C@H]2CCC[C@@H](O)C2)cnn1C.,Cc1c(C[NH2+][C@H]2CCC[C@@H](O)C2)cnn1C,hydroxyl429230914,Please remove a benzene_ring from the molecule Cc1noc(C)c1[C@@H](C)CN[C@H](C)c1ccc(C(C)C)cc1.,Cc1noc(C)c1[C@@H](C)CN[C@H](C)c1ccc(C(C)C)cc1,benzene_ring43058395,Please remove a halo from the molecule CCOC(=O)c1cccc(NC(=O)c2ccccc2F)c1.,CCOC(=O)c1cccc(NC(=O)c2ccccc2F)c1,halo431144220,Remove a amide from the molecule Cc1ccc(OCn2ccc(C(=O)N[C@@H](C)c3cn(C)nc3C)n2)c(C)c1.,Cc1ccc(OCn2ccc(C(=O)N[C@@H](C)c3cn(C)nc3C)n2)c(C)c1,amide432109067,Please remove a amide from the molecule CCCC(=O)N1CCc2[nH]nc(C(=O)NCc3ccc4c(c3)OCO4)c2C1.,CCCC(=O)N1CCc2[nH]nc(C(=O)NCc3ccc4c(c3)OCO4)c2C1,amide433129929,Please remove a benzene_ring from the molecule Cc1ccc(C2=[NH+]CCN2)c(O)c1.,Cc1ccc(C2=[NH+]CCN2)c(O)c1,benzene_ring43445255,Please remove a halo from the molecule CN(C)C(=O)NCC(=O)N1CCc2[nH]nc(-c3ccc(F)c(F)c3)c2C1.,CN(C)C(=O)NCC(=O)N1CCc2[nH]nc(-c3ccc(F)c(F)c3)c2C1,halo43540026,Please remove a benzene_ring from the molecule Cc1ccc(C(=O)CN2C(=O)N[C@@](C)(c3ccccc3Br)C2=O)cc1.,Cc1ccc(C(=O)CN2C(=O)N[C@@](C)(c3ccccc3Br)C2=O)cc1,benzene_ring436240715,Modify the molecule CCCOCC(=O)N[C@H](C)c1cnn(-c2cccc3ccccc23)c1C by removing a amide.,CCCOCC(=O)N[C@H](C)c1cnn(-c2cccc3ccccc23)c1C,amide4378321,Remove a amide from the molecule CC(C)(C)N1C[C@H](NC(=O)NC[C@@](C)(O)c2ccccc2)CC1=O.,CC(C)(C)N1C[C@H](NC(=O)NC[C@@](C)(O)c2ccccc2)CC1=O,amide43889151,Modify the molecule O=C(NC[C@H](O)c1ccco1)c1ccc(SC(F)F)cc1 by removing a halo.,O=C(NC[C@H](O)c1ccco1)c1ccc(SC(F)F)cc1,halo43988437,Please remove a benzene_ring from the molecule CC1=NN(c2ccccc2)C(=O)/C1=C\c1ccc(OCC(=O)[O-])cc1.,CC1=NN(c2ccccc2)C(=O)/C1=C\c1ccc(OCC(=O)[O-])cc1,benzene_ring44059307,Remove a halo from the molecule CCOc1ccccc1N1CC[NH+](Cc2nnsc2Cl)CC1.,CCOc1ccccc1N1CC[NH+](Cc2nnsc2Cl)CC1,halo441141912,Remove a halo from the molecule C[C@@H](CCc1ccco1)[NH2+]Cc1ncccc1F.,C[C@@H](CCc1ccco1)[NH2+]Cc1ncccc1F,halo44282951,Please remove a halo from the molecule NC(=O)CN1CCN(C(=O)C[C@@H](O)c2ccc(Cl)cc2)CC1.,NC(=O)CN1CCN(C(=O)C[C@@H](O)c2ccc(Cl)cc2)CC1,halo443180213,Modify the molecule C[C@@H](NC(=O)Nc1cccc2c1OCCO2)c1ccc(OC(F)F)cc1 by removing a benzene_ring.,C[C@@H](NC(=O)Nc1cccc2c1OCCO2)c1ccc(OC(F)F)cc1,benzene_ring444216873,Modify the molecule COc1ccccc1C(=O)N1CCN(C(=O)Cc2c(C)noc2C)CC1 by removing a benzene_ring.,COc1ccccc1C(=O)N1CCN(C(=O)Cc2c(C)noc2C)CC1,benzene_ring44595366,Remove a amide from the molecule COCCC(=O)N1CCN(S(=O)(=O)c2cnc(-c3ccccn3)nc2C)CC1.,COCCC(=O)N1CCN(S(=O)(=O)c2cnc(-c3ccccn3)nc2C)CC1,amide4466764,Remove a benzene_ring from the molecule CCOc1ccc(O[C@H](C)C(=O)Nc2ccc(C)cc2Br)cc1.,CCOc1ccc(O[C@H](C)C(=O)Nc2ccc(C)cc2Br)cc1,benzene_ring447100925,Modify the molecule COc1ccc(-n2c(C)nc3nc([NH+]4CCCC4)nc([O-])c3c2=S)cc1 by removing a benzene_ring.,COc1ccc(-n2c(C)nc3nc([NH+]4CCCC4)nc([O-])c3c2=S)cc1,benzene_ring44898314,Please remove a hydroxyl from the molecule CCS[C@@H]1CCC[C@](CO)([NH2+]C(C)C)C1.,CCS[C@@H]1CCC[C@](CO)([NH2+]C(C)C)C1,hydroxyl44976499,Please remove a benzene_ring from the molecule COc1ccc2c(c1)CCCN2CC(=O)NCC(=O)Nc1ccc(F)c(F)c1.,COc1ccc2c(c1)CCCN2CC(=O)NCC(=O)Nc1ccc(F)c(F)c1,benzene_ring450220252,Remove a amide from the molecule CC(C)CCN1C[C@@H](C(=O)Nc2ccc3cc[nH]c3c2)CC1=O.,CC(C)CCN1C[C@@H](C(=O)Nc2ccc3cc[nH]c3c2)CC1=O,amide4514828,Remove a nitrile from the molecule CCOc1ccccc1[C@H]1C(C#N)=C(SCC(=O)Nc2cc(C)ccc2C)N=C2CCCC(=O)[C@@H]21.,CCOc1ccccc1[C@H]1C(C#N)=C(SCC(=O)Nc2cc(C)ccc2C)N=C2CCCC(=O)[C@@H]21,nitrile45234195,Modify the molecule CCn1ccnc1SCC(=O)N1CCO[C@@H]2CCCC[C@H]21 by removing a amide.,CCn1ccnc1SCC(=O)N1CCO[C@@H]2CCCC[C@H]21,amide453221792,Modify the molecule N#Cc1c(NC(=O)CCCc2nc(-c3ccccc3)no2)sc2c1CCCC2 by removing a benzene_ring.,N#Cc1c(NC(=O)CCCc2nc(-c3ccccc3)no2)sc2c1CCCC2,benzene_ring454207389,Remove a benzene_ring from the molecule CCc1ccc(NC(=O)N2CCOc3ccccc32)cc1.,CCc1ccc(NC(=O)N2CCOc3ccccc32)cc1,benzene_ring455244295,Modify the molecule O=C(Nc1cc(F)ccc1Cl)[C@@H]1CCCN1C(=O)c1cccs1 by removing a amide.,O=C(Nc1cc(F)ccc1Cl)[C@@H]1CCCN1C(=O)c1cccs1,amide456166534,Remove a halo from the molecule O=C(C[NH2+]CCc1ccccc1)Nc1ccc(Cl)c(Cl)c1.,O=C(C[NH2+]CCc1ccccc1)Nc1ccc(Cl)c(Cl)c1,halo45725242,Modify the molecule O=C(NC(=S)Nc1ccccn1)c1ccc(Cl)cc1 by removing a halo.,O=C(NC(=S)Nc1ccccn1)c1ccc(Cl)cc1,halo458133764,Remove a hydroxyl from the molecule O=C1/C(=C/c2ccc3ccccc3n2)Oc2cc(O)ccc21.,O=C1/C(=C/c2ccc3ccccc3n2)Oc2cc(O)ccc21,hydroxyl45958584,Modify the molecule CC[NH2+]Cc1cnn(-c2cccc(Br)c2)c1C1CC1 by removing a benzene_ring.,CC[NH2+]Cc1cnn(-c2cccc(Br)c2)c1C1CC1,benzene_ring46082880,Remove a hydroxyl from the molecule CC[C@](C)(C[NH3+])[C@H](O)CCc1ccccc1.,CC[C@](C)(C[NH3+])[C@H](O)CCc1ccccc1,hydroxyl461133652,Please remove a amide from the molecule CC(=O)NCCNC(=O)/C=C/c1cc(C(F)(F)F)ccc1Cl.,CC(=O)NCCNC(=O)/C=C/c1cc(C(F)(F)F)ccc1Cl,amide462211492,Please remove a benzene_ring from the molecule C[C@H]1C[C@@H]1C(=O)NC[C@@H](C)Sc1ccc(Br)cc1.,C[C@H]1C[C@@H]1C(=O)NC[C@@H](C)Sc1ccc(Br)cc1,benzene_ring46352436,Remove a benzene_ring from the molecule O=C(Cc1cccc(F)c1F)c1cc(Cl)ccc1F.,O=C(Cc1cccc(F)c1F)c1cc(Cl)ccc1F,benzene_ring464111231,Remove a amide from the molecule CC(=O)N[C@H]1[C@H](OC2=C[C@H]3OC(=O)C=C(C)[C@H]3C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O.,CC(=O)N[C@H]1[C@H](OC2=C[C@H]3OC(=O)C=C(C)[C@H]3C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O,amide46510166,Please remove a amide from the molecule COc1nn(C)cc1C(=O)NCC1CCN(C(=O)c2cccnc2SC)CC1.,COc1nn(C)cc1C(=O)NCC1CCN(C(=O)c2cccnc2SC)CC1,amide46684888,Remove a halo from the molecule Cc1ccc(Cl)cc1NC(=O)CNc1ccc(S(=O)(=O)N2CCCCC2)cc1.,Cc1ccc(Cl)cc1NC(=O)CNc1ccc(S(=O)(=O)N2CCCCC2)cc1,halo467186235,Modify the molecule O=C1NCC=Cc2c1[nH]c(Br)c2Br by removing a halo.,O=C1NCC=Cc2c1[nH]c(Br)c2Br,halo468112751,Remove a benzene_ring from the molecule COc1ccc(F)cc1C(=O)COC(=O)c1csc(-c2ccc(C)cc2)n1.,COc1ccc(F)cc1C(=O)COC(=O)c1csc(-c2ccc(C)cc2)n1,benzene_ring46948767,Remove a amine from the molecule O=C(Nc1cc(Cl)ccc1O)c1cc2n(n1)[C@@H](C(F)(F)F)C[C@H](c1ccc3c(c1)OCO3)N2.,O=C(Nc1cc(Cl)ccc1O)c1cc2n(n1)[C@@H](C(F)(F)F)C[C@H](c1ccc3c(c1)OCO3)N2,amine470218466,Please remove a benzene_ring from the molecule COc1ccc([C@H]2[C@@H]3SC(=O)N=C3S[C@@H](C(=O)[O-])[C@H]2C(=O)c2ccc3c(c2)CCCC3)cc1.,COc1ccc([C@H]2[C@@H]3SC(=O)N=C3S[C@@H](C(=O)[O-])[C@H]2C(=O)c2ccc3c(c2)CCCC3)cc1,benzene_ring471110805,Modify the molecule CCC(=O)Nc1ccc(NC(=O)NCCc2cccs2)cc1C by removing a amide.,CCC(=O)Nc1ccc(NC(=O)NCCc2cccs2)cc1C,amide472233134,Modify the molecule COc1ccc(N2C(=O)/C(=C/c3cn(-c4ccccc4)nc3-c3ccccc3)SC2=S)cc1 by removing a amide.,COc1ccc(N2C(=O)/C(=C/c3cn(-c4ccccc4)nc3-c3ccccc3)SC2=S)cc1,amide47311003,Remove a benzene_ring from the molecule COc1ccc(CN2CC[NH+](Cn3nc(C4CC4)n(C)c3=S)CC2)cc1.,COc1ccc(CN2CC[NH+](Cn3nc(C4CC4)n(C)c3=S)CC2)cc1,benzene_ring474115435,Please remove a amide from the molecule CCOC(=O)[C@H]1CCCN(C(=O)c2ccc(C)nc2)C1.,CCOC(=O)[C@H]1CCCN(C(=O)c2ccc(C)nc2)C1,amide475219959,Modify the molecule C#CCOc1ccc(/C=C2/C(=O)NN(c3cc(Cl)cc(Cl)c3)C2=O)cc1OCC by removing a amide.,C#CCOc1ccc(/C=C2/C(=O)NN(c3cc(Cl)cc(Cl)c3)C2=O)cc1OCC,amide476172486,Modify the molecule O=C1CC[C@@H](Cn2c(CCCl)nc3cccnc32)N1 by removing a halo.,O=C1CC[C@@H](Cn2c(CCCl)nc3cccnc32)N1,halo47738296,Remove a amide from the molecule COc1ccc2cc(C(=O)NCc3cccc(NC(=O)N4CCCC4)c3)[nH]c2c1.,COc1ccc2cc(C(=O)NCc3cccc(NC(=O)N4CCCC4)c3)[nH]c2c1,amide478119671,Modify the molecule C[C@@H]1C[C@@H]1n1c(CCCl)nc2cc(Br)cnc21 by removing a halo.,C[C@@H]1C[C@@H]1n1c(CCCl)nc2cc(Br)cnc21,halo479153105,Modify the molecule N#Cc1cccc(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)c1 by removing a benzene_ring.,N#Cc1cccc(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)c1,benzene_ring48088532,Modify the molecule CCn1cc(C[NH+](CC2CC2)[C@H](C)c2ccccc2)cn1 by removing a benzene_ring.,CCn1cc(C[NH+](CC2CC2)[C@H](C)c2ccccc2)cn1,benzene_ring481224456,Modify the molecule CC[NH+]1CCCN(C(=O)[C@@H]2CCC(=O)N(c3ccc(C)c(C)c3)C2)CC1 by removing a benzene_ring.,CC[NH+]1CCCN(C(=O)[C@@H]2CCC(=O)N(c3ccc(C)c(C)c3)C2)CC1,benzene_ring48267007,Remove a benzene_ring from the molecule CC[C@H](C)N(C)C(=O)Nc1ccc(N(C)C)cc1.,CC[C@H](C)N(C)C(=O)Nc1ccc(N(C)C)cc1,benzene_ring483175371,Modify the molecule COC(=O)[C@H](O)C1CC[NH+](CC2=Cc3ccccc3OC2)CC1 by removing a hydroxyl.,COC(=O)[C@H](O)C1CC[NH+](CC2=Cc3ccccc3OC2)CC1,hydroxyl484146953,Please remove a benzene_ring from the molecule Cc1csc(S[C@H](C)C(=O)NC(c2ccccc2)c2ccccc2)n1.,Cc1csc(S[C@H](C)C(=O)NC(c2ccccc2)c2ccccc2)n1,benzene_ring48598587,Remove a amide from the molecule CNC(=O)c1sc2ccccc2c1[C@H]1CCN(C(=O)c2cccc(N(C)C)c2)C1.,CNC(=O)c1sc2ccccc2c1[C@H]1CCN(C(=O)c2cccc(N(C)C)c2)C1,amide486230603,Remove a amide from the molecule Cc1ccc(-n2c(SCC(=O)N3CCC(C)CC3)nc3[nH]nc(C)c3c2=[NH2+])cc1.,Cc1ccc(-n2c(SCC(=O)N3CCC(C)CC3)nc3[nH]nc(C)c3c2=[NH2+])cc1,amide487225188,Please remove a amide from the molecule CN(C(=O)c1ccccc1NC(=O)/C=C/c1ccc(Cl)cc1)C1CCCCC1.,CN(C(=O)c1ccccc1NC(=O)/C=C/c1ccc(Cl)cc1)C1CCCCC1,amide48863245,Modify the molecule Cc1ccc(C(C)(C)C)cc1[S@@](=O)Cc1cn2ccccc2n1 by removing a benzene_ring.,Cc1ccc(C(C)(C)C)cc1[S@@](=O)Cc1cn2ccccc2n1,benzene_ring489226737,Modify the molecule CN(C)C(=O)[C@@H](OC(=O)CCn1nnc2ccccc2c1=O)c1ccccc1 by removing a benzene_ring.,CN(C)C(=O)[C@@H](OC(=O)CCn1nnc2ccccc2c1=O)c1ccccc1,benzene_ring490126672,Remove a amide from the molecule CC(C)NC(=O)C[C@H](C)NC(=O)N(C)[C@@H]1CCc2ccccc2C1.,CC(C)NC(=O)C[C@H](C)NC(=O)N(C)[C@@H]1CCc2ccccc2C1,amide491141863,Please remove a amide from the molecule CCCN1C(=O)C([O-])=C(C(C)=O)[C@H]1c1ccccc1.,CCCN1C(=O)C([O-])=C(C(C)=O)[C@H]1c1ccccc1,amide49214303,Remove a benzene_ring from the molecule COCC(=O)N[C@H](C)c1nc2ccccc2n1Cc1ccc(F)cc1.,COCC(=O)N[C@H](C)c1nc2ccccc2n1Cc1ccc(F)cc1,benzene_ring49352898,Remove a hydroxyl from the molecule CCC[NH+]1CCN([C@H]2CC[C@@](CO)([NH2+]C(C)C)C2)CC1.,CCC[NH+]1CCN([C@H]2CC[C@@](CO)([NH2+]C(C)C)C2)CC1,hydroxyl494162454,Modify the molecule COc1cccc(-n2cc(C(=O)[O-])c3c2[C@H](c2cc(OC)c(OC)c(OC)c2)CC(=O)N3)c1 by removing a benzene_ring.,COc1cccc(-n2cc(C(=O)[O-])c3c2[C@H](c2cc(OC)c(OC)c(OC)c2)CC(=O)N3)c1,benzene_ring495175837,Remove a benzene_ring from the molecule [NH3+][C@H](CC[C@H]1CCOC2(CCOCC2)C1)c1ccccc1.,[NH3+][C@H](CC[C@H]1CCOC2(CCOCC2)C1)c1ccccc1,benzene_ring496147952,Please remove a nitrile from the molecule Cc1cc(SCC(=O)NC2(C#N)CCCCC2)nc2ccccc12.,Cc1cc(SCC(=O)NC2(C#N)CCCCC2)nc2ccccc12,nitrile49715006,Please remove a benzene_ring from the molecule CC(C)Cc1nnc([C@@H](C)[NH+]2CCC(c3ccc(F)cc3)CC2)o1.,CC(C)Cc1nnc([C@@H](C)[NH+]2CCC(c3ccc(F)cc3)CC2)o1,benzene_ring498198802,Please remove a amide from the molecule COC(=O)[C@H](CC(C)C)NC(=O)[C@H]1CSC(C)(C)N1C=O.,COC(=O)[C@H](CC(C)C)NC(=O)[C@H]1CSC(C)(C)N1C=O,amide499148945,Modify the molecule Cc1sc2nc(C[NH+]3CCN(CC(=O)NCCC4=CCCCC4)CC3)[nH]c(=O)c2c1C by removing a amide.,Cc1sc2nc(C[NH+]3CCN(CC(=O)NCCC4=CCCCC4)CC3)[nH]c(=O)c2c1C,amide50050029,Remove a hydroxyl from the molecule C[NH+]1CCC(O)([C@@H]2CCOC3(CCC3)C2)CC1.,C[NH+]1CCC(O)([C@@H]2CCOC3(CCC3)C2)CC1,hydroxyl50140734,Modify the molecule Fc1cc(Br)ccc1NCc1cccnc1Cl by removing a halo.,Fc1cc(Br)ccc1NCc1cccnc1Cl,halo502143151,Modify the molecule CCN(C(=O)Cc1cc(C)[nH]n1)[C@@H]1CC[NH+]([C@@H](C)c2ccccc2)C1 by removing a amide.,CCN(C(=O)Cc1cc(C)[nH]n1)[C@@H]1CC[NH+]([C@@H](C)c2ccccc2)C1,amide503143022,Please remove a amine from the molecule N#C[C@H]1CNCCN1C(=O)c1cccc(O)c1.,N#C[C@H]1CNCCN1C(=O)c1cccc(O)c1,amine504176997,Remove a amide from the molecule C[C@H]1CC(C(=O)NCc2ccc(CN3CCc4ccccc43)cc2)C[C@H](C)O1.,C[C@H]1CC(C(=O)NCc2ccc(CN3CCc4ccccc43)cc2)C[C@H](C)O1,amide505212068,Modify the molecule CCc1nnc(-c2ccc(NC(=O)C(=O)N[C@@H]3CCCC[C@@H]3C)cc2)o1 by removing a benzene_ring.,CCc1nnc(-c2ccc(NC(=O)C(=O)N[C@@H]3CCCC[C@@H]3C)cc2)o1,benzene_ring506133191,Remove a benzene_ring from the molecule CCc1nnc(NC(=O)N[C@@H](C)c2ccc(F)c(F)c2)s1.,CCc1nnc(NC(=O)N[C@@H](C)c2ccc(F)c(F)c2)s1,benzene_ring507138534,Remove a halo from the molecule CCCCNC(=O)N[C@H]1CCCN(c2ccc(OC(F)F)cc2)C1=O.,CCCCNC(=O)N[C@H]1CCCN(c2ccc(OC(F)F)cc2)C1=O,halo508167272,Please remove a amine from the molecule Cc1nsc(Nc2ccc(F)c(F)c2)c1C#N.,Cc1nsc(Nc2ccc(F)c(F)c2)c1C#N,amine509131552,Modify the molecule CC(=O)N(C)c1ccccn1 by removing a amide.,CC(=O)N(C)c1ccccn1,amide510219404,Remove a benzene_ring from the molecule C[C@@H](c1ccccn1)N(C)C(=O)Nc1cccc(C2SCCS2)c1.,C[C@@H](c1ccccn1)N(C)C(=O)Nc1cccc(C2SCCS2)c1,benzene_ring511616,Please remove a hydroxyl from the molecule CCOc1cc(CO)cc(Br)c1OCc1ccccc1F.,CCOc1cc(CO)cc(Br)c1OCc1ccccc1F,hydroxyl512167861,Remove a amide from the molecule Cc1ccsc1/C=N/NC(=O)/C(=C\c1ccc2c(c1)OCO2)NC(=O)c1ccccc1.,Cc1ccsc1/C=N/NC(=O)/C(=C\c1ccc2c(c1)OCO2)NC(=O)c1ccccc1,amide513216704,Remove a halo from the molecule CSc1cccc(NC(=O)N2CCN(c3ccccc3Cl)CC2)c1.,CSc1cccc(NC(=O)N2CCN(c3ccccc3Cl)CC2)c1,halo5142366,Please remove a halo from the molecule Cc1ccc(O)c(NS(=O)(=O)c2cc(F)c(F)c(F)c2)c1.,Cc1ccc(O)c(NS(=O)(=O)c2cc(F)c(F)c(F)c2)c1,halo51556176,Remove a amide from the molecule CCOC(=O)c1nn(-c2ccccc2C)c(=O)cc1NC(=O)c1ccc(Cl)cc1.,CCOC(=O)c1nn(-c2ccccc2C)c(=O)cc1NC(=O)c1ccc(Cl)cc1,amide51638353,Modify the molecule O[C@@H](CN1CCc2sccc2C1)c1ccccc1 by removing a hydroxyl.,O[C@@H](CN1CCc2sccc2C1)c1ccccc1,hydroxyl51753681,Remove a amide from the molecule O=C(Cn1c(=O)sc2cc(S(=O)(=O)N3CCCC3)ccc21)NC1CCCCC1.,O=C(Cn1c(=O)sc2cc(S(=O)(=O)N3CCCC3)ccc21)NC1CCCCC1,amide518220132,Modify the molecule CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2ccc(/C=C\C(=O)c3ccccc3)cc2)c1 by removing a amide.,CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2ccc(/C=C\C(=O)c3ccccc3)cc2)c1,amide519103486,Please remove a amide from the molecule COc1ccc(C(=O)N[C@@H](C(=O)Nc2ncc(C)s2)C(C)C)cc1.,COc1ccc(C(=O)N[C@@H](C(=O)Nc2ncc(C)s2)C(C)C)cc1,amide520123881,Remove a benzene_ring from the molecule CN(c1ccccn1)S(=O)(=O)c1ccc(F)cc1F.,CN(c1ccccn1)S(=O)(=O)c1ccc(F)cc1F,benzene_ring521205585,Please remove a amine from the molecule C/[NH+]=C(/NCc1noc(C)n1)N1CCc2cc(OC)c(OC)cc2C1.,C/[NH+]=C(/NCc1noc(C)n1)N1CCc2cc(OC)c(OC)cc2C1,amine522220130,Please remove a amide from the molecule COc1ccc(CC[NH+](C)[C@H]2CCCN(C(=O)c3ccncc3)C2)cc1OC.,COc1ccc(CC[NH+](C)[C@H]2CCCN(C(=O)c3ccncc3)C2)cc1OC,amide523129196,Remove a amide from the molecule CNC(=O)c1ccccc1NC(=O)[C@H]1CC[NH2+][C@H]1C.,CNC(=O)c1ccccc1NC(=O)[C@H]1CC[NH2+][C@H]1C,amide524107596,Remove a amide from the molecule O=C(NCc1coc(-c2ccccc2)n1)c1cnc([C@H]2CCCO2)s1.,O=C(NCc1coc(-c2ccccc2)n1)c1cnc([C@H]2CCCO2)s1,amide525216061,Modify the molecule