mhjiang0408/MAC_Bench

1journal,id,question,cover_image,answer,option_A,option_A_path,option_A_embedding_name,option_A_embedding_id,option_B,option_B_path,option_B_embedding_name,option_B_embedding_id,option_C,option_C_path,option_C_embedding_name,option_C_embedding_id,option_D,option_D_path,option_D_embedding_name,option_D_embedding_id,split2Current Biology,34_10,Which of the following options best describe the cover story?,"On the cover: White shark (Carcharodon carcharias) swimming in the clear waters around Guadalupe Island (Mexico). In this issue, Wagner et al. use genome-wide sequencing to show global white shark populations are divided into3three distinct genetic lineages: Atlantic/Mediterranean, North Pacific, and Indo-Pacific.4These lineages diverged 100,000–200,000 years ago and rarely interbreed. Image credit:5Getty/Cultura Exclusive/Rodrigo Friscione.",A,MAC_Bench/Cell/Cover/Current Biology/34_10.png,MAC_Bench/Cell/Cover/Current Biology/34_10.png,groundtruth,34_10.txt,MAC_Bench/Cell/Cover/Current Biology/32_1.png,MAC_Bench/Cell/Cover/Current Biology/32_1.png,ave_3,32_1.txt,MAC_Bench/Cell/Cover/Current Biology/19_13.png,MAC_Bench/Cell/Cover/Current Biology/19_13.png,vitg,19_13.txt,MAC_Bench/Cell/Cover/Current Biology/26_10.png,MAC_Bench/Cell/Cover/Current Biology/26_10.png,clip,26_10.txt,train6Nature Food,5_2,Which of the following options best describe the cover story?,"Cultivated meat techno-economic analyses7Cultivated meat could provide dietary protein with lower resource use than conventional beef production. Current techno-economic analyses exploring scaled-up production adopt different assumptions and processing approaches. Scale-up feasibility is likely to depend on the use of plant-based components to save costs on cell culture media, developing sustainable food-grade aseptic conditions and extensive scaling of related supply chains. Technological advancements need to address serum-free differentiation, new bioreactor designs, media recycling and valorization, and facility design that can support large-scale production.8See Shirwaiker et al.9Image: Jochen Tack / Alamy Stock Photo. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Food/2_1.png,MAC_Bench/Nature/Cover/Nature Food/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Food/3_3.png,MAC_Bench/Nature/Cover/Nature Food/3_3.png,vith,3_3.txt,MAC_Bench/Nature/Cover/Nature Food/3_10.png,MAC_Bench/Nature/Cover/Nature Food/3_10.png,ave_3,3_10.txt,MAC_Bench/Nature/Cover/Nature Food/5_2.png,MAC_Bench/Nature/Cover/Nature Food/5_2.png,groundtruth,5_2.txt,train10Trends in Genetics,40_2,Which of the following options best describe the cover story?,"The numerous alleles of the complementary sex determiner (csd) gene form11the basis of sex determination in the honeybee (Apis mellifera). In this issue, Jana Seiler12and Martin Beye review how different and identical csd alleles form a sex determination13signal and how this realizes sexual differentiation in downstream pathways. They also14discuss how mutation and selection have shaped the evolution and function of the15complementary sex determination system. Photograph by Christian Verhoeven.",C,MAC_Bench/Cell/Cover/Trends in Genetics/29_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/29_2.png,clip,29_2.txt,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,MAC_Bench/Cell/Cover/Trends in Genetics/35_9.png,ave_2,35_9.txt,MAC_Bench/Cell/Cover/Trends in Genetics/40_2.png,MAC_Bench/Cell/Cover/Trends in Genetics/40_2.png,groundtruth,40_2.txt,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,MAC_Bench/Cell/Cover/Trends in Genetics/39_6.png,ave_3,39_6.txt,val16Trendsin Neurosciences,47_9,Which of the following options best describe the cover story?,"Research in brain aging has historically focused on advanced age, when17the effects of time on cognitive health and physical functioning are most manifest.18However, an increasing number of studies are finding that changes during middle19age are prognostic of future cognitive health. In this issue of Trends in Neurosciences,20Dohm-Hansen and colleagues review emerging evidence indicating that middle age is21a period defined by unique processes both within and outside the brain that influence22cognitive aging trajectories. Many of these processes, ranging from genetic expression23to memory for everyday events, display non-linear relationships with chronological24age.25This opens for the possibility of identifying aging processes that are especially26relevant27during middle age and could have bearing on health trajectories in later life. Photo28credits: Ivcandy/Getty Images and Macauley Smith Breault/SciDraw.",B,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_8.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/37_8.png,vith,37_8.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_9.png,groundtruth,47_9.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/39_6.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/39_6.png,vitg,39_6.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_7.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_7.png,clip,47_7.txt,train29Nature Protocols,19_12,Which of the following options best describe the cover story?,"Label-free X-ray microscopy of nanomedicines and organelles in intact single cells at nanometer resolution using synchrotron radiation30A composite image of a single cell visualized in 3D and a synchrotron radiation facility. The method uses X-rays generated via synchrotron radiation and enables the subcellular localization of nanomedicines in single cells, at nanometer resolution, as a robust approach to characterize interactions between nanomaterials and cells. See Cao et al.31Image: Mingjing Cao, Yaling Wang and Chunying Chen, National Center for Nanoscience and Technology of China. Cover design: S. Whitham.",D,MAC_Bench/Nature/Cover/Nature Protocols/14_1.png,MAC_Bench/Nature/Cover/Nature Protocols/14_1.png,vitg,14_1.txt,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,MAC_Bench/Nature/Cover/Nature Protocols/16_11.png,clip,16_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/15_11.png,MAC_Bench/Nature/Cover/Nature Protocols/15_11.png,vith,15_11.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_12.png,MAC_Bench/Nature/Cover/Nature Protocols/19_12.png,groundtruth,19_12.txt,train32ACS Bio & Med Chem Au,2024_3,Which of the following options best describe the cover story?,Hwang et al. develop a new sustainable bioproduction platform to generate disulfide-constrained peptide (DCP) and its functionalized analogues. DCPs are targeted to the periplasm in E.,B,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_3.png,ave_2,2022_3.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_5.png,MAC_Bench/ACS/Cover/ACS Bio & Med Chem Au/2022_5.png,clip,2022_5.txt,train33Biophysical Reports,4_2,Which of the following options best describe the cover story?,"On the cover: The cover shows an illustration of a new, multipurpose, graphical user34interface-based open-source toolbox offering unbiased analysis of single-molecule35spectroscopic data. DOI: https://doi.org/10.1016/j.bpr.2024.100173.",D,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/2_3.png,MAC_Bench/Cell/Cover/Biophysical Reports/2_3.png,ave_1,2_3.txt,MAC_Bench/Cell/Cover/Biophysical Reports/3_4.png,MAC_Bench/Cell/Cover/Biophysical Reports/3_4.png,ave_2,3_4.txt,MAC_Bench/Cell/Cover/Biophysical Reports/4_2.png,MAC_Bench/Cell/Cover/Biophysical Reports/4_2.png,groundtruth,4_2.txt,test36Cell Reports Physical Science,5_4,Which of the following options best describe the cover story?,"On the cover: The cover of this month’s issue of Cell Reports Physical Science summarizes the research of Li et al. on the preparation of multiscale hydrogels. The background represents a hydrogel’s37macroporous structure, which provides space for cells. The hydrogel (upper left) affects38mesenchymal stem-cell fate with local stiffness-enhancing structures (lower left)39and promotes bone regeneration (bottom right). This research has promising applications,40such as the possibility to be used as a 3D printing ink (upper right). The cover was41produced by Zhibao Xiao.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,vitg,5_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_10.png,vith,3_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_4.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_4.png,clip,4_4.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_4.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_4.png,groundtruth,5_4.txt,train42Nature Reviews Materials,9_3,Which of the following options best describe the cover story?,"Universal access to fresh water and modern energy are key to a sustainable and just future. Sorbent materials that capture and release water molecules are at the heart of technologies that turn the Earth’s abundant atmospheric moisture into drinkable water and energy, making these essential resources more accessible to all. See the Editorial43Cover image: Jiaxing Xu, Tingxian Li and Hangzhou Sphere Studio. Cover design: David Johnston.",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,vith,9_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,vitg,7_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_8.png,clip,5_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_3.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_3.png,groundtruth,9_3.txt,val44Nature Water,2_12,Which of the following options best describe the cover story?,"Drinking water in small and remote communities45While most people in high-income countries have access to safely managed drinking water, there are still gaps in service provision that prevent countries from meeting the SDG 6.1 target of “achieving universal and equitable access to safe and affordable drinking water for all by 2030”. In Australia, for example, drinking water quality breaches have been documented in small, rural and remote (SRR) communities. Ana Manero and colleagues have now estimated the Australian residents’ willingness to pay for improved drinking water services in these SRR communities.46The cover shows the painting The Unity of Water by Walmajarri, Gooniyandi, Bunuba and Nyikina man — Hozaus Claire. In the artist’s own words: “Every water is connected in many ways. Water has its own cycle to resource the natural environment. Every water has a story, every story has a meaning. All surface water has different tribes that tells a story about the water and connection to the First Law of the Land. And the access to the water provides leadership to the tribes that lives near the water that keeps the story strong. The ground water has a significant and secret story that keeps the spirit of the water and the land alive. That is why every river is connected. The connection is under the ground on the land and in the air. How the animals use the water is how people should treat the water and listen to our Elders story songs and dance. The spirit of water is only listened to and seen. In the songs stories and dance of the First Nation of the Land. In this painting, I show connections of ground water and surface water. It also shows that water holes, creeks, springs, rivers and ocean are connected.”47See Manero et al.48IMAGE: The cover shows the painting The Unity of Water by Walmajarri, Gooniyandi, Bunuba and Nyikina man — Hozaus Claire. COVER DESIGN: Valentina Monaco.",A,MAC_Bench/Nature/Cover/Nature Water/2_12.png,MAC_Bench/Nature/Cover/Nature Water/2_12.png,groundtruth,2_12.txt,MAC_Bench/Nature/Cover/Nature Water/2_2.png,MAC_Bench/Nature/Cover/Nature Water/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Water/2_4.png,MAC_Bench/Nature/Cover/Nature Water/2_4.png,clip,2_4.txt,MAC_Bench/Nature/Cover/Nature Water/1_11.png,MAC_Bench/Nature/Cover/Nature Water/1_11.png,ave_3,1_11.txt,train49Neuron,113_4,Which of the following options best describe the cover story?,"On the cover: In this special issue of Neuron, we present a collection of reviews and perspectives on the neurobiology of aging.50The causes of brain aging are multidimensional and complex. Highlighting this, the51cover image is provided by Schwartz and colleagues, who discuss the impact of the immune system on brain aging and propose the provocative52idea of anti-aging immune therapy.",B,MAC_Bench/Cell/Cover/Neuron/73_3.png,MAC_Bench/Cell/Cover/Neuron/73_3.png,ave_2,73_3.txt,MAC_Bench/Cell/Cover/Neuron/113_4.png,MAC_Bench/Cell/Cover/Neuron/113_4.png,groundtruth,113_4.txt,MAC_Bench/Cell/Cover/Neuron/113_1.png,MAC_Bench/Cell/Cover/Neuron/113_1.png,clip,113_1.txt,MAC_Bench/Cell/Cover/Neuron/75_4.png,MAC_Bench/Cell/Cover/Neuron/75_4.png,ave_3,75_4.txt,val53Journal of Chemical Information and Modeling,2025_1,Which of the following options best describe the cover story?,"This figure shows materials being ""scanned"" by AI, as our method applies an AI-based filter to assess prediction reliability of AI-based regression models. The depicted structures are from the COD database (CC0 license) and were processed using the Avogadro software.",C,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2016_11.png,ave_1,2016_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2010_6.png,clip,2010_6.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_6.png,MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2015_6.png,ave_2,2015_6.txt,train54Nature Reviews Physics,6_6,Which of the following options best describe the cover story?,"The cover of this issue is based on a network of ferroelectric domain walls in ErMnO3. See Everschor-Sitte et al.55Image: Dennis Meier, Jakob Schaab, amb design & illustrations. Cover design: Susanne Harris. [Note: The image credit originally published was incorrect; it has now been updated.]",D,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_4.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_4.png,vitg,5_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_6.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/3_6.png,vith,3_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_6.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_6.png,groundtruth,6_6.txt,train56Journal of Chemical Theory and Computation,2024_14,Which of the following options best describe the cover story?,"This work presents a novel automatic machine learning-based manifold learning approach to discover essential transition components with kinetic properties. The circuit in the cover story represents neurons transmitting kinetic information from high-dimensional space into the protein structure of interest. The conformational space of the peptide (shown as sticks) is explored comprehensively in the protein pocket with shape complementarity considered. The lower curves with starring points indicate the long-lasting conformations, which can be used to guide subsequent drug design and lead optimization.",C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2023_17.png,vith,2023_17.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2019_2.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2019_2.png,vitg,2019_2.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_14.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_10.png,clip,2022_10.txt,train57Nature Reviews Clinical Oncology,21_9,Which of the following options best describe the cover story?,"Dendritic cells as orchestrators of immune responses, inspired by the Review on p257.58Cover design: Lara Crow",B,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_2.png,clip,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_9.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/21_9.png,groundtruth,21_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_11.png,vith,20_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Clinical Oncology/20_4.png,vitg,20_4.txt,test59CHEMICAL REVIEWS,2025_1,Which of the following options best describe the cover story?,"Illustration of an electrochemical random access memory (ECRAM) that functions by moving mobile defects, such as protons, lithium ions, or oxygen vacancies, between the top (reservoir) and bottom (channel) electrodes made of various functional materials and connected by a solid electrolyte (middle, light blue). The mobile defects tune the electronic conductance through reversible redox reactions. Although ECRAM shares many fundamental aspects with rechargeable batteries, computing applications require many millions of devices, scaled down to sub-micrometer dimensions, while achieving reliable electronic-state tuning at scaled-up rates and endurances and with minimal energy dissipation.",C,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2016_4.png,clip,2016_4.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2022_21.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2022_21.png,vith,2022_21.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_1.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2023_17.png,MAC_Bench/ACS/Cover/CHEMICAL REVIEWS/2023_17.png,ave_1,2023_17.txt,test60Nature Reviews Psychology,3_12,Which of the following options best describe the cover story?,"This month we launch a new collection of pieces that highlight ways to improve doctoral education and support graduate student trainees to their fullest potential.61Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_2.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/2_2.png,ave_2,2_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/4_1.png,clip,4_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_3.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_3.png,vitg,3_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_12.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_12.png,groundtruth,3_12.txt,train62Nature Mental Health,3_1,Which of the following options best describe the cover story?,"Machine learning in mental health research63The capabilities of machine learning, and artificial intelligence more broadly, have captured our collective imagination. A discipline that once seemed more like science fiction, machine learning is now being harnessed and applied to many fields, including psychiatry and mental health research. Machine learning holds the ability to combine massive datasets — brain scan images, electronic health records and real-time affective measurements — to identify relationships and patterns among variables that may be used to stratify risk, diagnose disorders or predict treatment response. The January cover is intended to evoke the notion that applying machine learning techniques in mental health research is both an art and a science. Just as machine learning models must be refined by human-defined parameters, researchers are also learning how best to apply these techniques in a symbiotic relationship between humans and technology.64Read more in our Editorial, and see Lucasius et al.on using machine learning in psychiatry.65Image: Marina Spence and Jackie Niam / iStock / Getty Images Plus. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Mental Health/1_4.png,MAC_Bench/Nature/Cover/Nature Mental Health/1_4.png,ave_2,1_4.txt,MAC_Bench/Nature/Cover/Nature Mental Health/3_1.png,MAC_Bench/Nature/Cover/Nature Mental Health/3_1.png,groundtruth,3_1.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,ave_3,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,clip,2_6.txt,val66Structure,33_2,Which of the following options best describe the cover story?,"On the cover: Alternative complex III from Chloroflexus aurantiacus (CaACIII) is a multi-subunit quinol acceptor oxidoreductase that couples quinol oxidation67with transmembrane proton translocation in respiratory and photosynthetic electron68transport chains. This image shows CaACIII structures determined by X-ray crystallography69and cryoelectron microscopy. The CaACIII crystal structure presented in this issue70by Wu et al. highlights the conformational stability of its core functional modules and reveals71local flexibility in regions with low sequence conservation.",B,MAC_Bench/Cell/Cover/Structure/29_6.png,MAC_Bench/Cell/Cover/Structure/29_6.png,clip,29_6.txt,MAC_Bench/Cell/Cover/Structure/33_2.png,MAC_Bench/Cell/Cover/Structure/33_2.png,groundtruth,33_2.txt,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,vith,22_7.txt,MAC_Bench/Cell/Cover/Structure/32_5.png,MAC_Bench/Cell/Cover/Structure/32_5.png,vitg,32_5.txt,test72ACS Chemical Neuroscience,2024_19,Which of the following options best describe the cover story?,"This image shows a large subpopulation of 5-HT neurons (TPH2 immunolabeling in red) expressing the vesicular glutamate transporter 3 (VGLUT3 immunolabeling in green), thus having the capacity to co-release both 5-HT and glutamate. Gullino et al. show that these neurons are involved in",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_19.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_19.png,groundtruth,2024_19.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_22.png,clip,2021_22.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,ave_2,2022_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,vith,2017_3.txt,train73Nature Electronics,7_4,Which of the following options best describe the cover story?,"An optical neural interface in miniature74A miniaturized implantable optical device, which is thin enough to lie within the subdural space of a primate brain, can be created using an integrated circuit that provides both fluorescence imaging and optogenetic stimulation. The optical microscopy image on the cover shows a section of the integrated circuit, which is fabricated using complementary metal–oxide–semiconductor (CMOS) technology, and highlights the photodiode pixels used for imaging in the neural interface.75See Pollmann et al.76Image: Eric Pollmann, Columbia University. Cover design: Lauren Heslop.",A,MAC_Bench/Nature/Cover/Nature Electronics/7_4.png,MAC_Bench/Nature/Cover/Nature Electronics/7_4.png,groundtruth,7_4.txt,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_4.png,MAC_Bench/Nature/Cover/Nature Electronics/6_4.png,clip,6_4.txt,MAC_Bench/Nature/Cover/Nature Electronics/5_7.png,MAC_Bench/Nature/Cover/Nature Electronics/5_7.png,vith,5_7.txt,train77Developmental Cell,59_3,Which of the following options best describe the cover story?,"On the cover: This image depicts mRNA translation within the appressorium of the rice78blast fungus Magnaporthe oryzae. Ribosomes (purple) move along the mRNA, decoding genetic information. The eukaryotic79elongation factor (eEF1, yellow) escorts aminoacyl-tRNA (blue) to the ribosome, facilitating80protein synthesis. A conserved tRNA modification (red dot) enhances eEF1-tRNA interaction,81promoting the translation of genes essential for appressorium function and fungal82infection. In the upper right, an asexual spore develops into a dome-shaped appressorium83(gray) following this mRNA translation. To learn more about how this modification84controls fungal infection, see He et al. Image credit: Rongrong He, Yinan Li, and Zhipeng Zhou.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_3.png,MAC_Bench/Cell/Cover/Developmental Cell/59_3.png,groundtruth,59_3.txt,MAC_Bench/Cell/Cover/Developmental Cell/17_5.png,MAC_Bench/Cell/Cover/Developmental Cell/17_5.png,clip,17_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/18_5.png,MAC_Bench/Cell/Cover/Developmental Cell/18_5.png,vith,18_5.txt,MAC_Bench/Cell/Cover/Developmental Cell/53_6.png,MAC_Bench/Cell/Cover/Developmental Cell/53_6.png,vitg,53_6.txt,test85Environment & Health,2024_2,Which of the following options best describe the cover story?,"Prenatal exposure to F-53B exerts detrimental effects on synaptic development in fetal mice. F-53B could bind with the protein of PKA and CREB1 in hippocampal neurons of mice which prevents PKA translocation from cytoplasm to nucleus, and further inhibits the phosphorylation of nuclear CREB.",B,MAC_Bench/ACS/Cover/Environment & Health/2024_11.png,MAC_Bench/ACS/Cover/Environment & Health/2024_11.png,ave_2,2024_11.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,MAC_Bench/ACS/Cover/Environment & Health/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,MAC_Bench/ACS/Cover/Environment & Health/2023_1.png,ave_3,2023_1.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,clip,2024_7.txt,val86Nature Chemistry,16_12,Which of the following options best describe the cover story?,"Identifying an elusive intermediate87Trans–cis photoisomerization plays an essential role in various biological settings such as vision, ion pumping, and light sensing. The prototypical trans–cis photoisomerization of stilbenes (an artistic impression of which is depicted on the cover) is thought to occur via an intermediate with a perpendicular conformation; however, its unambiguous identification has thus far proved difficult. Using ultrafast Raman spectroscopy and ab initio molecular dynamics simulations, Tahei Tahara and colleagues now characterize the common, perpendicular intermediate of stilbene photoisomerization, revealing its ultrafast birth and decay upon photoexcitation of the trans and cis forms.88See Kuramochi et al.89Image: Takaya Fukui, Art Action Inc.. Cover design: Tulsi Voralia",C,MAC_Bench/Nature/Cover/Nature Chemistry/13_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_6.png,vitg,13_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/14_6.png,MAC_Bench/Nature/Cover/Nature Chemistry/14_6.png,vith,14_6.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_12.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_12.png,groundtruth,16_12.txt,MAC_Bench/Nature/Cover/Nature Chemistry/11_5.png,MAC_Bench/Nature/Cover/Nature Chemistry/11_5.png,clip,11_5.txt,train90Nature Reviews Chemistry,8_2,Which of the following options best describe the cover story?,"The depolymerization of lignin is represented by a wooden block at the centre of the image surrounded by the products of breakdown and catalysts that have been applied in this important biomass valorization reaction. Lignin is a heterogeneous aromatic macromolecule found in the cell walls of plants. Its conversion to useful monomers is considered key to a transition away from fossil fuel feedstocks. Although there has been much research into C-O cleavage, commercial use of a far greater proportion of available lignin requires cleavage of C-C bonds, which has proven particularly challenging both to develop and to quantify, see Palumbo et al.91Image: Rita Clare; Cover design: Carl Conway",A,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_2.