CC[S@@](=O)[C@@H]1CCCC[C@@H]1NC(=O)Nc1ccccc1N1CCCCC1 by removing a benzene_ring.,CC[S@@](=O)[C@@H]1CCCC[C@@H]1NC(=O)Nc1ccccc1N1CCCCC1,benzene_ring526149190,Remove a nitro from the molecule Cc1cccc(Nc2ncnc(N3CCCC[C@H]3C)c2[N+](=O)[O-])c1.,Cc1cccc(Nc2ncnc(N3CCCC[C@H]3C)c2[N+](=O)[O-])c1,nitro527240059,Modify the molecule N#C[C@@H]1OC(=O)c2cccc(F)c21 by removing a halo.,N#C[C@@H]1OC(=O)c2cccc(F)c21,halo52871673,Please remove a benzene_ring from the molecule COCC[C@@H]([NH3+])c1ncc(-c2cc(F)cc(F)c2)[nH]1.,COCC[C@@H]([NH3+])c1ncc(-c2cc(F)cc(F)c2)[nH]1,benzene_ring52911067,Please remove a amide from the molecule Cc1cc(C)cc(NC(=O)C(=O)NCc2ncc(C)s2)c1.,Cc1cc(C)cc(NC(=O)C(=O)NCc2ncc(C)s2)c1,amide53083046,Please remove a benzene_ring from the molecule CC[C@@H](NC(=O)NCc1scnc1C)C(C)(C)c1ccccc1.,CC[C@@H](NC(=O)NCc1scnc1C)C(C)(C)c1ccccc1,benzene_ring531219496,Please remove a amine from the molecule O=c1c(N[C@H]2CCC[NH2+]C2)nccn1-c1ccccc1.,O=c1c(N[C@H]2CCC[NH2+]C2)nccn1-c1ccccc1,amine532189280,Modify the molecule COc1ccccc1C[NH2+]CC[C@H]1CCCO1 by removing a benzene_ring.,COc1ccccc1C[NH2+]CC[C@H]1CCCO1,benzene_ring533234047,Please remove a amide from the molecule C[C@H]1CC[C@@H](C)C[NH+]1CC(=O)NC1CCCC1.,C[C@H]1CC[C@@H](C)C[NH+]1CC(=O)NC1CCCC1,amide534117396,Modify the molecule C[C@H](Nc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1[N+](=O)[O-])c1ccc(F)cc1F by removing a halo.,C[C@H](Nc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1[N+](=O)[O-])c1ccc(F)cc1F,halo53516515,Remove a amide from the molecule O=C1c2ccccc2C(=O)N1C[C@H](c1ccco1)[NH+]1CCCCC1.,O=C1c2ccccc2C(=O)N1C[C@H](c1ccco1)[NH+]1CCCCC1,amide536245161,Remove a hydroxyl from the molecule CC(C)n1c[nH+]cc1[C@H](O)[C@@H]1CCCCC[NH2+]1.,CC(C)n1c[nH+]cc1[C@H](O)[C@@H]1CCCCC[NH2+]1,hydroxyl53738155,Modify the molecule CC(C)CC(=O)N[C@@H](CC(=O)[O-])c1ccccc1Cl by removing a benzene_ring.,CC(C)CC(=O)N[C@@H](CC(=O)[O-])c1ccccc1Cl,benzene_ring538127320,Modify the molecule O=C(CSc1ncccc1Cl)N1CCC[C@H]1c1ccc2c(c1)OCCO2 by removing a halo.,O=C(CSc1ncccc1Cl)N1CCC[C@H]1c1ccc2c(c1)OCCO2,halo539160486,Remove a amine from the molecule CN(C)c1ccc([C@H]2Nc3ccc(S(=O)(=O)NCc4ccccc4)cc3[C@@H]3C=CC[C@@H]23)cc1.,CN(C)c1ccc([C@H]2Nc3ccc(S(=O)(=O)NCc4ccccc4)cc3[C@@H]3C=CC[C@@H]23)cc1,amine54027595,Remove a benzene_ring from the molecule CN1CCc2nc[nH]c2C12CC[NH+](Cc1cccc(OC3CCCC3)c1)CC2.,CN1CCc2nc[nH]c2C12CC[NH+](Cc1cccc(OC3CCCC3)c1)CC2,benzene_ring541210211,Please remove a benzene_ring from the molecule Cc1nn(C)c(C)c1CCC[NH2+][C@@H](C)c1ccccc1.,Cc1nn(C)c(C)c1CCC[NH2+][C@@H](C)c1ccccc1,benzene_ring54220033,Please remove a benzene_ring from the molecule CCCOc1ccc(OCCC2CC[NH2+]CC2)cc1.,CCCOc1ccc(OCCC2CC[NH2+]CC2)cc1,benzene_ring543164892,Modify the molecule S=C(NN=C1CCSCC1)NC1CCCCC1 by removing a amine.,S=C(NN=C1CCSCC1)NC1CCCCC1,amine544248653,Remove a benzene_ring from the molecule C[C@@H](Cc1ccc(Cl)cc1)N(C)C(=O)c1ccc2ncccc2c1.,C[C@@H](Cc1ccc(Cl)cc1)N(C)C(=O)c1ccc2ncccc2c1,benzene_ring5458369,Modify the molecule Cc1ccc(F)c(C(=O)NNC(=S)NC[C@@H]2CCCO2)c1 by removing a benzene_ring.,Cc1ccc(F)c(C(=O)NNC(=S)NC[C@@H]2CCCO2)c1,benzene_ring54649912,Remove a benzene_ring from the molecule O=C(NN=C1CCCc2ccccc21)C(O)(c1ccccc1)c1ccccc1.,O=C(NN=C1CCCc2ccccc21)C(O)(c1ccccc1)c1ccccc1,benzene_ring54799506,Please remove a amide from the molecule Cc1nn(-c2ccc(Cl)cc2)cc1C(=O)N(C)CCN1CCOCC1.,Cc1nn(-c2ccc(Cl)cc2)cc1C(=O)N(C)CCN1CCOCC1,amide54835724,Modify the molecule CC(C)CNC(=O)NC(=O)CSc1nc2ccccc2c(=O)n1C1CC1 by removing a amide.,CC(C)CNC(=O)NC(=O)CSc1nc2ccccc2c(=O)n1C1CC1,amide549134342,Modify the molecule CCOC(=O)c1nn(CC)c2c1CN(C(=O)C1=CC3=CC=N[C@@H]3C=C1)CC2 by removing a amide.,CCOC(=O)c1nn(CC)c2c1CN(C(=O)C1=CC3=CC=N[C@@H]3C=C1)CC2,amide550167887,Modify the molecule Cc1c(Cl)c(-c2ccc(N(C)S(C)(=O)=O)cc2)nc2cc3c(cc12)OCO3 by removing a halo.,Cc1c(Cl)c(-c2ccc(N(C)S(C)(=O)=O)cc2)nc2cc3c(cc12)OCO3,halo551181887,Please remove a benzene_ring from the molecule COc1cccc(-c2cc3c(N4CCc5ccccc5C4)nccn3n2)c1.,COc1cccc(-c2cc3c(N4CCc5ccccc5C4)nccn3n2)c1,benzene_ring552142223,Remove a benzene_ring from the molecule CN(Cc1ccccc1C(F)(F)F)C(=O)NCCOc1ccccc1.,CN(Cc1ccccc1C(F)(F)F)C(=O)NCCOc1ccccc1,benzene_ring553177111,Remove a amide from the molecule Cc1ccnc(NNC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)c1.,Cc1ccnc(NNC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)c1,amide554241225,Please remove a benzene_ring from the molecule N#C[C@H]1COCCN1Cc1cccc(-c2ccccn2)c1.,N#C[C@H]1COCCN1Cc1cccc(-c2ccccn2)c1,benzene_ring55590270,Please remove a amide from the molecule Cc1ccncc1[N-]S(=O)(=O)c1c[nH]c(C(=O)N2CCCC2)c1.,Cc1ccncc1[N-]S(=O)(=O)c1c[nH]c(C(=O)N2CCCC2)c1,amide556116102,Modify the molecule COC(=O)[C@H](N[C@H](C)c1cccc(-n2cccn2)c1)c1ccccc1F by removing a halo.,COC(=O)[C@H](N[C@H](C)c1cccc(-n2cccn2)c1)c1ccccc1F,halo557204012,Remove a halo from the molecule C[C@H](NC(=O)Cc1cccc(F)c1F)C1(N2CCOCC2)CCCC1.,C[C@H](NC(=O)Cc1cccc(F)c1F)C1(N2CCOCC2)CCCC1,halo55879641,Modify the molecule CC[NH+](C)CC[C@@H](c1ccccc1)[NH+]1CCOCC1 by removing a benzene_ring.,CC[NH+](C)CC[C@@H](c1ccccc1)[NH+]1CCOCC1,benzene_ring559168748,Please remove a halo from the molecule CC(C)(C)CC(=O)Nc1ccc(F)cc1F.,CC(C)(C)CC(=O)Nc1ccc(F)cc1F,halo560109135,Modify the molecule CCOC(=O)c1c(/C=C/C(=O)N(C)C2(C#N)CCC2)c(C)n(CC)c1C by removing a amide.,CCOC(=O)c1c(/C=C/C(=O)N(C)C2(C#N)CCC2)c(C)n(CC)c1C,amide56198640,Modify the molecule COc1ccc(OC)c2nc(Cl)c(CCN3C(=O)c4ccccc4C3=O)cc12 by removing a halo.,COc1ccc(OC)c2nc(Cl)c(CCN3C(=O)c4ccccc4C3=O)cc12,halo56215982,Remove a amide from the molecule CCn1c(COc2cccc3cccnc23)nnc1SCC(N)=O.,CCn1c(COc2cccc3cccnc23)nnc1SCC(N)=O,amide563238090,Modify the molecule C[C@@H](Cc1ccc(Cl)cc1Cl)C(=O)N(C)C1CCOCC1 by removing a benzene_ring.,C[C@@H](Cc1ccc(Cl)cc1Cl)C(=O)N(C)C1CCOCC1,benzene_ring564117212,Remove a amide from the molecule COCc1ccc(C(=O)N[C@H]2C[C@@](C)(OC)C2(C)C)o1.,COCc1ccc(C(=O)N[C@H]2C[C@@](C)(OC)C2(C)C)o1,amide565131407,Please remove a amide from the molecule CC[C@H]1CN(C(C)=O)CC[C@H]1CC(=O)Nc1nccs1.,CC[C@H]1CN(C(C)=O)CC[C@H]1CC(=O)Nc1nccs1,amide56669875,Modify the molecule CCN(CC)S(=O)(=O)c1ccc(NC(=O)C2CCCC2)cc1 by removing a amide.,CCN(CC)S(=O)(=O)c1ccc(NC(=O)C2CCCC2)cc1,amide56772927,Modify the molecule C[C@@H]([NH2+]CC1(CO)CCOCC1)c1cc(F)c(F)c(F)c1 by removing a halo.,C[C@@H]([NH2+]CC1(CO)CCOCC1)c1cc(F)c(F)c(F)c1,halo568204499,Modify the molecule O=C([C@H]1SCCc2sccc21)N1CCO[C@H](c2ccc(F)cc2)C1 by removing a halo.,O=C([C@H]1SCCc2sccc21)N1CCO[C@H](c2ccc(F)cc2)C1,halo56956665,Modify the molecule CC[C@H](C)[C@@H](C(=O)Nc1ccn(C)n1)N1C(=O)c2ccccc2C1=O by removing a amide.,CC[C@H](C)[C@@H](C(=O)Nc1ccn(C)n1)N1C(=O)c2ccccc2C1=O,amide57013930,Please remove a amine from the molecule CCNc1cc[nH+]c(CN2CCO[C@H]3CCCC[C@@H]32)c1.,CCNc1cc[nH+]c(CN2CCO[C@H]3CCCC[C@@H]32)c1,amine57153558,Modify the molecule COc1ccccc1NC(=O)CSc1nnc(-c2ccccn2)o1 by removing a amide.,COc1ccccc1NC(=O)CSc1nnc(-c2ccccn2)o1,amide572242568,Please remove a benzene_ring from the molecule Cc1noc(C)c1CCCNC(=O)Nc1cccc(C(C)C)c1.,Cc1noc(C)c1CCCNC(=O)Nc1cccc(C(C)C)c1,benzene_ring57310298,Remove a amide from the molecule CN(C(=O)CSc1nnc(-c2ccccc2F)o1)c1ccccc1.,CN(C(=O)CSc1nnc(-c2ccccc2F)o1)c1ccccc1,amide57459131,Remove a hydroxyl from the molecule Cc1nnc(SC[C@@H](O)CN2CCOCC2)s1.,Cc1nnc(SC[C@@H](O)CN2CCOCC2)s1,hydroxyl575243091,Remove a halo from the molecule CC(C)Cn1ncc(C(=O)N(C)[C@@H](C)Cc2ccsc2)c1C(F)F.,CC(C)Cn1ncc(C(=O)N(C)[C@@H](C)Cc2ccsc2)c1C(F)F,halo576194198,Please remove a amine from the molecule CC(=O)c1c(C)nsc1N[C@H](C)c1ccc(C)cc1.,CC(=O)c1c(C)nsc1N[C@H](C)c1ccc(C)cc1,amine57718798,Modify the molecule CCc1ccc(NC(=O)C(=O)NCC2(C)CCCC2)cc1[N+](=O)[O-] by removing a nitro.,CCc1ccc(NC(=O)C(=O)NCC2(C)CCCC2)cc1[N+](=O)[O-],nitro578135449,Please remove a amine from the molecule C/[NH+]=C(/NCCc1c[nH]c2cc(C)ccc12)NCc1cn2c(C)cccc2[nH+]1.,C/[NH+]=C(/NCCc1c[nH]c2cc(C)ccc12)NCc1cn2c(C)cccc2[nH+]1,amine579165793,Remove a halo from the molecule COC(=O)c1ccc2c(c1C)N[C@H](c1cc(Br)c(OC)c(OC)c1)[C@H]1CC=C[C@H]21.,COC(=O)c1ccc2c(c1C)N[C@H](c1cc(Br)c(OC)c(OC)c1)[C@H]1CC=C[C@H]21,halo58087066,Remove a amide from the molecule COCCN(Cc1ccco1)C(=O)c1cc2cc([N+](=O)[O-])ccc2s1.,COCCN(Cc1ccco1)C(=O)c1cc2cc([N+](=O)[O-])ccc2s1,amide581116858,Modify the molecule CCOc1ccc2[nH]c(=O)c(CNc3ccc(N4CCc5ccccc5C4)cc3)cc2c1 by removing a amine.,CCOc1ccc2[nH]c(=O)c(CNc3ccc(N4CCc5ccccc5C4)cc3)cc2c1,amine582198065,Remove a benzene_ring from the molecule CN(Cc1nnc2n1CCC2)C(=O)c1ccc(S(C)(=O)=O)cc1.,CN(Cc1nnc2n1CCC2)C(=O)c1ccc(S(C)(=O)=O)cc1,benzene_ring583147864,Please remove a halo from the molecule COc1cc(-c2noc(CN3C[C@H](C)c4ccccc43)n2)ccc1OC(F)F.,COc1cc(-c2noc(CN3C[C@H](C)c4ccccc43)n2)ccc1OC(F)F,halo58433899,Remove a amide from the molecule CCC(CC)N(CC(C)C)C(=O)[C@H]1CC[C@@H]([NH3+])C1.,CCC(CC)N(CC(C)C)C(=O)[C@H]1CC[C@@H]([NH3+])C1,amide58528564,Remove a amide from the molecule CN(CC(=O)N1N=C(c2ccc(Cl)cc2)C[C@@H]1c1ccco1)S(=O)(=O)c1cccs1.,CN(CC(=O)N1N=C(c2ccc(Cl)cc2)C[C@@H]1c1ccco1)S(=O)(=O)c1cccs1,amide58689014,Remove a amine from the molecule CN(C(=O)c1cccc(NCC(=O)NCc2ccco2)c1)c1ccccc1.,CN(C(=O)c1cccc(NCC(=O)NCc2ccco2)c1)c1ccccc1,amine5877136,Remove a hydroxyl from the molecule Cc1ccc(CC(=O)NNc2c(Cl)cccc2Cl)cc1O.,Cc1ccc(CC(=O)NNc2c(Cl)cccc2Cl)cc1O,hydroxyl588223264,Remove a thiol from the molecule SCC1(COC2CCCC2)CC1.,SCC1(COC2CCCC2)CC1,thiol589232768,Please remove a halo from the molecule COC(=O)c1cc(NC(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)cc(C(=O)OC)c1.,COC(=O)c1cc(NC(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)cc(C(=O)OC)c1,halo590234248,Modify the molecule C[NH+]1CCC[C@H](C(=O)NCc2ccc[nH]2)C1 by removing a amide.,C[NH+]1CCC[C@H](C(=O)NCc2ccc[nH]2)C1,amide59162252,Remove a benzene_ring from the molecule Cc1ccc([C@@H](C)N(C)C(=O)c2nnn[n-]2)cc1.,Cc1ccc([C@@H](C)N(C)C(=O)c2nnn[n-]2)cc1,benzene_ring59261692,Remove a amide from the molecule Cc1ccc(C)c(NC(=O)c2ncccc2OCC(F)(F)F)c1.,Cc1ccc(C)c(NC(=O)c2ncccc2OCC(F)(F)F)c1,amide593247910,Please remove a benzene_ring from the molecule COc1ccc([C@H]2CC(=O)C=C(N)C2)cc1.,COc1ccc([C@H]2CC(=O)C=C(N)C2)cc1,benzene_ring59462350,Modify the molecule COCCn1c(C)cc(/C=C(/C#N)C(=O)N[C@H]2CCCNC2=O)c1C by removing a nitrile.,COCCn1c(C)cc(/C=C(/C#N)C(=O)N[C@H]2CCCNC2=O)c1C,nitrile59599070,Modify the molecule C[C@H](Oc1ccc(Cl)cc1Cl)C(=O)NNC(=O)[C@H]1CCCC[C@H]1C(=O)[O-] by removing a halo.,C[C@H](Oc1ccc(Cl)cc1Cl)C(=O)NNC(=O)[C@H]1CCCC[C@H]1C(=O)[O-],halo596244156,Please remove a benzene_ring from the molecule Cc1cc(C2=N/C(=C\c3cc4c(cc3Cl)OCO4)C(=O)O2)ccc1Br.,Cc1cc(C2=N/C(=C\c3cc4c(cc3Cl)OCO4)C(=O)O2)ccc1Br,benzene_ring59760282,Remove a amide from the molecule O=C(Nc1nccs1)[C@H]1c2ccccc2C(=O)N(C2CCCC2)C12CCCC2.,O=C(Nc1nccs1)[C@H]1c2ccccc2C(=O)N(C2CCCC2)C12CCCC2,amide598156840,Remove a amide from the molecule O=C(NC[C@H](c1cccs1)[NH+]1CCCC1)[C@@H]1CCCN1C(=O)c1ccc(Br)cc1.,O=C(NC[C@H](c1cccs1)[NH+]1CCCC1)[C@@H]1CCCN1C(=O)c1ccc(Br)cc1,amide59999808,Please remove a amide from the molecule CCNC(=O)c1ccc([NH+]2C[C@@H](C)[C@H](C(=O)[O-])C2)[nH+]n1.,CCNC(=O)c1ccc([NH+]2C[C@@H](C)[C@H](C(=O)[O-])C2)[nH+]n1,amide60076461,Modify the molecule C[NH+]1C[C@@H](c2ccc([N+](=O)[O-])cc2)[C@@H](C(=O)c2ccc(F)cc2)[C@@]12C(=O)Nc1ccccc12 by removing a nitro.,C[NH+]1C[C@@H](c2ccc([N+](=O)[O-])cc2)[C@@H](C(=O)c2ccc(F)cc2)[C@@]12C(=O)Nc1ccccc12,nitro60188769,Remove a amide from the molecule O=C([O-])c1ccc(N2C(=O)/C(=C/C3=c4ccccc4=[NH+]C3)SC2=S)cc1O.,O=C([O-])c1ccc(N2C(=O)/C(=C/C3=c4ccccc4=[NH+]C3)SC2=S)cc1O,amide60256395,Please remove a halo from the molecule O=C(CSc1nnc(-c2cccs2)n1C1CC1)Nc1cc2[nH]c(=O)[nH]c2cc1Br.,O=C(CSc1nnc(-c2cccs2)n1C1CC1)Nc1cc2[nH]c(=O)[nH]c2cc1Br,halo603197167,Please remove a amide from the molecule O=C(NCC1CCCCC1)c1cccc(NC(=O)c2scc3c2OCO3)c1.,O=C(NCC1CCCCC1)c1cccc(NC(=O)c2scc3c2OCO3)c1,amide60471068,Please remove a hydroxyl from the molecule O=C(CCCNC(=O)c1cccs1)NC[C@@]1(O)CCSC1.,O=C(CCCNC(=O)c1cccs1)NC[C@@]1(O)CCSC1,hydroxyl60598251,Remove a halo from the molecule COc1c(Cl)cc(C(=O)OCc2nc(C)no2)cc1Cl.,COc1c(Cl)cc(C(=O)OCc2nc(C)no2)cc1Cl,halo606134822,Please remove a amide from the molecule COc1cc(CC(=O)Nc2ccc(C)cc2OC)ccc1C.,COc1cc(CC(=O)Nc2ccc(C)cc2OC)ccc1C,amide607166474,Please remove a nitrile from the molecule N#CCCCSc1nnc(-c2ccccc2)n1-c1ccccc1.,N#CCCCSc1nnc(-c2ccccc2)n1-c1ccccc1,nitrile60845146,Remove a hydroxyl from the molecule COc1cccc([C@H](C)CC(=O)Nc2cnc(-c3cccc(O)c3)nc2)c1.,COc1cccc([C@H](C)CC(=O)Nc2cnc(-c3cccc(O)c3)nc2)c1,hydroxyl609123259,Modify the molecule O=C(CNC(=O)C(=O)Nc1ccccc1C[NH+]1CCCC1)NC1CC1 by removing a benzene_ring.,O=C(CNC(=O)C(=O)Nc1ccccc1C[NH+]1CCCC1)NC1CC1,benzene_ring610206350,Remove a hydroxyl from the molecule Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)N[C@H]1CCCC[C@@H]1CO.,Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)N[C@H]1CCCC[C@@H]1CO,hydroxyl611163345,Remove a amide from the molecule CC(=O)NCCc1nc2ccccc2n1CC(=O)NC[C@H]1CCCO1.,CC(=O)NCCc1nc2ccccc2n1CC(=O)NC[C@H]1CCCO1,amide612238412,Remove a nitrile from the molecule Cc1nc([O-])c(C#N)cc1C(=O)N1CCC[C@@H](c2[nH+]ccn2CC(N)=O)C1.,Cc1nc([O-])c(C#N)cc1C(=O)N1CCC[C@@H](c2[nH+]ccn2CC(N)=O)C1,nitrile613110180,Please remove a amide from the molecule CNC(=O)CC1CCN(C(=O)N[C@@H]2C[C@H]2c2ccccc2F)CC1.,CNC(=O)CC1CCN(C(=O)N[C@@H]2C[C@H]2c2ccccc2F)CC1,amide614200810,Please remove a halo from the molecule CCCNC(=O)CNC(=O)N[C@H](CC)c1ccc(C)c(F)c1.,CCCNC(=O)CNC(=O)N[C@H](CC)c1ccc(C)c(F)c1,halo615191953,Please remove a halo from the molecule Nc1ccc(S[C@H]2CCC[C@@H]2O)cc1Cl.,Nc1ccc(S[C@H]2CCC[C@@H]2O)cc1Cl,halo616121105,Remove a amide from the molecule CC(C)OCCC(=O)Nc1cccc(C(=O)NC(C)(C)C)c1.,CC(C)OCCC(=O)Nc1cccc(C(=O)NC(C)(C)C)c1,amide61752959,Remove a amide from the molecule CCc1c(C)nc(-n2nc(-c3ccco3)cc2NC(=O)COc2cccc3c2OC(C)(C)C3)nc1[O-].,CCc1c(C)nc(-n2nc(-c3ccco3)cc2NC(=O)COc2cccc3c2OC(C)(C)C3)nc1[O-],amide61862912,Remove a benzene_ring from the molecule Cc1c(NCC2(c3ccc(F)cc3)CCOCC2)cc(C#N)cc1[N+](=O)[O-].,Cc1c(NCC2(c3ccc(F)cc3)CCOCC2)cc(C#N)cc1[N+](=O)[O-],benzene_ring61990971,Remove a amide from the molecule CC1CCN(S(=O)(=O)c2ccc(-c3noc(CCC(=O)Nc4cccc(F)c4)n3)cc2)CC1.,CC1CCN(S(=O)(=O)c2ccc(-c3noc(CCC(=O)Nc4cccc(F)c4)n3)cc2)CC1,amide62046982,Remove a amide from the molecule O=C(c1ccc(-c2ccc(F)cc2)o1)N(Cc1ccccn1)C1CC1.,O=C(c1ccc(-c2ccc(F)cc2)o1)N(Cc1ccccn1)C1CC1,amide621127222,Please remove a hydroxyl from the molecule CCOCCN(C)C(=O)NCc1ccc(O)c(Br)c1.,CCOCCN(C)C(=O)NCc1ccc(O)c(Br)c1,hydroxyl622210894,Please remove a amide from the molecule O=C(NC(=S)NNC(=O)c1cccs1)c1cc2ccccc2o1.,O=C(NC(=S)NNC(=O)c1cccs1)c1cc2ccccc2o1,amide623161773,Modify the molecule O=C(NC[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)c1cnccn1 by removing a benzene_ring.,O=C(NC[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)c1cnccn1,benzene_ring624174105,Please remove a amide from the molecule O=C(Cc1ccccc1Cl)NCc1ccnc(-n2cccn2)c1.,O=C(Cc1ccccc1Cl)NCc1ccnc(-n2cccn2)c1,amide625157825,Please remove a benzene_ring from the molecule COCCc1ccc(OS(=O)(=O)c2ccc3c(c2)CCCC3)cc1.,COCCc1ccc(OS(=O)(=O)c2ccc3c(c2)CCCC3)cc1,benzene_ring626242281,Modify the molecule CC(C)(CNc1ccc(C#N)c([N+](=O)[O-])c1)S(C)(=O)=O by removing a amine.,CC(C)(CNc1ccc(C#N)c([N+](=O)[O-])c1)S(C)(=O)=O,amine627125896,Modify the molecule Cc1cc(N[C@@H](C(N)=O)c2ccccc2)ccc1C(=O)NC(C)C by removing a amide.,Cc1cc(N[C@@H](C(N)=O)c2ccccc2)ccc1C(=O)NC(C)C,amide628182665,Remove a halo from the molecule COc1ccc(CN2CC[C@H]3[C@H](CCC[NH+]3C3CC3)C2)cc1OC(F)F.,COc1ccc(CN2CC[C@H]3[C@H](CCC[NH+]3C3CC3)C2)cc1OC(F)F,halo629112270,Modify the molecule CC[NH+](CC)c1ccc([N-]S(=O)(=O)c2ccc(Cl)s2)cc1C(=O)[O-] by removing a benzene_ring.,CC[NH+](CC)c1ccc([N-]S(=O)(=O)c2ccc(Cl)s2)cc1C(=O)[O-],benzene_ring630129583,Modify the molecule C[C@H]1CCC[C@@H](NC(=O)c2ccc3c([O-])n(C)c(=S)nc3c2)[C@@H]1C by removing a amide.,C[C@H]1CCC[C@@H](NC(=O)c2ccc3c([O-])n(C)c(=S)nc3c2)[C@@H]1C,amide631167244,Modify the molecule CC(C)CN1C(=O)/C(=C2\C(=O)N(CC(=O)Nc3ccccc3Cl)c3ccccc32)SC1=S by removing a halo.,CC(C)CN1C(=O)/C(=C2\C(=O)N(CC(=O)Nc3ccccc3Cl)c3ccccc32)SC1=S,halo63213293,Please remove a halo from the molecule O=C1O[C@H](/C=N/c2ccc(C(F)(F)F)cc2)c2ccccc21.,O=C1O[C@H](/C=N/c2ccc(C(F)(F)F)cc2)c2ccccc21,halo633239955,Please remove a amine from the molecule CCOc1ccc([C@H]2C3=C(CCCC3=O)Nc3c(C(=O)Nc4ccc(F)cc4)cnn32)cc1.,CCOc1ccc([C@H]2C3=C(CCCC3=O)Nc3c(C(=O)Nc4ccc(F)cc4)cnn32)cc1,amine634162141,Modify the molecule C[C@H](Cc1ccc(Cl)cc1)N(C)C(=O)c1c[nH]c2nccc(Cl)c12 by removing a amide.,C[C@H](Cc1ccc(Cl)cc1)N(C)C(=O)c1c[nH]c2nccc(Cl)c12,amide63592841,Modify the molecule CC[C@@H](C(=O)NNC(=O)N[C@@H](c1ccccn1)C(C)C)c1ccccc1 by removing a benzene_ring.,CC[C@@H](C(=O)NNC(=O)N[C@@H](c1ccccn1)C(C)C)c1ccccc1,benzene_ring636231809,Remove a amine from the molecule CCc1cc[n+](/C(C(=O)c2ccc3c(c2)OCO3)=C(/[S-])NC2CC2)cc1.,CCc1cc[n+](/C(C(=O)c2ccc3c(c2)OCO3)=C(/[S-])NC2CC2)cc1,amine637128945,Remove a amide from the molecule O=C(c1cccc(Cl)c1)N(CCN1CCOCC1)c1nc2c(F)cc(F)cc2s1.,O=C(c1cccc(Cl)c1)N(CCN1CCOCC1)c1nc2c(F)cc(F)cc2s1,amide638175713,Please remove a amide from the molecule COCCCNC(=O)N1CCC[NH+](CC(=O)N(C)C)CC1.,COCCCNC(=O)N1CCC[NH+](CC(=O)N(C)C)CC1,amide63963829,Modify the molecule CC[C@H](C)[C@H](O)CNC(=O)C(=O)Nc1ccc(C)nc1Br by removing a amide.,CC[C@H](C)[C@H](O)CNC(=O)C(=O)Nc1ccc(C)nc1Br,amide640104165,Please remove a amide from the molecule CCO[C@H](C)c1nc(C[NH+](C)CC(N)=O)cs1.,CCO[C@H](C)c1nc(C[NH+](C)CC(N)=O)cs1,amide641102012,Please remove a amide from the molecule CCN1C(=O)Cc2ccccc2[C@H]1C(=O)NCCC1=CCCCC1.,CCN1C(=O)Cc2ccccc2[C@H]1C(=O)NCCC1=CCCCC1,amide642142588,Remove a hydroxyl from the molecule O=C(NC[C@@H](O)c1ccoc1)[C@@H]1COc2ccccc2O1.,O=C(NC[C@@H](O)c1ccoc1)[C@@H]1COc2ccccc2O1,hydroxyl64316353,Remove a nitrile from the molecule CC(C)NC(=O)/C(C#N)=C(/[O-])[C@H]1C[C@@H]1c1ccc(C(C)C)cc1.,CC(C)NC(=O)/C(C#N)=C(/[O-])[C@H]1C[C@@H]1c1ccc(C(C)C)cc1,nitrile644111613,Please remove a amide from the molecule C[C@@H](Sc1nnc2ccc(C(F)(F)F)cn12)C(=O)N(C)C.,C[C@@H](Sc1nnc2ccc(C(F)(F)F)cn12)C(=O)N(C)C,amide64556345,Please remove a amine from the molecule Cc1ccc(C)c(NC(=S)NC[C@@H](c2cccnc2)N2CCOCC2)c1.,Cc1ccc(C)c(NC(=S)NC[C@@H](c2cccnc2)N2CCOCC2)c1,amine64618667,Remove a hydroxyl from the molecule C/C=C(/C)C(=O)O[C@H]1[C@@H](O[C@@]2(C)CC[C@@H](O)[C@@]3(C)CC=C(C(C)C)C[C@@H]23)O[C@H](C)[C@H](O)[C@H]1O.,C/C=C(/C)C(=O)O[C@H]1[C@@H](O[C@@]2(C)CC[C@@H](O)[C@@]3(C)CC=C(C(C)C)C[C@@H]23)O[C@H](C)[C@H](O)[C@H]1O,hydroxyl647157191,Please remove a benzene_ring from the molecule COc1cc(C[NH+](C)CCn2cnnc2)cc(Cl)c1OC.,COc1cc(C[NH+](C)CCn2cnnc2)cc(Cl)c1OC,benzene_ring64838920,Please remove a halo from the molecule C[C@@H](NC(=O)[C@H]1C[C@@H]1c1ccco1)c1noc(-c2ccc(Cl)cc2)n1.,C[C@@H](NC(=O)[C@H]1C[C@@H]1c1ccco1)c1noc(-c2ccc(Cl)cc2)n1,halo64986943,Please remove a amide from the molecule CC(=O)N1CCCc2cc(NC(=O)[C@@H](C)Cc3c(C)n[nH]c3C)ccc21.,CC(=O)N1CCCc2cc(NC(=O)[C@@H](C)Cc3c(C)n[nH]c3C)ccc21,amide65057634,Please remove a amide from the molecule CC1(C)Cc2c(cnn2-c2ccc(F)cc2)[C@@H](NC(=O)CCC(F)(F)F)C1.,CC1(C)Cc2c(cnn2-c2ccc(F)cc2)[C@@H](NC(=O)CCC(F)(F)F)C1,amide651244511,Modify the molecule Cc1occc1COC(=O)c1cccnc1OCC(F)(F)F by removing a halo.,Cc1occc1COC(=O)c1cccnc1OCC(F)(F)F,halo65226592,Please remove a benzene_ring from the molecule C[NH2+][C@@H](CSc1ccc(Cl)cc1)C1CC1.,C[NH2+][C@@H](CSc1ccc(Cl)cc1)C1CC1,benzene_ring65363744,Please remove a amide from the molecule COc1ccc([C@H]2c3nc[nH]c3CCN2C(=O)c2c(C)nc3c(C)cccn23)cc1.,COc1ccc([C@H]2c3nc[nH]c3CCN2C(=O)c2c(C)nc3c(C)cccn23)cc1,amide654178100,Remove a benzene_ring from the molecule C/C(=N\NC(=O)CSc1ccc(Cl)cc1)c1ccc(Br)cc1.,C/C(=N\NC(=O)CSc1ccc(Cl)cc1)c1ccc(Br)cc1,benzene_ring655164909,Please remove a benzene_ring from the molecule Cc1cc(Br)cc([N+](=O)[O-])c1O[C@@H]1CC(=O)C12CCCC2.,Cc1cc(Br)cc([N+](=O)[O-])c1O[C@@H]1CC(=O)C12CCCC2,benzene_ring65682365,Modify the molecule COCC1=C2[C@H](c3cc(OC)ccc3OC)C(C#N)=C(N)O[C@H]2N=N1 by removing a benzene_ring.,COCC1=C2[C@H](c3cc(OC)ccc3OC)C(C#N)=C(N)O[C@H]2N=N1,benzene_ring657240634,Remove a benzene_ring from the molecule CC[C@@H](Oc1cc(Cl)ccc1Cl)C(=O)NNC(=O)[C@H]1[C@@H](C(=O)[O-])[C@H]2CC[C@@H]1C2.,CC[C@@H](Oc1cc(Cl)ccc1Cl)C(=O)NNC(=O)[C@H]1[C@@H](C(=O)[O-])[C@H]2CC[C@@H]1C2,benzene_ring65820516,Please remove a amide from the molecule C=CCNC(=O)c1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1.,C=CCNC(=O)c1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1,amide659222404,Modify the molecule CNC(=O)/C=C/c1ccc(OC(F)F)cc1OC(F)F by removing a benzene_ring.,CNC(=O)/C=C/c1ccc(OC(F)F)cc1OC(F)F,benzene_ring660115485,Please remove a benzene_ring from the molecule CSc1ccc([C@H](O)c2cc(C)c(Cl)cc2C)cc1.,CSc1ccc([C@H](O)c2cc(C)c(Cl)cc2C)cc1,benzene_ring66189866,Modify the molecule C[C@@H](c1ccccc1F)N(C)C(=O)CN(C)C(=O)c1ccccc1 by removing a halo.,C[C@@H](c1ccccc1F)N(C)C(=O)CN(C)C(=O)c1ccccc1,halo662103517,Remove a benzene_ring from the molecule COc1cc(OC)c(C[NH+]2CC[C@H](C)[C@@H](n3ccnc3)C2)c(OC)c1.,COc1cc(OC)c(C[NH+]2CC[C@H](C)[C@@H](n3ccnc3)C2)c(OC)c1,benzene_ring663163614,Modify the molecule COc1ccc([C@@H]2C[C@@H](c3ccc(Cl)c(Cl)c3)Nc3nc(N)nn32)cc1OC by removing a benzene_ring.,COc1ccc([C@@H]2C[C@@H](c3ccc(Cl)c(Cl)c3)Nc3nc(N)nn32)cc1OC,benzene_ring664221454,Modify the molecule C[C@H](c1ccccc1-n1cccn1)n1ccnc1-c1ccco1 by removing a benzene_ring.,C[C@H](c1ccccc1-n1cccn1)n1ccnc1-c1ccco1,benzene_ring665241131,Modify the molecule Cc1cnc2c(c1)N(C(=O)c1ccc(C(F)(F)F)nc1)CCO2 by removing a amide.,Cc1cnc2c(c1)N(C(=O)c1ccc(C(F)(F)F)nc1)CCO2,amide666236975,Remove a benzene_ring from the molecule COc1ccc(-c2ccc(SCc3ccc(F)cc3)nn2)cc1.,COc1ccc(-c2ccc(SCc3ccc(F)cc3)nn2)cc1,benzene_ring6679864,Remove a benzene_ring from the molecule CC(C)Sc1ccccc1C(=O)NCc1ccccn1.,CC(C)Sc1ccccc1C(=O)NCc1ccccn1,benzene_ring668136211,Remove a halo from the molecule O=C(Cc1csc(-c2ccccc2Cl)n1)N[C@H]1CCCNC1=O.,O=C(Cc1csc(-c2ccccc2Cl)n1)N[C@H]1CCCNC1=O,halo669148143,Modify the molecule CC1=NN(c2nc(-c3ccccc3)cs2)C(=O)/C1=N/Nc1cccc([N+](=O)[O-])c1C by removing a amine.,CC1=NN(c2nc(-c3ccccc3)cs2)C(=O)/C1=N/Nc1cccc([N+](=O)[O-])c1C,amine67070115,Please remove a halo from the molecule CCc1ccc(Cl)c(CC)c1NC(=O)[C@H]1CS[C@@]2(C)CCC(=O)N12.,CCc1ccc(Cl)c(CC)c1NC(=O)[C@H]1CS[C@@]2(C)CCC(=O)N12,halo671124757,Modify the molecule COc1ccc(-c2nc(NC3CC[NH2+]CC3)cc(-c3ccncc3)n2)cc1 by removing a benzene_ring.,COc1ccc(-c2nc(NC3CC[NH2+]CC3)cc(-c3ccncc3)n2)cc1,benzene_ring672167678,Modify the molecule C/C(CCc1ccccc1)=N\NC(=O)c1ccc(CN2CCOCC2)cc1 by removing a amide.,C/C(CCc1ccccc1)=N\NC(=O)c1ccc(CN2CCOCC2)cc1,amide673214822,Modify the molecule CCOc1ccc([C@@]2(O)CCCS[C@H]2C)cc1OCC by removing a benzene_ring.,CCOc1ccc([C@@]2(O)CCCS[C@H]2C)cc1OCC,benzene_ring67440207,Please remove a amide from the molecule COCc1ccccc1C(=O)NC[C@H]1C[C@@]12CCc1ccccc12.,COCc1ccccc1C(=O)NC[C@H]1C[C@@]12CCc1ccccc12,amide67550232,Modify the molecule CCc1nn(C)cc1CNC(=O)Nc1ccc(OC2CCOCC2)c(C)c1 by removing a benzene_ring.,CCc1nn(C)cc1CNC(=O)Nc1ccc(OC2CCOCC2)c(C)c1,benzene_ring67698191,Please remove a amine from the molecule NC(=O)[C@@H](NCc1ccc(OC2CCCC2)nc1)c1ccccc1.,NC(=O)[C@@H](NCc1ccc(OC2CCCC2)nc1)c1ccccc1,amine677121095,Please remove a halo from the molecule CCn1nccc1[C@@H](C)[NH2+]Cc1cc(C(F)(F)F)n[nH]1.,CCn1nccc1[C@@H](C)[NH2+]Cc1cc(C(F)(F)F)n[nH]1,halo67873769,Remove a amide from the molecule Cc1ccc(NC(=O)CSc2nnc3c(Cl)cc(C(F)(F)F)cn23)c(Cl)c1.,Cc1ccc(NC(=O)CSc2nnc3c(Cl)cc(C(F)(F)F)cn23)c(Cl)c1,amide679101778,Modify the molecule COCCn1c(C(=O)NCCN2CCN(C(C)=O)CC2)cc2ccccc21 by removing a amide.,COCCn1c(C(=O)NCCN2CCN(C(C)=O)CC2)cc2ccccc21,amide68051446,Remove a halo from the molecule CCC(CC)(C[NH3+])NC(=O)Cc1ccc(F)c(F)c1.,CCC(CC)(C[NH3+])NC(=O)Cc1ccc(F)c(F)c1,halo681218089,Modify the molecule O=C(Cn1nnc(-c2ccccc2Cl)n1)N/N=C/c1cc(Cl)ccc1O by removing a amide.,O=C(Cn1nnc(-c2ccccc2Cl)n1)N/N=C/c1cc(Cl)ccc1O,amide682182858,Remove a amine from the molecule O=C(OCC(=O)N1CCc2ccccc21)c1ccccc1NS(=O)(=O)c1ccc2c(c1)OCCO2.,O=C(OCC(=O)N1CCc2ccccc21)c1ccccc1NS(=O)(=O)c1ccc2c(c1)OCCO2,amine683174031,Please remove a halo from the molecule O=C(NCc1cccn1Cc1cccc(F)c1)Nc1ccccc1C(F)(F)F.,O=C(NCc1cccn1Cc1cccc(F)c1)Nc1ccccc1C(F)(F)F,halo684168019,Remove a halo from the molecule C[C@@H]1CCCC[C@@H]1[NH2+]CCn1ccc2c(Cl)cccc21.,C[C@@H]1CCCC[C@@H]1[NH2+]CCn1ccc2c(Cl)cccc21,halo685212025,Modify the molecule CC(C)(C)OC(=O)N1CCC(N)(C(N)=O)CC1 by removing a amide.,CC(C)(C)OC(=O)N1CCC(N)(C(N)=O)CC1,amide68653801,Please remove a hydroxyl from the molecule COc1ccc(COC[C@@H](O)Cn2cnc3ccccc3c2=O)cc1.,COc1ccc(COC[C@@H](O)Cn2cnc3ccccc3c2=O)cc1,hydroxyl68768499,Modify the molecule CCCNC(=O)[C@@H]1CCCN(C(=O)c2ccc(OC(C)(C)C)cc2)C1 by removing a amide.,CCCNC(=O)[C@@H]1CCCN(C(=O)c2ccc(OC(C)(C)C)cc2)C1,amide688214657,Modify the molecule O=C(Nc1ccc(F)c(F)c1)[C@H]1Nc2cc(F)ccc2S(=O)(=O)N1 by removing a halo.,O=C(Nc1ccc(F)c(F)c1)[C@H]1Nc2cc(F)ccc2S(=O)(=O)N1,halo68990812,Remove a hydroxyl from the molecule OCCc1ccc(OC[C@H]2CO2)cc1.,OCCc1ccc(OC[C@H]2CO2)cc1,hydroxyl690242892,Modify the molecule COC(=O)[C@H](C)NC(=O)[C@@H]1COc2ccc(F)cc2C1 by removing a amide.,COC(=O)[C@H](C)NC(=O)[C@@H]1COc2ccc(F)cc2C1,amide691221250,Modify the molecule OC[C@]1([NH2+]C2CC2)CC[C@@H](Sc2nc3ccccc3[nH]2)C1 by removing a hydroxyl.,OC[C@]1([NH2+]C2CC2)CC[C@@H](Sc2nc3ccccc3[nH]2)C1,hydroxyl692119127,Modify the molecule CCc1ccc([C@H]([NH2+][C@@H]2CCO[C@]3(CCSC3)C2)C(C)C)cc1 by removing a benzene_ring.,CCc1ccc([C@H]([NH2+][C@@H]2CCO[C@]3(CCSC3)C2)C(C)C)cc1,benzene_ring693108791,Remove a benzene_ring from the molecule CCOc1ccc(Nc2nc(-c3cccs3)c(CC(=O)[O-])s2)cc1.,CCOc1ccc(Nc2nc(-c3cccs3)c(CC(=O)[O-])s2)cc1,benzene_ring694133328,Please remove a amide from the molecule CNC(=O)c1cccc(N[C@H](C)C(=O)N2CCOCC2)c1.,CNC(=O)c1cccc(N[C@H](C)C(=O)N2CCOCC2)c1,amide695117326,Please remove a benzene_ring from the molecule Cc1ccccc1[C@H]1CC(c2cccc(NS(C)(=O)=O)c2)=NN1C(=O)C1CCCCC1.,Cc1ccccc1[C@H]1CC(c2cccc(NS(C)(=O)=O)c2)=NN1C(=O)C1CCCCC1,benzene_ring696108225,Modify the molecule C[C@H]1CCCC[C@@H]1NC(=O)COc1cc(O)c2c(c1)OC(C)(C)CC2=O by removing a hydroxyl.,C[C@H]1CCCC[C@@H]1NC(=O)COc1cc(O)c2c(c1)OC(C)(C)CC2=O,hydroxyl69733854,Remove a benzene_ring from the molecule COc1ccc(NC(=O)CN(C)C(=O)c2cccc(N3CCCC3=O)c2)cc1.,COc1ccc(NC(=O)CN(C)C(=O)c2cccc(N3CCCC3=O)c2)cc1,benzene_ring6988817,Please remove a benzene_ring from the molecule C[NH2+][C@H](c1ccc(OC)c(OC)c1)[C@H]1CCO[C@H]1C.,C[NH2+][C@H](c1ccc(OC)c(OC)c1)[C@H]1CCO[C@H]1C,benzene_ring699200665,Remove a benzene_ring from the molecule COc1ccc(C[C@H]([NH3+])c2ccc(OC)cc2)cc1.,COc1ccc(C[C@H]([NH3+])c2ccc(OC)cc2)cc1,benzene_ring700173106,Remove a benzene_ring from the molecule CO[C@H](CNC(=O)NC[C@@H]1CN2CCCC[C@@H]2CO1)c1ccccc1.,CO[C@H](CNC(=O)NC[C@@H]1CN2CCCC[C@@H]2CO1)c1ccccc1,benzene_ring70152707,Modify the molecule CC1=C(C(=O)CSc2nnc(C3=c4ccccc4=[NH+]C3)n2C2CC2)C[C@@H](C)N1C1CC1 by removing a amine.,CC1=C(C(=O)CSc2nnc(C3=c4ccccc4=[NH+]C3)n2C2CC2)C[C@@H](C)N1C1CC1,amine70290296,Remove a halo from the molecule CCN([C@@H](C)CS(=O)(=O)CC)S(=O)(=O)c1c[nH]c2nccc(Cl)c12.,CCN([C@@H](C)CS(=O)(=O)CC)S(=O)(=O)c1c[nH]c2nccc(Cl)c12,halo70350708,Remove a amide from the molecule CCS(=O)(=O)c1ccccc1C(=O)N1CCO[C@H](C)C1.,CCS(=O)(=O)c1ccccc1C(=O)N1CCO[C@H](C)C1,amide704106800,Modify the molecule CC(C)Cn1ncc(C(=O)N[C@@H]2CCCn3nc(C(C)C)nc32)c1C1CC1 by removing a amide.,CC(C)Cn1ncc(C(=O)N[C@@H]2CCCn3nc(C(C)C)nc32)c1C1CC1,amide705111359,Modify the molecule COc1cccc2sc(NC(=O)C[NH+]3CCC[C@@H]([C@@H](C)O)C3)nc12 by removing a amide.,COc1cccc2sc(NC(=O)C[NH+]3CCC[C@@H]([C@@H](C)O)C3)nc12,amide70642603,Remove a amide from the molecule CCc1ccc2oc(=O)cc(C[NH+]3CCC[C@H](N4CCCC4=O)C3)c2c1.,CCc1ccc2oc(=O)cc(C[NH+]3CCC[C@H](N4CCCC4=O)C3)c2c1,amide707197349,Please remove a benzene_ring from the molecule Cc1nn(Cc2ccccc2)c(C)c1C[NH+]1CCC[C@H](n2cccn2)C1.,Cc1nn(Cc2ccccc2)c(C)c1C[NH+]1CCC[C@H](n2cccn2)C1,benzene_ring708244693,Please remove a benzene_ring from the molecule CS(=O)(=O)C1=NN2C(=N)/C(=C\c3ccc(OCc4ccccc4)cc3)C(=O)N=C2S1.,CS(=O)(=O)C1=NN2C(=N)/C(=C\c3ccc(OCc4ccccc4)cc3)C(=O)N=C2S1,benzene_ring709242830,Modify the molecule CC(=O)Nc1nc(C(=O)N[C@H](C)c2ccccn2)cs1 by removing a amide.,CC(=O)Nc1nc(C(=O)N[C@H](C)c2ccccn2)cs1,amide710138302,Please remove a amine from the molecule Cc1cccc2c(CCNC(=O)NN[C@@]3(C)CCS(=O)(=O)C3)c[nH]c12.,Cc1cccc2c(CCNC(=O)NN[C@@]3(C)CCS(=O)(=O)C3)c[nH]c12,amine71118250,Remove a hydroxyl from the molecule CCOC(=O)[C@](C)(O)[C@@H](C)c1cccc2ccccc12.,CCOC(=O)[C@](C)(O)[C@@H](C)c1cccc2ccccc12,hydroxyl712115393,Modify the molecule COC(=O)c1ccc(CN(C)C(=O)c2oc3ccc(F)cc3c2C)cc1 by removing a benzene_ring.,COC(=O)c1ccc(CN(C)C(=O)c2oc3ccc(F)cc3c2C)cc1,benzene_ring713205387,Remove a benzene_ring from the molecule O=C(NCCc1cccc(Cl)c1)c1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1.,O=C(NCCc1cccc(Cl)c1)c1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1,benzene_ring71435191,Remove a amide from the molecule Cc1cc(C)c(O)c(NC(=O)[C@@H]([NH3+])Cc2ccccc2)c1.,Cc1cc(C)c(O)c(NC(=O)[C@@H]([NH3+])Cc2ccccc2)c1,amide71552703,Please remove a amine from the molecule c1ccc([C@H](NCCc2nnc3n2CCCCC3)C2CCCC2)cc1.,c1ccc([C@H](NCCc2nnc3n2CCCCC3)C2CCCC2)cc1,amine716134761,Modify the molecule