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_8.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_8.png,vith,7_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/1_6.png,clip,1_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_11.png,MAC_Bench/Nature/Cover/Nature Reviews Chemistry/7_11.png,vitg,7_11.txt,train92ACS ES&T Water,2024_3,Which of the following options best describe the cover story?,The superior sensitivity and specificity of qPCR allow for the quantification of algal genera and the discovery of algae response to reservoir characteristics that traditional microscopy methods could not easily detect.,A,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_11.png,vith,2024_11.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_5.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,vitg,2025_1.txt,train93Nature Computational Science,4_2,Which of the following options best describe the cover story?,"Impact of generative AI on e-waste94The rising popularity and usage of generative artificial intelligence (AI) amongst the general public and for research purposes has contributed to an increase in electronic waste (e-waste). In this issue, Peng Wang and colleagues propose a computational framework to quantify the amount of e-waste that is produced by generative AI, particularly large language models, highlighting the potential for rapid e-waste growth under different scenarios and emphasizing the need for circular economies and proactive e-waste management strategies.95See Peng Wang et al. and Loïc Lannelongue96Image: Guillaume Payen / LightRocket / Getty Images. Cover design: Alex Wing.",A,MAC_Bench/Nature/Cover/Nature Computational Science/4_2.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_2.png,groundtruth,4_2.txt,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,MAC_Bench/Nature/Cover/Nature Computational Science/4_8.png,vitg,4_8.txt,MAC_Bench/Nature/Cover/Nature Computational Science/3_12.png,MAC_Bench/Nature/Cover/Nature Computational Science/3_12.png,clip,3_12.txt,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,MAC_Bench/Nature/Cover/Nature Computational Science/5_1.png,vith,5_1.txt,test97Trends in Endocrinology & Metabolism,35_6,Which of the following options best describe the cover story?,"This month we are celebrating Cell’s 50th anniversary by focusing on98the exciting metabolic research that Cell Press publishes across its titles. This99month’s100covers of Cell Metabolism, Cell and Trends in Endocrinology & Metabolism, when put side-by-side, form a single image, reflective of the variety of topics101on metabolic102research that you will find across the three journals and the connections between103them.104Our cover reflects some of the contents of this issue, spanning from chronotherapy105in cardiovascular care (Festus et al, pp 607–623) to beta cell senescence in type 1106and type 2 diabetes (Morelli et al, pp 576–585), to fetal outcomes in maternal obesity107(Zhang et al, 638–647) and more. Artwork credit: Sonhita Chakraborty",A,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_6.png,groundtruth,35_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/27_6.png,vith,27_6.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_3.png,clip,35_3.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/28_6.png,vitg,28_6.txt,train108ACS ES&T Air,2024_9,Which of the following options best describe the cover story?,An inverse modeling approach is developed to refine emission inventories and enhance air quality prediction by a combined use of PM2.5 data measured by a high-grade accurate instrument in the US embassy with low-cost PurpleAir sensor data from citizens for such developing countries as in Ethiopia where a national air quality observation network does not exist. Image generated by DALL·E 3 (OpenAI) and modified using Clip Studio.,B,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,ave_2,2024_3.txt,train109ACS Synthetic Biology,2024_6,Which of the following options best describe the cover story?,This cover describes a method of metabolic engineering for the production of ectoine based on the heterologous expression of ectoine synthesis-related genes in Corynebacterium glutamicum to increase ectoine production.,B,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_2.png,ave_3,2015_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_11.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2015_11.png,vitg,2015_11.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_5.png,clip,2024_5.txt,test110Science Robotics,10_99,Which of the following options best describe the cover story?,"ONLINE COVER Biohybrid Robots—Controlling Robotic Hand Movement with Muscle Tissue. Biohybrid robots provide the advantage of combining muscle tissue derived from cells as well as synthetic components. These muscle tissues can be controlled to generate contractile forces necessary to provide linear movement of joints. Ren et al. have developed a multifingered robotic hand that was powered by bundles of muscle tissue. The muscles were connected to tendons and ultimately to the individual fingers, which could be controlled independently to generate flexion when exposed to electrical stimulation. This month’s cover is an image of the biohybrid robotic hand showing the fingers in flexion. Credit: : Shoji Takeuchi research group/University of Tokyo",C,MAC_Bench/Science/Cover/Science Robotics/10_98.png,MAC_Bench/Science/Cover/Science Robotics/10_98.png,vith,10_98.txt,MAC_Bench/Science/Cover/Science Robotics/5_46.png,MAC_Bench/Science/Cover/Science Robotics/5_46.png,clip,5_46.txt,MAC_Bench/Science/Cover/Science Robotics/10_99.png,MAC_Bench/Science/Cover/Science Robotics/10_99.png,groundtruth,10_99.txt,MAC_Bench/Science/Cover/Science Robotics/7_67.png,MAC_Bench/Science/Cover/Science Robotics/7_67.png,vitg,7_67.txt,train111Nature Reviews Physics,6_11,Which of the following options best describe the cover story?,"The cover of this issue illustrates the search for an island of nuclear stability, a metaphor that has by now shifted towards glimpsing the mountains of enhanced stability on the horizon, their tops still concealed by clouds. See >[Smits] et al.112Cover design: Susanne Harris.",B,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_1.png,vith,4_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_11.png,groundtruth,6_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_5.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_5.png,vitg,4_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_9.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/5_9.png,clip,5_9.txt,test113NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_2,Which of the following options best describe the cover story?,"‘Gates and channels’, inspired by the Reviews on p904 and p886114Cover design: Vicky Summersby",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/24_6.png,clip,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_2.png,ave_2,26_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,vitg,26_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_2.png,groundtruth,25_2.txt,test115Trends in Cognitive Sciences,28_8,Which of the following options best describe the cover story?,"Developing tests that could be used to detect consciousness in immature116and non-responsive humans, non-human animals, brain organoids, and AI systems is117one of the central challenges facing science. Addressing this challenge would not118only119have important implications for the science of consciousness but would also have120profound ethical and social implications. In this issue of Trends in Cognitive Sciences,121Tim Bayne and colleagues review some of the leading tests for consciousness that122have been developed to date, clarify the logical structure of various possible tests123for124consciousness, and critically evaluate three strategies for validating a consciousness125test. The cover image depicts two of the many kinds of organisms to which a test for126consciousness might be applied. Cover art by James Croxford.",B,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_6.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_6.png,ave_1,20_6.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_8.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_8.png,groundtruth,28_8.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_1.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/20_1.png,vitg,20_1.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/26_5.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/26_5.png,clip,26_5.txt,test127Cell Systems,15_8,Which of the following options best describe the cover story?,"On the cover: VelvetSDE simulations of early neural progenitors differentiating into128motor neurons, V3 interneurons, and floor plate cells, coloured by fate and visualised129in PCA space of VelvetSDE latent space representation. Maizels et al. present methods for dynamical modeling from single-cell transcriptomics: an experimental130protocol for metabolic labeling that provides increased data quality with single-cell131temporal resolution and a generative modeling framework for velocity inference that132outperforms other tools and provides trajectory simulations that capture dynamical133aspects of cell fate decisions. Image credit: the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/15_8.png,MAC_Bench/Cell/Cover/Cell Systems/15_8.png,groundtruth,15_8.txt,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,ave_1,4_4.txt,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,clip,1_5.txt,train134Nature Astronomy,9_1,Which of the following options best describe the cover story?,"Galactic fireworks from cosmic dawn13513.4-billion-year-old photons reveal the extreme conditions in one of the most distant known galaxies. This illustration highlights the JWST/MIRI spectrum of galaxy GHZ2/GLASS-z12, in which atomic transitions from hydrogen and oxygen are present.136See Zavala et al.137Image: César Augusto Huato Méndez & Jorge A. Zavala (Background image: JWST, NASA/ESA/CSA. Composition by Diego Paris). Cover design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Astronomy/9_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/4_11.png,MAC_Bench/Nature/Cover/Nature Astronomy/4_11.png,clip,4_11.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,vitg,2_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,ave_3,1_1.txt,train138ACS ES&T Engineering,2024_12,Which of the following options best describe the cover story?,This special issue showcases the latest research in the application of computational modeling in environmental research. The front cover shows that the density functional theory (DFT) calculation of aperiodic small molecule systems is a cost-effective and promising approach for investigating the reaction mechanisms of advanced oxidation processes at the subatomic level,A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_12.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,vitg,2023_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_3.png,clip,2023_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_11.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_11.png,vith,2022_11.txt,train139CELL RESEARCH,34_8,Which of the following options best describe the cover story?,"The image illustrates a Chinese historical story, depicting Taigong Jiang fishing with his hook, reminiscent of the innovative proximity labeling tool, PhastID. PhastID identifies ATP6AP1, an unconventional GEF of Rheb. The C-tail at the end of ATP6AP1 can be used as a switch for Rheb to regulate the activation of mTORC1 signaling. Just as the two different states of the fish in the image, activating Rheb or not has distinct impacts on cellular functions. See page 355–369 by Ran Feng et al. for details.",A,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_8.png,groundtruth,34_8.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_1.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_1.png,ave_3,32_1.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png,ave_2,34_7.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_3.png,clip,34_3.txt,train140Cell Systems,16_1,Which of the following options best describe the cover story?,"On the cover: Heatmap of temporal activity of ERK, measured using the modified ERK141kinase translocation reporter (KTR) and read out as cytoplasmic:nuclear ratio in thousands142of single A375 cells, before and after treatment with 10 nM Trametinib indicated by143the black line. In this issue of Cell Systems, Hoffman et al. find that ERK and p38 KTRs can be partly phosphorylated by CDK2, a phenomenon unmasked144under MAPK pathway inhibition. The authors show that the modified FRET-based sensor,145EKAREN5, does not show this crosstalk and that, by co-expressing the ERK or p38 KTR146with the CDK2 sensor, contributions of CDK2 activity on the KTR signals can be removed.147Image credit: the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/16_1.png,MAC_Bench/Cell/Cover/Cell Systems/16_1.png,groundtruth,16_1.txt,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,MAC_Bench/Cell/Cover/Cell Systems/7_2.png,vitg,7_2.txt,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,MAC_Bench/Cell/Cover/Cell Systems/11_2.png,vith,11_2.txt,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,clip,1_2.txt,train148ACS Chemical Neuroscience,2024_11,Which of the following options best describe the cover story?,"Ligands with multipotent profile binding with different targets, such as acetylcholine esterase, monoamine oxidase, and amyloid β: Multipotent ligands are expected to display neuroprotection and neurorescue potential along with reactive species inhibition activity for the effective treatment of Alzheimer’s disease.",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_11.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2018_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2018_6.png,clip,2018_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_13.png,ave_0,2021_13.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_10.png,vitg,2022_10.txt,train149Trendsin Neurosciences,47_3,Which of the following options best describe the cover story?,"Left-right asymmetry in brain function and neuronal circuits is a conserved150feature among bilaterians, playing crucial roles in perception, cognition, and behavior.151In this issue of Trends in Neurosciences, François Lapraz, Cloé Fixary-Schuster, and152Stéphane Noselli explore recent findings in nematode, zebrafish, and Drosophila153models, highlighting the relationship between body and brain asymmetries and the154evolutionary conservation of laterality mechanisms and function. The cover image155showcases asymmetrical Drosophila H-neurons overlayed onto a reference brain156(fruitfly.tefor.net). It features a composite of single neuron clones, with one left157(magenta) and one right (cyan) H-neuron sending projections specifically into the158right159asymmetrical body, with no projection to the left one. Cover image acquired by Céline160Boutres and designed by François Lapraz, Cloé Fixary-Schuster, and Stéphane Noselli.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_3.png,groundtruth,47_3.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/41_3.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/41_3.png,clip,41_3.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,vitg,43_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_6.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_6.png,vith,43_6.txt,test161ACS Materials Au,2024_2,Which of the following options best describe the cover story?,"The modern semiconductor industry highly demands efficient photoresists suitable to EUV nanolithography. Yoon and colleagues synthesized a novel macrocyclic multinuclear tin complex and conducted an in-depth investigation into its photochemical behavior. The photoresist exhibited small line-edge roughness in EUV lithography, underscoring its potential as an efficient EUV photoresist. AI was used in the creation of the cover image.",A,MAC_Bench/ACS/Cover/ACS Materials Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_4.png,clip,2023_4.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,MAC_Bench/ACS/Cover/ACS Materials Au/2023_2.png,ave_2,2023_2.txt,MAC_Bench/ACS/Cover/ACS Materials Au/2022_6.png,MAC_Bench/ACS/Cover/ACS Materials Au/2022_6.png,vitg,2022_6.txt,train162Med,5_12,Which of the following options best describe the cover story?,"On the cover: Many human diseases display variations in their phenotypic manifestation,163which can be attributed to a complex interplay between underlying genetic factors.164In this issue, Levine et al. utilize data from the Human Phenotype Project to map the genetic correlates associated165with traits such as blood sugar levels and sleep quality, providing higher-resolution166links to disease than simple clinical diagnoses. This work suggests that phenotypic167associations may be useful in detecting disease-linked genetic signals before the168threshold for a clinical diagnosis is crossed and offers publicly accessible tools169to further map the exact genetic mechanisms underlying various aspects of human health170and disease. Cover art from Boris SV/Moment via Getty Images.",B,MAC_Bench/Cell/Cover/Med/5_3.png,MAC_Bench/Cell/Cover/Med/5_3.png,vitg,5_3.txt,MAC_Bench/Cell/Cover/Med/5_12.png,MAC_Bench/Cell/Cover/Med/5_12.png,groundtruth,5_12.txt,MAC_Bench/Cell/Cover/Med/5_7.png,MAC_Bench/Cell/Cover/Med/5_7.png,vith,5_7.txt,MAC_Bench/Cell/Cover/Med/4_2.png,MAC_Bench/Cell/Cover/Med/4_2.png,clip,4_2.txt,train171NATURE GENETICS,56_9,Which of the following options best describe the cover story?,"Coffea arabica diversification history172Genome assemblies of allotetraploid Coffea arabica and representatives of its diploid progenitors provide insights into diversification history.173See Salojärvi et al.174Image: Amanda van der Sijs/500px/Getty. Cover design: Tulsi Voralia",A,MAC_Bench/Nature/Cover/NATURE GENETICS/56_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_9.png,groundtruth,56_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/49_9.png,MAC_Bench/Nature/Cover/NATURE GENETICS/49_9.png,vitg,49_9.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/56_11.png,MAC_Bench/Nature/Cover/NATURE GENETICS/56_11.png,clip,56_11.txt,MAC_Bench/Nature/Cover/NATURE GENETICS/53_1.png,MAC_Bench/Nature/Cover/NATURE GENETICS/53_1.png,vith,53_1.txt,test175ACS Applied Polymer Materials,2024_18,Which of the following options best describe the cover story?,"niversal controlled-release system based on cubosome-carrying bacterial cellulose capsules with a pH-smart trigger mechanism for the oral administration of therapeutic bioactives is rationally designed. Site-specific, dual cargo-controlled release is achieved through a solubility-dependent phenomenon. Such an engineered pH-responsive microcapsule has potential for colon-targeted multidrug delivery.",B,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_1.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2022_1.png,ave_2,2022_1.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_18.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2020_12.png,ave_3,2020_12.txt,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,MAC_Bench/ACS/Cover/ACS Applied Polymer Materials/2025_2.png,clip,2025_2.txt,train176Nature Cardiovascular Research,3_2,Which of the following options best describe the cover story?,"Sleep and atherosclerosis177Kiss et al. review preclinical and clinical evidence that illustrates how sleep influences the nervous, metabolic and immune systems, with inadequate sleep affecting the risk of atherosclerotic cardiovascular disease.178See Kiss et al.179Image: Siesta, Henri Manguin – Heritage Image Partnership / Alamy Stock Photo. Cover design: Bethany Vukomanovic",B,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,vitg,2_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_2.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_2.png,groundtruth,3_2.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_6.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_6.png,ave_3,3_6.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_3.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_3.png,clip,3_3.txt,train180Nature Nanotechnology,19_8,Which of the following options best describe the cover story?,"Flexible tandem light-emitting diodes181The cover image depicts a flexible 10 × 10 matrix of narrow-band and high-efficiency green tandem light-emitting diodes, combining nanocrystal perovskite light-emitting diode and organic light-emitting diode units.182See Lee et al.183Image: Tae-Woo Lee / Seoul National University. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Nanotechnology/15_1.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/15_1.png,vith,15_1.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_8.png,groundtruth,19_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_9.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_9.png,vitg,18_9.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,train184Structure,32_3,Which of the following options best describe the cover story?,"On the cover: Synaptotagmin-1 C2A and C2B domains bind to model lipid bilayers mimicking185the synaptic plasma membrane (C2B) and the synaptic vesicle membrane (C2A). A native186mass spectrum of Synaptotagmin-1 binding to DOPS at different stoichiometries is shown187below the plasma membrane plane. Bender et al. combined native mass spectrometry and protein-lipid binding assays with molecular188dynamics simulations to investigate the lipid preferences of the two Synaptotagmin-1189C2 domains. Image credit: Julian Bender.",C,MAC_Bench/Cell/Cover/Structure/32_11.png,MAC_Bench/Cell/Cover/Structure/32_11.png,vitg,32_11.txt,MAC_Bench/Cell/Cover/Structure/28_11.png,MAC_Bench/Cell/Cover/Structure/28_11.png,clip,28_11.txt,MAC_Bench/Cell/Cover/Structure/32_3.png,MAC_Bench/Cell/Cover/Structure/32_3.png,groundtruth,32_3.txt,MAC_Bench/Cell/Cover/Structure/24_12.png,MAC_Bench/Cell/Cover/Structure/24_12.png,vith,24_12.txt,train190NATURE MATERIALS,23_12,Which of the following options best describe the cover story?,"Magnetoelectric metamaterials for neurostimulation191Self-rectifying magnetoelectric metamaterials with nonlinear responses generate electrical pulse sequences that enable precisely timed remote neural stimulation and restoration of sensory motor responses in vivo.192See Chen et al.193Image: Maayan Harel. Cover design: Alex Whitworth",C,MAC_Bench/Nature/Cover/NATURE MATERIALS/9_7.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/9_7.png,clip,9_7.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_7.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_12.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_12.png,groundtruth,23_12.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_4.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/19_4.png,vitg,19_4.txt,train194Trends in Immunology,45_1,Which of the following options best describe the cover story?,"On pages 971–986, Jorfi, Tanzi, and colleagues discuss the role peripheral195immune cells play in contributing to Alzheimer’s disease (AD) pathology, and recent196approaches for studying neuroimmune interactions. The illustration depicts a human197brain where half includes forget-me-not flowers (symbols of AD) that are floating198away.199Therapeutically targeting peripheral immune cells might contribute to ameliorating200AD201and preserving memory. The artist wanted to suggest that the person facing the bright202light looks at a hopeful.",C,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,ave_3,36_4.txt,MAC_Bench/Cell/Cover/Trends in Immunology/38_2.png,MAC_Bench/Cell/Cover/Trends in Immunology/38_2.png,vitg,38_2.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_1.png,groundtruth,45_1.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,clip,36_3.txt,train203Nature Chemistry,16_3,Which of the following options best describe the cover story?,"Solid-state superionic conductivity204All-solid-state batteries offer a safer alternative to conventional lithium-ion batteries, but the solid electrolytes necessary to transport lithium ions between electrodes display poor room-temperature conductivities. Now, Jue Liu, Yifei Mo, and Hailong Chen show how a family of electrolyte solids undergo a temperature-triggered transition from low to high conductivities due to collective anion motion. Using the uncovered structure–property relationships, they develop new electrolytes with lower transition temperatures to achieve superionic conductivities at room temperature. The cover shows an artistic representation of lithium-ion movement through the solid-state electrolyte.205See Chen et al.206Image: Phoenix Pleasant / ORNL, U.S. Dept. of Energy. Cover design: Tulsi Voralia",D,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/6_1.png,MAC_Bench/Nature/Cover/Nature Chemistry/6_1.png,vitg,6_1.txt,MAC_Bench/Nature/Cover/Nature Chemistry/9_4.png,MAC_Bench/Nature/Cover/Nature Chemistry/9_4.png,vith,9_4.txt,MAC_Bench/Nature/Cover/Nature Chemistry/16_3.png,MAC_Bench/Nature/Cover/Nature Chemistry/16_3.png,groundtruth,16_3.txt,train207Journal of the American Chemical Society,2024_27,Which of the following options best describe the cover story?,A novel carbene-assisted strategy for arene ring-opening is demonstrated. Experiments and DFT calculations have validated that both diazo and non-diazo carbene precursors could effectively initiate the reactions to afford value-added extended conjugated molecules. This chemistry expands the horizons of carbene chemistry and provides a novel pathway for arene ring-opening.,A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_27.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_27.png,groundtruth,2024_27.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_27.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_27.png,vith,2010_27.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2010_30.png,vitg,2010_30.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2020_37.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2020_37.png,clip,2020_37.txt,train208Joule,8_3,Which of the following options best describe the cover story?,"On the cover: The cover image features an all-solid-state battery (ASSB) incorporating209an FeSn2 anode, a LiNi0.6Co0.2Mn0.2O2 (NCM622) cathode, and a Li6PS5Cl solid electrolyte placed on an electronic circuit. The continents of the Earth210are illuminated by the energy generated from this high-energy-density ASSB, symbolizing211its potential to revolutionize global energy storage and utilization. As demonstrated212by Lee et al., this ASSB exhibits exceptional performance, stability, and energy efficiency, emphasizing213its crucial role in advancing sustainable energy for the future. This pioneering research214highlights the potential of FeSn2 anodes to enhance the overall performance and safety of ASSBs, driving innovation215in energy storage technology. Artist/image source: Suk-Woo Yoon (SCIART 3D GRAPHIC216in Republic of Korea).",A,MAC_Bench/Cell/Cover/Joule/8_3.png,MAC_Bench/Cell/Cover/Joule/8_3.png,groundtruth,8_3.txt,MAC_Bench/Cell/Cover/Joule/4_6.png,MAC_Bench/Cell/Cover/Joule/4_6.png,clip,4_6.txt,MAC_Bench/Cell/Cover/Joule/5_8.png,MAC_Bench/Cell/Cover/Joule/5_8.png,vitg,5_8.txt,MAC_Bench/Cell/Cover/Joule/2_6.png,MAC_Bench/Cell/Cover/Joule/2_6.png,vith,2_6.txt,train217Nature Plants,10_8,Which of the following options best describe the cover story?,"Generating gametangia218Bryophytes, such as the model liverwort Marchantia polymorpha, develop sexual organs known as gametangia. The ‘non-canonical’ transcription factor MpBZR3 is involved in regulating both male and female structures, antheridia and archegonia respectively. Overexpression of MpBZR3 induces ectopic development of multiple gametangia.219See Furuya et al.220Image: Tomoyuki Furuya, Ritsumeikan University. Cover design: Erin Dewalt",C,MAC_Bench/Nature/Cover/Nature Plants/9_2.png,MAC_Bench/Nature/Cover/Nature Plants/9_2.png,vith,9_2.txt,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,MAC_Bench/Nature/Cover/Nature Plants/5_3.png,vitg,5_3.txt,MAC_Bench/Nature/Cover/Nature Plants/10_8.png,MAC_Bench/Nature/Cover/Nature Plants/10_8.png,groundtruth,10_8.txt,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,clip,4_6.txt,test221Biophysical Journal,124_3,Which of the following options best describe the cover story?,"Cover picture: Inhibition of the Brahma-related gene (BRG1) motor in the Brg/Brm-associated factor222chromatin remodeling complex stiffens the nucleus, preventing its transition from223an oblate shape in substrate-attached cells to a spherical shape in plasma-membrane-enclosed224karyoplasts upon isolation. When fibroblasts with active BRG1 are exposed to gentle225centrifugal forces, they lose most of their nuclei, leaving behind nucleus-free cytoplasts.226In contrast, when the BRG1 motor is inhibited (as shown in this image), the same centrifugal227force leaves behind mostly intact cells and fewer cytoplasts (actin cytoskeleton stained228in green), with their nuclei (blue) unable to emerge from the cell during the centrifugation process. DOI: https://doi.org/10.1016/j.bpj.2024.11.3322.",A,MAC_Bench/Cell/Cover/Biophysical Journal/124_3.png,MAC_Bench/Cell/Cover/Biophysical Journal/124_3.png,groundtruth,124_3.txt,MAC_Bench/Cell/Cover/Biophysical Journal/111_1.png,MAC_Bench/Cell/Cover/Biophysical Journal/111_1.png,vitg,111_1.txt,MAC_Bench/Cell/Cover/Biophysical Journal/112_10.png,MAC_Bench/Cell/Cover/Biophysical Journal/112_10.png,vith,112_10.txt,MAC_Bench/Cell/Cover/Biophysical Journal/101_11.png,MAC_Bench/Cell/Cover/Biophysical Journal/101_11.png,clip,101_11.txt,train229NATURE REVIEWS MICROBIOLOGY,22_8,Which of the following options best describe the cover story?,"Alternatives for treating antibiotic-resistant pathogens, inspired by the Review on p262.230Cover design: Philip Patenall.",D,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,ave_0,20_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,vith,19_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png,groundtruth,22_8.txt,train231Cell Genomics,4_12,Which of the following options best describe the cover story?,"On the cover: In this issue of Cell Genomics, Wu et al. present an innovative approach to non-invasively quantify extracellular RNA (exRNA)232extracted from the spent culture media of human in vitro fertilization (IVF) embryos. The cover art ingeniously captures the study's essence,233envisioning the temporal fluctuations of exRNA resembling majestic mountains while234depicting embryos as celestial stars. Crafted by Yuan Liu, this image encapsulates235the intricate interplay between exRNA dynamics and the developmental journey of embryos.",B,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,vitg,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,groundtruth,4_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_3.png,MAC_Bench/Cell/Cover/Cell Genomics/4_3.png,vith,4_3.txt,val236Cell Systems,15_7,Which of the following options best describe the cover story?,"On the cover: Illustration showing simulations of tumor growth arranged as the two237strands of a DNA helix, shattered by the emblematic double strand break induced by238PARP inhibitors. The simulations (strands) compare two adaptive strategies: as the239tumor responds and regrows under treatment (blue lines), doses are either modulated240or skipped (shading and bars, with some artistic liberties). In this issue of Cell Systems, Strobl et al. integrate real-time microscopy and mathematical modeling to investigate whether adaptive241therapy, which dynamically tailors treatment to the tumor dynamics, could help to242reduce cumulative PARP inhibitor use to reduce toxicity. Image credit: Kit Gallagher243and the authors.",A,MAC_Bench/Cell/Cover/Cell Systems/15_7.png,MAC_Bench/Cell/Cover/Cell Systems/15_7.png,groundtruth,15_7.txt,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,MAC_Bench/Cell/Cover/Cell Systems/4_4.png,vitg,4_4.txt,MAC_Bench/Cell/Cover/Cell Systems/1_3.png,MAC_Bench/Cell/Cover/Cell Systems/1_3.png,ave_2,1_3.txt,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,MAC_Bench/Cell/Cover/Cell Systems/1_5.png,clip,1_5.txt,train244Nature Human Behaviour,8_3,Which of the following options best describe the cover story?,"Connecting humans and machines245The ubiquity of human–machine interactions is an opportunity to explore, while being mindful of the risks. This issue features a Focus on the many ways in which humans interact and communicate with machines, which foregrounds the societal implications and ethical considerations of emerging technologies.246See Focus247Image: Bethany Vukomanovic. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_11.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/6_11.png,ave_2,6_11.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/7_4.png,clip,7_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_3.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_3.png,groundtruth,8_3.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_2.png,vitg,4_2.txt,test248Science Advances,11_1,Which of the following options best describe the cover story?,"ONLINE COVER The crescent Earth rises above the lunar horizon in this photograph taken from the Apollo 17 spacecraft in lunar orbit during the final lunar landing mission in the Apollo program. The evolution of the lunar magnetic field helps explain the Moon’s interior structure, thermal history, and surface environment. Using mare basalt samples from the Moon’s Oceanus Procellarum at midlatitude, gathered from the Chang’e-5 mission, Cai et al. describe the existence of a weak lunar dynamo 2 billion years ago. Their findings also suggest an alternative mechanism for the origin of the young lunar volcanism. These details will help shape studies of lunar space weathering and volatile materials. Credit: NASA/JSC",D,MAC_Bench/Science/Cover/Science Advances/9_5.png,MAC_Bench/Science/Cover/Science Advances/9_5.png,clip,9_5.txt,MAC_Bench/Science/Cover/Science Advances/10_4.png,MAC_Bench/Science/Cover/Science Advances/10_4.png,vitg,10_4.txt,MAC_Bench/Science/Cover/Science Advances/9_27.png,MAC_Bench/Science/Cover/Science Advances/9_27.png,vith,9_27.txt,MAC_Bench/Science/Cover/Science Advances/11_1.png,MAC_Bench/Science/Cover/Science Advances/11_1.png,groundtruth,11_1.txt,train249Matter,7_4,Which of the following options best describe the cover story?,"On the cover: This month's cover from Hsu and colleagues depicts a red-colored biomaterials film wrapped in a spiral pattern to look like250a rose, sitting in a menstrual cup. The work describes the development of an eco-friendly,251blood-absorbent biomaterial that improves the performance of menstrual products by252minimizing blood leakage and spilling while also helping to prevent infection. The253stark cover counters the stigma of thinking or studying menstruation, using advanced254functional materials for innovative solutions. Image courtesy of the authors.",B,MAC_Bench/Cell/Cover/Matter/6_2.png,MAC_Bench/Cell/Cover/Matter/6_2.png,vith,6_2.txt,MAC_Bench/Cell/Cover/Matter/7_4.png,MAC_Bench/Cell/Cover/Matter/7_4.png,groundtruth,7_4.txt,MAC_Bench/Cell/Cover/Matter/7_3.png,MAC_Bench/Cell/Cover/Matter/7_3.png,clip,7_3.txt,MAC_Bench/Cell/Cover/Matter/3_2.png,MAC_Bench/Cell/Cover/Matter/3_2.png,vitg,3_2.txt,train255ACS Earth and Space Chemistry,2024_6,Which of the following options best describe the cover story?,"Wildfire particulate matter is comprised of a complex mixture of chemical species such as organic carbon (OC), elemental carbon (EC), ions, polycyclic aromatic hydrocarbons (PAHs), and metals. Prevailing winds can transport fresh plumes to urban centers thousands of kilometers away from the burning site, and secondary processing may change the chemical composition during transport.",B,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,vitg,2022_11.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_6.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_10.png,ave_1,2024_10.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,clip,2022_10.txt,train256Developmental Cell,59_12,Which of the following options best describe the cover story?,"On the cover: These confocal images of Drosophila larval salivary gland nuclei show the distinctive banding pattern of the large, highly257polytene chromosomes (stained with Hoechst in magenta and orange). Chromatin status258is visualised using antibodies for Histone 3 lysine 4 tri-methylation (cyan). The259large size of these nuclei makes them ideal for studying transcription factor behavior.260To learn more about the biophysical behaviour of transcription effectors of the Hippo261pathway, see Manning et al. Image credit: Samuel Manning.",A,MAC_Bench/Cell/Cover/Developmental Cell/59_12.png,MAC_Bench/Cell/Cover/Developmental Cell/59_12.png,groundtruth,59_12.txt,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,MAC_Bench/Cell/Cover/Developmental Cell/40_4.png,vith,40_4.txt,MAC_Bench/Cell/Cover/Developmental Cell/56_10.png,MAC_Bench/Cell/Cover/Developmental Cell/56_10.png,clip,56_10.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,MAC_Bench/Cell/Cover/Developmental Cell/59_7.png,vitg,59_7.txt,train262Trends in Plant Science,29_10,Which of the following options best describe the cover story?,"An in-depth analysis of the mechanistic processes underlying the evolution and ecophysiology263of typical invasive plants such as Carpobrotus spp., Acacia spp., Agave spp. and Opuntia spp. (shown on the cover) in Mediterranean-type ecosystems shows very sophisticated,264complex, and efficient strategies for invasion success, particularly in fragmented265habitats. Sergi Munné-Bosch proposes a two-pronged strategy based on long-term prevention266and eradication for the management of Mediterranean-type ecosystems. Image credit:267Sergi Munné-Bosch.",A,MAC_Bench/Cell/Cover/Trends in Plant Science/29_10.png,MAC_Bench/Cell/Cover/Trends in Plant Science/29_10.png,groundtruth,29_10.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/22_1.png,MAC_Bench/Cell/Cover/Trends in Plant Science/22_1.png,ave_2,22_1.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/26_9.png,MAC_Bench/Cell/Cover/Trends in Plant Science/26_9.png,clip,26_9.txt,MAC_Bench/Cell/Cover/Trends in Plant Science/26_5.png,MAC_Bench/Cell/Cover/Trends in Plant Science/26_5.png,vitg,26_5.txt,val268Nature Reviews Endocrinology,20_6,Which of the following options best describe the cover story?,"The individual response to antibiotics and diet, inspired by the Review on p387.269Cover design: Jennie Vallis",A,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,groundtruth,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_2.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/17_2.png,ave_2,17_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/18_12.png,vith,18_12.txt,train270Nature Food,5_12,Which of the following options best describe the cover story?,"Urban agriculture271Urban food systems still rely almost entirely on imported goods and services. The acceleration of urbanization is therefore expected to place greater demands on resources that are already strained by shifting land use, rising inequalities and climate change. Urban agriculture represents a promising lever to reduce this pressure while inducing a broader transformative change towards urban resilience and sustainability. Scaling up urban agriculture will need to address diversity, heterogeneity, connectivity, spatial synergies and trade-offs, nonlinearity, scale and polycentricity. This transition could prompt the decentralization of urban food supplies, bolster ecosystem services, mitigate transboundary environmental footprints and advance urban resilience. Multi-phase developmental pathways, including dynamics, accelerators and feedback associated with scaling up urban agriculture, should be considered in support of food security for the growing urban population.272See Qiu et al.273Image: Lim Weixiang - Zeitgeist Photos/E+/Getty. Cover Design: Tulsi Voralia.",C,MAC_Bench/Nature/Cover/Nature Food/3_11.png,MAC_Bench/Nature/Cover/Nature Food/3_11.png,ave_3,3_11.txt,MAC_Bench/Nature/Cover/Nature Food/2_7.png,MAC_Bench/Nature/Cover/Nature Food/2_7.png,vitg,2_7.txt,MAC_Bench/Nature/Cover/Nature Food/5_12.png,MAC_Bench/Nature/Cover/Nature Food/5_12.png,groundtruth,5_12.txt,MAC_Bench/Nature/Cover/Nature Food/3_4.png,MAC_Bench/Nature/Cover/Nature Food/3_4.png,clip,3_4.txt,train274Nature Geoscience,17_11,Which of the following options best describe the cover story?,"Emergence of the Antarctic Circumpolar Current275Ocean sediment records indicate that the modern Antarctic Circumpolar Current did not exist prior to climatic cooling in the Late Miocene, suggesting an origin linked to the expansion of the Antarctic Ice Sheet. The image shows Spanish polar research vessel BIO Hespérides (A-33) offshore Livingston Island in the South Shetlands Archipelago, Antarctic Peninsula.276See Evangelinos et al.277Image: José-Abel Flores, University of Salamanca. Cover Design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/9_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/9_7.png,vith,9_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_7.png,clip,14_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_11.png,groundtruth,17_11.txt,MAC_Bench/Nature/Cover/Nature Geoscience/6_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_11.png,ave_2,6_11.txt,train278ACS Chemical Neuroscience,2024_12,Which of the following options best describe the cover story?,ᴅ-glucose ([18F]FDG) PET imaging. [18F]FDG PET offers a quantitative and translational neuroimaging method to explore the CNS effects of candidate drugs for smoking cessation therapy.,A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_12.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_11.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_11.png,vitg,2020_11.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_15.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_15.png,vith,2024_15.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_13.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_13.png,clip,2022_13.txt,train279Molecular Pharmaceutics,2024_7,Which of the following options best describe the cover story?,Schematic graphical representation of multiple drug substances interacting inside a phospholipid bilayer while permeating from a liposome.,C,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_6.png,clip,2022_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_12.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_12.png,vitg,2024_12.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_7.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_4.png,ave_0,2020_4.txt,train280ACS Photonics,2024_6,Which of the following options best describe the cover story?,"An intelligent meta-device with a stereo vision meta-lens can provide a multimodal assisted driving vision by integrating the raw image, instance labels, bounding boxes, segmentation masks in depth pseudo color, and depth information for each detected object.",B,MAC_Bench/ACS/Cover/ACS Photonics/2024_10.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_10.png,vitg,2024_10.txt,MAC_Bench/ACS/Cover/ACS Photonics/2024_6.png,MAC_Bench/ACS/Cover/ACS Photonics/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Photonics/2020_3.png,MAC_Bench/ACS/Cover/ACS Photonics/2020_3.png,clip,2020_3.txt,MAC_Bench/ACS/Cover/ACS Photonics/2021_12.png,MAC_Bench/ACS/Cover/ACS Photonics/2021_12.png,vith,2021_12.txt,train281Nature Reviews Psychology,3_5,Which of the following options best describe the cover story?,"In this Review, Bell et al. describe current VR-based treatments for mental health conditions and discuss technological and psychological tools that might promote enhanced immersive experiences.282Cover design: David Johnston",C,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_7.png,clip,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_6.png,ave_2,1_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_5.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/3_5.png,groundtruth,3_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Psychology/1_9.png,vitg,1_9.txt,train283ACS Applied Engineering Materials,2024_1,Which of the following options best describe the cover story?,"The ACS AMI Family “2024 Early Career Forum” highlights groundbreaking research and innovative ideas from the emerging authors in the scientific community on a broad range of topics. This edition of the Forum showcases 135 exceptional contributions from early-career scientists worldwide, published across ACS Applied Materials & Interfaces, ACS Applied Bio Materials, ACS Applied Electronic Materials, ACS Applied Engineering Materials, ACS Applied Energy Materials, ACS Applied Nano Materials, ACS Applied Optical Materials, and ACS Applied Polymer Materials.",C,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_12.png,clip,2024_12.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_10.png,ave_1,2024_10.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Engineering Materials/2023_12.png,vith,2023_12.txt,train284Caner Cell,42_12,Which of the following options best describe the cover story?,"On the cover: Routy et al. review the microbiota research in the context of melanoma. The cover image demonstrates285the interplay between melanoma cancer cells and microbiota visually. An intricate286network of lines creates connections that symbolize the link between intestinal bacteria287and melanoma, highlighting the recent research included in the content, visually showcasing288the intricate relationship between the two. Image credit: Simon Rohlen, known as KEF!.",B,MAC_Bench/Cell/Cover/Caner Cell/23_5.png,MAC_Bench/Cell/Cover/Caner Cell/23_5.png,vitg,23_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_12.png,MAC_Bench/Cell/Cover/Caner Cell/42_12.png,groundtruth,42_12.txt,MAC_Bench/Cell/Cover/Caner Cell/21_3.png,MAC_Bench/Cell/Cover/Caner Cell/21_3.png,clip,21_3.txt,MAC_Bench/Cell/Cover/Caner Cell/30_5.png,MAC_Bench/Cell/Cover/Caner Cell/30_5.png,ave_1,30_5.txt,train289Current Biology,34_13,Which of the following options best describe the cover story?,"On the cover: A juvenile male rufous hummingbird (Selasphorus rufus) midflight in Vancouver, British Columbia. In this issue, Gaede et al. describe neural responses to tactile stimuli, including gusts of air, that may contribute290to the remarkable aerial abilities of hummingbirds. Using in vivo physiology in hummingbirds and finches, the authors reveal two distinct three-dimensional291maps in the avian forebrain that process touch, including areas corresponding to the292wings. Photograph by Duncan Leitch.",B,MAC_Bench/Cell/Cover/Current Biology/25_2.png,MAC_Bench/Cell/Cover/Current Biology/25_2.png,ave_2,25_2.txt,MAC_Bench/Cell/Cover/Current Biology/34_13.png,MAC_Bench/Cell/Cover/Current Biology/34_13.png,groundtruth,34_13.txt,MAC_Bench/Cell/Cover/Current Biology/20_22.png,MAC_Bench/Cell/Cover/Current Biology/20_22.png,vitg,20_22.txt,MAC_Bench/Cell/Cover/Current Biology/30_11.png,MAC_Bench/Cell/Cover/Current Biology/30_11.png,clip,30_11.txt,test293ACS Macro Letters,2024_10,Which of the following options best describe the cover story?,The more stretched bridging blocks and higher network connectivity in the self-assembled structure by the ABA triblock copolymer enable its superior mechanical performance over that by the ABC counterpart with a higher fraction of bridging block. Image Courtesy of Weihua Li.,B,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_9.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_9.png,vitg,2023_9.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_10.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2013_1.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2013_1.png,vith,2013_1.txt,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_8.png,MAC_Bench/ACS/Cover/ACS Macro Letters/2023_8.png,clip,2023_8.txt,train294Cancer Cell,42_2,Which of the following options best describe the cover story?,"On the cover: In their review, Galluzzi and colleagues examine the mechanisms by which malignant cells evade immune elimination through295a novel “three Cs” framework. Camouflage refers to cancer cells’ ability to disguise themselves from the immune system,296preventing recognition as a threat. Coercion involves the direct or indirect inhibition of immune functions by neoplastic297cells, while cytoprotection describes the capacity of malignant cells to withstand cytotoxic agents.298Together, these strategies contribute to immunoevasion and resistance to (immuno)therapy299across various oncological contexts.",C,MAC_Bench/Cell/Cover/Cancer Cell/20_1.png,MAC_Bench/Cell/Cover/Cancer Cell/20_1.png,vitg,20_1.txt,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,vith,23_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_2.png,MAC_Bench/Cell/Cover/Cancer Cell/42_2.png,groundtruth,42_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/40_3.png,MAC_Bench/Cell/Cover/Cancer Cell/40_3.png,clip,40_3.txt,train300Accounts of Chemical Research,2024_18,Which of the following options best describe the cover story?,"organic frameworks (2D c-MOFs) have emerged as a class of graphene-like materials with fully π-conjugated aromatic structures. Designing novel ligands is essential for the construction of new 2D c-MOFs with high crystallinity, excellent conductivity, and tailor-made functions.",B,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2021_17.png,vitg,2021_17.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_18.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_18.png,groundtruth,2024_18.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_7.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2019_7.png,vith,2019_7.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_17.png,clip,2024_17.txt,val301Lab Animal,54_1,Which of the following options best describe the cover story?,"Exploring the effects of electrical stunning on zebrafish larvae302Available methods for zebrafish euthanasia have limitations. In a new Article, Burkhardt et al. investigated the behavioral and neurophysiological effects of electrical stunning on zebrafish larvae, showing that rapid and reliable euthanasia can be achieved with this method.303See Burkhardt et al.304Cover image: Marina Spence. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Lab Animal/48_5.png,MAC_Bench/Nature/Cover/Lab Animal/48_5.png,vitg,48_5.txt,MAC_Bench/Nature/Cover/Lab Animal/48_2.png,MAC_Bench/Nature/Cover/Lab Animal/48_2.png,ave_1,48_2.txt,MAC_Bench/Nature/Cover/Lab Animal/54_1.png,MAC_Bench/Nature/Cover/Lab Animal/54_1.png,groundtruth,54_1.txt,MAC_Bench/Nature/Cover/Lab Animal/52_1.png,MAC_Bench/Nature/Cover/Lab Animal/52_1.png,clip,52_1.txt,train305Journal of Chemical Theory and Computation,2024_17,Which of the following options best describe the cover story?,"The extension of the Martini forcefield to glycosaminoglycans (GAGs, shown in red) enables coarse-grained simulation of more representative biological systems, such as the surface of cell membranes (yellow, green) where various proteoglycans and GAG-binding receptors (blue) are depicted.",C,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_7.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2022_7.png,vith,2022_7.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2018_12.png,clip,2018_12.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2021_12.png,vitg,2021_12.txt,test306Trends in Parasitology,41_1,Which of the following options best describe the cover story?,"The cover is the official logo of the 32nd National Congress of Parasitology307(NCP), Pune. The conference logo is inspired by Warli folk art, a tribal art originating308from309the Sahyadri range in Maharashtra, India. The logo is the visual representation of310the311theme of the conference, the impact of parasitic infections and vectors on both humans312and animals, with a One Health emphasis, and the need to take a holistic approach313to eliminate the burden of parasitic infections. In this issue of Trends in Parasitology,314Purkayastha et al. highlight the proceedings from the conference, which brought together315eminent parasitologists from India and also Africa to present and discuss their exciting316research from the field. Image credit: originally designed by Sindhuri Upadrasta and317further developed and digitally rendered by D.V. Mamatharani.",C,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,vith,31_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,clip,35_12.