COC(=O)[C@@H](C)[C@H](C)Sc1ccc(N)c(F)c1 by removing a benzene_ring.,COC(=O)[C@@H](C)[C@H](C)Sc1ccc(N)c(F)c1,benzene_ring717112955,Modify the molecule CCCC(=O)Nc1nn2c(-c3ccc(OC)cc3)nnc2s1 by removing a amide.,CCCC(=O)Nc1nn2c(-c3ccc(OC)cc3)nnc2s1,amide718198945,Please remove a hydroxyl from the molecule C[C@@H]1CCCC[NH+]1C[C@@H]1CCCN(C(=O)[C@H](O)c2ccccc2)C1.,C[C@@H]1CCCC[NH+]1C[C@@H]1CCCN(C(=O)[C@H](O)c2ccccc2)C1,hydroxyl71968991,Please remove a benzene_ring from the molecule CCN(C(=O)CN(CCO)c1ccccc1)C1CC1.,CCN(C(=O)CN(CCO)c1ccccc1)C1CC1,benzene_ring720195060,Please remove a amide from the molecule CCc1ccc([C@@H](C)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1.,CCc1ccc([C@@H](C)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1,amide72149678,Remove a benzene_ring from the molecule CCOC(=O)Cc1csc(NC(=O)c2ccc(C(F)(F)F)cc2)n1.,CCOC(=O)Cc1csc(NC(=O)c2ccc(C(F)(F)F)cc2)n1,benzene_ring722167880,Please remove a amide from the molecule CCN(CC)S(=O)(=O)c1ccc(C(=O)N2CC[C@@H](C)[C@H](O)C2)cc1.,CCN(CC)S(=O)(=O)c1ccc(C(=O)N2CC[C@@H](C)[C@H](O)C2)cc1,amide72392665,Remove a benzene_ring from the molecule Cc1cc([N-]S(=O)(=O)/C=C/c2ccccc2)no1.,Cc1cc([N-]S(=O)(=O)/C=C/c2ccccc2)no1,benzene_ring724147062,Please remove a halo from the molecule CN(Cc1cc(Br)cs1)C(=O)C[NH+](CCO)C1CC1.,CN(Cc1cc(Br)cs1)C(=O)C[NH+](CCO)C1CC1,halo72546045,Modify the molecule CNS(=O)(=O)c1ccc([C@H](C)NCCc2ccccn2)cc1 by removing a amine.,CNS(=O)(=O)c1ccc([C@H](C)NCCc2ccccn2)cc1,amine726131149,Modify the molecule C[C@H]1C[C@H]1c1ccc(/C=C/C(=O)Nc2ccccc2C(=O)NC2CC2)o1 by removing a amide.,C[C@H]1C[C@H]1c1ccc(/C=C/C(=O)Nc2ccccc2C(=O)NC2CC2)o1,amide7271005,Modify the molecule C[C@H]([NH2+][C@H](C)CC(=O)N(C)Cc1cccc(Cl)c1)C1CCC1 by removing a benzene_ring.,C[C@H]([NH2+][C@H](C)CC(=O)N(C)Cc1cccc(Cl)c1)C1CCC1,benzene_ring72847819,Remove a amine from the molecule O=C(Nc1ccc2cn[nH]c2c1)c1csc(Nc2ccccn2)n1.,O=C(Nc1ccc2cn[nH]c2c1)c1csc(Nc2ccccn2)n1,amine729219660,Remove a amine from the molecule C=CCNc1ccc(S(=O)(=O)N2CCC(C)CC2)cc1[N+](=O)[O-].,C=CCNc1ccc(S(=O)(=O)N2CCC(C)CC2)cc1[N+](=O)[O-],amine730213773,Please remove a nitrile from the molecule Cn1nc(C(F)(F)F)c(C#N)c1N1CC[NH+](C(c2ccccc2)c2ccccc2)CC1.,Cn1nc(C(F)(F)F)c(C#N)c1N1CC[NH+](C(c2ccccc2)c2ccccc2)CC1,nitrile73110698,Please remove a benzene_ring from the molecule C[C@@H](Cc1cccs1)NC(=O)C(=O)Nc1cc(F)cc(F)c1.,C[C@@H](Cc1cccs1)NC(=O)C(=O)Nc1cc(F)cc(F)c1,benzene_ring732107117,Remove a amine from the molecule CCNc1ncnc(Nc2cccc(Br)c2)c1[N+](=O)[O-].,CCNc1ncnc(Nc2cccc(Br)c2)c1[N+](=O)[O-],amine733171337,Remove a amide from the molecule COc1ccc(OC)c2sc(N(Cc3cccnc3)C(=O)c3c[nH]c4ccccc34)nc12.,COc1ccc(OC)c2sc(N(Cc3cccnc3)C(=O)c3c[nH]c4ccccc34)nc12,amide73426234,Modify the molecule O=C(Cc1ccc(F)c(F)c1)NC1CC1 by removing a benzene_ring.,O=C(Cc1ccc(F)c(F)c1)NC1CC1,benzene_ring735124374,Remove a amide from the molecule CCC(=O)Nc1ccc(N2CCN(Cc3nc4ccccc4n3C)CC2)c(Cl)c1.,CCC(=O)Nc1ccc(N2CCN(Cc3nc4ccccc4n3C)CC2)c(Cl)c1,amide73659134,Modify the molecule CN(CCC#N)C(=O)CN1CC[NH+](C[C@H](O)C(C)(C)C)CC1 by removing a amide.,CN(CCC#N)C(=O)CN1CC[NH+](C[C@H](O)C(C)(C)C)CC1,amide737189835,Modify the molecule Fc1cc(NCc2nnnn2C2CC2)ccc1Cl by removing a halo.,Fc1cc(NCc2nnnn2C2CC2)ccc1Cl,halo738154488,Modify the molecule CCCn1c([O-])c(C(=O)NNC(=O)c2ccccc2[N+](=O)[O-])c(=O)c2ccccc21 by removing a amide.,CCCn1c([O-])c(C(=O)NNC(=O)c2ccccc2[N+](=O)[O-])c(=O)c2ccccc21,amide739190059,Remove a benzene_ring from the molecule COc1ccc(C[NH2+]CCNc2ccc(F)c(Cl)c2)cc1.,COc1ccc(C[NH2+]CCNc2ccc(F)c(Cl)c2)cc1,benzene_ring740235835,Modify the molecule COc1ccc(Br)cc1[C@H]1C(C#N)=C(N)Oc2cc(C)n(O)c(=O)c21 by removing a benzene_ring.,COc1ccc(Br)cc1[C@H]1C(C#N)=C(N)Oc2cc(C)n(O)c(=O)c21,benzene_ring741231442,Please remove a amide from the molecule COCc1cccc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)c1.,COCc1cccc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)c1,amide742199901,Remove a benzene_ring from the molecule COc1cc(C[NH2+]C[C@@H]2CN3CCCC[C@@H]3CO2)c(SC)cc1OC.,COc1cc(C[NH2+]C[C@@H]2CN3CCCC[C@@H]3CO2)c(SC)cc1OC,benzene_ring743171207,Remove a amide from the molecule O=C(COc1ccc2ccccc2c1)Nc1cccc(C(=O)N2CCCCC2)c1.,O=C(COc1ccc2ccccc2c1)Nc1cccc(C(=O)N2CCCCC2)c1,amide744170640,Modify the molecule COC(=O)[C@@H](C)N1C(=O)S/C(=C/c2ccc(-c3ccccc3C#N)o2)C1=O by removing a nitrile.,COC(=O)[C@@H](C)N1C(=O)S/C(=C/c2ccc(-c3ccccc3C#N)o2)C1=O,nitrile745241050,Please remove a amide from the molecule COC(=O)c1cccc2c1CCCN2C(=O)CCCn1cnc2c(C)cccc2c1=O.,COC(=O)c1cccc2c1CCCN2C(=O)CCCn1cnc2c(C)cccc2c1=O,amide74639027,Remove a amide from the molecule O=C(Nc1ccn(Cc2ccccc2)n1)c1cc(Cl)ccc1Cl.,O=C(Nc1ccn(Cc2ccccc2)n1)c1cc(Cl)ccc1Cl,amide747124415,Please remove a benzene_ring from the molecule COc1ccc(C(=O)c2coc3ccc(O)c(C[NH+](C)C)c23)cc1.,COc1ccc(C(=O)c2coc3ccc(O)c(C[NH+](C)C)c23)cc1,benzene_ring74810906,Modify the molecule O=C(Nc1ccc(F)c(F)c1)[C@H]1CCCN(c2ccc(-n3ccnc3)nn2)C1 by removing a benzene_ring.,O=C(Nc1ccc(F)c(F)c1)[C@H]1CCCN(c2ccc(-n3ccnc3)nn2)C1,benzene_ring74999046,Please remove a hydroxyl from the molecule O=c1c2ccccc2oc2cc3c(c(O)c12)CCCC3.,O=c1c2ccccc2oc2cc3c(c(O)c12)CCCC3,hydroxyl750233185,Modify the molecule NC1=C(Br)[C@H](C(F)(F)F)N=N1 by removing a halo.,NC1=C(Br)[C@H](C(F)(F)F)N=N1,halo751141008,Please remove a benzene_ring from the molecule COc1ccccc1C[C@H](C)N(C)C(=O)NC[C@H]1CN2CCCC[C@@H]2CO1.,COc1ccccc1C[C@H](C)N(C)C(=O)NC[C@H]1CN2CCCC[C@@H]2CO1,benzene_ring752126383,Modify the molecule Nc1ccc(F)c(NC(=O)CC[NH+]2CCCCCCC2)c1 by removing a benzene_ring.,Nc1ccc(F)c(NC(=O)CC[NH+]2CCCCCCC2)c1,benzene_ring753229003,Please remove a nitrile from the molecule N#C[C@H]1CN(C(=O)c2c(O)cccc2O)CCN1Cc1ccccc1.,N#C[C@H]1CN(C(=O)c2c(O)cccc2O)CCN1Cc1ccccc1,nitrile75439602,Modify the molecule CCOc1ccc(C(=O)N(Cc2ccco2)c2nc3c(F)cccc3s2)cc1 by removing a benzene_ring.,CCOc1ccc(C(=O)N(Cc2ccco2)c2nc3c(F)cccc3s2)cc1,benzene_ring755242904,Remove a halo from the molecule Cc1sc(Br)cc1S(=O)(=O)N1CCO[C@@H](C#N)C1.,Cc1sc(Br)cc1S(=O)(=O)N1CCO[C@@H](C#N)C1,halo756155383,Please remove a nitrile from the molecule N#Cc1cccc(CNC(=O)N(Cc2cccnc2)C[C@H]2CCCO2)c1.,N#Cc1cccc(CNC(=O)N(Cc2cccnc2)C[C@H]2CCCO2)c1,nitrile757199243,Remove a halo from the molecule N#Cc1nc(-c2ccccc2)c(-c2ccccc2)nc1Cl.,N#Cc1nc(-c2ccccc2)c(-c2ccccc2)nc1Cl,halo758143897,Modify the molecule Cc1occc1C(=O)[C@@H](C#N)c1nc(-c2ccc(C#N)cc2)cs1 by removing a benzene_ring.,Cc1occc1C(=O)[C@@H](C#N)c1nc(-c2ccc(C#N)cc2)cs1,benzene_ring759143127,Modify the molecule O=C(CN1C(=O)/C(=C/c2cccs2)SC1=S)Nc1cc(C(=O)[O-])ccc1C(=O)[O-] by removing a benzene_ring.,O=C(CN1C(=O)/C(=C/c2cccs2)SC1=S)Nc1cc(C(=O)[O-])ccc1C(=O)[O-],benzene_ring760110308,Modify the molecule CC(C)CC1=C[C@H]([C@H]2NN[C@H]3SC(c4ccc5c(c4)OCCO5)=NN23)N=N1 by removing a amine.,CC(C)CC1=C[C@H]([C@H]2NN[C@H]3SC(c4ccc5c(c4)OCCO5)=NN23)N=N1,amine76174129,Remove a benzene_ring from the molecule CCC[C@H]([NH2+]Cc1ccc(C)cc1)c1ccccc1.,CCC[C@H]([NH2+]Cc1ccc(C)cc1)c1ccccc1,benzene_ring76229942,Remove a amine from the molecule Cc1nn(-c2nc3c(Cl)c(Cl)ccc3s2)c(C)c1C(=O)NN.,Cc1nn(-c2nc3c(Cl)c(Cl)ccc3s2)c(C)c1C(=O)NN,amine76319020,Modify the molecule COc1cc(F)c([N+](=O)[O-])c(NCCCc2nnc3n2CCCCC3)c1 by removing a halo.,COc1cc(F)c([N+](=O)[O-])c(NCCCc2nnc3n2CCCCC3)c1,halo764217105,Modify the molecule CCC[C@@H]1C[C@@H]1NC(=O)c1oc2ccccc2c1C[NH+](C)C by removing a amide.,CCC[C@@H]1C[C@@H]1NC(=O)c1oc2ccccc2c1C[NH+](C)C,amide76556003,Modify the molecule Cc1nn(C)c(C[C@H]([NH3+])[C@@]2(C)CCCO2)c1Cl by removing a halo.,Cc1nn(C)c(C[C@H]([NH3+])[C@@]2(C)CCCO2)c1Cl,halo76654221,Remove a benzene_ring from the molecule COc1cccc(F)c1[C@H](C)NC(=O)NCC[NH+]1CCC(OC)CC1.,COc1cccc(F)c1[C@H](C)NC(=O)NCC[NH+]1CCC(OC)CC1,benzene_ring767152905,Remove a benzene_ring from the molecule COc1cccc(OC)c1OC(=O)Cn1c(=O)sc2ccccc21.,COc1cccc(OC)c1OC(=O)Cn1c(=O)sc2ccccc21,benzene_ring76853369,Please remove a amide from the molecule CN(CCc1ccccc1)C(=O)c1occc1Br.,CN(CCc1ccccc1)C(=O)c1occc1Br,amide769188798,Please remove a halo from the molecule CCOc1ccccc1CN(C[C@H]1CCCO1)C(=O)Nc1cccc(Cl)c1.,CCOc1ccccc1CN(C[C@H]1CCCO1)C(=O)Nc1cccc(Cl)c1,halo770152906,Modify the molecule CCc1nc2c(s1)[C@@H](N(C)C(C)=O)CCC2 by removing a amide.,CCc1nc2c(s1)[C@@H](N(C)C(C)=O)CCC2,amide771204974,Remove a halo from the molecule C[C@@H]([NH2+]Cc1csc(C2CC2)n1)c1ccc(Cl)s1.,C[C@@H]([NH2+]Cc1csc(C2CC2)n1)c1ccc(Cl)s1,halo772228105,Modify the molecule CC(C)CNC(=O)CNC(=O)N1Cc2ccccc2N(C)C[C@@H]1C by removing a amide.,CC(C)CNC(=O)CNC(=O)N1Cc2ccccc2N(C)C[C@@H]1C,amide77378635,Remove a amide from the molecule CCSc1nnc(NC(=O)/C=C/Sc2ccccc2)s1.,CCSc1nnc(NC(=O)/C=C/Sc2ccccc2)s1,amide774126133,Please remove a nitrile from the molecule CCSCCOC(=O)/C=C/c1cccc(C#N)c1.,CCSCCOC(=O)/C=C/c1cccc(C#N)c1,nitrile77544212,Please remove a amide from the molecule C[C@H]1CCC[NH+]([C@@H](C)CNC(=O)C(=O)Nc2ccc3[nH]ncc3c2)C1.,C[C@H]1CCC[NH+]([C@@H](C)CNC(=O)C(=O)Nc2ccc3[nH]ncc3c2)C1,amide776226965,Remove a amide from the molecule CC1=NN[C@H](SCC(=O)Nc2nc(C)cs2)N1C.,CC1=NN[C@H](SCC(=O)Nc2nc(C)cs2)N1C,amide777228754,Remove a benzene_ring from the molecule N#Cc1ccc(OCc2ccc(C(=O)N=c3[nH]c4ccccc4[nH]3)o2)cc1.,N#Cc1ccc(OCc2ccc(C(=O)N=c3[nH]c4ccccc4[nH]3)o2)cc1,benzene_ring77880910,Please remove a halo from the molecule CC(C)/C=C/C(=O)N1CCc2nnc(CNC(=O)c3cccc(F)c3)n2CC1.,CC(C)/C=C/C(=O)N1CCc2nnc(CNC(=O)c3cccc(F)c3)n2CC1,halo779149924,Modify the molecule Cc1cc(C(=O)NCCC/C(N)=N/O)sc1Br by removing a amine.,Cc1cc(C(=O)NCCC/C(N)=N/O)sc1Br,amine780133900,Please remove a hydroxyl from the molecule Cc1cc(C(=O)N(C)[C@@H](C)C(C)(C)C)sc1C#CCCO.,Cc1cc(C(=O)N(C)[C@@H](C)C(C)(C)C)sc1C#CCCO,hydroxyl78171703,Please remove a benzene_ring from the molecule CC(C)[NH2+][C@@H]1CC(=O)N(Cc2cccc(F)c2)C1.,CC(C)[NH2+][C@@H]1CC(=O)N(Cc2cccc(F)c2)C1,benzene_ring78220191,Please remove a nitrile from the molecule CC(C)c1nc([C@H]2CCCN2c2ncc(C#N)cc2Cl)no1.,CC(C)c1nc([C@H]2CCCN2c2ncc(C#N)cc2Cl)no1,nitrile78337419,Remove a amide from the molecule CC(C)(C)NC(=O)[C@H]1COc2ccccc2O1.,CC(C)(C)NC(=O)[C@H]1COc2ccccc2O1,amide784200988,Remove a benzene_ring from the molecule Cc1cc([C@H]2[C@@H](C[NH2+]C3CC3)CCCN2C)ccc1Br.,Cc1cc([C@H]2[C@@H](C[NH2+]C3CC3)CCCN2C)ccc1Br,benzene_ring785158917,Please remove a benzene_ring from the molecule COc1c(C)cc(S(=O)(=O)NCC[C@H](O)C2CC2)cc1C.,COc1c(C)cc(S(=O)(=O)NCC[C@H](O)C2CC2)cc1C,benzene_ring786152685,Modify the molecule O=C1OCCN1c1cccc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)c1 by removing a halo.,O=C1OCCN1c1cccc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)c1,halo78798821,Remove a amine from the molecule CC/[NH+]=C(/NCc1nnc2n1CCCCC2)N[C@@H]1C[C@@H]1C.,CC/[NH+]=C(/NCc1nnc2n1CCCCC2)N[C@@H]1C[C@@H]1C,amine788172186,Remove a halo from the molecule Cc1cc(F)c([C@@H](C)CC[NH3+])cc1F.,Cc1cc(F)c([C@@H](C)CC[NH3+])cc1F,halo78930686,Remove a halo from the molecule Cc1ccc(NC(=O)[C@@H]2C[C@H]3CC[C@@H]2O3)cc1Br.,Cc1ccc(NC(=O)[C@@H]2C[C@H]3CC[C@@H]2O3)cc1Br,halo79020514,Remove a amide from the molecule COCC(=O)N1CCCN(Cc2cnc(-c3ccccn3)nc2)CC1.,COCC(=O)N1CCCN(Cc2cnc(-c3ccccn3)nc2)CC1,amide791151517,Please remove a amide from the molecule CN1C[C@@H](NC(=O)NCc2ccnc(OC3CCC3)c2)CCC1=O.,CN1C[C@@H](NC(=O)NCc2ccnc(OC3CCC3)c2)CCC1=O,amide79234842,Please remove a amide from the molecule CC(C)[C@@H](NC(=O)C(=O)Nc1cccc(-c2ncon2)c1)c1ccccn1.,CC(C)[C@@H](NC(=O)C(=O)Nc1cccc(-c2ncon2)c1)c1ccccn1,amide793108153,Modify the molecule O=C(NNC(=S)[S-])c1cnccn1 by removing a amine.,O=C(NNC(=S)[S-])c1cnccn1,amine79425001,Modify the molecule O=c1c(-c2nccs2)nc2ccc(NCc3c(F)cccc3F)nc2n1Cc1ccncc1 by removing a halo.,O=c1c(-c2nccs2)nc2ccc(NCc3c(F)cccc3F)nc2n1Cc1ccncc1,halo795220339,Remove a benzene_ring from the molecule CCc1ccc(C[NH2+]Cc2ccccc2)cc1.,CCc1ccc(C[NH2+]Cc2ccccc2)cc1,benzene_ring796206890,Modify the molecule C[C@@H](SCc1ccccc1)C(=O)NC[C@@H](C)N1CC[NH+](C)CC1 by removing a benzene_ring.,C[C@@H](SCc1ccccc1)C(=O)NC[C@@H](C)N1CC[NH+](C)CC1,benzene_ring79766611,Please remove a halo from the molecule CSCc1cc(F)ccc1CNC(=O)c1c(F)cccc1Cl.,CSCc1cc(F)ccc1CNC(=O)c1c(F)cccc1Cl,halo798245427,Modify the molecule C[C@H]1C[C@@H]1NC(=O)c1c[nH]nc1-c1cccc(OC(F)F)c1 by removing a amide.,C[C@H]1C[C@@H]1NC(=O)c1c[nH]nc1-c1cccc(OC(F)F)c1,amide799244919,Please remove a amine from the molecule COc1ccc(OC)c(NS(=O)(=O)c2ccc(CC(C)C)cc2)c1.,COc1ccc(OC)c(NS(=O)(=O)c2ccc(CC(C)C)cc2)c1,amine800123382,Modify the molecule Cc1ccc(NC(=O)[C@H](C)Cc2cccc(C(F)(F)F)c2)cc1C(N)=O by removing a benzene_ring.,Cc1ccc(NC(=O)[C@H](C)Cc2cccc(C(F)(F)F)c2)cc1C(N)=O,benzene_ring801140818,Please remove a amide from the molecule COc1cc(NC(=O)c2cc(C)cc(C)c2)c(OC)cc1NC(=O)c1ccccc1.,COc1cc(NC(=O)c2cc(C)cc(C)c2)c(OC)cc1NC(=O)c1ccccc1,amide802192378,Please remove a halo from the molecule Cc1cccc(-n2c(C)cc(C(=O)C(=O)Nc3ccccc3F)c2C)c1C.,Cc1cccc(-n2c(C)cc(C(=O)C(=O)Nc3ccccc3F)c2C)c1C,halo80366648,Modify the molecule CC(=O)Nc1nc(SCC(=O)N2C[C@H](C)O[C@H](C)C2)[nH]c(=O)c1NC(=O)c1ccccc1 by removing a amide.,CC(=O)Nc1nc(SCC(=O)N2C[C@H](C)O[C@H](C)C2)[nH]c(=O)c1NC(=O)c1ccccc1,amide80461847,Modify the molecule Cc1cncc(C(=O)N2CCCc3cc(C)ccc32)c1 by removing a amide.,Cc1cncc(C(=O)N2CCCc3cc(C)ccc32)c1,amide805160161,Modify the molecule O=C(C1CCN([C@H]2CCS(=O)(=O)C2)CC1)N1CCN(Cc2ccc3c(c2)CCO3)CC1 by removing a amide.,O=C(C1CCN([C@H]2CCS(=O)(=O)C2)CC1)N1CCN(Cc2ccc3c(c2)CCO3)CC1,amide806115968,Remove a benzene_ring from the molecule Cn1c(SC(c2ccccc2)c2ccccc2)nnc1[C@H]1COc2ccccc2O1.,Cn1c(SC(c2ccccc2)c2ccccc2)nnc1[C@H]1COc2ccccc2O1,benzene_ring807202906,Please remove a benzene_ring from the molecule CC(=O)Nc1cccc([C@H](C)NC(=O)CCc2ncc(-c3ccc(C)c(C)c3)o2)c1.,CC(=O)Nc1cccc([C@H](C)NC(=O)CCc2ncc(-c3ccc(C)c(C)c3)o2)c1,benzene_ring808185711,Please remove a halo from the molecule CC(C)(C)OC(=O)c1nc([O-])n(-c2ccc(Br)cc2)n1.,CC(C)(C)OC(=O)c1nc([O-])n(-c2ccc(Br)cc2)n1,halo809125072,Remove a amide from the molecule CC(C)(C#N)CCCNc1ccccc1C(=O)N1CCC[C@@H]1CO.,CC(C)(C#N)CCCNc1ccccc1C(=O)N1CCC[C@@H]1CO,amide810104792,Remove a benzene_ring from the molecule N#Cc1csc(C(=O)NCc2cccc(NC(=O)C3CCCC3)c2)c1.,N#Cc1csc(C(=O)NCc2cccc(NC(=O)C3CCCC3)c2)c1,benzene_ring81197535,Please remove a amide from the molecule Cn1nc(C(F)(F)F)c2cc(C(=O)N3C[C@@H]4CC[C@H](C3)[NH+](C)C4)sc21.,Cn1nc(C(F)(F)F)c2cc(C(=O)N3C[C@@H]4CC[C@H](C3)[NH+](C)C4)sc21,amide812170009,Remove a benzene_ring from the molecule COc1ccc(F)c(N2C(=O)CNC(=O)[C@@H]2C(C)C)c1.,COc1ccc(F)c(N2C(=O)CNC(=O)[C@@H]2C(C)C)c1,benzene_ring813108540,Modify the molecule CNS(=O)(=O)c1ccc(N(C)Cc2ccc(Br)cc2)c([N+](=O)[O-])c1 by removing a halo.,CNS(=O)(=O)c1ccc(N(C)Cc2ccc(Br)cc2)c([N+](=O)[O-])c1,halo814175244,Modify the molecule CC(C)OCCCNC(=O)C1CCN(C(=O)[C@@H]2CCO[C@H]2C)CC1 by removing a amide.,CC(C)OCCCNC(=O)C1CCN(C(=O)[C@@H]2CCO[C@H]2C)CC1,amide815188811,Modify the molecule CC(C)N(C)C(=O)CCc1nnc(-c2ccsc2)o1 by removing a amide.,CC(C)N(C)C(=O)CCc1nnc(-c2ccsc2)o1,amide816237720,Modify the molecule O=C(NCc1ccncc1)N(Cc1ccc(O)cc1)CC1CC1 by removing a hydroxyl.,O=C(NCc1ccncc1)N(Cc1ccc(O)cc1)CC1CC1,hydroxyl81714669,Remove a amine from the molecule COc1ccccc1CNc1nc2ccc(Cl)cc2nc1-n1nc(C)cc1C.,COc1ccccc1CNc1nc2ccc(Cl)cc2nc1-n1nc(C)cc1C,amine818238505,Remove a benzene_ring from the molecule COc1ccc(C2=N[C@H](c3ccc(F)c(Br)c3)N[C@H](c3ccccc3O)C2)cc1.,COc1ccc(C2=N[C@H](c3ccc(F)c(Br)c3)N[C@H](c3ccccc3O)C2)cc1,benzene_ring81995571,Modify the molecule Cc1cc(C)c(C(=O)NCCNc2ccccc2)c(=O)[nH]1 by removing a amine.,Cc1cc(C)c(C(=O)NCCNc2ccccc2)c(=O)[nH]1,amine820179431,Modify the molecule Cc1cc(CC(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)no1 by removing a benzene_ring.,Cc1cc(CC(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)no1,benzene_ring821181747,Remove a benzene_ring from the molecule CCOc1c(F)cccc1C(=O)Nc1ccc(-n2ccnc2)cc1.,CCOc1c(F)cccc1C(=O)Nc1ccc(-n2ccnc2)cc1,benzene_ring822243505,Modify the molecule Nc1nc(C(=O)Nc2ccccc2)cs1 by removing a amine.,Nc1nc(C(=O)Nc2ccccc2)cs1,amine823226142,Modify the molecule CC(C)(C)[C@](O)(Cn1cncn1)[C@@H]1O[C@@H]1c1ccc(Cl)cc1 by removing a hydroxyl.,CC(C)(C)[C@](O)(Cn1cncn1)[C@@H]1O[C@@H]1c1ccc(Cl)cc1,hydroxyl82483388,Modify the molecule O=C(Nc1ccc2[nH]ccc2c1)C(=O)N[C@@H](c1nccs1)C1CC1 by removing a amide.,O=C(Nc1ccc2[nH]ccc2c1)C(=O)N[C@@H](c1nccs1)C1CC1,amide825245383,Remove a benzene_ring from the molecule C[C@H](C[NH+](C)CC(C)(C)S(C)(=O)=O)c1cccc(Br)c1.,C[C@H](C[NH+](C)CC(C)(C)S(C)(=O)=O)c1cccc(Br)c1,benzene_ring82632010,Modify the molecule Cc1ccc(N2C[C@H](C(=O)N3CC[C@H](c4ccccc4)C3)CC2=O)cc1 by removing a benzene_ring.,Cc1ccc(N2C[C@H](C(=O)N3CC[C@H](c4ccccc4)C3)CC2=O)cc1,benzene_ring82755338,Remove a amide from the molecule CNC(=O)C[NH+](C)Cc1cc(Cl)cc(Cl)c1.,CNC(=O)C[NH+](C)Cc1cc(Cl)cc(Cl)c1,amide828209866,Please remove a amide from the molecule Cc1ccc(C(=O)N(C)Cc2nnn[n-]2)cc1.,Cc1ccc(C(=O)N(C)Cc2nnn[n-]2)cc1,amide82975739,Modify the molecule COc1ccc(CNC(=O)N[C@@H]2C=C[C@H](CO)C2)c(OC2CCCC2)c1 by removing a benzene_ring.,COc1ccc(CNC(=O)N[C@@H]2C=C[C@H](CO)C2)c(OC2CCCC2)c1,benzene_ring830199713,Remove a halo from the molecule CN(Cc1ccccc1C(F)(F)F)C(=O)NCCc1cccc(F)c1.,CN(Cc1ccccc1C(F)(F)F)C(=O)NCCc1cccc(F)c1,halo83127706,Please remove a halo from the molecule C[C@H]1C[C@@H](N2CCN(c3cccc(Cl)c3)CC2)C(=O)O1.,C[C@H]1C[C@@H](N2CCN(c3cccc(Cl)c3)CC2)C(=O)O1,halo83275672,Remove a benzene_ring from the molecule C[C@@H]1CCCC[C@@H]1[NH+](C)Cc1cc(F)cc(C#CC[NH3+])c1.,C[C@@H]1CCCC[C@@H]1[NH+](C)Cc1cc(F)cc(C#CC[NH3+])c1,benzene_ring833172801,Remove a amide from the molecule Cc1ccc(N2CCn3c2nnc(C(=O)NCc2cccs2)c3=O)cc1.,Cc1ccc(N2CCn3c2nnc(C(=O)NCc2cccs2)c3=O)cc1,amide83483727,Please remove a amide from the molecule COc1ccc(Cl)cc1NC(=O)[C@@H]1CN(C(C)=O)c2ccccc2O1.,COc1ccc(Cl)cc1NC(=O)[C@@H]1CN(C(C)=O)c2ccccc2O1,amide835203696,Modify the molecule CCn1nnnc1-c1ccc(OC)c(S(=O)(=O)Nc2ccc(C)c(C)c2)c1 by removing a amine.,CCn1nnnc1-c1ccc(OC)c(S(=O)(=O)Nc2ccc(C)c(C)c2)c1,amine83680906,Please remove a amide from the molecule Cc1noc(C)c1S(=O)(=O)NCCNC(=O)c1cccn1C.,Cc1noc(C)c1S(=O)(=O)NCCNC(=O)c1cccn1C,amide837810,Modify the molecule O=C(Nc1ccccc1)NC1CCN(C(=O)[C@H]2CCCC[C@H]2C(F)(F)F)CC1 by removing a amide.,O=C(Nc1ccccc1)NC1CCN(C(=O)[C@H]2CCCC[C@H]2C(F)(F)F)CC1,amide838137152,Please remove a hydroxyl from the molecule C[C@H]1CCN(C(=O)COc2ccccc2Br)C[C@H]1O.,C[C@H]1CCN(C(=O)COc2ccccc2Br)C[C@H]1O,hydroxyl839143959,Please remove a benzene_ring from the molecule CCOc1cccnc1C(=O)O[C@@H](C)c1cccc(OC)c1.,CCOc1cccnc1C(=O)O[C@@H](C)c1cccc(OC)c1,benzene_ring840170455,Modify the molecule C[C@@H](N[C@H](c1cccnc1)c1ccc(F)c(F)c1)c1cnn(C)c1 by removing a benzene_ring.,C[C@@H](N[C@H](c1cccnc1)c1ccc(F)c(F)c1)c1cnn(C)c1,benzene_ring841239448,Remove a benzene_ring from the molecule COC(=O)CNC(=O)CCN1CCO[C@@H](c2ccccc2Br)C1.,COC(=O)CNC(=O)CCN1CCO[C@@H](c2ccccc2Br)C1,benzene_ring84274853,Remove a benzene_ring from the molecule Cc1cc(N(C)C)cc(C)c1NC(=O)CCn1cnc2ccccc21.,Cc1cc(N(C)C)cc(C)c1NC(=O)CCn1cnc2ccccc21,benzene_ring8434182,Remove a amide from the molecule COCCNC(=O)[C@@H](C)CS(=O)(=O)c1ccc(Br)cc1.,COCCNC(=O)[C@@H](C)CS(=O)(=O)c1ccc(Br)cc1,amide84436912,Remove a benzene_ring from the molecule COc1ccc(NC(=O)Cn2cnc(C3CCC3)cc2=O)c([N+](=O)[O-])c1.,COc1ccc(NC(=O)Cn2cnc(C3CCC3)cc2=O)c([N+](=O)[O-])c1,benzene_ring845115180,Please remove a amide from the molecule C[C@@H](c1nc2ccccc2s1)N(C)C(=O)c1cccc(Nc2ncccn2)c1.,C[C@@H](c1nc2ccccc2s1)N(C)C(=O)c1cccc(Nc2ncccn2)c1,amide84636740,Please remove a benzene_ring from the molecule N#C[C@@H]1CCC[C@H]1Sc1ccccc1Br.,N#C[C@@H]1CCC[C@H]1Sc1ccccc1Br,benzene_ring847183095,Remove a amide from the molecule C[C@@H](c1cccnc1)N(C)C(=O)Nc1ccn(CCCC(=O)N(C)C)n1.,C[C@@H](c1cccnc1)N(C)C(=O)Nc1ccn(CCCC(=O)N(C)C)n1,amide8484357,Please remove a amide from the molecule NC(=O)c1cc([N+](=O)[O-])ccc1O[C@H]1CCC[C@@H]([NH3+])C1.,NC(=O)c1cc([N+](=O)[O-])ccc1O[C@H]1CCC[C@@H]([NH3+])C1,amide849249133,Modify the molecule COc1ccc(/C=C2\CCCc3c2nc2ccccc2c3C(=O)OCC(N)=O)cc1 by removing a amide.,COc1ccc(/C=C2\CCCc3c2nc2ccccc2c3C(=O)OCC(N)=O)cc1,amide85060971,Modify the molecule CCO[C@H]1C[C@@H](NC(=O)C(=O)Nc2cc(C(C)C)on2)C12CCCC2 by removing a amide.,CCO[C@H]1C[C@@H](NC(=O)C(=O)Nc2cc(C(C)C)on2)C12CCCC2,amide851233071,Modify the molecule C[C@@H](NC(=O)c1ccc(Cl)cc1)C(=O)Nc1ccc(N2CC[NH+](C)CC2)nc1 by removing a halo.,C[C@@H](NC(=O)c1ccc(Cl)cc1)C(=O)Nc1ccc(N2CC[NH+](C)CC2)nc1,halo852200537,Modify the molecule O=C(Nc1cc(F)ccc1F)[C@H]1CCS(=O)(=O)C1 by removing a halo.,O=C(Nc1cc(F)ccc1F)[C@H]1CCS(=O)(=O)C1,halo853243683,Remove a amide from the molecule CO[C@@H](C)C(=O)Nc1cccc(NS(=O)(=O)c2cc(C)ccc2F)c1.,CO[C@@H](C)C(=O)Nc1cccc(NS(=O)(=O)c2cc(C)ccc2F)c1,amide854145495,Modify the molecule C[NH2+]C[C@H](C)C(=O)NC[C@H]1CCC(=O)N1 by removing a amide.,C[NH2+]C[C@H](C)C(=O)NC[C@H]1CCC(=O)N1,amide855209480,Please remove a amine from the molecule CN/C(=[NH+]\C)SCC(=O)N(C)Cc1ccc(Cl)s1.,CN/C(=[NH+]\C)SCC(=O)N(C)Cc1ccc(Cl)s1,amine856229002,Remove a amide from the molecule C[C@H]1C[C@@H]1c1ccc(CN(C)C(=O)c2ccc(NC(N)=O)cc2)o1.,C[C@H]1C[C@@H]1c1ccc(CN(C)C(=O)c2ccc(NC(N)=O)cc2)o1,amide85738809,Modify the molecule O=C([O-])[C@H]1CCCCN1C(=O)c1nc(C2CC2)n[nH]1 by removing a amide.,O=C([O-])[C@H]1CCCCN1C(=O)c1nc(C2CC2)n[nH]1,amide858141594,Modify the molecule CCN(C(=O)c1cccc(C(F)(F)F)c1F)C1C[NH2+]C1 by removing a amide.,CCN(C(=O)c1cccc(C(F)(F)F)c1F)C1C[NH2+]C1,amide85955697,Please remove a amide from the molecule COc1ccc(-c2ccc(=O)n([C@@H](C)C(=O)Nc3ccc(OC)c(OC)c3)n2)cc1.,COc1ccc(-c2ccc(=O)n([C@@H](C)C(=O)Nc3ccc(OC)c(OC)c3)n2)cc1,amide860194457,Remove a hydroxyl from the molecule CC[C@@H](CO)N1CC[NH+](C2CCC(C(C)C)CC2)CC1.,CC[C@@H](CO)N1CC[NH+](C2CCC(C(C)C)CC2)CC1,hydroxyl861232000,Modify the molecule Cc1cc(-c2c(-c3ccccc3)ncn2CCCO)cc(C)c1O by removing a benzene_ring.,Cc1cc(-c2c(-c3ccccc3)ncn2CCCO)cc(C)c1O,benzene_ring862120031,Remove a amide from the molecule CC(C)c1n[nH]c([C@H]2CN(C(=O)c3ccc(=O)n(C)n3)CCO2)n1.,CC(C)c1n[nH]c([C@H]2CN(C(=O)c3ccc(=O)n(C)n3)CCO2)n1,amide86317279,Modify the molecule Cc1cc(N2CC[C@@H](N[C@H](C)c3cccnc3Cl)C2=O)n(C)n1 by removing a amine.,Cc1cc(N2CC[C@@H](N[C@H](C)c3cccnc3Cl)C2=O)n(C)n1,amine864149249,Please remove a halo from the molecule COc1ccc(CC(=O)NCc2ccccc2F)cc1OC.,COc1ccc(CC(=O)NCc2ccccc2F)cc1OC,halo865148976,Modify the molecule CCOC(=O)c1c(NC(=O)CSc2n[nH]c(N)n2)sc2c1CC[C@H](C)C2 by removing a amide.,CCOC(=O)c1c(NC(=O)CSc2n[nH]c(N)n2)sc2c1CC[C@H](C)C2,amide866208090,Please remove a benzene_ring from the molecule O=c1c(Cc2ccc(Cl)cc2)c([O-])ccn1Cc1ccccc1.,O=c1c(Cc2ccc(Cl)cc2)c([O-])ccn1Cc1ccccc1,benzene_ring86763264,Modify the molecule Cc1ccccc1[C@H]1CN(C(=O)C(=O)Nc2ccc(F)cc2F)CCO1 by removing a amide.,Cc1ccccc1[C@H]1CN(C(=O)C(=O)Nc2ccc(F)cc2F)CCO1,amide868133571,Modify the molecule C[C@@H](Cc1nc2ccccc2s1)N[C@H](C)c1cn(-c2ccccc2)nn1 by removing a benzene_ring.,C[C@@H](Cc1nc2ccccc2s1)N[C@H](C)c1cn(-c2ccccc2)nn1,benzene_ring869234871,Please remove a benzene_ring from the molecule CC[S@](=O)[C@@H]1CCCC[C@@H]1NC(=O)NC(C)(C)c1cccc(C)c1.,CC[S@](=O)[C@@H]1CCCC[C@@H]1NC(=O)NC(C)(C)c1cccc(C)c1,benzene_ring870109403,Modify the molecule Fc1ccc(OCC2=NN3[C@@H]([C@H]4C=c5ccccc5=[NH+]4)NN[C@H]3S2)cc1 by removing a amine.,Fc1ccc(OCC2=NN3[C@@H]([C@H]4C=c5ccccc5=[NH+]4)NN[C@H]3S2)cc1,amine871105219,Modify the molecule Cc1ccc(S(=O)(=O)N(C)c2ccc(O[C@H](C)C(=O)Nc3c(C)cc(C)cc3C)cc2)cc1 by removing a benzene_ring.,Cc1ccc(S(=O)(=O)N(C)c2ccc(O[C@H](C)C(=O)Nc3c(C)cc(C)cc3C)cc2)cc1,benzene_ring87223956,Modify the molecule Cc1ccc(NC(=S)NC(=O)c2ccccc2[N+](=O)[O-])c(C)c1 by removing a benzene_ring.,Cc1ccc(NC(=S)NC(=O)c2ccccc2[N+](=O)[O-])c(C)c1,benzene_ring87371959,Modify the molecule Cn1c(N2CC[C@H](O)C2)nc2cc(C(=O)NCCCOc3ccccc3)ccc21 by removing a amide.,Cn1c(N2CC[C@H](O)C2)nc2cc(C(=O)NCCCOc3ccccc3)ccc21,amide874107238,Modify the molecule O=C(/C=C/c1ccc(F)cc1)NC(=S)NNS(=O)(=O)c1ccccc1 by removing a amide.,O=C(/C=C/c1ccc(F)cc1)NC(=S)NNS(=O)(=O)c1ccccc1,amide875117390,Modify the molecule CNC(=O)CN1CCC([NH2+][C@@H](c2c(Cl)cccc2Cl)C(C)C)CC1 by removing a benzene_ring.,CNC(=O)CN1CCC([NH2+][C@@H](c2c(Cl)cccc2Cl)C(C)C)CC1,benzene_ring876105500,Please remove a benzene_ring from the molecule COc1cc(CN(C)C[C@H](O)CN2CCOCC2)cc(Br)c1O.,COc1cc(CN(C)C[C@H](O)CN2CCOCC2)cc(Br)c1O,benzene_ring87789300,Please remove a amide from the molecule COC(=O)CN(C(=O)c1cnc([C@@H]2CCCO2)s1)c1cccc(F)c1.,COC(=O)CN(C(=O)c1cnc([C@@H]2CCCO2)s1)c1cccc(F)c1,amide8788140,Remove a amine from the molecule Cc1ccc(NC(=O)[C@@H](Sc2nnc(-c3cccnc3)n2N)c2ccccc2)cc1.,Cc1ccc(NC(=O)[C@@H](Sc2nnc(-c3cccnc3)n2N)c2ccccc2)cc1,amine879130924,Please remove a amide from the molecule Cn1c(-c2ccccn2)nn(CCNC(=O)c2ccco2)c1=O.,Cn1c(-c2ccccn2)nn(CCNC(=O)c2ccco2)c1=O,amide88093496,Please remove a benzene_ring from the molecule Cc1ccc([C@@H]2C3=C([O-])CCCC3=NC3=NC(SCC(=O)NCc4ccccc4)=NC(=O)[C@H]32)cc1.,Cc1ccc([C@@H]2C3=C([O-])CCCC3=NC3=NC(SCC(=O)NCc4ccccc4)=NC(=O)[C@H]32)cc1,benzene_ring881218148,Modify the molecule COc1ccc(OC)c(NC(=O)[C@H]2C[C@H](CCSC)N[C@]23C(=O)Nc2c(C)cc(Cl)cc23)c1 by removing a amine.,COc1ccc(OC)c(NC(=O)[C@H]2C[C@H](CCSC)N[C@]23C(=O)Nc2c(C)cc(Cl)cc23)c1,amine88254295,Please remove a halo from the molecule OC[C@H]1C[C@@H]1c1ccccc1Cl.,OC[C@H]1C[C@@H]1c1ccccc1Cl,halo88373447,Modify the molecule C[C@H]1CCC[C@H](C)C1NC(=O)/C=C/c1ccc(N2CCCS2(=O)=O)cc1 by removing a amide.,C[C@H]1CCC[C@H](C)C1NC(=O)/C=C/c1ccc(N2CCCS2(=O)=O)cc1,amide88447742,Please remove a halo from the molecule CCc1nc(CC[NH2+]Cc2cc(=O)c3cc(F)ccc3[nH]2)cs1.,CCc1nc(CC[NH2+]Cc2cc(=O)c3cc(F)ccc3[nH]2)cs1,halo88559428,Modify the molecule CC(=O)N1C=Cc2ccccc2[C@H]1CC(=O)NC[C@H](CC(C)C)[NH+](C)C by removing a amide.,CC(=O)N1C=Cc2ccccc2[C@H]1CC(=O)NC[C@H](CC(C)C)[NH+](C)C,amide88655436,Please remove a benzene_ring from the molecule C[C@@H](C(=O)N(C)C1CCCCC1)n1nnc(-c2ccccc2)n1.,C[C@@H](C(=O)N(C)C1CCCCC1)n1nnc(-c2ccccc2)n1,benzene_ring887174828,Please remove a amine from the molecule CCCN[C@@]1(C(=O)[O-])CC[C@H]([NH+]2CCC[C@@H]2C)C1.,CCCN[C@@]1(C(=O)[O-])CC[C@H]([NH+]2CCC[C@@H]2C)C1,amine888233722,Please remove a halo from the molecule C[C@H](SCc1ccnn1C)c1ccc(F)c(F)c1.,C[C@H](SCc1ccnn1C)c1ccc(F)c(F)c1,halo889111672,Please remove a benzene_ring from the molecule COc1cc(OC)cc([C@@H]2CCN(C(=O)N[C@@H]3C[C@@H]3c3ccccc3)C2)c1.,COc1cc(OC)cc([C@@H]2CCN(C(=O)N[C@@H]3C[C@@H]3c3ccccc3)C2)c1,benzene_ring890112674,Please remove a benzene_ring from the molecule COc1cc2c(cc1OC)C[NH+](Cn1nc(-c3ccc(Cl)cc3)n(C)c1=S)CC2.,COc1cc2c(cc1OC)C[NH+](Cn1nc(-c3ccc(Cl)cc3)n(C)c1=S)CC2,benzene_ring8911518,Remove a amide from the molecule CCc1nc(C)sc1CNC(=O)CCc1nc(-c2ccccc2C)no1.,CCc1nc(C)sc1CNC(=O)CCc1nc(-c2ccccc2C)no1,amide892114196,Please remove a amide from the molecule Cc1ccc(S(=O)(=O)[C@H](C)C(=O)Nc2c(C)cccc2C)cc1C.,Cc1ccc(S(=O)(=O)[C@H](C)C(=O)Nc2c(C)cccc2C)cc1C,amide89350658,Modify the molecule Cc1ccc(N2CC[C@H](Nc3ccc([N+](=O)[O-])nc3)C2=O)cc1 by removing a benzene_ring.,Cc1ccc(N2CC[C@H](Nc3ccc([N+](=O)[O-])nc3)C2=O)cc1,benzene_ring89426161,Remove a nitrile from the molecule CC(C)[C@@H](NC(=O)/C=C/c1ccc(OCC#N)cc1)c1ccccn1.,CC(C)[C@@H](NC(=O)/C=C/c1ccc(OCC#N)cc1)c1ccccn1,nitrile895201943,Remove a hydroxyl from the molecule C[C@H](C/C(N)=N/O)N1CC[NH+]2CCC[C@@H]2C1.,C[C@H](C/C(N)=N/O)N1CC[NH+]2CCC[C@@H]2C1,hydroxyl896172184,Remove a benzene_ring from the molecule Cc1nc(CNc2ccccc2OC[C@H]2CCCCO2)sc1C.,Cc1nc(CNc2ccccc2OC[C@H]2CCCCO2)sc1C,benzene_ring89761402,Modify the molecule COc1cccc([C@@H](CNC(=O)Nc2ccc(C(N)=O)c(C)c2)[NH+](C)C)c1 by removing a benzene_ring.,COc1cccc([C@@H](CNC(=O)Nc2ccc(C(N)=O)c(C)c2)[NH+](C)C)c1,benzene_ring898135923,Please remove a amide from the molecule CC(C)(C)c1ncc(NC(=O)Cc2csc(-c3cnccn3)n2)cn1.,CC(C)(C)c1ncc(NC(=O)Cc2csc(-c3cnccn3)n2)cn1,amide899158957,Modify the molecule O=C(NCCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)Nc1ccccc1 by removing a halo.,O=C(NCCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)Nc1ccccc1,halo900179455,Remove a benzene_ring from the molecule Cc1n[nH]c(SCCC(=O)NCc2ccc(N(C)C)cc2C)n1.,Cc1n[nH]c(SCCC(=O)NCc2ccc(N(C)C)cc2C)n1,benzene_ring901131661,Please remove a amide from the molecule Cc1cc(C(=O)NCCCSc2nccs2)c(C)o1.,Cc1cc(C(=O)NCCCSc2nccs2)c(C)o1,amide90254088,Remove a benzene_ring from the molecule COc1ccc(C[C@H]([NH3+])Cc2ccc(O)cc2)cn1.,COc1ccc(C[C@H]([NH3+])Cc2ccc(O)cc2)cn1,benzene_ring903165631,Please remove a amide from the molecule O=C(N[C@@H](C(=O)N/N=C\C=C\c1ccccc1)c1n[nH]c(=O)c2ccccc12)c1ccccc1.,O=C(N[C@@H](C(=O)N/N=C\C=C\c1ccccc1)c1n[nH]c(=O)c2ccccc12)c1ccccc1,amide90412069,Modify the molecule C[NH+]1CCN(C[C@@H](O)COc2cccc(C[NH3+])c2)CC1 by removing a benzene_ring.,C[NH+]1CCN(C[C@@H](O)COc2cccc(C[NH3+])c2)CC1,benzene_ring90538815,Please remove a benzene_ring from the molecule CC[NH2+][C@@H](C(C)C)[C@H](C)c1cc(C)ccc1C.,CC[NH2+][C@@H](C(C)C)[C@H](C)c1cc(C)ccc1C,benzene_ring906208100,Modify the molecule CCCc1cc(NC(=O)N(C)Cc2ccc(F)cc2Cl)n(C)n1 by removing a halo.,CCCc1cc(NC(=O)N(C)Cc2ccc(F)cc2Cl)n(C)n1,halo9071927,Remove a amide from the molecule Cc1nc(-c2cccc(Cl)c2)sc1C(=O)N[C@H]1CC[C@@H]([NH+](C)C)C1.,Cc1nc(-c2cccc(Cl)c2)sc1C(=O)N[C@H]1CC[C@@H]([NH+](C)C)C1,amide908162996,Modify the molecule COc1ccc(CN2CC[NH+](Cc3cccc(C)c3)CC2)cc1Br by removing a benzene_ring.,COc1ccc(CN2CC[NH+](Cc3cccc(C)c3)CC2)cc1Br,benzene_ring909114197,Modify the molecule