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/41_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/41_1.png,groundtruth,41_1.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,vitg,38_8.txt,train318Nature Food,5_4,Which of the following options best describe the cover story?,"Culturally acceptable diets319The EAT–Lancet reference diet provides guidance on how to simultaneously achieve environmental goals and improve human health. Yet, its wide-scale adoption requires attention to the cultural preferences and values of different populations around the world. In China, an ethnically and geographically diverse country, eating habits vary widely. A newly proposed region-specific reference diet aligned with local culinary traditions and preferences can reduce the environmental impact of food consumption and promote health beyond what would be achieved by adhering to other official dietary guidelines.320See Liu et al.321Image: wulingyun/Moment/Getty. Cover design: Laoise Mac Gabhann",D,MAC_Bench/Nature/Cover/Nature Food/2_10.png,MAC_Bench/Nature/Cover/Nature Food/2_10.png,clip,2_10.txt,MAC_Bench/Nature/Cover/Nature Food/3_4.png,MAC_Bench/Nature/Cover/Nature Food/3_4.png,vitg,3_4.txt,MAC_Bench/Nature/Cover/Nature Food/4_7.png,MAC_Bench/Nature/Cover/Nature Food/4_7.png,vith,4_7.txt,MAC_Bench/Nature/Cover/Nature Food/5_4.png,MAC_Bench/Nature/Cover/Nature Food/5_4.png,groundtruth,5_4.txt,train322Trends in Biochemical Sciences,49_11,Which of the following options best describe the cover story?,"The aberrant accumulation of amyloid structures is the underlying cause323of severe human diseases. However, the amyloid fold also plays a role in executing324specific biological functions. In the pages 119−133 of this issue, Garcia-Pardo and325Ventura discuss how the recent cryo-EM resolution revolution has enabled deciphering326the molecular intricacies of ribonucleoprotein amyloids, providing clues to rationalize327the dual involvement of this fold in normal protein function and disease pathology.328The cover art was designed by Dr. Javier Garcia-Pardo (@J_GarciaPardo) and Prof.329Dr. Salvador Ventura, and showcases a human brain, assembled from cryo-EM map330sections of hnRNPDL-2 amyloid fibrils (PDB 7ZIR) (@PPMC_UAB). Image from Ella331Maru Studio (@Ella_Maru).",B,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/40_1.png,clip,40_1.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_11.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_11.png,groundtruth,49_11.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_7.png,vith,45_7.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/47_14.png,vitg,47_14.txt,test332Science Translational Medicine,17_783,Which of the following options best describe the cover story?,"ONLINE COVER Manipulating Mitochondrial DNA. The cover shows a cross-section of a skeletal muscle fiber stained for cytochrome c oxidase activity (dark brown), an indicator of mitochondrial function, in a mouse treated with a mitochondrial DNA (mtDNA) base editor to correct a mutation in a mitochondrial tRNA. Mitochondrial disorders are often caused by mutations in mtDNA that are difficult to correct with traditional gene editing. Barrera-Paez et al. used a dose-dependent mitochondrial DddA-derived cytosine base editor (DdCBE) to successfully correct a mitochondrial tRNA mutation in mouse heart and muscle. However, at the highest doses of editing, DdCBE induced off-target DNA edits resulting in severe adverse effects in the mice. Together, the results suggest that DdCBE is a promising tool for mitochondrial gene editing, but caution is required to avoid dose-dependent adverse effects. Credit: Jose Domingo Barrera-Paez",B,MAC_Bench/Science/Cover/Science Translational Medicine/5_185.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_185.png,vitg,5_185.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_783.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_783.png,groundtruth,17_783.txt,MAC_Bench/Science/Cover/Science Translational Medicine/2_15.png,MAC_Bench/Science/Cover/Science Translational Medicine/2_15.png,clip,2_15.txt,MAC_Bench/Science/Cover/Science Translational Medicine/9_408.png,MAC_Bench/Science/Cover/Science Translational Medicine/9_408.png,vith,9_408.txt,train333ACS Sensors,2024_8,Which of the following options best describe the cover story?,"Rich surface oxygen vacancies play the role of active sites for adsorption of NO2 molecules, and the Schottky junctions effectively adjust the charge transfer behavior through the conduction tunnel in the sensing material. Furthermore, In2O3 nanoparticles almost fully cover the",A,MAC_Bench/ACS/Cover/ACS Sensors/2024_8.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/ACS Sensors/2016_11.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_11.png,vitg,2016_11.txt,MAC_Bench/ACS/Cover/ACS Sensors/2023_7.png,MAC_Bench/ACS/Cover/ACS Sensors/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Sensors/2019_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2019_4.png,clip,2019_4.txt,train334ACS Infectious Diseases,2024_3,Which of the following options best describe the cover story?,"Background image generated by Abdulmujeeb Onawole using DALL·E with the prompt “silhouette of an investigator with a deerstalker hat and a magnifying glass, surrounded by bacteria and floating pills”, with superimposed structures of a range of novel antibiotics that act on new bacterial targets.",C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2020_7.png,clip,2020_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,ave_3,2019_5.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_3.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_9.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_9.png,vitg,2018_9.txt,train335Nature Synthesis,3_12,Which of the following options best describe the cover story?,"MOFs made to order336The synthesis of isoreticular zeolite-like MOFs is achieved using a face-directed assembly strategy inspired by architecture techniques. The strategy combines a supermolecular building block approach with the use of various centring structure-directing agents.337See Barsukova et al.338Image: Aleksandr Sapianik. Cover design: Amie Fernandez",A,MAC_Bench/Nature/Cover/Nature Synthesis/3_12.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_12.png,groundtruth,3_12.txt,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/2_6.png,vitg,2_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/1_6.png,MAC_Bench/Nature/Cover/Nature Synthesis/1_6.png,clip,1_6.txt,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,MAC_Bench/Nature/Cover/Nature Synthesis/3_1.png,ave_1,3_1.txt,val339Industrial & Engineering Chemistry Research,2024_29,Which of the following options best describe the cover story?,A mathematical model has been developed based on boundary-forming points in a solid–solid–liquid ternary phase diagram for tie-line prediction.,A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_29.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_29.png,groundtruth,2024_29.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_2.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_2.png,clip,2022_2.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_17.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_17.png,vitg,2021_17.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_10.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_10.png,vith,2022_10.txt,val340NATURE REVIEWS MICROBIOLOGY,22_3,Which of the following options best describe the cover story?,"Tackling bacterial antimicrobial resistance, inspired by the Focus issue.341Cover design: Amie Fernandez",C,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/20_8.png,ave_2,20_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,clip,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_3.png,groundtruth,22_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_8.png,vith,19_8.txt,train342Trends in Microbiology,32_8,Which of the following options best describe the cover story?,"Nitrogen (N) is absolutely essential to life as we know it. Though343atmospherically abundant, N must first be converted, or “fixed,” prior to biological344uptake345and crop fertilizer manufacturing. Synthetic N-fixation, today responsible for half346of all fixed347N, comes with profound economic and environmental costs. Fortunately, an alternative,348ancient biological strategy—catalyzed by microbially hosted nitrogenase proteins—holds349enormous bioengineering potential for sustainable N-fixation. Yet, researchers have350been351unable to mimic this elegant biological solution and lack an understanding of environmental352drivers in its evolution, limiting predictions for how biological N-fixation will353respond to a354changing climate. In this special issue, Holly Rucker and Betül Kaçar review the complex355history of nitrogen fixation over billions of years of planetary history.356Image courtesy: Prof. Betül Kaçar, UW-Madison.",D,MAC_Bench/Cell/Cover/Trends in Microbiology/19_8.png,MAC_Bench/Cell/Cover/Trends in Microbiology/19_8.png,vitg,19_8.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/23_5.png,MAC_Bench/Cell/Cover/Trends in Microbiology/23_5.png,vith,23_5.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/21_1.png,MAC_Bench/Cell/Cover/Trends in Microbiology/21_1.png,clip,21_1.txt,MAC_Bench/Cell/Cover/Trends in Microbiology/32_8.png,MAC_Bench/Cell/Cover/Trends in Microbiology/32_8.png,groundtruth,32_8.txt,train357Accounts of Materials Research,2024_9,Which of the following options best describe the cover story?,"Sunscreens are used to protect the skin from ultraviolet radiation (UVR)-induced carcinogenic effects on mammalian skin. Many sunscreens harness the UVR absorbing properties of ZnO and TiO2, which results in a white film left on the skin. Factors contributing to white cast include particle size, polymeric dispersion, and surface treatment of the ZnO and TiO2 used in sunscreens. This Viewpoint provides a physicochemical framework for best practices in standardizing the white cast potential of sunscreen formulations with metal oxide UVR filters.",B,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_9.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2024_11.png,ave_2,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_7.png,MAC_Bench/ACS/Cover/Accounts of Materials Research/2022_7.png,ave_3,2022_7.txt,train358Nature Cities,1_5,Which of the following options best describe the cover story?,"Cooling from natural areas359Overheating of cities is an increasing problem. Cao et al. investigate how neighboring rural land cover can mitigate and absorb urban heat.360See Yang et al.361Image: Shijie Cao, Southeast University, China. Cover design: Lauren Heslop.",C,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,MAC_Bench/Nature/Cover/Nature Cities/1_11.png,vith,1_11.txt,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,MAC_Bench/Nature/Cover/Nature Cities/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,MAC_Bench/Nature/Cover/Nature Cities/1_5.png,groundtruth,1_5.txt,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,MAC_Bench/Nature/Cover/Nature Cities/1_2.png,vitg,1_2.txt,train362Trends in Immunology,45_3,Which of the following options best describe the cover story?,"Our special issue on ‘Neuroimmunology – II’ presents current research363in this discipline, highlighting the crosstalk between the immune and nervous systems364(central or peripheral). The micrograph on the cover shows an optical section through365a366dorsal root ganglion (green) taken from an MHC-II I–Abβ-eGFP reporter mouse at steady367state. The neurons (red) are stained with anti-β3-tubulin antibody (AF568) and the368nuclei369(blue) with DAPI. The image was acquired using a laser-scanning confocal microscope370at 20x magnification, and digitally upscaled using Topaz Gigapixel AI software. Image371credit: Pavel Hanc and Ulrich von Andrian.",A,MAC_Bench/Cell/Cover/Trends in Immunology/45_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_3.png,groundtruth,45_3.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_4.png,ave_1,36_4.txt,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/39_14.png,vitg,39_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,MAC_Bench/Cell/Cover/Trends in Immunology/36_3.png,clip,36_3.txt,test372Trends in Chemistry,6_4,Which of the following options best describe the cover story?,"Light emitting diodes (LEDs) have revolutionized display technology373in our daily devices by efficiently converting electrical energy into light, with374organic375LEDs (OLEDs) being the most ubiquitous. For chemists, the emitter molecules376themselves hold the most interest, with properties that can be readily fine-tuned377to378unlock a diverse range of vibrant colours. In their review, Fan, Yuan and co-workers379explore recent advances in narrow-bandwidth carbon-based emitters (CBEs) including380small molecules, polymers, and carbon dots, with a focus on the relationship between381molecular structure and optical properties. CBE-based LEDs could hold great potential382as an efficient and widely adopted display technology for next-generation wide-color-gamut383displays. Cover credit: GettyImages/Yuanyuan Yan",A,MAC_Bench/Cell/Cover/Trends in Chemistry/6_4.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_4.png,groundtruth,6_4.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_13.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_13.png,ave_3,6_13.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/4_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_5.png,vith,4_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,MAC_Bench/Cell/Cover/Trends in Chemistry/5_9.png,clip,5_9.txt,train384Nature Neuroscience,27_5,Which of the following options best describe the cover story?,"Special issue on glia385Communication between glial cells has a profound effect on the pathophysiology of Alzheimer’s disease. Huang et al. report that reactive astrocytes impose cell distancing in peri-plaque glial nets via the guidance receptor Plexin-B1, which affects microglial access and compaction of amyloid plaques. The cover art depicts a fishing net catching fish, which symbolizes glial nets surrounding amyloid deposits in Alzheimer’s disease.386See Huang et al.387Image: Lily Armstrong-Davies, Mount Sinai Health Systems. Cover design: Marina Spence.",A,MAC_Bench/Nature/Cover/Nature Neuroscience/27_5.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_5.png,groundtruth,27_5.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/7_6.png,MAC_Bench/Nature/Cover/Nature Neuroscience/7_6.png,vitg,7_6.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/24_10.png,MAC_Bench/Nature/Cover/Nature Neuroscience/24_10.png,vith,24_10.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/12_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/12_2.png,clip,12_2.txt,test388Trends in Parasitology,41_2,Which of the following options best describe the cover story?,"The cover is the official logo of the 32nd National Congress of Parasitology389(NCP), Pune. The conference logo is inspired by Warli folk art, a tribal art originating390from391the Sahyadri range in Maharashtra, India. The logo is the visual representation of392the393theme of the conference, the impact of parasitic infections and vectors on both humans394and animals, with a One Health emphasis, and the need to take a holistic approach395to eliminate the burden of parasitic infections. In this issue of Trends in Parasitology,396Purkayastha et al. highlight the proceedings from the conference, which brought together397eminent parasitologists from India and also Africa to present and discuss their exciting398research from the field. Image credit: originally designed by Sindhuri Upadrasta and399further developed and digitally rendered by D.V. Mamatharani.",A,MAC_Bench/Cell/Cover/Trends in Parasitology/41_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/41_2.png,groundtruth,41_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_12.png,clip,35_12.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,MAC_Bench/Cell/Cover/Trends in Parasitology/31_10.png,vith,31_10.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,MAC_Bench/Cell/Cover/Trends in Parasitology/38_8.png,vitg,38_8.txt,train400NATURE REVIEWS DRUG DISCOVERY,23_11,Which of the following options best describe the cover story?,"Extracellular targeted protein degradation, inspired by the Review on p126.401Cover design: S. Harris",A,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_11.png,groundtruth,23_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_1.png,clip,22_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_9.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/21_9.png,vith,21_9.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,vitg,20_6.txt,test402Nature Reviews Nephrology,20_8,Which of the following options best describe the cover story?,"Health outcomes associated with hydration status, inspired by the Review on p275.403Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_7.png,clip,19_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,vitg,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_12.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_12.png,vith,17_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_8.png,groundtruth,20_8.txt,train404NATURE REVIEWS GENETICS,25_3,Which of the following options best describe the cover story?,"Inspired by the Review on p698.405Cover design: Patrick Morgan",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_3.png,groundtruth,25_3.txt,train406Nature Reviews Nephrology,21_1,Which of the following options best describe the cover story?,"Targeting IgA nephropathy, inspired by the Review on p9407Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_4.png,vitg,18_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,clip,17_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_2.png,ave_1,17_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/21_1.png,groundtruth,21_1.txt,test408Nature Neuroscience,28_2,Which of the following options best describe the cover story?,"Tau in AD extracellular vesicles409Brain extracellular vesicles (EVs) are thought to have a role in the clearance and spread of tau pathology in Alzheimer’s disease. However, the pathological tau species that are associated with EVs and how they contribute to clearance is unclear. Fowler, Behr and colleagues used electron cryo-tomography (cryo-ET) to image EVs from the brains of individuals with Alzheimer’s disease, directly visualizing the unexpected membrane-tethering of short tau filaments within EVs. The cover image represents the release of EVs containing membrane-tethered tau filaments from a neuron by blending the cryo-ET data with Gustav Klimt’s symbolist style.410See Fowler and Behr et al.411Image: Shraddha Nayak, VisLab, MRC Laboratory of Molecular Biology. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Neuroscience/24_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/24_11.png,vith,24_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/17_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/17_9.png,vitg,17_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/14_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_9.png,clip,14_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/28_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/28_2.png,groundtruth,28_2.txt,test412The Journal of Physical Chemistry A,2025_6,Which of the following options best describe the cover story?,"This cover feature depicts the immobilization of a [Ru(bpy)2(nicotine)2](Cl)2 (Ru-nico) complex from the aqueous solution to a polymer film. The Ru-nico complex in aqueous solution and rigid media, such as poly(methyl-methacrylate) (PMMA) and polyacrylonitrile (PAN) polymer films, were subjected to ultrafast transient absorption and emission studies. The findings provide ligand dissociation dynamics of the Ru-nico complex as the nicotine ligand gradually detaches from the Ru ion in solution, whereas this dissociation is inhibited in polymer films. This restricted ligand dissociation in films results in an emissive and long-lived state of Ru-nico in comparison to a nonemissive and short-lived state in solution. Cover design by Mohini Semwal and Ratnadip De.",C,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_26.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_26.png,vitg,2024_26.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_12.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_12.png,vith,2024_12.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_5.png,clip,2024_5.txt,train413ACS Chemical Biology,2025_2,Which of the following options best describe the cover story?,"Fluorescently labeled neutrophils (green) migrate from the blood island toward a tissue lesion generated by irradiating a small area of the fish with light, causing the production of cytotoxic radicals via activation of a photolatent BAPO compound.",D,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_3.png,vitg,2024_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,vith,2015_4.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2021_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2021_2.png,clip,2021_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png,groundtruth,2025_2.txt,train414Developmental Cell,59_16,Which of the following options best describe the cover story?,"On the cover: The cover displays three adult Drosophila optic lobes, each stained for a specific class of distal medulla neurons (top, Dm4;415middle, Dm1; bottom, Dm11) using multicolor stochastic labeling (MultiColor FlpOut,416or MCFO). In the accompanying paper, the authors show that each of these neurons is417born from neural stem cells derived from a specific larval subdomain within a patterned418neuroepithelium. The size of each domain of origin determines the abundance of each419specific neuronal type. Therefore, spatial patterning not only contributes to cell420fate specification but also regulates the stoichiometry of each neural class. To learn421more about how spatial patterning regulates neuronal cell fate in Drosophila, see Malin et al. Image credit: Jennifer Malin.",B,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,vitg,58_24.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_16.png,MAC_Bench/Cell/Cover/Developmental Cell/59_16.png,groundtruth,59_16.txt,MAC_Bench/Cell/Cover/Developmental Cell/30_1.png,MAC_Bench/Cell/Cover/Developmental Cell/30_1.png,vith,30_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/52_2.png,MAC_Bench/Cell/Cover/Developmental Cell/52_2.png,clip,52_2.txt,train422Nature Reviews Endocrinology,20_4,Which of the following options best describe the cover story?,"The relationship between the gut microbiota and thyroid disorders, inspired by the Review on p511.423Cover design: Jennie Vallis",C,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_6.png,ave_2,20_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/19_8.png,clip,19_8.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/15_3.png,MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/15_3.png,ave_3,15_3.txt,train424Macromolecules,2024_12,Which of the following options best describe the cover story?,The combination of Suzuki-Catalyst-Transfer-Polymerization and preparative size-exclusion chromatography enables automated fractionation into a narrow-disperse polymer and true monodisperse oligomer batches using cost-effective low-pressure LC equipment!,D,MAC_Bench/ACS/Cover/Macromolecules/2018_3.png,MAC_Bench/ACS/Cover/Macromolecules/2018_3.png,vith,2018_3.txt,MAC_Bench/ACS/Cover/Macromolecules/2020_10.png,MAC_Bench/ACS/Cover/Macromolecules/2020_10.png,ave_0,2020_10.txt,MAC_Bench/ACS/Cover/Macromolecules/2013_4.png,MAC_Bench/ACS/Cover/Macromolecules/2013_4.png,clip,2013_4.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_12.png,MAC_Bench/ACS/Cover/Macromolecules/2024_12.png,groundtruth,2024_12.txt,train425Nature Reviews Materials,9_4,Which of the following options best describe the cover story?,"Developing vaccines for glioblastoma remains challenging owing to the immunosuppressive microenvironment of the tumour and the presence of the blood–brain barrier. Nanomaterials can be tailored to address the limitations of glioblastoma vaccination, potentially paving the way for important advancements. The cover illustrates these efforts through a brain outline superimposed on nanoparticles. See Hameedat F. et al.426Cover image: Flavia Cristina Moreira de Sousa. Cover design: David Johnston.",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_2.png,clip,8_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_11.png,vitg,9_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_1.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_1.png,vith,7_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_4.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_4.png,groundtruth,9_4.txt,train427Trends in Cognitive Sciences,28_9,Which of the following options best describe the cover story?,"Physical activity plays a significant role in various aspects of brain health428across the lifespan. However, the consequences of sedentary behavior (SB) are not429well understood. In this issue of Trends in Cognitive Sciences, Liye Zou and colleagues430summarize and discuss the evidence regarding SB's impact on brain health, including431its effects on cognitive performance, structural or functional brain measures, and432the433risk of dementia across different age groups. They critically evaluate different methods434for assessing SB and suggest new opportunities for using digital technology in these435assessments. The cover illustration features an anthropomorphic cartoon depicting436two437types of sedentary behavior (passive and active sedentary behaviors). Cover image438from Liye Zou.",D,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/17_4.png,clip,17_4.