CCn1nc(C)c(NC(=O)C[C@H]2Oc3ccccc3NC2=O)c1C by removing a amide.,CCn1nc(C)c(NC(=O)C[C@H]2Oc3ccccc3NC2=O)c1C,amide91076779,Remove a amide from the molecule CCc1nn(C)cc1NC(=O)CCn1c(C)csc1=O.,CCc1nn(C)cc1NC(=O)CCn1c(C)csc1=O,amide91135000,Remove a amide from the molecule COC(CNC(=O)CN1CC[NH2+]CC1)OC.,COC(CNC(=O)CN1CC[NH2+]CC1)OC,amide912140664,Modify the molecule Cc1cc(C)cc(O[C@@H](C)C(=O)N(Cc2ccc(F)cc2)[C@@H]2CCS(=O)(=O)C2)c1 by removing a halo.,Cc1cc(C)cc(O[C@@H](C)C(=O)N(Cc2ccc(F)cc2)[C@@H]2CCS(=O)(=O)C2)c1,halo91388597,Please remove a benzene_ring from the molecule O=C(NCC[NH+]1CCC(c2ccsc2)CC1)c1ccc(F)cc1Cl.,O=C(NCC[NH+]1CCC(c2ccsc2)CC1)c1ccc(F)cc1Cl,benzene_ring914196700,Remove a amide from the molecule Cc1cc(C)cc(-n2cc(C(=O)N3CCC(C)CC3)nn2)c1.,Cc1cc(C)cc(-n2cc(C(=O)N3CCC(C)CC3)nn2)c1,amide915167343,Remove a amine from the molecule COc1ccc(/C=[NH+]\C[C@H]2COc3ccccc3O2)c(OC)c1.,COc1ccc(/C=[NH+]\C[C@H]2COc3ccccc3O2)c(OC)c1,amine916238279,Remove a benzene_ring from the molecule CO[C@H]1CCCN(C(=O)N[C@@H](C)c2cnn(-c3ccccc3)c2C)C1.,CO[C@H]1CCCN(C(=O)N[C@@H](C)c2cnn(-c3ccccc3)c2C)C1,benzene_ring917149280,Remove a amide from the molecule Cc1cc(C)c(C[S@](=O)CC(=O)N(C)c2ccccc2)c(C)c1.,Cc1cc(C)c(C[S@](=O)CC(=O)N(C)c2ccccc2)c(C)c1,amide918186507,Remove a halo from the molecule Cc1ccc(-n2c([C@H](C)Cl)nc3cc(C)cnc32)c(C)c1.,Cc1ccc(-n2c([C@H](C)Cl)nc3cc(C)cnc32)c(C)c1,halo919148771,Please remove a benzene_ring from the molecule C[C@H](CN(C(=O)c1ccoc1)c1ccccc1)NC(=O)c1ccoc1.,C[C@H](CN(C(=O)c1ccoc1)c1ccccc1)NC(=O)c1ccoc1,benzene_ring92012561,Remove a benzene_ring from the molecule Cc1ccc(-n2cnnn2)cc1NC(=O)[C@@H]1C=C[C@@H]([NH3+])C1.,Cc1ccc(-n2cnnn2)cc1NC(=O)[C@@H]1C=C[C@@H]([NH3+])C1,benzene_ring921119261,Please remove a amide from the molecule CCOC[C@@H]1CCN(C(=O)[C@@H](C)Sc2nnnn2C2CC2)C1.,CCOC[C@@H]1CCN(C(=O)[C@@H](C)Sc2nnnn2C2CC2)C1,amide922180592,Please remove a amide from the molecule Cc1cc(NC(=O)CSc2nnnn2C2CCCC2)n(-c2ccccc2)n1.,Cc1cc(NC(=O)CSc2nnnn2C2CCCC2)n(-c2ccccc2)n1,amide9234571,Please remove a benzene_ring from the molecule Cc1ccc(C(=O)[C@H]2CSCCS2)cc1C.,Cc1ccc(C(=O)[C@H]2CSCCS2)cc1C,benzene_ring924138682,Modify the molecule C[NH2+]Cc1ccccc1NC(=O)C1C(C)(C)C1(C)C by removing a benzene_ring.,C[NH2+]Cc1ccccc1NC(=O)C1C(C)(C)C1(C)C,benzene_ring925216572,Remove a amide from the molecule O=C(c1ccc([C@H]2CCC[NH2+]2)s1)N1CCC(CN2CCOCC2)CC1.,O=C(c1ccc([C@H]2CCC[NH2+]2)s1)N1CCC(CN2CCOCC2)CC1,amide926204546,Remove a amide from the molecule CCC(=O)N1CCC[C@H](COc2ccc(C(=O)N3CCCCC3)cc2)C1.,CCC(=O)N1CCC[C@H](COc2ccc(C(=O)N3CCCCC3)cc2)C1,amide92751575,Modify the molecule CC(C)[C@@H](NC(=O)C(=O)Nc1ccc2c(c1)CCC(=O)N2)c1ccccc1 by removing a amide.,CC(C)[C@@H](NC(=O)C(=O)Nc1ccc2c(c1)CCC(=O)N2)c1ccccc1,amide92819780,Remove a benzene_ring from the molecule Cc1ccc(S[C@H]2CSc3nc(C)cc(=O)n3[C@@H]2c2ccccc2)cc1.,Cc1ccc(S[C@H]2CSc3nc(C)cc(=O)n3[C@@H]2c2ccccc2)cc1,benzene_ring92924317,Modify the molecule C[C@@H]1C(=O)CCN(c2ccc(F)cc2F)[C@H]1C by removing a benzene_ring.,C[C@@H]1C(=O)CCN(c2ccc(F)cc2F)[C@H]1C,benzene_ring930173479,Please remove a amide from the molecule CCN(C(=O)Cc1ccc(F)c(F)c1)[C@@H]1CCC[C@H]1C[NH3+].,CCN(C(=O)Cc1ccc(F)c(F)c1)[C@@H]1CCC[C@H]1C[NH3+],amide9316403,Modify the molecule O=C(NC[C@@H]1CC[NH+](Cc2cccc(O)c2)C1)c1cc2ccccc2[nH]1 by removing a amide.,O=C(NC[C@@H]1CC[NH+](Cc2cccc(O)c2)C1)c1cc2ccccc2[nH]1,amide932137534,Please remove a amine from the molecule Cc1c(F)cccc1-c1ccc(CN[C@@H](CO)c2ccco2)o1.,Cc1c(F)cccc1-c1ccc(CN[C@@H](CO)c2ccco2)o1,amine93371341,Modify the molecule Cc1ccccc1C[NH2+]CC1CC[NH2+]CC1 by removing a benzene_ring.,Cc1ccccc1C[NH2+]CC1CC[NH2+]CC1,benzene_ring93434245,Remove a amide from the molecule Cc1cccc(C)c1N1CCN(C(=O)c2ccccc2Cl)CC1.,Cc1cccc(C)c1N1CCN(C(=O)c2ccccc2Cl)CC1,amide93518884,Modify the molecule COc1ccc(O)c([C@H](C)NC(=O)Nc2cccc(C)c2Cl)c1 by removing a hydroxyl.,COc1ccc(O)c([C@H](C)NC(=O)Nc2cccc(C)c2Cl)c1,hydroxyl9368154,Please remove a hydroxyl from the molecule COc1cc(CN2CCC([NH+]3CCC[C@@H]3C)CC2)cc([N+](=O)[O-])c1O.,COc1cc(CN2CCC([NH+]3CCC[C@@H]3C)CC2)cc([N+](=O)[O-])c1O,hydroxyl93719498,Remove a amide from the molecule Cc1nnc2ccc(C(=O)N3CCCCC[C@H]3c3cccn3C)cn12.,Cc1nnc2ccc(C(=O)N3CCCCC[C@H]3c3cccn3C)cn12,amide93864782,Modify the molecule OCC[NH+]1CCN(C(=S)NCc2ccco2)CC1 by removing a amine.,OCC[NH+]1CCN(C(=S)NCc2ccco2)CC1,amine93988735,Please remove a nitrile from the molecule C[C@H]1CO[C@@H](c2ccccc2)[C@H](C)N1Cc1cnc2ccc(C#N)cn12.,C[C@H]1CO[C@@H](c2ccccc2)[C@H](C)N1Cc1cnc2ccc(C#N)cn12,nitrile940128684,Modify the molecule C[C@H]1CCCC[C@H]1NC(=O)C(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 by removing a halo.,C[C@H]1CCCC[C@H]1NC(=O)C(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1,halo941152276,Modify the molecule C[C@@H](C(=O)NCc1ccc(F)cc1)C1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1 by removing a benzene_ring.,C[C@@H](C(=O)NCc1ccc(F)cc1)C1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1,benzene_ring94215721,Please remove a halo from the molecule COc1ccc(S(=O)(=O)NC[C@@H]2CCN(c3ccc(F)c(F)c3)C2)cc1C.,COc1ccc(S(=O)(=O)NC[C@@H]2CCN(c3ccc(F)c(F)c3)C2)cc1C,halo943216083,Modify the molecule Cc1nnc2ccc(Nc3ccc4oc(=O)n(CC[NH+](C)C)c4c3)nn12 by removing a amine.,Cc1nnc2ccc(Nc3ccc4oc(=O)n(CC[NH+](C)C)c4c3)nn12,amine94452058,Please remove a benzene_ring from the molecule Nc1ccc(CCNC(=O)Cc2ccc(F)c(F)c2)cc1.,Nc1ccc(CCNC(=O)Cc2ccc(F)c(F)c2)cc1,benzene_ring945220510,Remove a amide from the molecule COc1ccccc1C[NH+]1CCC(Oc2ccc(C(=O)NC3CCCC3)cc2Cl)CC1.,COc1ccccc1C[NH+]1CCC(Oc2ccc(C(=O)NC3CCCC3)cc2Cl)CC1,amide946186841,Modify the molecule CCCC(=O)N1CCC[C@@H](C(=O)N[C@H]2C[C@H]2CCC)C1 by removing a amide.,CCCC(=O)N1CCC[C@@H](C(=O)N[C@H]2C[C@H]2CCC)C1,amide947171856,Remove a amide from the molecule CCCOc1ccc(NC(=O)CNC(C)=O)cc1Cl.,CCCOc1ccc(NC(=O)CNC(C)=O)cc1Cl,amide94838876,Please remove a benzene_ring from the molecule Cc1[nH]c(=O)c(C(=O)OC[C@@H]2C[C@H]2C)cc1-c1ccccc1.,Cc1[nH]c(=O)c(C(=O)OC[C@@H]2C[C@H]2C)cc1-c1ccccc1,benzene_ring949119552,Modify the molecule O=C(NCc1ccc(Cl)cc1)c1ccc(CNc2c(O)c(=O)c2=[N+]2CCCCC2)cc1 by removing a amine.,O=C(NCc1ccc(Cl)cc1)c1ccc(CNc2c(O)c(=O)c2=[N+]2CCCCC2)cc1,amine950210836,Please remove a amide from the molecule CC(C)N(Cc1cccnc1)C(=O)CN1C(=O)[C@@H]2CCCC[C@H]2C1=O.,CC(C)N(Cc1cccnc1)C(=O)CN1C(=O)[C@@H]2CCCC[C@H]2C1=O,amide951239779,Modify the molecule O=C([O-])c1cncc(Nc2ccc(Cl)cc2C(F)(F)F)n1 by removing a halo.,O=C([O-])c1cncc(Nc2ccc(Cl)cc2C(F)(F)F)n1,halo952181976,Modify the molecule CC[C@H]1CC[NH+](Cc2cc(Cl)ccc2O)C1 by removing a halo.,CC[C@H]1CC[NH+](Cc2cc(Cl)ccc2O)C1,halo953138514,Remove a amine from the molecule CNC(=S)Nc1n[nH]c(SC)n1.,CNC(=S)Nc1n[nH]c(SC)n1,amine954248091,Please remove a amide from the molecule O=C(C1=C[C@H]2N=CC=C2C=C1)N(Cc1cccnc1)CC1CC[NH+](C2CCCC2)CC1.,O=C(C1=C[C@H]2N=CC=C2C=C1)N(Cc1cccnc1)CC1CC[NH+](C2CCCC2)CC1,amide955200254,Remove a halo from the molecule CC[C@H]1CCC(=O)[C@H](Cc2cc(Cl)ccc2[N+](=O)[O-])C1.,CC[C@H]1CCC(=O)[C@H](Cc2cc(Cl)ccc2[N+](=O)[O-])C1,halo95615183,Modify the molecule CCOC(=O)C1=C(N)Oc2cc(C)n(CC[NH+](C)C)c(=O)c2[C@H]1c1ccc(Cl)cc1 by removing a amine.,CCOC(=O)C1=C(N)Oc2cc(C)n(CC[NH+](C)C)c(=O)c2[C@H]1c1ccc(Cl)cc1,amine95767270,Please remove a benzene_ring from the molecule Cc1ccc([S@@](=O)[C@H]2CCC(C)(C)[C@@H]2[NH3+])cc1C.,Cc1ccc([S@@](=O)[C@H]2CCC(C)(C)[C@@H]2[NH3+])cc1C,benzene_ring958190042,Remove a benzene_ring from the molecule O=C(NC(=S)N1CCOCC1)c1ccccc1C(=O)OCC(F)(F)F.,O=C(NC(=S)N1CCOCC1)c1ccccc1C(=O)OCC(F)(F)F,benzene_ring959135199,Please remove a amide from the molecule Cn1cccc(NC(=O)C(=O)N2CC[C@@H](Cc3ccccc3)C2)c1=O.,Cn1cccc(NC(=O)C(=O)N2CC[C@@H](Cc3ccccc3)C2)c1=O,amide96021721,Please remove a amide from the molecule Cc1nc(CN(C)C(=O)[C@@H]2CC[NH2+][C@H]2C)n[nH]1.,Cc1nc(CN(C)C(=O)[C@@H]2CC[NH2+][C@H]2C)n[nH]1,amide96189615,Remove a benzene_ring from the molecule CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccc([C@H]3C[C@@H]3C)o2)cc1.,CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccc([C@H]3C[C@@H]3C)o2)cc1,benzene_ring962145981,Modify the molecule Cc1cc(C)c2c3ccccc3n(CCNC(=O)c3cccc4cccnc34)c2n1 by removing a amide.,Cc1cc(C)c2c3ccccc3n(CCNC(=O)c3cccc4cccnc34)c2n1,amide963239626,Remove a amide from the molecule COc1cc2c(cc1OC)[C@@]1(Cc3ccc(Cl)cc3)[C@@H]3CC=CC[C@@H]3C(=O)N1CC2.,COc1cc2c(cc1OC)[C@@]1(Cc3ccc(Cl)cc3)[C@@H]3CC=CC[C@@H]3C(=O)N1CC2,amide964177278,Remove a amide from the molecule C=CCN1C[C@H](C(=O)Cl)CC1=O.,C=CCN1C[C@H](C(=O)Cl)CC1=O,amide965245779,Remove a benzene_ring from the molecule Cc1ccc(-c2ccc(=O)n(Cc3noc(C(=O)N4CCCC4)n3)n2)cc1C.,Cc1ccc(-c2ccc(=O)n(Cc3noc(C(=O)N4CCCC4)n3)n2)cc1C,benzene_ring966160211,Modify the molecule NS(=O)(=O)CCN(CCO)Cc1cc(Br)ccc1F by removing a halo.,NS(=O)(=O)CCN(CCO)Cc1cc(Br)ccc1F,halo967133449,Modify the molecule COc1ccc([C@@H](C)[C@H](C)[NH2+]C2CCN(S(=O)(=O)C3CC3)CC2)cc1 by removing a benzene_ring.,COc1ccc([C@@H](C)[C@H](C)[NH2+]C2CCN(S(=O)(=O)C3CC3)CC2)cc1,benzene_ring96876853,Remove a benzene_ring from the molecule c1ccc(-c2cc(N3CCC[C@@H](Cn4cc[nH+]c4)C3)n3nccc3n2)cc1.,c1ccc(-c2cc(N3CCC[C@@H](Cn4cc[nH+]c4)C3)n3nccc3n2)cc1,benzene_ring96964542,Remove a amide from the molecule C[C@@H](NC(=O)CN1CCCC1=O)c1cccc2ccccc12.,C[C@@H](NC(=O)CN1CCCC1=O)c1cccc2ccccc12,amide97049854,Modify the molecule O=C(Nc1ccc(OC(F)F)cc1)[C@@H]1CCCCN1S(=O)(=O)c1ccccc1 by removing a amide.,O=C(Nc1ccc(OC(F)F)cc1)[C@@H]1CCCCN1S(=O)(=O)c1ccccc1,amide97172889,Remove a amine from the molecule Cc1nnc2ccc(N[C@H](C)C(=O)N3CCOCC3)nn12.,Cc1nnc2ccc(N[C@H](C)C(=O)N3CCOCC3)nn12,amine972217840,Please remove a amine from the molecule O=[N+]([O-])c1cccnc1N[C@H]1c2ccccc2C[C@H]1O.,O=[N+]([O-])c1cccnc1N[C@H]1c2ccccc2C[C@H]1O,amine973154132,Please remove a halo from the molecule Cc1nn(C(=O)OC(C)(C)C)c(C)c1Br.,Cc1nn(C(=O)OC(C)(C)C)c(C)c1Br,halo974109418,Modify the molecule C[C@H]1C[NH+]2CCC[C@@H]2CN1c1cc(Cl)ccc1C(=O)[O-] by removing a benzene_ring.,C[C@H]1C[NH+]2CCC[C@@H]2CN1c1cc(Cl)ccc1C(=O)[O-],benzene_ring975100088,Remove a amide from the molecule C=CC(=O)N[C@@H](C)c1nc2ccccc2n1C.,C=CC(=O)N[C@@H](C)c1nc2ccccc2n1C,amide976186730,Modify the molecule CCN(C[C@@H](C)C#N)C(=O)Nc1c(C(C)C)cccc1C(C)C by removing a benzene_ring.,CCN(C[C@@H](C)C#N)C(=O)Nc1c(C(C)C)cccc1C(C)C,benzene_ring977125743,Remove a amide from the molecule O=C(CC1(O)CCCC1)NCc1cn2cc(Br)ccc2n1.,O=C(CC1(O)CCCC1)NCc1cn2cc(Br)ccc2n1,amide978163840,Please remove a nitrile from the molecule N#C[C@H]1C(=O)NC(=S)[C@@H](C(N)=O)C12CCCCC2.,N#C[C@H]1C(=O)NC(=S)[C@@H](C(N)=O)C12CCCCC2,nitrile97997706,Modify the molecule COC(=O)c1cc2n(n1)CCN(C(=O)c1cc(-c3ccccc3O)n[nH]1)C2 by removing a amide.,COC(=O)c1cc2n(n1)CCN(C(=O)c1cc(-c3ccccc3O)n[nH]1)C2,amide98046258,Modify the molecule C[C@@H]1C[C@H]1N1C[C@H](NC(=O)Cc2cccc(O)c2)CC1=O by removing a amide.,C[C@@H]1C[C@H]1N1C[C@H](NC(=O)Cc2cccc(O)c2)CC1=O,amide98135311,Please remove a benzene_ring from the molecule CS(=O)(=O)c1ccccc1C(=O)Nc1nc(-c2ccc([N+](=O)[O-])cc2)cs1.,CS(=O)(=O)c1ccccc1C(=O)Nc1nc(-c2ccc([N+](=O)[O-])cc2)cs1,benzene_ring982175858,Please remove a benzene_ring from the molecule CC[C@H]1CCN(C(=O)Nc2cccc(CS(=O)(=O)N[C@H](C)CC)c2)C1.,CC[C@H]1CCN(C(=O)Nc2cccc(CS(=O)(=O)N[C@H](C)CC)c2)C1,benzene_ring983206081,Please remove a halo from the molecule CC[NH+](CCC(=O)Nc1ccc(F)cc1N)C(C)C.,CC[NH+](CCC(=O)Nc1ccc(F)cc1N)C(C)C,halo984113735,Modify the molecule CCc1cccc(NC(=O)c2cc(C)c(C#CCO)s2)c1 by removing a amide.,CCc1cccc(NC(=O)c2cc(C)c(C#CCO)s2)c1,amide98554729,Remove a amide from the molecule N/C(=N/OCC(=O)N1CCCCCCC1)c1cnccn1.,N/C(=N/OCC(=O)N1CCCCCCC1)c1cnccn1,amide98673946,Remove a hydroxyl from the molecule C/C(=N\O)[C@H]1C[C@H]2C=C(C#N)[C@@H]1[NH+](Cc1ccccc1)C2.,C/C(=N\O)[C@H]1C[C@H]2C=C(C#N)[C@@H]1[NH+](Cc1ccccc1)C2,hydroxyl987134512,Remove a amide from the molecule C[C@@H]1CCC[C@H]1[NH2+]CCNC(=O)CC1CCCCC1.,C[C@@H]1CCC[C@H]1[NH2+]CCNC(=O)CC1CCCCC1,amide98864649,Remove a benzene_ring from the molecule COc1ccc(-n2cnc3c2N=C(O)C[C@H]3c2ccc(F)cc2)cc1.,COc1ccc(-n2cnc3c2N=C(O)C[C@H]3c2ccc(F)cc2)cc1,benzene_ring98940047,Modify the molecule COc1ccc(NC(=S)NC(=O)C2CCC2)cc1 by removing a amine.,COc1ccc(NC(=S)NC(=O)C2CCC2)cc1,amine990149344,Please remove a amide from the molecule CCOC(=O)[C@H]1C[NH2+]C[C@]12COc1ccccc1C(=O)N2.,CCOC(=O)[C@H]1C[NH2+]C[C@]12COc1ccccc1C(=O)N2,amide991177583,Modify the molecule Cc1occc1C(=O)NCC(=O)NC[C@@H](C)c1nc(-c2ccccc2)no1 by removing a benzene_ring.,Cc1occc1C(=O)NCC(=O)NC[C@@H](C)c1nc(-c2ccccc2)no1,benzene_ring992238478,Please remove a amide from the molecule CC(C)c1ccc2cc(C(=O)N(C)Cc3ccc(Br)o3)[nH]c2c1.,CC(C)c1ccc2cc(C(=O)N(C)Cc3ccc(Br)o3)[nH]c2c1,amide993175797,Please remove a benzene_ring from the molecule Cc1ccc(COc2ccc(-c3nnco3)cc2)cc1.,Cc1ccc(COc2ccc(-c3nnco3)cc2)cc1,benzene_ring994168043,Modify the molecule COc1cc(C(C)=O)ccc1OCC(=O)NC1C[C@@H]2CCC[C@H](C1)[NH+]2C by removing a benzene_ring.,COc1cc(C(C)=O)ccc1OCC(=O)NC1C[C@@H]2CCC[C@H](C1)[NH+]2C,benzene_ring99579043,Modify the molecule CC(C)C[NH+]1CCN(Cn2nnn(-c3ccc(Cl)cc3)c2=S)CC1 by removing a benzene_ring.,CC(C)C[NH+]1CCN(Cn2nnn(-c3ccc(Cl)cc3)c2=S)CC1,benzene_ring996170692,Modify the molecule C[NH2+]Cc1ccccc1O[C@@H](C)C(=O)NC(N)=O by removing a amide.,C[NH2+]Cc1ccccc1O[C@@H](C)C(=O)NC(N)=O,amide99761582,Please remove a nitro from the molecule CCNC(=O)C(=O)N/N=C\c1cc([N+](=O)[O-])ccc1[O-].,CCNC(=O)C(=O)N/N=C\c1cc([N+](=O)[O-])ccc1[O-],nitro998103178,Please remove a benzene_ring from the molecule CCCc1ccc(OCc2cnc(N)s2)cc1.,CCCc1ccc(OCc2cnc(N)s2)cc1,benzene_ring999107466,Modify the molecule COc1ccnc(NC(=O)[C@@H](C)c2ccc(Br)s2)c1 by removing a halo.,COc1ccnc(NC(=O)[C@@H](C)c2ccc(Br)s2)c1,halo1000174546,Remove a halo from the molecule [NH2+]=c1oc2ccc(Br)cc2cc1C(=O)NCc1cccnc1.,[NH2+]=c1oc2ccc(Br)cc2cc1C(=O)NCc1cccnc1,halo1001223533,Remove a amide from the molecule C[C@H](NC(=O)CCn1ccccc1=O)C(=O)[O-].,C[C@H](NC(=O)CCn1ccccc1=O)C(=O)[O-],amide1002201022,Modify the molecule O[C@H]1CCCC[C@H]1Sc1nnc(-c2ccc(Cl)s2)o1 by removing a halo.,O[C@H]1CCCC[C@H]1Sc1nnc(-c2ccc(Cl)s2)o1,halo100326235,Please remove a amide from the molecule CC[NH+](C)CC(=O)NC[C@H]1CN(CC(C)C)CCO1.,CC[NH+](C)CC(=O)NC[C@H]1CN(CC(C)C)CCO1,amide100422265,Remove a amide from the molecule O=C([O-])COCC(=O)Nc1ccc2c(c1)CCCC2.,O=C([O-])COCC(=O)Nc1ccc2c(c1)CCCC2,amide100536182,Modify the molecule O=C(Nc1ccnn1Cc1cccc2ccccc12)c1cccnc1Cl by removing a amide.,O=C(Nc1ccnn1Cc1cccc2ccccc12)c1cccnc1Cl,amide100646096,Remove a amide from the molecule CCc1cc(=O)n2c(n1)SC[C@@H]2CC(=O)Nc1ccccc1OC.,CCc1cc(=O)n2c(n1)SC[C@@H]2CC(=O)Nc1ccccc1OC,amide100770190,Please remove a amide from the molecule