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_10.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/19_10.png,vitg,19_10.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/25_4.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/25_4.png,ave_1,25_4.txt,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_9.png,MAC_Bench/Cell/Cover/Trends in Cognitive Sciences/28_9.png,groundtruth,28_9.txt,train439Chemical & Biomedical ImagingOpen Access,2025_2,Which of the following options best describe the cover story?,"This cover art represents the development of hyperspectral 3D stimulated Raman scattering microscopy (hyper-3D SRS) for studying lipid droplet (LD) dynamics during early embryogenesis. The illustration also highlights the spatial and chemical diversity of LDs within individual embryonic cells, revealing dynamic relationships between LD size and unsaturation levels as embryos develop. Sub-micrometer resolution and 3D optical sectioning capabilities of the hyper-3D SRS method uncover metabolic heterogeneity, showing its potential for clinical applications in the future.",B,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,ave_3,2023_6.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_3.png,clip,2023_3.txt,train440ACS Sensors,2024_5,Which of the following options best describe the cover story?,"Plasmonic hydrogen sensors are enhanced by using algorithms of phase space reconstruction and convolutional neural networks, achieving high accuracies, and significantly improving response speed, sensitivity, and the limit of detection. This work introduces safe, nonelectronic remote sensing, achieving 0.98 accuracy, with implications for advancing spectrum-based sensors.",D,MAC_Bench/ACS/Cover/ACS Sensors/2017_1.png,MAC_Bench/ACS/Cover/ACS Sensors/2017_1.png,clip,2017_1.txt,MAC_Bench/ACS/Cover/ACS Sensors/2023_2.png,MAC_Bench/ACS/Cover/ACS Sensors/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Sensors/2020_9.png,MAC_Bench/ACS/Cover/ACS Sensors/2020_9.png,vith,2020_9.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_5.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_5.png,groundtruth,2024_5.txt,val441Nature Reviews Electrical Engineering,2_1,Which of the following options best describe the cover story?,"High-resolution satellite sensors and artificial intelligence enable detailed tree monitoring at national and continental levels. The illustration depicts the results of the image processing of the data collected through tree mapping. See Brandt et al.442Image: Danish Agency for Data Supply and Infrastructure. Cover design: Sam Whitham.",A,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/2_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/2_1.png,groundtruth,2_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_3.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_3.png,ave_1,1_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_5.png,clip,1_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,vitg,1_9.txt,test443Nature Reviews Rheumatology,20_6,Which of the following options best describe the cover story?,"Inspired by the Review on p399.444Cover design: Steven Hall",D,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_6.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_6.png,groundtruth,20_6.txt,train445Caner Cell,42_10,Which of the following options best describe the cover story?,"On the cover: Du et al. propose a staging model for EBV-related nasopharyngeal carcinoma (NPC) based on a446large multicenter cohort in China, demonstrating its superiority over the currently447used AJCC staging system. The cover image features traditional Chinese embroidery448art. The embroidered Great Wall symbolizes the resolve to conquer NPC, while the nine449beacon towers, arranged from afar to close by, represent the continuous evolution450and improvement of each edition of the staging system, from the first to the ninth451edition of AJCC Stage. The presence of pines and cranes symbolizes the safeguarding452of health. Bathed in sunlight, the emblematic representation encapsulates the journey453toward precision medicine and radiates a message of optimism for the future of NPC454treatment. Image credit: Jun Ma.",B,MAC_Bench/Cell/Cover/Caner Cell/35_5.png,MAC_Bench/Cell/Cover/Caner Cell/35_5.png,clip,35_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_10.png,MAC_Bench/Cell/Cover/Caner Cell/42_10.png,groundtruth,42_10.txt,MAC_Bench/Cell/Cover/Caner Cell/22_1.png,MAC_Bench/Cell/Cover/Caner Cell/22_1.png,ave_2,22_1.txt,MAC_Bench/Cell/Cover/Caner Cell/29_1.png,MAC_Bench/Cell/Cover/Caner Cell/29_1.png,vitg,29_1.txt,test455ACS Catalysis,2024_12,Which of the following options best describe the cover story?,"A mild photochemical etching strategy was designed to induce nitrogen vacancies at the center of heptazine rings over g-C3N4 holey nanosheets, which enhance CO2 photoreduction via delocalized π electron clouds with tunable electronic structures and mid-gap states.",C,MAC_Bench/ACS/Cover/ACS Catalysis/2023_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_11.png,clip,2023_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2020_14.png,MAC_Bench/ACS/Cover/ACS Catalysis/2020_14.png,vitg,2020_14.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_12.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2011_3.png,MAC_Bench/ACS/Cover/ACS Catalysis/2011_3.png,vith,2011_3.txt,train456Trends in Chemistry,6_5,Which of the following options best describe the cover story?,"Whilst many often look to past giants to find that spark of inspiration,457there is something exciting in looking to the future. For our two-part fifth anniversary458special issue, Trends in Chemistry is amplifying rising stars and emerging leaders459in460chemistry today. Our cover for Part II continues on from Part I, highlighting some461of the462milestones and many paths taken on the 'great career race' for early-career scientists463today. Each running at their own pace, the authors in this special issue are all aiming464to innovate with an impact, solve real-world problems and become inspiring leaders465themselves. Artwork credit: Phillip Krzeminski",C,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,ave_2,6_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,clip,6_7.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,groundtruth,6_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,vith,6_6.txt,train466Matter,7_1,Which of the following options best describe the cover story?,"On the cover: The image presents an optimization landscape, with each local peak representing467a unique microstructure configuration. This visual concept aligns with Kench et al.'s recent paper, published in this issue, which outlines the application of generative468AI in mapping processing parameters to electrode microstructures, ultimately enhancing469cell performance. The landscape is depicted at sunrise, symbolizing the dawning of470a new era in materials design. Image courtesy of the authors.",C,MAC_Bench/Cell/Cover/Matter/2_6.png,MAC_Bench/Cell/Cover/Matter/2_6.png,vitg,2_6.txt,MAC_Bench/Cell/Cover/Matter/4_3.png,MAC_Bench/Cell/Cover/Matter/4_3.png,clip,4_3.txt,MAC_Bench/Cell/Cover/Matter/7_1.png,MAC_Bench/Cell/Cover/Matter/7_1.png,groundtruth,7_1.txt,MAC_Bench/Cell/Cover/Matter/2_2.png,MAC_Bench/Cell/Cover/Matter/2_2.png,ave_2,2_2.txt,train471Nature Ecology & Evolution,8_6,Which of the following options best describe the cover story?,"Name-calling472Desert Rose — the large female African elephant (Loxodonta africana) in the picture — produces a distress call that alerts her calves to danger, in Samburu Shaba National Reserve in northern Kenya. A study by Pardo et al. shows that individuals address conspecifics with name-like calls that do not rely on imitation of the receiver.473See Pardo et al.474Image: George Wittemyer. Cover Design: Allen Beattie.",D,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_8.png,vitg,2_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_1.png,clip,8_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_12.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_12.png,vith,8_12.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_6.png,groundtruth,8_6.txt,train475ACS Sustainable Chemistry & Engineering,2025_5,Which of the following options best describe the cover story?,"Ag-gCN nanocomposite catalysts were developed as copper-free alternatives for heterogeneous photocatalytic azide–alkyne cycloaddition reactions. The developed protocol shows a significant advancement in green chemistry, offering a sustainable, versatile, and efficient alternative for a broad range of substrates.",B,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_16.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_16.png,clip,2020_16.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_5.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_5.png,groundtruth,2025_5.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2019_17.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2019_17.png,vitg,2019_17.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_10.png,ave_1,2021_10.txt,train476NATURE REVIEWS DRUG DISCOVERY,23_10,Which of the following options best describe the cover story?,"Targeting hypoxia-inducible factors, inspired by the Review on p175.477Cover design: S. Harris",D,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,vitg,23_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png,clip,23_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/20_6.png,vith,20_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_10.png,groundtruth,23_10.txt,test478Nature Cancer,5_7,Which of the following options best describe the cover story?,"Targeting tumor vascularization479De Palma and Hanahan outline the latest advances in understanding tumor angiogenesis and discuss therapeutic opportunities for targeting tumor vascularization.480See De Palma and Hanahan481Image: Mohammed Elamine ALIOUI / Alamy Stock Photo. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Cancer/3_6.png,MAC_Bench/Nature/Cover/Nature Cancer/3_6.png,clip,3_6.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_4.png,MAC_Bench/Nature/Cover/Nature Cancer/4_4.png,vitg,4_4.txt,MAC_Bench/Nature/Cover/Nature Cancer/5_7.png,MAC_Bench/Nature/Cover/Nature Cancer/5_7.png,groundtruth,5_7.txt,MAC_Bench/Nature/Cover/Nature Cancer/4_3.png,MAC_Bench/Nature/Cover/Nature Cancer/4_3.png,ave_2,4_3.txt,train482ACS Applied Optical Materials,2024_6,Which of the following options best describe the cover story?,"In this invited paper, the authors developed new quantum-dot color conversion layers for micro-LED devices which could be applied to next-generation augmented reality displays",A,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,clip,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_12.png,vitg,2023_12.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_9.png,vith,2023_9.txt,val483The Journal of Organic Chemistry,2025_6,Which of the following options best describe the cover story?,"In an industrial setting, toluene oxidation products such as benzoic acid, benzaldehyde, and benzoate esters are crucial fine chemicals. Chemists are dedicated to preparing high-value chemical materials through green and simple oxidation technologies. This cover illustrates an aryl-halides-initiated photocatalytic strategy for the green and selective oxidation of toluene.",B,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_19.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2017_19.png,vith,2017_19.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_6.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2025_6.png,groundtruth,2025_6.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_21.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_21.png,vitg,2021_21.txt,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_18.png,MAC_Bench/ACS/Cover/The Journal of Organic Chemistry/2021_18.png,clip,2021_18.txt,val484Accounts of Chemical Research,2024_12,Which of the following options best describe the cover story?,Membrane-spanning α-helical peptide pores for single-molecule sensing.,B,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2016_3.png,vith,2016_3.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_12.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_12.png,groundtruth,2024_12.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_6.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2012_6.png,clip,2012_6.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2015_3.png,vitg,2015_3.txt,val485Industrial & Engineering Chemistry Research,2024_22,Which of the following options best describe the cover story?,"a) Summarized study methodology. b) Schematics related to the motivation of this study, which is controllable intelligent microfluidic nanoparticle synthesis. c) Overview of the research methods:",A,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_22.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_30.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_30.png,vith,2020_30.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_48.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_48.png,vitg,2022_48.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_9.png,clip,2020_9.txt,train486Nature Nanotechnology,19_6,Which of the following options best describe the cover story?,"Switchable non-volatile topological devices487The cover image illustrates the ferroelectric hysteresis loop in doubly aligned magic-angle bilayer graphene. Applying an electric field to this heterostructure injects electrons into the ferroelectric graphene system non-volatilely, enabling quasi-continuous switchable ferroelectric states. This ferroelectricity coexists with the Chern insulator effect, enabling the selective switching of topologically protected quantum edge states, which can support noise-immune neuromorphic computing applications.488See Cheng et al.489Image: Chaoyang Zhao, independent artist; and Moyu Chen, Nanjing University. Cover design: Debbie Maizels.",D,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/7_11.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/7_11.png,vitg,7_11.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/6_7.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/6_7.png,ave_1,6_7.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_6.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_6.png,groundtruth,19_6.txt,train490Cell Metabolism,36_10,Which of the following options best describe the cover story?,"On the cover: Stress has a profound impact on gut disorders. In this issue of Cell Metabolism, Wei et al. reveal that psychological stress enriches gut microbial metabolite indole-3-acetate,491which disrupts intestinal stem cell differentiation and triggers epithelial injury.492The depiction of rolling clouds and stirring stars, inspired by Van Gogh’s masterpiece493The Starry Night, represents restless emotions in a person with depression. The broken ground and494castle along the winding river illustrate injured intestinal epithelia. The involvement495of microbes and the metabolite is represented as ants on the broken door. Cover art496by Xiao Zheng and Haiping Hao.",B,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_1.png,ave_2,37_1.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png,groundtruth,36_10.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_7.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_7.png,clip,36_7.txt,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,MAC_Bench/Cell/Cover/Cell Metabolism/37_2.png,vitg,37_2.txt,val497Nature Photonics,18_10,Which of the following options best describe the cover story?,"Quantum skyrmions498Two-photon entangled states with a non-trivial topology are used to form quantum skyrmions that exhibit topological invariance.499See Ornelas et al.500Image: Pedro Ornelas, University of the Witwatersrand. Cover Design: Bethany Vukomanovic",A,MAC_Bench/Nature/Cover/Nature Photonics/18_10.png,MAC_Bench/Nature/Cover/Nature Photonics/18_10.png,groundtruth,18_10.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_12.png,MAC_Bench/Nature/Cover/Nature Photonics/6_12.png,vith,6_12.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,clip,18_4.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,vitg,6_11.txt,val501NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY,21_4,Which of the following options best describe the cover story?,"Designing clinical trials for alcohol use, inspired by the Consensus Statement on p626.502Cover design: Laura Marshall",D,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_6.png,ave_2,21_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_11.png,clip,20_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_11.png,ave_3,21_11.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_4.png,groundtruth,21_4.txt,test503Nature Reviews Physics,6_1,Which of the following options best describe the cover story?,"The cover of this issue illustrates the use of diamond sensors for many-body physics. See de Leon.504Image: Jared Rovny. Cover design: Susanne Harris.",A,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_11.png,vith,4_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_10.png,MAC_Bench/Nature/Cover/Nature Reviews Physics/4_10.png,vitg,4_10.txt,train505Trends in Pharmacological Sciences,45_2,Which of the following options best describe the cover story?,"Development of protective immune responses relies on a balance506between proinflammatory CD4 T helper (Th) cell populations such as Th17 cells and507regulatory CD4 T cells (Tregs) that keep immune activation in check. In this issue,508Kaul509and Schwartzberg discuss the role of interleukin-2–inducible T cell kinase (Itk),510which511controls the activation of phospholipase C gamma, Ca2+ influx and the activity of the512NFAT transcription factor, in regulating the balance between Th17 and Tregs. They513also explore the potential of inhibiting Itk as a therapeutic strategy for autoimmune514diseases. Dark pink/orange cells are Th17 cells with greater Itk activity and Ca2+ flux.515Light pink cell represents a Treg cell with decreased Itk activity and Ca2+ flux. Cover516art designed by Alexander Stewart, NIAID using Maxon Cinema4D Software.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/43_5.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/43_5.png,vitg,43_5.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_9.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_9.png,ave_2,42_9.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/45_2.png,groundtruth,45_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/34_8.png,clip,34_8.txt,train517NATURE REVIEWS MICROBIOLOGY,22_6,Which of the following options best describe the cover story?,"Targeting SARS-CoV-2, inspired by the Review on p391.518Cover design: Philip Patenall",B,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_10.png,clip,21_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_6.png,groundtruth,22_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/21_1.png,vitg,21_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/19_6.png,vith,19_6.txt,train519Organic Letters,2025_8,Which of the following options best describe the cover story?,"This cover art illustrates that when two coupling partners, ferrocene-p-tosylamides and allenes, were treated in the presence of Rh-catalyst, it led to the formation of two diastereodivergent [4+3] annulated ferrocene-p-tosylamides at two different temperatures, i.e., at room temperature (represented as moon in cover art) and at 60 °C (represented as sun in cover art). At room temperature, Rh-catalyzed [4+3] annulation selectively offered kinetically controlled diastereomer (>20:1 dr), whereas at 60 °C, a thermodynamically controlled diastereomer was obtained exclusively with >20:1 dr. This cover art has been designed by Sangit Kumar, Raviraj Ananda Thorat, and Raushan Kumar Jha. View the article.",C,MAC_Bench/ACS/Cover/Organic Letters/2023_5.png,MAC_Bench/ACS/Cover/Organic Letters/2023_5.png,vith,2023_5.txt,MAC_Bench/ACS/Cover/Organic Letters/2023_7.png,MAC_Bench/ACS/Cover/Organic Letters/2023_7.png,vitg,2023_7.txt,MAC_Bench/ACS/Cover/Organic Letters/2025_8.png,MAC_Bench/ACS/Cover/Organic Letters/2025_8.png,groundtruth,2025_8.txt,MAC_Bench/ACS/Cover/Organic Letters/2022_43.png,MAC_Bench/ACS/Cover/Organic Letters/2022_43.png,clip,2022_43.txt,val520Lab Animal,54_2,Which of the following options best describe the cover story?,"Dietary effects across mouse life stages521Differences in standard chow diets can influence mouse model phenotypes and impact experimental reproducibility. In a new Article, Knuth et al. measured the phenotypic effects of exposing mice to commonly used standard chows during different life stages. Their findings demonstrate that the timing of diet exposure can also affect phenotypic outcomes.522See Knuth et al.523Cover image: Marina Spence. Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Lab Animal/53_2.png,MAC_Bench/Nature/Cover/Lab Animal/53_2.png,clip,53_2.txt,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,MAC_Bench/Nature/Cover/Lab Animal/52_2.png,vitg,52_2.txt,MAC_Bench/Nature/Cover/Lab Animal/53_7.png,MAC_Bench/Nature/Cover/Lab Animal/53_7.png,ave_3,53_7.txt,MAC_Bench/Nature/Cover/Lab Animal/54_2.png,MAC_Bench/Nature/Cover/Lab Animal/54_2.png,groundtruth,54_2.txt,train524Science Signaling,2007_411,Which of the following options best describe the cover story?,"COVER This week features a  Perspective on neurotrophic factors as a possible approach to the therapy of Parkinson's disease and other neurodegenerative disorders. The image depicts a brain. [Image: Christopher Bickel, AAAS]",D,MAC_Bench/Science/Cover/Science Signaling/2_79.png,MAC_Bench/Science/Cover/Science Signaling/2_79.png,vitg,2_79.txt,MAC_Bench/Science/Cover/Science Signaling/7_311.png,MAC_Bench/Science/Cover/Science Signaling/7_311.png,vith,7_311.txt,MAC_Bench/Science/Cover/Science Signaling/17_841.png,MAC_Bench/Science/Cover/Science Signaling/17_841.png,clip,17_841.txt,MAC_Bench/Science/Cover/Science Signaling/2007_411.png,MAC_Bench/Science/Cover/Science Signaling/2007_411.png,groundtruth,2007_411.txt,train525iScience,27_9,Which of the following options best describe the cover story?,"On the cover: People's vision for a future electricity system is decentralized, willing526to accept trade-offs, as shown in Mey et al. The picture captures this future vision with a person walking toward a small-scale527wind farm (six turbines) in the vicinity of several villages and settlements in central528Germany. Image credit: Lech Aleksandrowicz.",D,MAC_Bench/Cell/Cover/iScience/25_1.png,MAC_Bench/Cell/Cover/iScience/25_1.png,ave_3,25_1.txt,MAC_Bench/Cell/Cover/iScience/28_2.png,MAC_Bench/Cell/Cover/iScience/28_2.png,ave_2,28_2.txt,MAC_Bench/Cell/Cover/iScience/28_3.png,MAC_Bench/Cell/Cover/iScience/28_3.png,clip,28_3.txt,MAC_Bench/Cell/Cover/iScience/27_9.png,MAC_Bench/Cell/Cover/iScience/27_9.png,groundtruth,27_9.txt,train529Trends in Immunology,45_14,Which of the following options best describe the cover story?,"The image is an illustration of Louis Pasteur in his laboratory. A few530articles in this issue address vaccinology and the importance of better understanding531host immune responses to design better preventive or therapeutic vaccines. For532instance, Ellebedy and Wu discuss the potential of targeting neuraminidase to533generate broadly protective influenza virus vaccines; Guo and colleagues review534current information on mRNA vaccines in cancer nanomedicine and immunotherapy;535also, Levy, Palma et al. delve into the realm of modeling human immune responses to536vaccination in vitro. Image credit: GettyImages.",C,MAC_Bench/Cell/Cover/Trends in Immunology/44_7.png,MAC_Bench/Cell/Cover/Trends in Immunology/44_7.png,clip,44_7.txt,MAC_Bench/Cell/Cover/Trends in Immunology/44_6.png,MAC_Bench/Cell/Cover/Trends in Immunology/44_6.png,ave_2,44_6.txt,MAC_Bench/Cell/Cover/Trends in Immunology/45_14.png,MAC_Bench/Cell/Cover/Trends in Immunology/45_14.png,groundtruth,45_14.txt,MAC_Bench/Cell/Cover/Trends in Immunology/46_1.png,MAC_Bench/Cell/Cover/Trends in Immunology/46_1.png,ave_3,46_1.txt,train537ACS Polymers Au,2024_3,Which of the following options best describe the cover story?,"Schematic representation of large size polar aggregates formed via hydrogen bonding between phosphate-terminated cis-1,4-polyisoprene chains in natural rubber (NR). The presence of multiple large size phosphate aggregates suggests a potential mechanism contributing to the superior comprehensive properties such as strain-induced crystallization observed in NR compared to synthetic polyisoprene.",D,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_6.png,ave_2,2023_6.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2023_4.png,vitg,2023_4.txt,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Polymers Au/2024_3.png,groundtruth,2024_3.txt,test538NATURE REVIEWS CANCER,25_2,Which of the following options best describe the cover story?,"Transitioning through mountain terrain, inspired by the Review on p7.539Cover design: Lara Crow",D,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/13_3.png,ave_3,13_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_1.png,ave_2,25_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_8.png,clip,23_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/25_2.png,groundtruth,25_2.txt,test540ACS Applied Materials & Interfaces,2025_4,Which of the following options best describe the cover story?,"One novel nanoplatform integrating fluorescence/photothermal/magnetic resonance multimodal imaging with chemodynamic/photothermal/gas synergistic therapy has been successfully prepared, which exhibits an excellent colon cancer targeting and inhibiting effect.",B,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_32.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_32.png,vitg,2016_32.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_4.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_42.