CCC[C@@H](C)NC(=O)[C@@H]1CCCN(C(=O)Nc2ccc(C(=O)NC)cc2)C1.,CCC[C@@H](C)NC(=O)[C@@H]1CCCN(C(=O)Nc2ccc(C(=O)NC)cc2)C1,amide1008162466,Please remove a benzene_ring from the molecule CNc1ccc(C(=O)[O-])cc1C(=O)[O-].,CNc1ccc(C(=O)[O-])cc1C(=O)[O-],benzene_ring1009191171,Remove a halo from the molecule C/C(=C\c1ccc(F)cc1)C(=O)OC[C@H]1CCCO1.,C/C(=C\c1ccc(F)cc1)C(=O)OC[C@H]1CCCO1,halo1010131543,Please remove a benzene_ring from the molecule CN(C)c1ccc(C[C@H](C(N)=S)c2nc3ccccc3[nH]2)cc1.,CN(C)c1ccc(C[C@H](C(N)=S)c2nc3ccccc3[nH]2)cc1,benzene_ring1011141084,Modify the molecule CCn1c(=O)n(CC(=O)N2CCn3c(C)nnc3C2)c2ccccc21 by removing a amide.,CCn1c(=O)n(CC(=O)N2CCn3c(C)nnc3C2)c2ccccc21,amide101275068,Please remove a benzene_ring from the molecule CC(=O)N1CCc2ccccc2[C@H]1CC(=O)O[C@@H](C)c1cccc(F)c1.,CC(=O)N1CCc2ccccc2[C@H]1CC(=O)O[C@@H](C)c1cccc(F)c1,benzene_ring101339831,Remove a amide from the molecule O=C(Nc1cc(F)ccc1Cl)[C@@H](O)c1ccccc1.,O=C(Nc1cc(F)ccc1Cl)[C@@H](O)c1ccccc1,amide101497439,Modify the molecule CN(C)C(=O)c1cccc(S(=O)(=O)N2CCCc3cccc(F)c32)c1 by removing a benzene_ring.,CN(C)C(=O)c1cccc(S(=O)(=O)N2CCCc3cccc(F)c32)c1,benzene_ring1015203090,Please remove a amide from the molecule Cc1ccc([C@H]2[C@@H](C(=O)N[C@@H](C)c3nc4ccccc4o3)CCC(=O)N2C)cc1.,Cc1ccc([C@H]2[C@@H](C(=O)N[C@@H](C)c3nc4ccccc4o3)CCC(=O)N2C)cc1,amide1016232374,Please remove a amide from the molecule CCOc1ccc(-c2nc(C(=O)N3CCNC(=O)[C@@H]3CC)cs2)cc1.,CCOc1ccc(-c2nc(C(=O)N3CCNC(=O)[C@@H]3CC)cs2)cc1,amide101781903,Please remove a amide from the molecule C=CCN(C(=O)[C@@H]1CS[C@@]2(C)CCC(=O)N12)c1nc2c(s1)CCCC2.,C=CCN(C(=O)[C@@H]1CS[C@@]2(C)CCC(=O)N12)c1nc2c(s1)CCCC2,amide101889947,Remove a amine from the molecule CO[C@@H](C)/C(N)=N/OCCOC1CCCCCC1.,CO[C@@H](C)/C(N)=N/OCCOC1CCCCCC1,amine1019226041,Please remove a nitrile from the molecule C[C@@H](CC#N)N(C)C(=O)Nc1ccc(Cl)cc1F.,C[C@@H](CC#N)N(C)C(=O)Nc1ccc(Cl)cc1F,nitrile1020211269,Remove a halo from the molecule O=C(NCC[NH+]1CCC(CO)CC1)Nc1ccc(C(F)(F)F)cc1.,O=C(NCC[NH+]1CCC(CO)CC1)Nc1ccc(C(F)(F)F)cc1,halo1021118419,Remove a halo from the molecule Cc1cc(N(CCC(F)(F)F)CC2CC2)nc(-c2ccccn2)n1.,Cc1cc(N(CCC(F)(F)F)CC2CC2)nc(-c2ccccn2)n1,halo102297248,Please remove a benzene_ring from the molecule NC(=O)N1CCC[C@H](C(=O)Nc2cccc(-c3nc4ccccc4s3)c2)C1.,NC(=O)N1CCC[C@H](C(=O)Nc2cccc(-c3nc4ccccc4s3)c2)C1,benzene_ring1023115897,Remove a amide from the molecule CC(=O)c1cccc(OCC2=C[C@@H](C(=O)NCc3ccco3)N=N2)c1.,CC(=O)c1cccc(OCC2=C[C@@H](C(=O)NCc3ccco3)N=N2)c1,amide1024170866,Please remove a benzene_ring from the molecule CCCNc1ncnc(Nc2ccc(I)cc2)c1[N+](=O)[O-].,CCCNc1ncnc(Nc2ccc(I)cc2)c1[N+](=O)[O-],benzene_ring102588810,Please remove a amide from the molecule CCc1ccc([C@H](COC)NC(=O)C(=O)Nc2ccc3ncccc3c2)o1.,CCc1ccc([C@H](COC)NC(=O)C(=O)Nc2ccc3ncccc3c2)o1,amide1026158687,Remove a nitrile from the molecule C=C(C)COc1nc(C)c2c(c1C#N)CC(C)(C)OC2.,C=C(C)COc1nc(C)c2c(c1C#N)CC(C)(C)OC2,nitrile1027246241,Remove a hydroxyl from the molecule O=C([O-])C[C@](O)(c1ccco1)C(F)(F)F.,O=C([O-])C[C@](O)(c1ccco1)C(F)(F)F,hydroxyl102835330,Remove a amine from the molecule CCOc1ccc(S(=O)(=O)NCc2ccco2)cc1C(C)C.,CCOc1ccc(S(=O)(=O)NCc2ccco2)cc1C(C)C,amine102918900,Please remove a amine from the molecule CCn1nc(C(=O)N2CCCC2)c2c1CC[C@@H](NCc1nc(-c3ccccc3)cs1)C2.,CCn1nc(C(=O)N2CCCC2)c2c1CC[C@@H](NCc1nc(-c3ccccc3)cs1)C2,amine10306101,Remove a benzene_ring from the molecule CC[NH2+][C@]1(C(=O)[O-])CCC[C@@H]1CCSc1ccc(C)cc1.,CC[NH2+][C@]1(C(=O)[O-])CCC[C@@H]1CCSc1ccc(C)cc1,benzene_ring1031156633,Modify the molecule CCc1noc(C)c1C(=O)Nc1ccc(Cl)cc1C(F)(F)F by removing a halo.,CCc1noc(C)c1C(=O)Nc1ccc(Cl)cc1C(F)(F)F,halo103255822,Modify the molecule CC1(C)CN(C(=O)Cc2ccc(C(F)(F)F)cc2)CC[S@]1=O by removing a halo.,CC1(C)CN(C(=O)Cc2ccc(C(F)(F)F)cc2)CC[S@]1=O,halo1033123318,Please remove a amine from the molecule COC1CCN(c2ccc(C(F)(F)F)cc2C(N)=[NH2+])CC1.,COC1CCN(c2ccc(C(F)(F)F)cc2C(N)=[NH2+])CC1,amine1034208230,Modify the molecule Cc1nn(C(C)C)c(C)c1S(=O)(=O)[N-]c1cccc(C(=O)[O-])c1C by removing a benzene_ring.,Cc1nn(C(C)C)c(C)c1S(=O)(=O)[N-]c1cccc(C(=O)[O-])c1C,benzene_ring1035228388,Please remove a halo from the molecule C[C@H](C(=O)N1CCCC1)N1CCN(c2ccc(Cl)c(C#N)n2)CC1.,C[C@H](C(=O)N1CCCC1)N1CCN(c2ccc(Cl)c(C#N)n2)CC1,halo103686092,Please remove a benzene_ring from the molecule CO/N=C/c1ccc(C(=O)N(C)[C@H](C)c2ccc([S@](C)=O)cc2)cc1.,CO/N=C/c1ccc(C(=O)N(C)[C@H](C)c2ccc([S@](C)=O)cc2)cc1,benzene_ring1037136241,Modify the molecule Cc1cc(CC(=O)NCCOc2c(C)cccc2C)no1 by removing a amide.,Cc1cc(CC(=O)NCCOc2c(C)cccc2C)no1,amide1038140901,Modify the molecule N#Cc1c(-c2ccc(F)cc2)cc(-c2ccccc2)nc1N by removing a nitrile.,N#Cc1c(-c2ccc(F)cc2)cc(-c2ccccc2)nc1N,nitrile1039116479,Modify the molecule CCO[C@@H]1CCCN(C(=O)c2nc(C(C)(C)C)n[nH]2)C1 by removing a amide.,CCO[C@@H]1CCCN(C(=O)c2nc(C(C)(C)C)n[nH]2)C1,amide1040187541,Modify the molecule Cc1ccccc1-c1cnc(CNN2CCCCC2)s1 by removing a benzene_ring.,Cc1ccccc1-c1cnc(CNN2CCCCC2)s1,benzene_ring1041132929,Modify the molecule Cc1c(Cl)cccc1-n1c(S[C@@H](C)C(N)=O)nc2ccccc2c1=O by removing a halo.,Cc1c(Cl)cccc1-n1c(S[C@@H](C)C(N)=O)nc2ccccc2c1=O,halo104244500,Modify the molecule CC[NH2+][C@@H](CCC(F)(F)F)[C@@H]1C[NH+]2CCN1CC2 by removing a halo.,CC[NH2+][C@@H](CCC(F)(F)F)[C@@H]1C[NH+]2CCN1CC2,halo1043191921,Modify the molecule COc1ccccc1[C@@H](O)[C@H](C)C#N by removing a benzene_ring.,COc1ccccc1[C@@H](O)[C@H](C)C#N,benzene_ring1044197986,Modify the molecule Cc1cc(F)cc([C@H]([NH3+])Cc2cccc(C(F)(F)F)c2)c1 by removing a benzene_ring.,Cc1cc(F)cc([C@H]([NH3+])Cc2cccc(C(F)(F)F)c2)c1,benzene_ring104586334,Modify the molecule CCOc1ccc(Cl)cc1/C=N/N1C(=O)[C@@H]2C3c4ccccc4C(c4ccccc43)[C@H]2C1=O by removing a benzene_ring.,CCOc1ccc(Cl)cc1/C=N/N1C(=O)[C@@H]2C3c4ccccc4C(c4ccccc43)[C@H]2C1=O,benzene_ring10462168,Modify the molecule CCn1cc[nH+]c1[C@@H]1CCCN(C(=O)CSCC[NH+]2CCCC2)C1 by removing a amide.,CCn1cc[nH+]c1[C@@H]1CCCN(C(=O)CSCC[NH+]2CCCC2)C1,amide1047235393,Please remove a amine from the molecule CC[NH+]1CCC[C@H]1CNC(=O)c1sc2ncnc(NCc3ccc4c(c3)OCO4)c2c1C.,CC[NH+]1CCC[C@H]1CNC(=O)c1sc2ncnc(NCc3ccc4c(c3)OCO4)c2c1C,amine1048244950,Please remove a amide from the molecule C[C@H](NC(=O)c1cccs1)C(=O)N1CCc2c(sc(N)c2C#N)C1.,C[C@H](NC(=O)c1cccs1)C(=O)N1CCc2c(sc(N)c2C#N)C1,amide1049125572,Modify the molecule O[C@]12CCCC[C@H]1[C@@H](Cc1cccnc1Cl)[NH2+]CC2 by removing a hydroxyl.,O[C@]12CCCC[C@H]1[C@@H](Cc1cccnc1Cl)[NH2+]CC2,hydroxyl1050220551,Remove a amide from the molecule CCc1ccccc1OCC(=O)NCc1cscn1.,CCc1ccccc1OCC(=O)NCc1cscn1,amide1051129812,Please remove a amide from the molecule CCCN(C(=O)Cn1ncc2c(=O)oc3ccccc3c21)c1ccc(OCC)cc1.,CCCN(C(=O)Cn1ncc2c(=O)oc3ccccc3c21)c1ccc(OCC)cc1,amide105252166,Modify the molecule COC(=O)c1ccc(NC(=O)Cn2ncc3c([nH]c4ccccc43)c2=O)cc1 by removing a benzene_ring.,COC(=O)c1ccc(NC(=O)Cn2ncc3c([nH]c4ccccc43)c2=O)cc1,benzene_ring105332235,Please remove a benzene_ring from the molecule CN(C)C(=O)Oc1ccc(C2CCCCC2)cc1.,CN(C)C(=O)Oc1ccc(C2CCCCC2)cc1,benzene_ring105411662,Modify the molecule COc1ccc(O[C@H](C)C(=O)Nc2ccnn2Cc2ccc(C)cc2)cc1 by removing a benzene_ring.,COc1ccc(O[C@H](C)C(=O)Nc2ccnn2Cc2ccc(C)cc2)cc1,benzene_ring1055235827,Modify the molecule CCN(CC)C(=O)Cn1c(CNC(=O)c2ccccc2F)nc2ccccc21 by removing a halo.,CCN(CC)C(=O)Cn1c(CNC(=O)c2ccccc2F)nc2ccccc21,halo105615997,Modify the molecule COC(=O)CNC(=O)c1ccc(OCc2ccccc2C#N)cc1 by removing a amide.,COC(=O)CNC(=O)c1ccc(OCc2ccccc2C#N)cc1,amide1057246361,Please remove a hydroxyl from the molecule Oc1ccc(O)c(C[NH2+]C2CCCCC2)c1.,Oc1ccc(O)c(C[NH2+]C2CCCCC2)c1,hydroxyl1058174155,Modify the molecule COc1ccc(Oc2cc(CNC(=O)Nc3ccccc3)ccn2)cc1 by removing a benzene_ring.,COc1ccc(Oc2cc(CNC(=O)Nc3ccccc3)ccn2)cc1,benzene_ring105967636,Please remove a amine from the molecule O=S(=O)(NCC[C@H]1C[C@@H]2CC[C@H]1C2)N1CCOCC1.,O=S(=O)(NCC[C@H]1C[C@@H]2CC[C@H]1C2)N1CCOCC1,amine106016359,Remove a amide from the molecule O=C(Nc1cc([N+](=O)[O-])ccc1F)[C@@H]1CCCN1C(=O)OCC(F)(F)F.,O=C(Nc1cc([N+](=O)[O-])ccc1F)[C@@H]1CCCN1C(=O)OCC(F)(F)F,amide106168665,Please remove a amide from the molecule Cc1c(C(=O)N[C@@H]2CC[C@@H]([NH+](C)C)C2)cnc2c1c(=O)n(C)c(=O)n2C.,Cc1c(C(=O)N[C@@H]2CC[C@@H]([NH+](C)C)C2)cnc2c1c(=O)n(C)c(=O)n2C,amide106270275,Modify the molecule CC(C)[C@H](C)NC(=O)CSc1nnc(C2CC2)n1C1CC1 by removing a amide.,CC(C)[C@H](C)NC(=O)CSc1nnc(C2CC2)n1C1CC1,amide106325414,Remove a amine from the molecule COc1cc([C@@H]2C3=C(C[C@H](c4ccccc4)CC3=O)Nc3ccc4ncccc4c32)ccc1OC(C)=O.,COc1cc([C@@H]2C3=C(C[C@H](c4ccccc4)CC3=O)Nc3ccc4ncccc4c32)ccc1OC(C)=O,amine106432958,Modify the molecule Cc1nc(CC(=O)N2CCC3(CC2)CC(=O)N(C[C@H]2CCCO2)C3)cs1 by removing a amide.,Cc1nc(CC(=O)N2CCC3(CC2)CC(=O)N(C[C@H]2CCCO2)C3)cs1,amide1065214024,Please remove a benzene_ring from the molecule Cc1cccc(C2=CCN(C(=O)[C@H]3CC(=O)Nc4ccccc43)CC2)c1.,Cc1cccc(C2=CCN(C(=O)[C@H]3CC(=O)Nc4ccccc43)CC2)c1,benzene_ring1066191280,Please remove a benzene_ring from the molecule C=CC1CC[NH+](Cc2ccccc2OCCOC)CC1.,C=CC1CC[NH+](Cc2ccccc2OCCOC)CC1,benzene_ring106736372,Remove a amine from the molecule C[C@H]1[C@@H](C(=O)[O-])CC[NH+]1CC(=O)NNc1ccccn1.,C[C@H]1[C@@H](C(=O)[O-])CC[NH+]1CC(=O)NNc1ccccn1,amine1068150302,Modify the molecule Oc1cccc(CC2(c3ccccc3)C[NH2+]C2)c1 by removing a hydroxyl.,Oc1cccc(CC2(c3ccccc3)C[NH2+]C2)c1,hydroxyl106940919,Please remove a amine from the molecule CCNC(=O)CN(CC)c1ncncc1N.,CCNC(=O)CN(CC)c1ncncc1N,amine1070203128,Please remove a amine from the molecule C[C@@H](C(N)=S)N(C)C(=O)[C@H]1CCO[C@@H]1C.,C[C@@H](C(N)=S)N(C)C(=O)[C@H]1CCO[C@@H]1C,amine1071225077,Modify the molecule Cc1nn(C)c(C)c1C[NH2+]CC(=O)NC1CC1 by removing a amide.,Cc1nn(C)c(C)c1C[NH2+]CC(=O)NC1CC1,amide1072229325,Please remove a halo from the molecule CCCn1cc[nH+]c1Cc1cc(Cl)ncn1.,CCCn1cc[nH+]c1Cc1cc(Cl)ncn1,halo1073149555,Remove a halo from the molecule O=C(Cn1ccc2ccc(F)cc21)N1CCN(CCc2ccccn2)CC1.,O=C(Cn1ccc2ccc(F)cc21)N1CCN(CCc2ccccn2)CC1,halo107448408,Remove a amine from the molecule C[NH+]1CC[C@H](NCc2ccccc2F)[C@H](c2ccccc2)C1.,C[NH+]1CC[C@H](NCc2ccccc2F)[C@H](c2ccccc2)C1,amine107577273,Remove a amide from the molecule CN(C(=O)c1cc(=O)[nH]c2ccc(S(=O)(=O)[N-]c3ccc(F)cc3)cc12)[C@H]1CCS(=O)(=O)C1.,CN(C(=O)c1cc(=O)[nH]c2ccc(S(=O)(=O)[N-]c3ccc(F)cc3)cc12)[C@H]1CCS(=O)(=O)C1,amide1076189406,Remove a halo from the molecule C[C@H](Oc1ccc(Br)cc1)C(=O)N[C@H](C)c1ccc(-n2ccnc2)cc1.,C[C@H](Oc1ccc(Br)cc1)C(=O)N[C@H](C)c1ccc(-n2ccnc2)cc1,halo1077116799,Please remove a benzene_ring from the molecule C[C@H]1CCC[C@@H](OC(=O)c2cccc(C(F)(F)F)c2F)C1.,C[C@H]1CCC[C@@H](OC(=O)c2cccc(C(F)(F)F)c2F)C1,benzene_ring107879534,Modify the molecule COc1ccc(C)cc1[C@@H](C)NC(=O)N1CC[NH+](CC(C)C)CC1 by removing a benzene_ring.,COc1ccc(C)cc1[C@@H](C)NC(=O)N1CC[NH+](CC(C)C)CC1,benzene_ring1079162172,Modify the molecule O=C([C@H]1CC=CCC1)N1CCC([C@@]2(c3cccnc3)NC(=O)N(CCc3cccs3)C2=O)CC1 by removing a amide.,O=C([C@H]1CC=CCC1)N1CCC([C@@]2(c3cccnc3)NC(=O)N(CCc3cccs3)C2=O)CC1,amide1080177055,Modify the molecule Cc1nc(C(=O)N(C)[C@@H](C)C2CC2)nn1-c1c(Cl)cccc1Cl by removing a halo.,Cc1nc(C(=O)N(C)[C@@H](C)C2CC2)nn1-c1c(Cl)cccc1Cl,halo1081225734,Please remove a benzene_ring from the molecule O=C([O-])[C@H](c1c[nH]c2cc(F)ccc12)[NH+]1CCN(c2ccccc2)CC1.,O=C([O-])[C@H](c1c[nH]c2cc(F)ccc12)[NH+]1CCN(c2ccccc2)CC1,benzene_ring1082166513,Remove a amine from the molecule CCCN[C@@H](c1ccc[nH+]c1N)[C@H]1C[NH+]2CCN1CC2.,CCCN[C@@H](c1ccc[nH+]c1N)[C@H]1C[NH+]2CCN1CC2,amine108316221,Please remove a benzene_ring from the molecule O=C(C1CC1)N1CCC[C@H](CNc2ncc3c(n2)CCN3c2ccccc2)C1.,O=C(C1CC1)N1CCC[C@H](CNc2ncc3c(n2)CCN3c2ccccc2)C1,benzene_ring108474762,Please remove a benzene_ring from the molecule C[C@H](c1ccccc1)n1c([C@H]2CC(=O)N(C3CCCC3)C2)nc2ccccc21.,C[C@H](c1ccccc1)n1c([C@H]2CC(=O)N(C3CCCC3)C2)nc2ccccc21,benzene_ring1085182195,Modify the molecule O=[N+]([O-])c1ccccc1-n1nc(Br)nc1Br by removing a halo.,O=[N+]([O-])c1ccccc1-n1nc(Br)nc1Br,halo1086247636,Remove a amide from the molecule CC(C)CC[S@@](=O)[C@@H](C)C(=O)Nc1cc(Cl)ccc1F.,CC(C)CC[S@@](=O)[C@@H](C)C(=O)Nc1cc(Cl)ccc1F,amide1087221522,Please remove a amide from the molecule CCOC(=O)c1c(NC(=O)c2cc(C)no2)sc2c1CC[NH+](C(C)C)C2.,CCOC(=O)c1c(NC(=O)c2cc(C)no2)sc2c1CC[NH+](C(C)C)C2,amide1088164802,Modify the molecule COC(=O)[C@@]1(NC(=O)CCc2ncc(-c3ccccc3)o2)CCOC1 by removing a benzene_ring.,COC(=O)[C@@]1(NC(=O)CCc2ncc(-c3ccccc3)o2)CCOC1,benzene_ring108950392,Please remove a halo from the molecule C[C@@H]1CCCN(C(=O)Nc2cc(Br)c(=O)n(C)c2)[C@H]1CO.,C[C@@H]1CCCN(C(=O)Nc2cc(Br)c(=O)n(C)c2)[C@H]1CO,halo109054617,Remove a amide from the molecule CCCn1/c(=N/C(=O)C[C@H]2CCCCN2C(C)=O)[nH]c2ccccc21.,CCCn1/c(=N/C(=O)C[C@H]2CCCCN2C(C)=O)[nH]c2ccccc21,amide1091114778,Modify the molecule CN(C(=O)c1cc(=O)[nH]c2ccc(Br)cc12)c1ccccc1 by removing a halo.,CN(C(=O)c1cc(=O)[nH]c2ccc(Br)cc12)c1ccccc1,halo1092234885,Remove a amide from the molecule Cc1noc(C)c1C[NH2+][C@@H](C)C(=O)NC1CCCC1.,Cc1noc(C)c1C[NH2+][C@@H](C)C(=O)NC1CCCC1,amide1093205386,Remove a halo from the molecule Cc1cnc(Nc2ccc(NC[C@H]3CCCO3)c(F)c2)c([N+](=O)[O-])c1.,Cc1cnc(Nc2ccc(NC[C@H]3CCCO3)c(F)c2)c([N+](=O)[O-])c1,halo109464535,Modify the molecule Cc1cc(N(C)C[C@@H](O)COc2ccccc2C(F)(F)F)n2ncnc2n1 by removing a halo.,Cc1cc(N(C)C[C@@H](O)COc2ccccc2C(F)(F)F)n2ncnc2n1,halo1095154081,Please remove a amide from the molecule COc1ccc(Cl)cc1N1C(=O)CS[C@@H]1c1ccccc1F.,COc1ccc(Cl)cc1N1C(=O)CS[C@@H]1c1ccccc1F,amide1096205071,Modify the molecule CN(C)c1c(Cl)cccc1NC(=O)c1cc(F)c(F)cc1[N+](=O)[O-] by removing a nitro.,CN(C)c1c(Cl)cccc1NC(=O)c1cc(F)c(F)cc1[N+](=O)[O-],nitro109780869,Modify the molecule CC(=O)NC1CCN(C(=O)N[C@@H](c2ccccn2)C(C)C)CC1 by removing a amide.,CC(=O)NC1CCN(C(=O)N[C@@H](c2ccccn2)C(C)C)CC1,amide1098202846,Modify the molecule CCCC(=O)Nc1cccc(NC(=O)N(CC)C[C@H](C)C#N)c1 by removing a nitrile.,CCCC(=O)Nc1cccc(NC(=O)N(CC)C[C@H](C)C#N)c1,nitrile1099187905,Remove a halo from the molecule CCCC[C@H](CC)C(=O)Nc1ccccc1F.,CCCC[C@H](CC)C(=O)Nc1ccccc1F,halo1100156112,Please remove a halo from the molecule Cc1oc(-c2ccc(Cl)cc2)nc1C[NH+]1CCC[C@@H](C(=O)NC2CC2)C1.,Cc1oc(-c2ccc(Cl)cc2)nc1C[NH+]1CCC[C@@H](C(=O)NC2CC2)C1,halo1101113654,Modify the molecule Cc1cc(C)c(C(=O)Nc2ccc3c(c2)CCCN3C)c(=O)[nH]1 by removing a amide.,Cc1cc(C)c(C(=O)Nc2ccc3c(c2)CCCN3C)c(=O)[nH]1,amide110246721,Remove a amide from the molecule CC(C)CCC(=O)NNC(=O)N1CC[C@H](C)C[C@@H]1C.,CC(C)CCC(=O)NNC(=O)N1CC[C@H](C)C[C@@H]1C,amide1103169815,Remove a benzene_ring from the molecule CC(=O)N(C)c1ccccc1NC(=O)Cc1ccc(NC(=O)C2CC2)cc1.,CC(=O)N(C)c1ccccc1NC(=O)Cc1ccc(NC(=O)C2CC2)cc1,benzene_ring1104122428,Please remove a halo from the molecule CCC[NH+](Cc1nc(Cl)ccc1Cl)C1CCC([NH3+])CC1.,CCC[NH+](Cc1nc(Cl)ccc1Cl)C1CCC([NH3+])CC1,halo1105150300,Please