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_42.png,ave_2,2016_42.txt,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_41.png,MAC_Bench/ACS/Cover/ACS Applied Materials & Interfaces/2016_41.png,clip,2016_41.txt,val541Cell Genomics,4_8,Which of the following options best describe the cover story?,"On the cover: As we age—particularly with Alzheimer’s—various processes centered on542our DNA become gradually “broken.” Collectively, these changes, reviewed by Gouveia Roque et al. in this issue of Cell Genomics, act as drivers of disease progression and cognitive decline. The cover highlights543this relationship, drawing inspiration from the genetic mosaicism now known to characterize544the Alzheimer’s brain. Image credit: Cláudio Gouveia Roque.",A,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,MAC_Bench/Cell/Cover/Cell Genomics/4_8.png,groundtruth,4_8.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,MAC_Bench/Cell/Cover/Cell Genomics/3_1.png,clip,3_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,vitg,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,MAC_Bench/Cell/Cover/Cell Genomics/2_1.png,ave_1,2_1.txt,train545Accounts of Chemical Research,2025_2,Which of the following options best describe the cover story?,Elements of this cover art were generated with Adobe Firefly generative AI and blended with Adobe Photoshop.,A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_2.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_15.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2022_15.png,vith,2022_15.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_11.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_11.png,vitg,2024_11.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_9.png,clip,2024_9.txt,val546ACS Infectious Diseases,2024_2,Which of the following options best describe the cover story?,HBV persistence in the host cells is mediated by several regulatory proteins. E3 ubiquitin ligase UBR7 plays a crucial role in suppressing the IFN-β signaling and promotes viral proliferation leading to HBV-induced HCC.,C,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2015_10.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2015_10.png,clip,2015_10.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_6.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_6.png,ave_0,2018_6.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png,vitg,2024_10.txt,train547Industrial & Engineering Chemistry Research,2024_48,Which of the following options best describe the cover story?,"The hydroisomerization of n-heptane on Pt/WO3/ZrO2 catalyst takes place on Lewis and Brönsted acid sites, which synergistically convert the intermediate carbocations into branched C7-paraffins, thus contributing to the production of high-octane gasoline. Single-event kinetic modeling of the isomerization and cracking reactions has been used to elucidate the reaction mechanism.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_44.png,vitg,2022_44.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_48.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_48.png,groundtruth,2024_48.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2023_9.png,clip,2023_9.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_19.png,vith,2022_19.txt,train548ACS ES&T Engineering,2024_6,Which of the following options best describe the cover story?,"Laser-induced graphene-based electroconductive membranes (ECMs) have the potential for electro-cleaning of the fouled membranes. Non-oxidative electro-cleaning effectively prolongs the ECM lifespan by avoiding damage, while catalytic oxidative cleaning offers superior flux recovery for severely fouled membranes, highlighting innovative strategies for enhancing ECM performance in membrane technology.",A,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_6.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_1.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2024_1.png,vitg,2024_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_3.png,MAC_Bench/ACS/Cover/ACS ES&T Engineering/2022_3.png,vith,2022_3.txt,train549Analytical Chemistry,2025_4,Which of the following options best describe the cover story?,"–ion mobility spectrometry (GC-IMS) as a point-of-need alternative for volatilomics. Furthermore, the capabilities and versatility of machine learning (chemometric) techniques used in the framework of GC-IMS analysis are also discussed. Art by the team of INMYWORK Studio.",C,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_23.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2020_23.png,clip,2020_23.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2022_33.png,vith,2022_33.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_10.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2019_10.png,vitg,2019_10.txt,train550NATURE REVIEWS MOLECULAR CELL BIOLOGY,25_7,Which of the following options best describe the cover story?,"‘Iron-dependent cell death’, inspired by the Review on p424551Cover design: Vicky Summersby",C,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_4.png,clip,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_10.png,vith,23_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/25_7.png,groundtruth,25_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/15_6.png,vitg,15_6.txt,train552Nature Reviews Materials,9_10,Which of the following options best describe the cover story?,"Microscale robots' unique active motion enables their precise navigation in different aqueous biological or environmental media. The image shows an artist’s impression of microrobots using photocatalysis to degrade chemical and biological warfare agents for environmental remediation. See Chen C. et al553Cover image: David Johnston.",A,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_10.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_10.png,groundtruth,9_10.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png,vitg,9_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_2.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/5_2.png,ave_2,5_2.txt,train554Journal of Medicinal Chemistry,2024_2,Which of the following options best describe the cover story?,"This cover depicts a promising approach in drug discovery for the treatment of Alzheimer’s disease. Via phenotypic discovery of triple-target combinations with synergistic effects on microglia, an in silico restricted fragment docking strategy was developed to achieve “three birds with one stone”. The optimal ligand showed in vitro and in vivo efficacy by precisely modulating targets of interest. View the article.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_14.png,ave_2,2020_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2012_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2012_4.png,clip,2012_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_11.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_11.png,ave_1,2021_11.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_2.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_2.png,groundtruth,2024_2.txt,test555Nature Plants,10_1,Which of the following options best describe the cover story?,"Rewiring for life on land556To colonize the land, plants had to evolve ways to obtain nutrients from barren terrains. The nutrient-response networks of liverworts, such as Marchantia polymorpha, show how this was achieved through extensive reorganization of the core components they share with distantly related, water-living algae557See Dong, Y. et al.558Image: Daisuke Urano, Temasek Life Sciences Laboratory. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/Nature Plants/7_7.png,MAC_Bench/Nature/Cover/Nature Plants/7_7.png,clip,7_7.txt,MAC_Bench/Nature/Cover/Nature Plants/10_1.png,MAC_Bench/Nature/Cover/Nature Plants/10_1.png,groundtruth,10_1.txt,MAC_Bench/Nature/Cover/Nature Plants/9_1.png,MAC_Bench/Nature/Cover/Nature Plants/9_1.png,ave_2,9_1.txt,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,MAC_Bench/Nature/Cover/Nature Plants/4_6.png,ave_3,4_6.txt,train559One Earth,7_2,Which of the following options best describe the cover story?,"On the cover: The Brazilian Amazon Açaí berry, which contains antioxidant, hypolipidemic,560and anti-inflammatory properties, has boosted local economies within the Brazilian561Amazon. This image captures baskets filled with Açaí placed at Feira do Açaí (Açaí562Market), a public trading open-air market specifically for Açaí, on the Ver-o-Peso563in Belé, the capital of Pará state in the Amazon region in the north of Brazil. Getty,564Paulo Amorim.",A,MAC_Bench/Cell/Cover/One Earth/7_2.png,MAC_Bench/Cell/Cover/One Earth/7_2.png,groundtruth,7_2.txt,MAC_Bench/Cell/Cover/One Earth/6_8.png,MAC_Bench/Cell/Cover/One Earth/6_8.png,vitg,6_8.txt,MAC_Bench/Cell/Cover/One Earth/5_8.png,MAC_Bench/Cell/Cover/One Earth/5_8.png,clip,5_8.txt,MAC_Bench/Cell/Cover/One Earth/7_3.png,MAC_Bench/Cell/Cover/One Earth/7_3.png,ave_3,7_3.txt,train565Nature Ecology & Evolution,8_7,Which of the following options best describe the cover story?,"Urban mutations566Ring-billed Gull in Hamilton Harbour, Hamilton, Canada, with steel-plant smokestacks in the background. The smokestacks emit polycyclic hydrocarbons that have been shown to induce heritable mutations in herring gulls and mammals. A Perspective by Johnson et al. highlights how such mutations may be important for the ecology, evolution and health of diverse organisms.567See Johnson et al.568Image: Marc Johnson. Cover Design: Allen Beattie.",A,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_7.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_7.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_7.png,vith,2_7.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_9.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_9.png,clip,8_9.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_3.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_3.png,vitg,1_3.txt,test569Current Biology,34_17,Which of the following options best describe the cover story?,"On the cover: Corynactis californica is a corallimorph—which are the closest living relatives of stony corals—that lives570in the cold waters of the Northeast Pacific. In this issue, Trznadel et al. show that Corynactis and many other anthozoans from this cold environment harbor571corallicolids, apicomplexan parasites that commonly infect corals and were previously572thought to be restricted to tropical coral reef ecosystems. Image by Patrick Keeling.",D,MAC_Bench/Cell/Cover/Current Biology/27_17.png,MAC_Bench/Cell/Cover/Current Biology/27_17.png,ave_3,27_17.txt,MAC_Bench/Cell/Cover/Current Biology/23_11.png,MAC_Bench/Cell/Cover/Current Biology/23_11.png,clip,23_11.txt,MAC_Bench/Cell/Cover/Current Biology/23_7.png,MAC_Bench/Cell/Cover/Current Biology/23_7.png,ave_2,23_7.txt,MAC_Bench/Cell/Cover/Current Biology/34_17.png,MAC_Bench/Cell/Cover/Current Biology/34_17.png,groundtruth,34_17.txt,train573Trends in Biotechnology,42_4,Which of the following options best describe the cover story?,"Even though cultivated meat has been approved for sale and consumption574in multiple countries, its consumer appeal remains low, in part because of poor perceptions575of palatability. In pages 1112–1127 of this issue, Lambert and colleagues discuss576scientific577and engineering approaches to improving palatability in cultivated meat. The cover578image579was inspired by the bright watercolor qualities of vintage food advertisements, displaying580the delicious appeal and palatability of this cell/ham hybrid which any housewife581would want582to serve on her table. Cover image from Marissa Sirois, VI4 Artist-in-Residence Program.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_4.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_4.png,groundtruth,42_4.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_9.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/38_9.png,clip,38_9.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/40_10.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/40_10.png,vitg,40_10.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/41_6.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/41_6.png,vith,41_6.txt,train583Cell Stem Cell,32_1,Which of the following options best describe the cover story?,"On the cover: In this issue, Voit et al. report on the development of a unified gene therapy approach applicable to all patients584with the inherited bone marrow failure syndrome Diamond-Blackfan anemia (DBA). Mutations585in one of more than 30 genes cause erythroid maturation arrest in DBA, but regulated586lentiviral expression of the transcription factor GATA1 exclusively in developing587erythroid progenitors overcomes the erythroid maturation arrest irrespective of causative588gene mutation and improves erythroid output in DBA. The cover image depicts a blood589factory, representative of the bone marrow, with hematopoietic stem cells undergoing590differentiation. Some developing cells commit to erythroid differentiation but are591blocked by a pile of rubble with diamonds and black fans, representing DBA. To overcome592this, factory workers labeled GATA1 are running to help carry the progenitors around593the obstacle, leading to increased production of mature red blood cells. Cover illustrated594by DrawImpacts.",A,MAC_Bench/Cell/Cover/Cell Stem Cell/32_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/32_1.png,groundtruth,32_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/23_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/23_2.png,clip,23_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/6_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_1.png,vitg,6_1.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,MAC_Bench/Cell/Cover/Cell Stem Cell/9_1.png,vith,9_1.txt,test595Nature Structural & Molecular Biology,31_6,Which of the following options best describe the cover story?,"The scoop on γTuRC596Studies by Aher et al. and Dendooven et al. reveal the structure of the γ-tubulin ring complex (γTuRC) and show that it acts as a perfect template for 13-protofilament microtubules during nucleation.597See Aher et al. and Dendooven et al.598Image credit: Olivia Grigorita/500px/Getty images. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_6.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_6.png,groundtruth,31_6.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_1.png,vith,26_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,clip,30_3.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/28_8.png,vitg,28_8.txt,test599Cell Genomics,5_1,Which of the following options best describe the cover story?,"On the cover: The cover illustrates the dynamic process of bacterial immune adaptation600against bacterial viruses (phages) in different environments via a key mechanism of601acquiring CRISPR-Cas spacers, a study conducted by An-Ni Zhang et al. in this issue of Cell Genomics. The green section shows the rapid immunity update observed in controlled experimental602conditions, occurring on a timescale of hours. In contrast, the red section demonstrates603a much slower rate of CRISPR-Cas spacer acquisition in natural environments, such604as the human gut microbiome, where updates occur over several years. The findings605of this study further unravel the underlying mechanisms driving the continual arms606race between hosts and parasites in various organisms. Artist credit: An-Ni Zhang.",B,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,MAC_Bench/Cell/Cover/Cell Genomics/4_12.png,ave_2,4_12.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,MAC_Bench/Cell/Cover/Cell Genomics/5_1.png,groundtruth,5_1.txt,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,MAC_Bench/Cell/Cover/Cell Genomics/5_2.png,clip,5_2.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,MAC_Bench/Cell/Cover/Cell Genomics/4_7.png,ave_3,4_7.txt,train607Structure,32_4,Which of the following options best describe the cover story?,"On the cover: Acid-switched antibodies with fully natural human domains can be developed608using light-chain shuffling and phage display technology. In Tulika et al., monoclonal antibodies with such pH-dependent antigen-binding properties were discovered609against snake venom toxins, which they bind at a neutral pH and release at a low pH.610Image credits: Esperanza Rivera de Torre, Monica Lisa Ines Fernandez Quintero, and611Andreas Hougaard Laustsen.",C,MAC_Bench/Cell/Cover/Structure/24_10.png,MAC_Bench/Cell/Cover/Structure/24_10.png,vith,24_10.txt,MAC_Bench/Cell/Cover/Structure/33_2.png,MAC_Bench/Cell/Cover/Structure/33_2.png,clip,33_2.txt,MAC_Bench/Cell/Cover/Structure/32_4.png,MAC_Bench/Cell/Cover/Structure/32_4.png,groundtruth,32_4.txt,MAC_Bench/Cell/Cover/Structure/24_6.png,MAC_Bench/Cell/Cover/Structure/24_6.png,vitg,24_6.txt,train612Nature Microbiology,9_11,Which of the following options best describe the cover story?,"Visualizing Tc toxin release613This image shows type 10 secretion system (T10SS)-mediated Tc toxin release by Yersinia entomophaga, as captured by cryo-electron tomography. Spanin-mediated membrane fusion triggers bacterial lysis and the explosive discharge of pre-assembled toxins by a subset of the bacterial population.614See Sitsel et al.615Credit: Oleg Sitsel and Stefan Raunser, Max Planck Institute of Molecular Physiology. Cover design: Valentina Monaco",D,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/2_2.png,vith,2_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_1.png,clip,7_1.txt,MAC_Bench/Nature/Cover/Nature Microbiology/3_2.png,MAC_Bench/Nature/Cover/Nature Microbiology/3_2.png,vitg,3_2.txt,MAC_Bench/Nature/Cover/Nature Microbiology/9_11.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_11.png,groundtruth,9_11.txt,train616Biomacromolecules,2025_2,Which of the following options best describe the cover story?,"The cover prominently features a diatom and silicic acid molecule surrounded by macromolecules that represent the organic matrix or the “privileged space” where biosilicification occurs. Macromolecular chemistry guides the formation of their hierarchically structured silica biominerals. This Review of biosilicification literature explores in vivo and in vitro silicification studies and shows there is much to learn about the fundamental processes that control biosilicification. Moving forward, we can use biopolymer chemistry for hypothesis-directed studies to establish biosilicification principles.",B,MAC_Bench/ACS/Cover/Biomacromolecules/2024_10.png,MAC_Bench/ACS/Cover/Biomacromolecules/2024_10.png,clip,2024_10.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2025_2.png,MAC_Bench/ACS/Cover/Biomacromolecules/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2019_7.png,MAC_Bench/ACS/Cover/Biomacromolecules/2019_7.png,vith,2019_7.txt,MAC_Bench/ACS/Cover/Biomacromolecules/2021_8.png,MAC_Bench/ACS/Cover/Biomacromolecules/2021_8.png,vitg,2021_8.txt,train617Cancer Cell,42_12,Which of the following options best describe the cover story?,"On the cover: Routy et al. review the microbiota research in the context of melanoma. The cover image demonstrates618the interplay between melanoma cancer cells and microbiota visually. An intricate619network of lines creates connections that symbolize the link between intestinal bacteria620and melanoma, highlighting the recent research included in the content, visually showcasing621the intricate relationship between the two. Image credit: Simon Rohlen, known as KEF!.",C,MAC_Bench/Cell/Cover/Cancer Cell/23_5.png,MAC_Bench/Cell/Cover/Cancer Cell/23_5.png,vitg,23_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/21_3.png,MAC_Bench/Cell/Cover/Cancer Cell/21_3.png,clip,21_3.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_12.png,MAC_Bench/Cell/Cover/Cancer Cell/42_12.png,groundtruth,42_12.txt,MAC_Bench/Cell/Cover/Cancer Cell/30_5.png,MAC_Bench/Cell/Cover/Cancer Cell/30_5.png,ave_1,30_5.txt,train622Nature Water,2_10,Which of the following options best describe the cover story?,"Linking water and ecosystems623Ecohydrology utilizes the knowledge of both ecological and hydrological processes across various scales. It focuses on the complex interactions between water and ecosystems: how water affects the ecological systems and how ecosystems, in turn, influence the water cycle and water quality. Research in ecohydrology aims to advance the understanding of the interactions and to provide solutions that contribute to enhancing ecosystem conservation and sustainable water resource management.624The cover shows a UNESCO Ecohydrology Demonstration Site: the area of Lake Wood, part of the Eddleston Water Project near Peebles, UK. The Eddleston Water Project serves as a dynamic testing ground for natural flood management techniques, which aim to bolster food resilience through the restoration of natural processes that slow water flow and increase water retention within the river system. This project demonstrates how ecohydrology research supports flood risk management, climate change adaptation and biodiversity enhancement at catchment scale.625See Editorial.626Image: Colin McLean Photography. Cover design: Valentina Monaco",B,MAC_Bench/Nature/Cover/Nature Water/2_1.png,MAC_Bench/Nature/Cover/Nature Water/2_1.png,vith,2_1.txt,MAC_Bench/Nature/Cover/Nature Water/2_10.png,MAC_Bench/Nature/Cover/Nature Water/2_10.png,groundtruth,2_10.txt,MAC_Bench/Nature/Cover/Nature Water/2_11.png,MAC_Bench/Nature/Cover/Nature Water/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Water/3_1.png,MAC_Bench/Nature/Cover/Nature Water/3_1.png,vitg,3_1.txt,test627ACS ES&T Air,2024_3,Which of the following options best describe the cover story?,"This study illustrates the molecular composition of organic aerosols collected in the Houston, Texas region using direct sampling interfaced with high-resolution mass spectrometry. This study highlights the episodic prevalence and day/nighttime distribution of organosulfates and organonitrates enriched species.",D,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png,vitg,2024_8.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_9.png,vith,2024_9.txt,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,MAC_Bench/ACS/Cover/ACS ES&T Air/2024_3.png,groundtruth,2024_3.txt,train628Cell Host&Microbe,33_1,Which of the following options best describe the cover story?,"On the cover: This illustration by Jiang et al. metaphorically represents the gut and brain as intricate mazes connected by the vagus629nerve. The NTS (nucleus tractus solitarius) acts as a signal controller, illustrated630as a traffic control center that manages neural signals at the CeA (central amygdala).631Roseburia intestinalis, portrayed as diligent workers in the lush, maze-like forest, produce butyrate, symbolized632by the yellow “fuel”. This butyrate powers the NTS and allows it to signal “red lights”633(inhibitory output) at the CeA, effectively blocking pro-nociceptive signals (the634“cars”) from traveling along the ascending pain pathway from the spinal cord. This635study reveals a mechanism of pain regulation via the gut-brain axis and underscores636the significant influence of microbiota-derived metabolites on pain-related neural637circuitry. This cover image was created by Beatrix Yu, a medical illustrator at CUHK.",B,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_2.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_2.png,clip,33_2.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_1.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/33_1.png,groundtruth,33_1.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/27_5.png,ave_3,27_5.txt,MAC_Bench/Cell/Cover/Cell Host&Microbe/23_3.png,MAC_Bench/Cell/Cover/Cell Host&Microbe/23_3.png,vitg,23_3.txt,train638Bioconjugate Chemistry,2024_6,Which of the following options best describe the cover story?,"A norbornene-containing analogue of farnesyl diphosphate increases the utility of prenyltransferase-catalyzed protein labeling. In one application, a unique subset of prenylated proteins was observed via proteomics. In another",B,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_2.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2012_2.png,ave_1,2012_2.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2024_6.png,groundtruth,2024_6.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_5.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2013_5.png,clip,2013_5.txt,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_6.png,MAC_Bench/ACS/Cover/Bioconjugate Chemistry/2016_6.png,ave_2,2016_6.txt,train639ACS Applied Bio Materials,2024_11,Which of the following options best describe the cover story?,Daima and co-workers discuss engineered nanomaterials,C,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_1.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_1.png,vitg,2024_1.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_3.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_11.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_6.png,vith,2024_6.txt,train640ACS Chemical Biology,2024_11,Which of the following options best describe the cover story?,"The toxicity of a nanopore-forming protein is controlled exclusively using visible light as a result of the incorporation of a water-soluble tetra-ortho-fluoro-substituted azobenzene photoswitch. The geometry of the switch under blue light prevents nanopore formation, while upon green light irradiation, the protein is activated, resulting in targeted cell destruction.",D,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_8.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_8.png,vith,2015_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_2.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_2.png,clip,2015_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_11.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2017_11.png,vitg,2017_11.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_11.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_11.png,groundtruth,2024_11.txt,train641Crystal Growth & Design,2024_11,Which of the following options best describe the cover story?,"The convolution of spatial confinement and interparticle interactions controls the formation of superparticles differing in structure and function, resulting in emergent properties. In this review, Marino et al. discuss recent developments in this topical area spanning length scales of colloidal particle assembly from nano- to micrometers. The cover image was AI-generated using Microsoft Copilot.",C,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2022_2.png,vith,2022_2.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_15.png,vitg,2024_15.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2017_5.png,clip,2017_5.txt,test642Nature Nanotechnology,19_4,Which of the following options best describe the cover story?,"Polariton condensation on the edge643The image presents a topologically protected polariton emission formed by hybridizing optical and excitonic excitations in a halide perovskite microcavity.644See Kai Peng et al.645Image: Kai Peng, Wei Li, and Wei Bao, Rensselaer Polytechnic Institute. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/11_8.png,clip,11_8.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_4.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_4.png,groundtruth,19_4.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png,vitg,19_5.txt,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_8.png,MAC_Bench/Nature/Cover/Nature Nanotechnology/18_8.png,vith,18_8.txt,val646Nature Mental Health,2_1,Which of the following options best describe the cover story?,"Epigenetic signatures of childhood adversity — risk and resilience647Childhood adversity, or the range of negative events that children can experience, encompasses all forms of physical and emotional abuse, neglect, and circumstances such as parental loss and poverty. Childhood adversity is associated with increased physical and mental health conditions, such as cardiovascular disease, alcohol and substance use, and depression. Epigenetic analyses can identify potential biomarkers of childhood adversity, such as DNA methylation that can change gene expression. Our cover depicts children on a playground, but one made of DNA. We chose to focus on one potential indication of methylation, as a biomarker that in some instances indicates reduced risk or resilience.648Read more about the consequences of childhood adversity in our Editorial and see the Article by Lussier et al. to read about epigenetic signatures that mediate the relationship between childhood adversity and depression.649Image: Marina Spence and Hibrida13 / iStock / Getty Images Plus. Cover design: Marina Spence",A,MAC_Bench/Nature/Cover/Nature Mental Health/2_1.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_1.png,groundtruth,2_1.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,clip,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,ave_2,2_6.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_10.png,vitg,2_10.txt,train650Trends in Biochemical Sciences,49_5,Which of the following options best describe the cover story?,"For Gram-negative bacteria to survive and possess virulence, outer651membrane proteins (OMPs) must be properly made and maintained. In their article on652pages 667–680, Taylor Devlin and Dr. Karen Fleming describe the team of chaperones653and proteases with both redundant and unique functions that exist to help unfolded654precursor OMPs traverse the periplasm and facilitate proper OMP assembly at the OM.655Cover art by Anneliese Faustino.",B,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/42_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/42_8.png,vith,42_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_5.png,groundtruth,49_5.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_5.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/45_5.png,clip,45_5.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_7.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/46_7.png,ave_1,46_7.txt,val656ACS Sensors,2024_3,Which of the following options best describe the cover story?,"Ripe pears can undergo alcoholic fermentation. They release ethanol. Our system, based on enzymatic reactions, can image the distribution of ethanol released from pears. In other words, it is a conversion of odor information into visual information. It is expected that intelligent olfactory sensor systems will be used in agriculture, for example, to locate and sort ripe fruit based on odor-visual information.",B,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_4.png,ave_3,2024_4.txt,MAC_Bench/ACS/Cover/ACS Sensors/2024_3.png,MAC_Bench/ACS/Cover/ACS Sensors/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Sensors/2018_12.png,MAC_Bench/ACS/Cover/ACS Sensors/2018_12.png,clip,2018_12.txt,MAC_Bench/ACS/Cover/ACS Sensors/2016_3.png,MAC_Bench/ACS/Cover/ACS Sensors/2016_3.png,vith,2016_3.txt,train657Environment & Health,2024_9,Which of the following options best describe the cover story?,"Toxicological assessment of compounds to aquatic life plays an important role in protecting the water environment from their hazards. We present a web-based server, AquaticTox, for predicting acute toxicity of organic compounds in aquatic organisms. This tool could facilitate the identification of aquatic toxic chemicals and the design of green molecules.",C,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,MAC_Bench/ACS/Cover/Environment & Health/2024_10.png,vith,2024_10.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,MAC_Bench/ACS/Cover/Environment & Health/2024_7.png,clip,2024_7.txt,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,MAC_Bench/ACS/Cover/Environment & Health/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,MAC_Bench/ACS/Cover/Environment & Health/2023_3.png,vitg,2023_3.txt,train658Current Biology,34_11,Which of the following options best describe the cover story?,"On the cover: In this issue, Werner et al. demonstrate that contractile rings undergo speed oscillations that their experimental659and theoretical approaches suggest are due to periodic compaction and remodeling of660the actomyosin cytoskeleton. Here, gray shapes are cytokinetic ring positions in each661time point of timelapse image series for 20 control cells; the direction of furrowing662and the timing of bouts of acceleration and deceleration are random, but speed oscillations663and circumferential travel are consistent. Rainbow traces show speed (y axis) oscillations664of 72 5° segments around the ring of one control cell over time (x axis). Segments665at 3 o’clock (red) take turns being fastest with segments at 8 o’clock (green) and666finally at 10 o’clock (blue); all segments oscillate at a range of frequencies. Image667by Michael Werner and Amy Shaub Maddox.",A,MAC_Bench/Cell/Cover/Current Biology/34_11.png,MAC_Bench/Cell/Cover/Current Biology/34_11.png,groundtruth,34_11.txt,MAC_Bench/Cell/Cover/Current Biology/23_20.png,MAC_Bench/Cell/Cover/Current Biology/23_20.png,clip,23_20.txt,MAC_Bench/Cell/Cover/Current Biology/19_7.png,MAC_Bench/Cell/Cover/Current Biology/19_7.png,vith,19_7.txt,MAC_Bench/Cell/Cover/Current Biology/21_15.png,MAC_Bench/Cell/Cover/Current Biology/21_15.png,vitg,21_15.txt,val668iScience,27_3,Which of the following options best describe the cover story?,"The cover image is a digital artwork visualizing whale songs recorded by an ocean-bottom669seismometer array. Utilizing spectrum analysis and dynamic imaging techniques, Ren et al. created visuals based on the variation in the amplitudes of the seismic waveforms.670The higher amplitude indicates that the recorded noise was closer to the seismometer,671and the greater energy level of the whale song resulted in a more accurate silhouette672of the whale. The authors further integrated artistic methodologies to produce images673and videos from seismic waveforms recorded in the ocean, which enable the general674public to gain a multisensory experience of the ocean soundscape studied by specialists.675Their artwork provides new dimensions of scientific data representation, while its676creation is also driven by the analysis of scientific datasets.",A,MAC_Bench/Cell/Cover/iScience/27_3.png,MAC_Bench/Cell/Cover/iScience/27_3.png,groundtruth,27_3.txt,MAC_Bench/Cell/Cover/iScience/28_3.png,MAC_Bench/Cell/Cover/iScience/28_3.png,vitg,28_3.txt,MAC_Bench/Cell/Cover/iScience/26_10.png,MAC_Bench/Cell/Cover/iScience/26_10.png,vith,26_10.txt,MAC_Bench/Cell/Cover/iScience/14_1.png,MAC_Bench/Cell/Cover/iScience/14_1.png,clip,14_1.txt,val677Precision Chemistry,2024_2,Which of the following options best describe the cover story?,"The first Pd-catalyzed stereospecific C-glycosylation of reversed anomeric stannanes yields non-classical aryl and vinyl C-glycosides in good to excellent yields with exclusive stereocontrol, distinguishing this method as the current state-of-the-art.",A,MAC_Bench/ACS/Cover/Precision Chemistry/2024_2.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_9.png,ave_2,2023_9.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_11.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_11.png,ave_3,2024_11.txt,val678NATURE REVIEWS GENETICS,25_4,Which of the following options best describe the cover story?,"Inspired by the Review on p603.679Cover design: Patrick Morgan",C,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/15_4.png,vitg,15_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_4.png,groundtruth,25_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_5.png,clip,14_5.txt,train680Cell Reports Physical Science,5_6,Which of the following options best describe the cover story?,"On the cover: The cover, crafted by Guiyi Zhou, encapsulates the research of Xu et al. on leveraging advanced AI to transform polymeric gas separation membrane design.681It portrays a “polymer universe,” where dynamic interlocking yellow tracks represent682the complex polymer chains within an amorphous system. Shimmering stars scattered683throughout illustrate the gas molecules, emphasizing the focus on improving gas separation684efficiency. The spacecraft navigating this universe symbolizes the accelerating influence685of AI in propelling innovations in membrane technology.",A,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_6.png,groundtruth,5_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_10.png,ave_1,2_10.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/1_3.png,clip,1_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_2.png,ave_2,2_2.txt,test686Journal of Medicinal Chemistry,2024_18,Which of the following options best describe the cover story?,"The painting conveys an anti-depression theme using a small chemical molecule, S-3a, derived from the modification of the natural product scopolamine. Dark clouds symbolize depression, while S-3a pierces through them like an arrow, allowing the sun to shine on the Earth, symbolizing the treatment of depression.",D,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2021_16.png,clip,2021_16.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_14.png,vith,2022_14.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2020_4.png,ave_3,2020_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_18.png,groundtruth,2024_18.txt,train687Evidence-Based Dentistry,25_2,Which of the following options best describe the cover story?,"In this issue:688This issue covers an eclectic mix of evidence which highlights the enormous depth and diversity of knowledge and skill that it takes to be a practising dentist.689Cover illustration by Gary Neill",D,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_1.png,vitg,25_1.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,clip,24_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,vith,25_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_2.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_2.png,groundtruth,25_2.txt,val690The Journal of Physical Chemistry B,2025_5,Which of the following options best describe the cover story?,This work proposes a machine-learning-assisted solid-state nanopore for automated electrical sensing of vitamin B1 (thiamine) and its phosphorylated derivatives with high accuracy. The study introduces a novel strategy for rapid and precise micronutrient detection with a transverse quantum transport approach.,D,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2022_2.png,vitg,2022_2.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_21.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2023_21.png,vith,2023_21.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2021_5.png,clip,2021_5.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_5.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry B/2025_5.png,groundtruth,2025_5.txt,val691Nature Structural & Molecular Biology,31_4,Which of the following options best describe the cover story?,"Remodeling membranes into phagophore-like cups692Using multiple imaging techniques, both in vitro and in vivo, Mohan, Moparthi et al. show that LCB3 works with the ATG121–ATG5–ATG16L1 complex to remodel flat membranes into membrane cups, providing insights into membrane remodeling processes needed for phagophore formation in non-selective autophagy.693See Mohan, Moparthi et al.694Image: Ann Manner / DigitalVision / Getty images. Cover design: Allen Beattie",A,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_4.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_4.png,groundtruth,31_4.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_1.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/27_1.png,vitg,27_1.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/30_3.png,clip,30_3.txt,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_7.png,MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/26_7.png,vith,26_7.txt,val695Nature Photonics,18_4,Which of the following options best describe the cover story?,"Hyper-Raman optical activity696Hyper-Raman optical activity: circularly polarized infrared photons (red helices) incident on molecules arranged on a helical scaffold (white dots) produce hyper-Raman scattering spectra (multicoloured light regions) that feature chirality.697See Valev et al.698Image: Ventsislav K. Valev (University of Bath) and Kylian Valev (St Gregory's Catholic College Bath). Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Photonics/14_11.png,MAC_Bench/Nature/Cover/Nature Photonics/14_11.png,vitg,14_11.txt,MAC_Bench/Nature/Cover/Nature Photonics/16_6.png,MAC_Bench/Nature/Cover/Nature Photonics/16_6.png,vith,16_6.txt,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,MAC_Bench/Nature/Cover/Nature Photonics/6_11.png,clip,6_11.txt,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,MAC_Bench/Nature/Cover/Nature Photonics/18_4.png,groundtruth,18_4.txt,train699ACS Sustainable Chemistry & Engineering,2025_7,Which of the following options best describe the cover story?,The CO2 tree highlights the breadth of chemical compounds currently accessible from CO2 to illustrate its potential to serve as a carbon source for the future.,A,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2017_10.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2017_10.png,ave_3,2017_10.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2020_12.png,vitg,2020_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2022_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2022_2.png,clip,2022_2.txt,test700Trends in Ecology & Evolution,39_2,Which of the following options best describe the cover story?,"Research on pollinator cognition usually focuses on a single reward701aspect in isolation. However, this does not reflect the complexity of reward types702that703pollinators encounter while foraging, as demonstrated by the Sonoran bumblebee,704Bombus sonorus collecting nectar, a complex mix of chemicals, from mealy sage705Salvia farinacea. On pages 1047–1058, Claire Hemingway and colleagues discuss706how reward complexity can impact pollinator cognition and demonstrate the need to707consider ecologically realistic rewards to fully understand plant–pollinator interactions.708Photo credit: Alexander Wild.",A,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_2.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/39_2.png,groundtruth,39_2.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_3.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/36_6.png,vith,36_6.txt,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/24_6.png,MAC_Bench/Cell/Cover/Trends in Ecology & Evolution/24_6.png,clip,24_6.txt,train709Molecular Cell,85_3,Which of the following options best describe the cover story?,"On the cover: RNA modifications decorate RNA molecules, changing their physico-chemical710properties. Ribosomal RNAs (rRNAs) are heavily modified, with more than 200 modified711sites annotated in human rRNAs. In this issue of Molecular Cell, Milenkovic et al. systematically survey the rRNA modification patterns in development, differentiation,712and disease, finding that they represent epitranscriptomic fingerprints of their cells713and tissues of origin. These fingerprints can be used to predict developmental stages,714tissues, cell types, and cancer from as few as 250 reads. Cover artwork by Queralt715Tolosa (https://www.queralttolosa.com).",B,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,MAC_Bench/Cell/Cover/Molecular Cell/43_1.png,clip,43_1.txt,MAC_Bench/Cell/Cover/Molecular Cell/85_3.png,MAC_Bench/Cell/Cover/Molecular Cell/85_3.png,groundtruth,85_3.txt,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,MAC_Bench/Cell/Cover/Molecular Cell/54_4.png,vith,54_4.txt,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,MAC_Bench/Cell/Cover/Molecular Cell/51_2.png,vitg,51_2.txt,val716Crystal Growth & Design,2024_22,Which of the following options best describe the cover story?,"A three-step bending of a 7-acetoxy-4-methylcoumarin crystal upon UV light irradiation from one side of the crystal: First the crystal shows the action away from the light source, then toward the incident light, and finally again away from the light source. The motion is driven by the photodimerization and amorphization.",B,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2019_3.png,clip,2019_3.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_22.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_22.png,groundtruth,2024_22.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2018_1.png,vith,2018_1.txt,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_5.png,vitg,2024_5.txt,test717Nature Neuroscience,27_2,Which of the following options best describe the cover story?,"Sculpting the brain during pregnancy718In this issue, Pritschet and colleagues offer a detailed map of a female human brain across gestation. Pronounced changes in gray and white matter demonstrate the brain’s capacity for extensive remodeling well into adulthood, paralleling the steep rise in hormone production. Reminiscent of sculpting marble, pregnancy is a transformative period of honing and refinement within the brain.719See Pritschet et al.720Image: Ella Maru Studio . Cover design: Marina Spence",D,MAC_Bench/Nature/Cover/Nature Neuroscience/9_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/9_11.png,clip,9_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/6_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/6_9.png,vith,6_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/8_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/8_8.png,vitg,8_8.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_2.png,groundtruth,27_2.txt,train721Trends in Parasitology,40_3,Which of the following options best describe the cover story?,"Parasitoid wasps are a highly diverse group of insects known for their722parasitic lifestyle. These species have become important models for multiple scientific723fields, including evolutionary biology and biological control. Advances in genomic724resources and research have greatly enhanced our understanding of parasitoid wasp725biology. In this issue of Trends in Parasitology, Ye and co-authors provide a comprehensive726overview of the current state of genome sequencing in parasitoid wasps, highlighting727how these genomic studies have led to significant breakthroughs in understanding the728evolution of parasitoid wasps and the genetic basis of key traits. Image credit: Xinhai729Ye.",B,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,MAC_Bench/Cell/Cover/Trends in Parasitology/34_2.png,vitg,34_2.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/40_3.png,MAC_Bench/Cell/Cover/Trends in Parasitology/40_3.png,groundtruth,40_3.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/35_13.png,MAC_Bench/Cell/Cover/Trends in Parasitology/35_13.png,clip,35_13.txt,MAC_Bench/Cell/Cover/Trends in Parasitology/33_1.png,MAC_Bench/Cell/Cover/Trends in Parasitology/33_1.png,vith,33_1.txt,train730Med,5_5,Which of the following options best describe the cover story?,"On the cover: Xenotransplantation of engineered organs and tissues from different731species offers a promising solution to the major global challenge of finding suitable732donor organs for transplants. Results from early pig-to-human kidney xenotransplant733trials are encouraging, but the interactions between xenotransplanted organs and the734recipient require further characterization. In this issue of Med, Pan et al. apply single-cell sequencing to map the dynamics of xenograft-recipient interactions.735While they observe early signs of antibody-mediated rejection, the porcine kidney736shows evidence of rapid tissue repair after transplantation. These insights can be737used to design new engineered porcine models to optimize patient outcomes after xenotransplantation.",A,MAC_Bench/Cell/Cover/Med/5_5.png,MAC_Bench/Cell/Cover/Med/5_5.png,groundtruth,5_5.txt,MAC_Bench/Cell/Cover/Med/5_7.png,MAC_Bench/Cell/Cover/Med/5_7.png,vitg,5_7.txt,MAC_Bench/Cell/Cover/Med/4_1.png,MAC_Bench/Cell/Cover/Med/4_1.png,ave_1,4_1.txt,MAC_Bench/Cell/Cover/Med/2_7.png,MAC_Bench/Cell/Cover/Med/2_7.png,clip,2_7.txt,train738ACS Chemical Neuroscience,2024_8,Which of the following options best describe the cover story?,"Aberrant aggregation of amyloid-β peptides are considered the primary cause of Alzheimer’s disease. The caffeine-armed molecular tweezer demonstrates significant effectiveness in preventing the self-aggregation of these peptides and disrupting preformed amyloid fibrils through non-covalent interactions, especially π–π stacking with aromatic amino acid residues.",D,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2016_10.png,vith,2016_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_6.png,vitg,2020_6.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,clip,2023_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_8.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_8.png,groundtruth,2024_8.txt,train739BDJ In Practice,38_1,Which of the following options best describe the cover story?,"In this issue...740BDJ In Practice is 10! To celebrate, we assess how far the regulator and regulation has come in that time - for better or for worse",A,MAC_Bench/Nature/Cover/BDJ In Practice/38_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/38_1.png,groundtruth,38_1.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,vith,37_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/34_2.png,vitg,34_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_1.png,clip,36_1.txt,train741Nature Plants,10_5,Which of the following options best describe the cover story?,"Beating the bounds742Membranes host, modulate and coordinate a multitude of cellular activities. Different proteins are localized to different cell membranes, and domains within them, such as RECEPTOR-LIKE PROTEIN 4, which is found at cell edges and particularly at corners.743See Jaillais et al.744Image: Liam Elliot, ENS de Lyon. Cover design: Lauren Heslop",A,MAC_Bench/Nature/Cover/Nature Plants/10_5.png,MAC_Bench/Nature/Cover/Nature Plants/10_5.png,groundtruth,10_5.txt,MAC_Bench/Nature/Cover/Nature Plants/8_8.png,MAC_Bench/Nature/Cover/Nature Plants/8_8.png,ave_3,8_8.txt,MAC_Bench/Nature/Cover/Nature Plants/10_9.png,MAC_Bench/Nature/Cover/Nature Plants/10_9.png,vitg,10_9.txt,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,MAC_Bench/Nature/Cover/Nature Plants/4_9.png,clip,4_9.txt,train745Nature Protocols,20_1,Which of the following options best describe the cover story?,"A bioswitchable delivery system for miRNA therapeutics746This image illustrates a bioswitchable delivery system designed to achieve controlled loading and release of miRNA regulators. A ribonuclease H-sensitive sequence functions as the bioswitchable apparatus, enabling release of the miRNA regulator upon ribonuclease H binding (green). See Li et al.747Image: Yunfeng Lin and Songhang Li, Sichuan University. Cover design: S. Harris.",C,MAC_Bench/Nature/Cover/Nature Protocols/15_3.png,MAC_Bench/Nature/Cover/Nature Protocols/15_3.png,vitg,15_3.txt,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,MAC_Bench/Nature/Cover/Nature Protocols/19_9.png,vith,19_9.txt,MAC_Bench/Nature/Cover/Nature Protocols/20_1.png,MAC_Bench/Nature/Cover/Nature Protocols/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Protocols/14_5.png,MAC_Bench/Nature/Cover/Nature Protocols/14_5.png,clip,14_5.txt,train748Cell Genomics,4_5,Which of the following options best describe the cover story?,"On the cover: One of the X chromosomes in females is inactivated through X chromosome749inactivation (XCI). However, several X-linked genes escape from XCI and contribute750to female-biased gene expression. In this issue of Cell Genomics, Tomofuji et al. develop scLinaX, a new bioinformatics tool to quantify the escape from XCI and elucidate751the sex differences of gene regulation. The cover art depicts leaky lights from the752inactivated X chromosome that represent the escape from XCI. Crafted by Anna Tsukasaki,753this image visually captures the essence of the scLinaX method.",D,MAC_Bench/Cell/Cover/Cell Genomics/3_9.png,MAC_Bench/Cell/Cover/Cell Genomics/3_9.png,vith,3_9.txt,MAC_Bench/Cell/Cover/Cell Genomics/1_3.png,MAC_Bench/Cell/Cover/Cell Genomics/1_3.png,clip,1_3.txt,MAC_Bench/Cell/Cover/Cell Genomics/3_5.png,MAC_Bench/Cell/Cover/Cell Genomics/3_5.png,vitg,3_5.txt,MAC_Bench/Cell/Cover/Cell Genomics/4_5.png,MAC_Bench/Cell/Cover/Cell Genomics/4_5.png,groundtruth,4_5.txt,train754Journal of Medicinal Chemistry,2024_4,Which of the following options best describe the cover story?,"1,2,4-Triazole-3-thione derivative HD2 is a highly potent and selective DCN1 inhibitor with favorable PK properties and low toxicity. Additionally, HD2 effectively relieved Ang II/TGFβ-induced cardiac fibroblast activation in vitro and reduced ISO-induced cardiac fibrosis as well as remodeling in vivo",B,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_9.png,vitg,2022_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_24.