remove a amide from the molecule CSCC(=O)NNC(=O)N[C@@H](C)Cc1c(C)noc1C.,CSCC(=O)NNC(=O)N[C@@H](C)Cc1c(C)noc1C,amide1106212111,Please remove a benzene_ring from the molecule Cc1cc(NC(=O)C(=O)N[C@@H]2CCc3ccccc32)ccc1-n1cnnn1.,Cc1cc(NC(=O)C(=O)N[C@@H]2CCc3ccccc32)ccc1-n1cnnn1,benzene_ring1107115825,Remove a nitrile from the molecule C[C@H](C#N)CNC(=O)C(=O)Nc1ccccc1N1CCCCCC1.,C[C@H](C#N)CNC(=O)C(=O)Nc1ccccc1N1CCCCCC1,nitrile1108132772,Please remove a benzene_ring from the molecule C[C@@H](Sc1nc2sc3c(c2c(=O)n1C)CCC3)C(=O)Nc1ccc(F)c([N+](=O)[O-])c1.,C[C@@H](Sc1nc2sc3c(c2c(=O)n1C)CCC3)C(=O)Nc1ccc(F)c([N+](=O)[O-])c1,benzene_ring1109128600,Modify the molecule Cc1ccn2c(=O)cc(CN(Cc3ccccc3)Cc3ccc(F)cc3)[nH+]c2c1 by removing a benzene_ring.,Cc1ccn2c(=O)cc(CN(Cc3ccccc3)Cc3ccc(F)cc3)[nH+]c2c1,benzene_ring1110227766,Modify the molecule CC[C@@](C)([NH3+])C(=O)NC1CCCCC1 by removing a amide.,CC[C@@](C)([NH3+])C(=O)NC1CCCCC1,amide1111184153,Modify the molecule C[NH+](CC1CCOCC1)C[C@@H]1C[C@@H]1c1ccccc1 by removing a benzene_ring.,C[NH+](CC1CCOCC1)C[C@@H]1C[C@@H]1c1ccccc1,benzene_ring111262140,Modify the molecule O=C(CCn1cncn1)N1CCC[C@H](c2[nH+]ccn2Cc2ccccc2)C1 by removing a benzene_ring.,O=C(CCn1cncn1)N1CCC[C@H](c2[nH+]ccn2Cc2ccccc2)C1,benzene_ring1113161207,Remove a amide from the molecule O=C(Nc1cccc(S(=O)(=O)N2CCCC2)c1)c1cncn1-c1ccccc1.,O=C(Nc1cccc(S(=O)(=O)N2CCCC2)c1)c1cncn1-c1ccccc1,amide111485974,Remove a benzene_ring from the molecule COCc1ccccc1C(=O)NC[C@H](O)c1cccc(C(F)(F)F)c1.,COCc1ccccc1C(=O)NC[C@H](O)c1cccc(C(F)(F)F)c1,benzene_ring111554138,Remove a amide from the molecule Cc1noc(C)c1C[C@@H](C)C(=O)N[C@@H](C#N)C(C)(C)C.,Cc1noc(C)c1C[C@@H](C)C(=O)N[C@@H](C#N)C(C)(C)C,amide1116186079,Remove a benzene_ring from the molecule COc1cc([N+](=O)[O-])ccc1-c1ccc(/C=N\NC(=O)c2ccccc2)o1.,COc1cc([N+](=O)[O-])ccc1-c1ccc(/C=N\NC(=O)c2ccccc2)o1,benzene_ring1117159583,Remove a amine from the molecule CCCS(=O)(=O)[N-]c1ccc(S(=O)(=O)N[C@@H]2CCCC[C@H]2C)cc1F.,CCCS(=O)(=O)[N-]c1ccc(S(=O)(=O)N[C@@H]2CCCC[C@H]2C)cc1F,amine111834663,Remove a amide from the molecule C[C@H]1CCC[C@@H](N(C)C(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)C1.,C[C@H]1CCC[C@@H](N(C)C(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)C1,amide1119132634,Modify the molecule CCNC(=O)Cn1cnc2cc(-c3ccc(OC)cc3)sc2c1=O by removing a amide.,CCNC(=O)Cn1cnc2cc(-c3ccc(OC)cc3)sc2c1=O,amide1120185188,Modify the molecule COc1ccc2c(C)cc(SCC(=O)N[C@@H](C)c3ccccc3)nc2c1 by removing a benzene_ring.,COc1ccc2c(C)cc(SCC(=O)N[C@@H](C)c3ccccc3)nc2c1,benzene_ring112128127,Remove a halo from the molecule O=c1[nH]c(CN(CCC(F)(F)F)C2CCCC2)nc2ccccc12.,O=c1[nH]c(CN(CCC(F)(F)F)C2CCCC2)nc2ccccc12,halo1122223910,Remove a nitrile from the molecule COc1ccc(-c2nc(SCC(C)C)nc([O-])c2C#N)cc1.,COc1ccc(-c2nc(SCC(C)C)nc([O-])c2C#N)cc1,nitrile1123231787,Remove a halo from the molecule COC(=O)c1c(C)sc(-c2c(-c3ccc(Cl)cc3)[nH]c3nc([O-])[nH]c(=O)c23)c1O.,COC(=O)c1c(C)sc(-c2c(-c3ccc(Cl)cc3)[nH]c3nc([O-])[nH]c(=O)c23)c1O,halo1124185721,Remove a amide from the molecule Cc1cc(C)n(CCNC(=O)c2ccc([C@H]3CCC[NH+]3C(C)C)s2)n1.,Cc1cc(C)n(CCNC(=O)c2ccc([C@H]3CCC[NH+]3C(C)C)s2)n1,amide1125193858,Please remove a amide from the molecule CCN(CCNC(=O)[C@H]1CC(=O)N(C2CC2)C1)c1ccccc1C.,CCN(CCNC(=O)[C@H]1CC(=O)N(C2CC2)C1)c1ccccc1C,amide1126171923,Modify the molecule C[C@@H](CCl)CSc1ncnc2c1CCC2 by removing a halo.,C[C@@H](CCl)CSc1ncnc2c1CCC2,halo1127249351,Modify the molecule CC(=O)c1ccc(NCC(C)(C)N2CCOCC2)c([N+](=O)[O-])c1 by removing a nitro.,CC(=O)c1ccc(NCC(C)(C)N2CCOCC2)c([N+](=O)[O-])c1,nitro1128121865,Modify the molecule O=C(Nc1nc2ccc(F)cc2s1)c1ccccc1[N-]S(=O)(=O)c1ccccc1 by removing a benzene_ring.,O=C(Nc1nc2ccc(F)cc2s1)c1ccccc1[N-]S(=O)(=O)c1ccccc1,benzene_ring112992168,Remove a amide from the molecule C[NH+](C)[C@@H](CNC(=O)CCc1ccc(Cl)s1)c1ccc(Cl)cc1.,C[NH+](C)[C@@H](CNC(=O)CCc1ccc(Cl)s1)c1ccc(Cl)cc1,amide1130186229,Remove a benzene_ring from the molecule CNC(=O)c1ccc(OC)c(NC(=O)NCc2cccnc2)c1.,CNC(=O)c1ccc(OC)c(NC(=O)NCc2cccnc2)c1,benzene_ring113182789,Modify the molecule Cc1cc([C@@H](C)[NH2+]Cc2cnn(-c3ccc(F)cc3)c2)c(C)s1 by removing a halo.,Cc1cc([C@@H](C)[NH2+]Cc2cnn(-c3ccc(F)cc3)c2)c(C)s1,halo1132124979,Modify the molecule C[C@H](Nc1ccc2c(c1)OCCCO2)C(=O)Nc1ccccc1[N+](=O)[O-] by removing a nitro.,C[C@H](Nc1ccc2c(c1)OCCCO2)C(=O)Nc1ccccc1[N+](=O)[O-],nitro113393750,Modify the molecule C[C@H]1C[C@@H]1C(=O)N1CCN(C(=O)c2cnc(Oc3ccccc3)cn2)CC1 by removing a amide.,C[C@H]1C[C@@H]1C(=O)N1CCN(C(=O)c2cnc(Oc3ccccc3)cn2)CC1,amide113476912,Remove a amide from the molecule Cc1c(C(=O)N[C@@H](C)CNc2nc3c(c(=O)[nH]2)CCCC3)oc2ccccc12.,Cc1c(C(=O)N[C@@H](C)CNc2nc3c(c(=O)[nH]2)CCCC3)oc2ccccc12,amide113590797,Modify the molecule COc1cc([C@H](C)[NH2+][C@@H]2CCOc3cc(C)c(C)cc32)ccc1F by removing a halo.,COc1cc([C@H](C)[NH2+][C@@H]2CCOc3cc(C)c(C)cc32)ccc1F,halo1136101928,Please remove a amide from the molecule CC[C@@H]1CC(=O)N(C[C@H]([NH2+]C)C2CC2)C1.,CC[C@@H]1CC(=O)N(C[C@H]([NH2+]C)C2CC2)C1,amide1137141314,Please remove a amine from the molecule CCc1nn(C)c(NC[C@@H]2C[C@@H]2c2ccccc2)c1[N+](=O)[O-].,CCc1nn(C)c(NC[C@@H]2C[C@@H]2c2ccccc2)c1[N+](=O)[O-],amine1138232564,Remove a amide from the molecule COc1cc(/C=C/C(=O)N2CCCC[C@H]2C)cc2c1OCCO2.,COc1cc(/C=C/C(=O)N2CCCC[C@H]2C)cc2c1OCCO2,amide1139126053,Modify the molecule CN(CC(C)(C)O)C(=O)c1cccc(OC(F)F)c1 by removing a benzene_ring.,CN(CC(C)(C)O)C(=O)c1cccc(OC(F)F)c1,benzene_ring1140100111,Remove a amide from the molecule C[C@H](NC(=O)Cc1c(Cl)cccc1Cl)c1ccc(S(=O)(=O)N(C)C)cc1.,C[C@H](NC(=O)Cc1c(Cl)cccc1Cl)c1ccc(S(=O)(=O)N(C)C)cc1,amide1141206749,Remove a amide from the molecule COc1ccc([N+](=O)[O-])cc1NC(=O)[C@H](C)SC1=NCCS1.,COc1ccc([N+](=O)[O-])cc1NC(=O)[C@H](C)SC1=NCCS1,amide114224123,Please remove a nitro from the molecule COC(=O)CCCc1nc2ccc([N+](=O)[O-])cc2s1.,COC(=O)CCCc1nc2ccc([N+](=O)[O-])cc2s1,nitro114387140,Remove a benzene_ring from the molecule Cc1nn(CC(C)C)c2sc(C(=O)N[C@H](C)c3ccccc3)cc12.,Cc1nn(CC(C)C)c2sc(C(=O)N[C@H](C)c3ccccc3)cc12,benzene_ring114454236,Remove a amide from the molecule Cc1cc([C@@H]2CCCN(C(=O)c3c[nH]c(C(C)C)n3)C2)n[nH]1.,Cc1cc([C@@H]2CCCN(C(=O)c3c[nH]c(C(C)C)n3)C2)n[nH]1,amide1145211698,Please remove a amide from the molecule CCN(CC(=O)Nc1ccc2c(c1)OCCO2)C(=O)C=C1CCCCC1.,CCN(CC(=O)Nc1ccc2c(c1)OCCO2)C(=O)C=C1CCCCC1,amide1146220103,Remove a amide from the molecule C=CCNC(=O)CN1CCOC[C@H]1C#N.,C=CCNC(=O)CN1CCOC[C@H]1C#N,amide1147175026,Please remove a benzene_ring from the molecule CC1(C)[C@H]2CC[C@]1(C)[C@H](NC(=O)c1ccccc1)C2.,CC1(C)[C@H]2CC[C@]1(C)[C@H](NC(=O)c1ccccc1)C2,benzene_ring1148211524,Remove a benzene_ring from the molecule N#Cc1ccc(C(=O)Nc2nnc(-c3ccc(Br)s3)o2)cc1.,N#Cc1ccc(C(=O)Nc2nnc(-c3ccc(Br)s3)o2)cc1,benzene_ring114941787,Remove a benzene_ring from the molecule COc1cc(OC)cc([C@H]2CCN(C(=O)[C@@H]3CCO[C@H]3C)C2)c1.,COc1cc(OC)cc([C@H]2CCN(C(=O)[C@@H]3CCO[C@H]3C)C2)c1,benzene_ring115039545,Please remove a benzene_ring from the molecule COc1ccc(-c2csc(NC(=O)NC[C@@H]3CCCO3)n2)cc1.,COc1ccc(-c2csc(NC(=O)NC[C@@H]3CCCO3)n2)cc1,benzene_ring1151246440,Modify the molecule CC[C@@H](C)CN(C)C(=O)Nc1ccc(F)c(C(=O)N(C)C)c1 by removing a benzene_ring.,CC[C@@H](C)CN(C)C(=O)Nc1ccc(F)c(C(=O)N(C)C)c1,benzene_ring1152230340,Remove a halo from the molecule CCCNC(=O)NCc1cc[nH+]c(N2CCN(c3ccc(F)cc3)CC2)c1.,CCCNC(=O)NCc1cc[nH+]c(N2CCN(c3ccc(F)cc3)CC2)c1,halo115360481,Please remove a amide from the molecule O=C1[C@@H](Sc2nc3ccccc3o2)CCN1c1c(F)cccc1F.,O=C1[C@@H](Sc2nc3ccccc3o2)CCN1c1c(F)cccc1F,amide115424593,Please remove a amide from the molecule N#Cc1ccc(C(=O)N2CCCS/C2=N\c2cccc(C(F)(F)F)c2)cc1.,N#Cc1ccc(C(=O)N2CCCS/C2=N\c2cccc(C(F)(F)F)c2)cc1,amide1155194918,Modify the molecule CCOc1ccc2nc(N3CCC[C@@H]3C(=O)N(C)CCc3ccccn3)nc(C)c2c1 by removing a amide.,CCOc1ccc2nc(N3CCC[C@@H]3C(=O)N(C)CCc3ccccn3)nc(C)c2c1,amide1156131315,Modify the molecule CC(=O)C1=C(C)[C@@H](C(=O)N2CCN(c3cccc(C)c3C)CC2)N=C1C by removing a amide.,CC(=O)C1=C(C)[C@@H](C(=O)N2CCN(c3cccc(C)c3C)CC2)N=C1C,amide115745775,Modify the molecule Cc1nc(CC(CO)(CO)Cc2ccccc2)sc1C by removing a benzene_ring.,Cc1nc(CC(CO)(CO)Cc2ccccc2)sc1C,benzene_ring1158107239,Modify the molecule O=C(CSc1ncnc2ccsc12)c1cc(F)ccc1F by removing a halo.,O=C(CSc1ncnc2ccsc12)c1cc(F)ccc1F,halo1159196414,Please remove a hydroxyl from the molecule CCC[NH2+][C@@]1(CO)CC[C@@H](n2c(C)nc3ccccc32)C1.,CCC[NH2+][C@@]1(CO)CC[C@@H](n2c(C)nc3ccccc32)C1,hydroxyl1160227318,Remove a halo from the molecule Cc1c(Cl)cccc1S(=O)(=O)NC[C@H](c1cccs1)N(C)C.,Cc1c(Cl)cccc1S(=O)(=O)NC[C@H](c1cccs1)N(C)C,halo1161213397,Remove a amide from the molecule Cc1csc(NC(=O)c2cnc([C@@H]3CCC[NH+](C)C3)cn2)n1.,Cc1csc(NC(=O)c2cnc([C@@H]3CCC[NH+](C)C3)cn2)n1,amide1162165929,Remove a amine from the molecule CCc1cccc(N[C@@H]2c3ncccc3C(=O)N2c2cc(OC)ccc2OC)c1.,CCc1cccc(N[C@@H]2c3ncccc3C(=O)N2c2cc(OC)ccc2OC)c1,amine116358351,Please remove a amine from the molecule CCN[C@H](c1cc(C)cnc1N)C(C)(C)[NH+](C)C.,CCN[C@H](c1cc(C)cnc1N)C(C)(C)[NH+](C)C,amine1164114805,Please remove a hydroxyl from the molecule C[C@H](NC(=O)N[C@H](C)[C@@H](C)CO)c1cccc(N2CCCC2)c1.,C[C@H](NC(=O)N[C@H](C)[C@@H](C)CO)c1cccc(N2CCCC2)c1,hydroxyl1165189974,Modify the molecule CC[C@H](C)NC(=O)[C@H]1CC[C@H](c2ccccc2)N(C(C)=O)C1 by removing a benzene_ring.,CC[C@H](C)NC(=O)[C@H]1CC[C@H](c2ccccc2)N(C(C)=O)C1,benzene_ring116623455,Please remove a amide from the molecule C[C@@H](NC(=O)[C@H]1CC=CCC1)c1ccc(F)c(F)c1.,C[C@@H](NC(=O)[C@H]1CC=CCC1)c1ccc(F)c(F)c1,amide116740257,Please remove a halo from the molecule O=C(NCCc1nc2ccccc2s1)c1ccc(OCC(F)F)nc1.,O=C(NCCc1nc2ccccc2s1)c1ccc(OCC(F)F)nc1,halo1168104408,Modify the molecule C[C@H]1c2ccccc2O[C@@H]1C(=O)OCc1cc(Cl)c2c(c1)OCO2 by removing a halo.,C[C@H]1c2ccccc2O[C@@H]1C(=O)OCc1cc(Cl)c2c(c1)OCO2,halo116920512,Remove a halo from the molecule Cc1ccc(NC(=O)C[n+]2ccc(Cc3ccccc3)cc2)cc1Cl.,Cc1ccc(NC(=O)C[n+]2ccc(Cc3ccccc3)cc2)cc1Cl,halo1170224288,Modify the molecule CS[C@@H](C#N)C(F)(F)F by removing a halo.,CS[C@@H](C#N)C(F)(F)F,halo117166403,Modify the molecule CC(C)c1nnsc1CNC(=O)c1nc2ccccn2c1F by removing a halo.,CC(C)c1nnsc1CNC(=O)c1nc2ccccn2c1F,halo1172156575,Please remove a benzene_ring from the molecule COc1ccccc1OCC[NH2+]C[C@@]1(C)CC(C)=NO1.,COc1ccccc1OCC[NH2+]C[C@@]1(C)CC(C)=NO1,benzene_ring1173225543,Modify the molecule COc1cc(NC(=O)C[NH+]2CCCN(c3ncccn3)CC2)ccc1Cl by removing a halo.,COc1cc(NC(=O)C[NH+]2CCCN(c3ncccn3)CC2)ccc1Cl,halo1174106946,Please remove a halo from the molecule CCOC(=O)C(F)(F)Oc1cc(C)ccc1C.,CCOC(=O)C(F)(F)Oc1cc(C)ccc1C,halo1175205953,Modify the molecule Cc1cc(C)cc(CCNC(=O)N(C)[C@H](C)c2ccco2)c1 by removing a benzene_ring.,Cc1cc(C)cc(CCNC(=O)N(C)[C@H](C)c2ccco2)c1,benzene_ring1176104685,Remove a amine from the molecule Cn1cc[nH+]c1[C@@H](NCC(C)(C)S(C)(=O)=O)c1cccs1.,Cn1cc[nH+]c1[C@@H](NCC(C)(C)S(C)(=O)=O)c1cccs1,amine1177225419,Remove a amine from the molecule Nc1ccc(COCc2ccccc2)c2ncccc12.,Nc1ccc(COCc2ccccc2)c2ncccc12,amine1178194300,Remove a amine from the molecule Cn1cnnc1CCn1nnnc1N.,Cn1cnnc1CCn1nnnc1N,amine1179180209,Please remove a amide from the molecule Cc1ccc(NC(=O)c2[nH]nc([N+](=O)[O-])c2Br)c(C)c1.,Cc1ccc(NC(=O)c2[nH]nc([N+](=O)[O-])c2Br)c(C)c1,amide1180191905,Modify the molecule C[NH2+]C[C@H](C)C(=O)N1CC[C@H](C)[C@H]2CCCC[C@@H]21 by removing a amide.,C[NH2+]C[C@H](C)C(=O)N1CC[C@H](C)[C@H]2CCCC[C@@H]21,amide1181233001,Please remove a benzene_ring from the molecule COc1ccc(CN2CC[NH+](C)[C@@]3(CCNC(=O)CC3)C2)cc1Cn1cccn1.,COc1ccc(CN2CC[NH+](C)[C@@]3(CCNC(=O)CC3)C2)cc1Cn1cccn1,benzene_ring118223943,Modify the molecule CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc2ccc(Cl)cc2n1 by removing a halo.,CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc2ccc(Cl)cc2n1,halo1183236121,Please remove a benzene_ring from the molecule CCOc1ccc(-n2c(-c3ccccc3)c(CC)n3c4c(=O)n(C)c(=O)n(C)c4nc23)cc1.,CCOc1ccc(-n2c(-c3ccccc3)c(CC)n3c4c(=O)n(C)c(=O)n(C)c4nc23)cc1,benzene_ring118420725,Remove a nitrile from the molecule C[C@@H](c1ccccc1)[NH+](C)CCOc1ccc(C#N)cc1.,C[C@@H](c1ccccc1)[NH+](C)CCOc1ccc(C#N)cc1,nitrile1185166022,Please remove a benzene_ring from the molecule Cc1ccc(Br)cc1S(=O)(=O)N1CCC[C@H](N2CCCC2=O)C1.,Cc1ccc(Br)cc1S(=O)(=O)N1CCC[C@H](N2CCCC2=O)C1,benzene_ring1186200076,Modify the molecule O=C(Nc1ccc(N2CCOCC2)cc1C(F)(F)F)NC1CCCCCC1 by removing a benzene_ring.,O=C(Nc1ccc(N2CCOCC2)cc1C(F)(F)F)NC1CCCCCC1,benzene_ring1187113041,Please remove a amine from the molecule C[C@H]1C[C@@H]([NH3+])CN(Cc2nc(N)nc(N(C)C)n2)C1.,C[C@H]1C[C@@H]([NH3+])CN(Cc2nc(N)nc(N(C)C)n2)C1,amine1188231004,Modify the molecule Cc1nc(N2CCC[C@@H]2C(=O)NCCC2=CC[C@@H]3C[C@H]2C3(C)C)nc2cc(S(C)(=O)=O)ccc12 by removing a amide.,Cc1nc(N2CCC[C@@H]2C(=O)NCCC2=CC[C@@H]3C[C@H]2C3(C)C)nc2cc(S(C)(=O)=O)ccc12,amide118979413,Please remove a amide from the molecule CNC(=O)[C@@H](C)n1c2ccccc2c2cn[nH]c(=O)c21.,CNC(=O)[C@@H](C)n1c2ccccc2c2cn[nH]c(=O)c21,amide119050476,Modify the molecule C[C@@H]1C[NH+](Cc2c[nH]nc2-c2ccc(F)cc2)CC[C@@]1(O)C1CCOCC1 by removing a hydroxyl.,C[C@@H]1C[NH+](Cc2c[nH]nc2-c2ccc(F)cc2)CC[C@@]1(O)C1CCOCC1,hydroxyl119157261,Modify the molecule CCOC[C@H]1CCN(C(=O)N[C@@H](C)c2ccc(-n3cncn3)cc2)C1 by removing a benzene_ring.,CCOC[C@H]1CCN(C(=O)N[C@@H](C)c2ccc(-n3cncn3)cc2)C1,benzene_ring119260135,Modify the molecule CCn1nc(C)c(C[NH2+]Cc2cn(-c3ccc(F)cc3F)nc2-c2ccccc2C)c1C by removing a benzene_ring.,CCn1nc(C)c(C[NH2+]Cc2cn(-c3ccc(F)cc3F)nc2-c2ccccc2C)c1C,benzene_ring1193202632,Remove a amide from the molecule C#Cc1cccc(NC(=O)C(=O)NC2CCN(C(=O)c3ccco3)CC2)c1.,C#Cc1cccc(NC(=O)C(=O)NC2CCN(C(=O)c3ccco3)CC2)c1,amide119499742,Please remove a amide from the molecule COc1cc2c(cc1OC)CCN(C(=O)c1cnn(C)c1C)CC2.,COc1cc2c(cc1OC)CCN(C(=O)c1cnn(C)c1C)CC2,amide1195154577,Modify the molecule C=C(C)CN(CC)C(=O)CN1CCN(C(=O)C[NH+](C)C)CC1 by removing a amide.,C=C(C)CN(CC)C(=O)CN1CCN(C(=O)C[NH+](C)C)CC1,amide1196223290,Please remove a amide from the molecule Cc1ccc(N2CCOC2=O)cc1NC(=O)[C@H](C)Sc1ccccc1.,Cc1ccc(N2CCOC2=O)cc1NC(=O)[C@H](C)Sc1ccccc1,amide119771599,Remove a amine from the molecule C[C@@H]1CN(C(=O)c2cn[nH]c2N)C[C@H]1C.,C[C@@H]1CN(C(=O)c2cn[nH]c2N)C[C@H]1C,amine119854086,Remove a nitrile from the molecule CCOC(=O)C[C@H](C)Nc1snc(Cl)c1C#N.,CCOC(=O)C[C@H](C)Nc1snc(Cl)c1C#N,nitrile119923755,Remove a amide from the molecule CCc1ccc(-c2nc(CC(=O)Nc3nc(C)c(C)s3)cs2)cc1.,CCc1ccc(-c2nc(CC(=O)Nc3nc(C)c(C)s3)cs2)cc1,amide1200201362,Remove a amide from the molecule N#Cc1cn(C2CC2)c(=O)n(CC(=O)N2CCN(C(=O)c3ccco3)CC2)c1=O.,N#Cc1cn(C2CC2)c(=O)n(CC(=O)N2CCN(C(=O)c3ccco3)CC2)c1=O,amide
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