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2017_24.png,vith,2017_24.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2010_4.png,clip,2010_4.txt,train755Nature Cardiovascular Research,3_8,Which of the following options best describe the cover story?,"Macrophages improve the function of engineered cardiac microtissue756Hamidzada et al. show that after integration of human embryonic stem cell-derived macrophages into human cardiac microtissue, they adopt the resident fate and improve microtissue function by ingesting stressed cardiomyocytes or their cargo by efferocytosis.757See Hamidzada et al.758Image: Ella Maru Studio. Cover design: Bethany Vukomanovic",C,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_10.png,clip,1_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_8.png,groundtruth,3_8.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_5.png,ave_3,3_5.txt,train759Nature Metabolism,6_3,Which of the following options best describe the cover story?,"Humans lacking GDF15760Humans lacking GDF15 have no overt phenotype, are fertile, and have healthy pregnancies. This finding has potential implications for the development of GDF15-targeting drugs, such as in the context of hyperemesis gravidarum or cachexia. The image depicts humans standing in the shape of a DNA molecule.761See Gurtan et al.762Image: Boris SV / Getty Images. Cover design: Thomas Phillips",A,MAC_Bench/Nature/Cover/Nature Metabolism/6_3.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_3.png,groundtruth,6_3.txt,MAC_Bench/Nature/Cover/Nature Metabolism/4_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/4_5.png,vitg,4_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/2_5.png,MAC_Bench/Nature/Cover/Nature Metabolism/2_5.png,clip,2_5.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_9.png,vith,6_9.txt,train763ACS Sustainable Resource Management,2024_11,Which of the following options best describe the cover story?,"The significance of AI in shaping a sustainable future is undeniable. Thus, ACS Sustainable Chemistry & Engineering and ACS Sustainable Resource Management encourage research articles and perspectives on the application of advanced technologies, which includes AI, for the development of sustainable chemical and engineering systems and resource management.",A,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_11.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_8.png,clip,2024_8.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_12.png,vith,2024_12.txt,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,MAC_Bench/ACS/Cover/ACS Sustainable Resource Management/2024_9.png,ave_1,2024_9.txt,train764Trends in Biotechnology,42_7,Which of the following options best describe the cover story?,"Interactions between algae and the phycosome may impact the productivity765of industrial cultures. This fluorescence microscopy image of an aggregate of Chlorella sp.766SLA-04 and its phycosome underlines the ecological complexity of xenic algal cultures.767In768pages 680-698 of this issue, Miller and colleagues highlight the current understanding769of770the phycosome and some future directions for taking advantage of phycosome ecology771in772production systems. Cover image taken by Isaac Miller at the Center for Biofilm Engineering773in the Imaging Core Facility.",A,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_7.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/42_7.png,groundtruth,42_7.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_2.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/29_2.png,ave_2,29_2.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/30_12.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/30_12.png,clip,30_12.txt,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_1.png,MAC_Bench/Cell/Cover/Trends in Biotechnology/32_1.png,vitg,32_1.txt,train774Science Signaling,2007_403,Which of the following options best describe the cover story?,"COVER This week features a Perspective on hedgehog signaling. The image shows cells close to and more distant from a source of the morphogen Sonic hedgehog. [Image: Christopher Bickel, AAAS]",C,MAC_Bench/Science/Cover/Science Signaling/2_60.png,MAC_Bench/Science/Cover/Science Signaling/2_60.png,vith,2_60.txt,MAC_Bench/Science/Cover/Science Signaling/12_578.png,MAC_Bench/Science/Cover/Science Signaling/12_578.png,clip,12_578.txt,MAC_Bench/Science/Cover/Science Signaling/2007_403.png,MAC_Bench/Science/Cover/Science Signaling/2007_403.png,groundtruth,2007_403.txt,MAC_Bench/Science/Cover/Science Signaling/6_258.png,MAC_Bench/Science/Cover/Science Signaling/6_258.png,vitg,6_258.txt,train775Nature Microbiology,9_1,Which of the following options best describe the cover story?,"Avian influenza in Antarctica776The International high pathogenicity avian influenza (HPAI) Australis Expedition 2024 monitored the spread of HPAI virus in Antarctica. A molecular diagnostic laboratory was set up on board the sailing boat Australis depicted in this image. Aguado et al. discuss the aims, challenges and learnings from this expedition, and how on-site diagnostics can be valuable for real-time surveillance of infectious disease outbreaks amongst wildlife.777See Aguado et al.778Image: Antonio Alcamí, Centro de Biología Molecular Severo Ochoa. Cover design: Laoise Mac Gabhann",A,MAC_Bench/Nature/Cover/Nature Microbiology/9_1.png,MAC_Bench/Nature/Cover/Nature Microbiology/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_6.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/Nature Microbiology/7_11.png,MAC_Bench/Nature/Cover/Nature Microbiology/7_11.png,ave_3,7_11.txt,MAC_Bench/Nature/Cover/Nature Microbiology/8_7.png,MAC_Bench/Nature/Cover/Nature Microbiology/8_7.png,ave_2,8_7.txt,train779ACS Chemical Biology,2024_7,Which of the following options best describe the cover story?,"Measuring the cell penetration of biotherapeutics is challenging. New techniques are revealing precisely how much of a peptide or oligonucleotide drug penetrates to the cytosol or nucleus of target cells. Excitingly, these techniques are now being used to reveal differential penetration into different cell types, allowing drug developers to better understand how these drugs get into cells and what governs their cell-type selectivity. Cover art was generated with the assistance of Canva Magic Studio and Adobe Photoshop.",B,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_5.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2016_5.png,vitg,2016_5.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_7.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2015_4.png,ave_2,2015_4.txt,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,MAC_Bench/ACS/Cover/ACS Chemical Biology/2019_9.png,clip,2019_9.txt,train780NATURE REVIEWS DRUG DISCOVERY,23_5,Which of the following options best describe the cover story?,"A pharmacological concerto, inspired by the Perspective on p626.781Cover design: S. Harris",A,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_5.png,groundtruth,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/19_7.png,vith,19_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_4.png,vitg,23_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/22_8.png,clip,22_8.txt,train782Science Signaling,2007_398,Which of the following options best describe the cover story?,"COVER This week's Focus Issue, published to complement the Science Special Issue on Challenges in Immunology, contains an Editorial Guide, a Review, and two Perspectives that discuss signals that affect the fate and responsiveness of T lymphocytes. The image depicts the activation of a naïve CD4+ T lymphocyte by a dendritic cell and its subsequent expansion and differentiation into a long-lived memory cell. [Image: Preston Huey, AAAS]",B,MAC_Bench/Science/Cover/Science Signaling/5_230.png,MAC_Bench/Science/Cover/Science Signaling/5_230.png,clip,5_230.txt,MAC_Bench/Science/Cover/Science Signaling/2007_398.png,MAC_Bench/Science/Cover/Science Signaling/2007_398.png,groundtruth,2007_398.txt,MAC_Bench/Science/Cover/Science Signaling/16_810.png,MAC_Bench/Science/Cover/Science Signaling/16_810.png,vitg,16_810.txt,MAC_Bench/Science/Cover/Science Signaling/8_366.png,MAC_Bench/Science/Cover/Science Signaling/8_366.png,vith,8_366.txt,train783Nature Cardiovascular Research,3_11,Which of the following options best describe the cover story?,"A bispecific antibody to treat bleeding disorders784Gandhi, Zivkovic, Østergaard et al. describe a bispecific antibody, HMB-001, that can be used for the potential prophylactic treatment of patients with genetic bleeding disorders.785See Ghandhi et al.786Image: Hemab ApS, Verge Scientific. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_1.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_9.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_9.png,vith,2_9.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_11.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_11.png,groundtruth,3_11.txt,train787Trends in Chemistry,6_6,Which of the following options best describe the cover story?,"Whilst many often look to past giants to find that spark of inspiration,788there is something exciting in looking to the future. For our two-part fifth anniversary789special issue, Trends in Chemistry is amplifying rising stars and emerging leaders790in791chemistry today. Our cover for Part II continues on from Part I, highlighting some792of the793milestones and many paths taken on the 'great career race' for early-career scientists794today. Each running at their own pace, the authors in this special issue are all aiming795to innovate with an impact, solve real-world problems and become inspiring leaders796themselves. Artwork credit: Phillip Krzeminski",B,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_8.png,ave_2,6_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_6.png,groundtruth,6_6.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_5.png,vith,6_5.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_7.png,clip,6_7.txt,train797Nature Ecology & Evolution,8_11,Which of the following options best describe the cover story?,"Tasmanian predator interactions798The spotted-tailed quoll (Dasyurus maculatus, pictured) is a mesopredator that is subordinate to Tasmanian devils ((Sarcophilus harrisii). New genomic data show that quoll genetic structure has increased as devil populations have declined from a fatal, transmissible cancer. Top predators are declining globally, and this study shows that such declines can cause evolutionary responses in other predators, as well as ecological changes in food webs due to reduced competition.799See Beer et al800Image: Sebastian Comte. Cover Design: Allen Beattie.",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_3.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/7_3.png,vitg,7_3.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_11.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_11.png,groundtruth,8_11.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,clip,8_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_2.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_2.png,ave_3,5_2.txt,test801Nature Reviews Electrical Engineering,1_1,Which of the following options best describe the cover story?,"Photonic-crystal surface-emitting lasers is an emerging lasing technology that possess high brightness and high functionalities, while maintaining the merits of semiconductor lasers. The illustration depicts a train of pulsed laser beams emitted from the surface of a Photonic-crystal surface-emitting laser. See Noda.802Image: Susumu Noda, Kyoto University. Cover design: Sam Whitham.",B,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_7.png,vitg,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_1.png,groundtruth,1_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_9.png,ave_3,1_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_2.png,MAC_Bench/Nature/Cover/Nature Reviews Electrical Engineering/1_2.png,clip,1_2.txt,train803NATURE REVIEWS GENETICS,25_8,Which of the following options best describe the cover story?,"Inspired by the Review on p309804Cover design: Patrick Morgan",A,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/25_8.png,groundtruth,25_8.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/24_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/24_1.png,clip,24_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/14_7.png,vith,14_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/19_11.png,MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/19_11.png,vitg,19_11.txt,train805Nature Ecology & Evolution,9_1,Which of the following options best describe the cover story?,"Lemur evolution806Madagascar is home to an extraordinary level of endemic biodiversity, but quantifying this is complicated by cryptic diversity among some genera such as mouse lemurs (genus Microcebus). Van Elst et al. shed light on this by presenting a generalizable, integrative framework to characterize the species diversity of this taxonomically controversial genus, demonstrating that it has been overestimated. The photograph depicts Madame Berthe’s mouse lemur (Microcebus berthae), which may recently have gone extinct, in Menabe Central Forest in Madagascar. In a second paper in this issue, Orkin et al. analyse genome-wide resequencing data from 50 species of lemurs, revealing high levels of genomic diversity and demographic declines consistent with the historic timing of human expansion across the island.807See Tobias van Elst et al. and Joseph D. Orkin et al.808Image: Nick Garbutt. Cover design: Allen Beattie",B,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/2_6.png,ave_2,2_6.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/9_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_8.png,vitg,8_8.txt,train809ACS Infectious Diseases,2024_8,Which of the following options best describe the cover story?,"An efflux pump inhibitor, IITR08367, disrupts bacterial energetics that lead to reduced fosfomycin efflux and biofilm formation in Acinetobacter baumannii.",D,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2018_7.png,vith,2018_7.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2019_5.png,vitg,2019_5.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_2.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2017_2.png,clip,2017_2.txt,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_8.png,groundtruth,2024_8.txt,train810The Journal of Physical Chemistry A,2025_3,Which of the following options best describe the cover story?,"Ab initio trajectory simulations of the reaction between chloramine (NH2Cl) and methoxide ion (CH3O-) reveal a dominant proton transfer and minor SN2 products, consistent with experimental findings. Additionally, novel hydride transfer and unconventional roundabout pathways are observed in the nitrogen-centered reaction.",A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2025_3.png,groundtruth,2025_3.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2023_32.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2023_32.png,ave_2,2023_32.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_19.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2024_19.png,vith,2024_19.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2021_33.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry A/2021_33.png,clip,2021_33.txt,train811Chemical & Biomedical ImagingOpen Access,2024_11,Which of the following options best describe the cover story?,"The CBT-Cys click reaction and its derived reactions (i.e., CHQ-Cys and PMN-Cys) have made outstanding contributions to the design of smart bioimaging probes due to their good biocompatibility and self-assembly properties. In this review, we focus on the concept, mechanism, and research progress of CBT-Cys-like reactions.",C,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_8.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_11.png,groundtruth,2024_11.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_6.png,ave_0,2023_6.txt,train812NATURE REVIEWS NEUROSCIENCE,25_8,Which of the following options best describe the cover story?,"‘The language network’, inspired by the Review on p289.813Cover design: Jennie Vallis",D,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_3.png,vitg,25_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/24_10.png,clip,24_10.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/23_5.png,vith,23_5.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_8.png,groundtruth,25_8.txt,train814Nature Geoscience,17_9,Which of the following options best describe the cover story?,"Mud glorious mud815Human activities have altered the production, transport, and fate of mud and associated organic carbon, with important implications for global carbon cycling. The image shows a mudflat under the bridge to the island Oléron in Charente-Maritime, France.816See Bianchi et al.817Image: Amar and Isabelle Guillen—Guillen Photo LLC/Alamy Stock Photo. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/14_11.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_11.png,vitg,14_11.txt,MAC_Bench/Nature/Cover/Nature Geoscience/5_5.png,MAC_Bench/Nature/Cover/Nature Geoscience/5_5.png,vith,5_5.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_9.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_9.png,groundtruth,17_9.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_10.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_10.png,clip,17_10.txt,train818Nature Food,5_10,Which of the following options best describe the cover story?,"Nutrient retention in aquaculture819Salmon has one of the most efficient feed-to-food conversion rates among farmed animals, but its high trophic level makes salmon aquaculture a major consumer of marine resources — including species that are consumed directly by people, such as herring and mackerel. Re-allocating species currently used in salmon feeds towards direct human consumption can increase the overall amount of nutritious seafood while avoiding increases in wild-caught fish supply. Most edible feed fish contains higher concentrations of omega-3 fatty acids, iodine, calcium, iron and vitamin A than farmed salmon. Nutrient retention approaches can drive better performance of aquaculture and identify pathways towards sustainable growth.820See Willer et al.821Image: Jeff Rotman / Alamy Stock Photo. Cover Design: Tulsi Voralia.",D,MAC_Bench/Nature/Cover/Nature Food/5_6.png,MAC_Bench/Nature/Cover/Nature Food/5_6.png,ave_1,5_6.txt,MAC_Bench/Nature/Cover/Nature Food/1_1.png,MAC_Bench/Nature/Cover/Nature Food/1_1.png,ave_3,1_1.txt,MAC_Bench/Nature/Cover/Nature Food/3_5.png,MAC_Bench/Nature/Cover/Nature Food/3_5.png,clip,3_5.txt,MAC_Bench/Nature/Cover/Nature Food/5_10.png,MAC_Bench/Nature/Cover/Nature Food/5_10.png,groundtruth,5_10.txt,train822NATURE REVIEWS IMMUNOLOGY,24_6,Which of the following options best describe the cover story?,"Sex differences in Immunity, inspired by the Review on p487.823Cover design: Simon Bradbrook",C,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/18_3.png,vitg,18_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_4.png,clip,13_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_6.png,groundtruth,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/13_6.png,ave_1,13_6.txt,val824Nature Aging,4_2,Which of the following options best describe the cover story?,"Nonlinear multi-omics aging825In this issue, Xiaotao Shen, Chuchu Wang and colleagues performed comprehensive multi-omics profiling in a cohort of 108 human participants and reveal nonlinear patterns in molecular markers of aging. The cover shows a heatmap depicting nonlinear changing data.826See Shen et al.827Image: Michael Snyder & Xiaotao Shen. Cover design: Lauren Heslop",B,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,MAC_Bench/Nature/Cover/Nature Aging/1_2.png,clip,1_2.txt,MAC_Bench/Nature/Cover/Nature Aging/4_2.png,MAC_Bench/Nature/Cover/Nature Aging/4_2.png,groundtruth,4_2.txt,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,ave_2,4_11.txt,MAC_Bench/Nature/Cover/Nature Aging/2_6.png,MAC_Bench/Nature/Cover/Nature Aging/2_6.png,vith,2_6.txt,train828Journal of Medicinal Chemistry,2024_9,Which of the following options best describe the cover story?,This cover art illustrates how an optimization of stereochemistry (represented by the chiral molecules in the flasks) and electrostatics (represented by a Tesla coil in the glass container) in a glycomimetic ligand resulted in the formation of an enthalpically driven cooperative hydrogen-bond network with its target DC-SIGN. A generative AI tool (Adobe Firefly) was used to create a part of the artwork. The authors are grateful for the assistance of Dilara Tastan and Serdal Tastan in the creation of the cover art.,A,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_9.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_5.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_5.png,clip,2022_5.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_16.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2022_16.png,ave_1,2022_16.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_12.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2018_12.png,vitg,2018_12.txt,train829Nature Neuroscience,27_3,Which of the following options best describe the cover story?,"AI framework for neural–behavioral modeling830Neural dynamics are complex and simultaneously relate to distinct behaviors. To address these challenges, Sani et al. have developed an AI framework termed DPAD that achieves nonlinear dynamical modeling of neural–behavioral data, dissociates behaviorally relevant neural dynamics, and localizes the source of nonlinearity in the dynamical model. In the cover image, what DPAD does is visualized as separating the ovsubbed erall brain activity into distinct pieces related to specific behaviors and discovering how these pieces fit together to build the overall activity.831See Sani et al.832Image: Ella Maru Studio, Omid Sani, Maryam Shanechi. Cover design: Marina Spence",B,MAC_Bench/Nature/Cover/Nature Neuroscience/11_11.png,MAC_Bench/Nature/Cover/Nature Neuroscience/11_11.png,vitg,11_11.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_3.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_3.png,groundtruth,27_3.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/9_2.png,MAC_Bench/Nature/Cover/Nature Neuroscience/9_2.png,clip,9_2.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/21_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/21_8.png,vith,21_8.txt,train833Developmental Cell,59_1,Which of the following options best describe the cover story?,"On the cover: This is a confocal image of the suprachiasmatic nucleus (SCN), a primary834brain target of retinal ganglion cells (RGC) responsible for circadian rhythms, in835a 6-week-old mouse. The SCN is labeled by intravitreal injection of fluorescent dye-conjugated836cholera toxin B (CTB), which is taken up by RGC. The right eye received Alexa Fluor837647-conjugated CTB and the left eye received Alexa Fluor 555-conjugated CTB to allow838visualization of ipsi- and contralateral projections in each SCN. To learn more about839how regenerating RGC axons can be guided in the mature brain to functionally reconnect840the SCN, see Delpech et al. Image credit: Julia Schaeffer, Homaira Nawabi, and the Photonic Imaging Center of841Grenoble Institute Neuroscience.",C,MAC_Bench/Cell/Cover/Developmental Cell/20_2.png,MAC_Bench/Cell/Cover/Developmental Cell/20_2.png,vith,20_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/18_2.png,MAC_Bench/Cell/Cover/Developmental Cell/18_2.png,clip,18_2.txt,MAC_Bench/Cell/Cover/Developmental Cell/59_1.png,MAC_Bench/Cell/Cover/Developmental Cell/59_1.png,groundtruth,59_1.txt,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,MAC_Bench/Cell/Cover/Developmental Cell/58_24.png,vitg,58_24.txt,train842ACS ES&T Water,2025_1,Which of the following options best describe the cover story?,The front cover by postgraduate student Kemi Oloyede at Imperial College London is part of the Diversity and Inclusion Cover Art Series,A,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_7.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_7.png,ave_2,2021_7.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2021_3.png,ave_3,2021_3.txt,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_6.png,MAC_Bench/ACS/Cover/ACS ES&T Water/2024_6.png,clip,2024_6.txt,train843NATURE METHODS,21_4,Which of the following options best describe the cover story?,"Enhancing lamella preparation for cryo-ET with serial lift-out844Artistic representation of the sectioning step in a focused ion beam-based sample preparation technique, Serial Lift-Out. A block of vitreously frozen biological material (here, a C. elegans L1 larva embedded in buffer) is attached to a micromanipulator needle and transferred to a rectangular-mesh copper electron microscopy grid to be serially sectioned.845See Article846Image: Jürgen M. Plitzko. Cover design: Thomas Phillips",D,MAC_Bench/Nature/Cover/NATURE METHODS/12_7.png,MAC_Bench/Nature/Cover/NATURE METHODS/12_7.png,vitg,12_7.txt,MAC_Bench/Nature/Cover/NATURE METHODS/16_5.png,MAC_Bench/Nature/Cover/NATURE METHODS/16_5.png,clip,16_5.txt,MAC_Bench/Nature/Cover/NATURE METHODS/17_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/17_4.png,vith,17_4.txt,MAC_Bench/Nature/Cover/NATURE METHODS/21_4.png,MAC_Bench/Nature/Cover/NATURE METHODS/21_4.png,groundtruth,21_4.txt,train847Structure,32_12,Which of the following options best describe the cover story?,"On the cover: The cover figure depicts the complex structure of the bacteriophage848HRP29 virion. A novel tail adapter protein is utilized to create a hybrid tail that849has unique receptor binding properties. Subramanian et al. utilized cryo-electron microscopy to deduce how all of the structural proteins come850together to form this phage. They used a variety of biological assays such as temperature851sensitivity assays and CRISPR-Cas knockdowns to determine essential protein building852blocks that help stabilize this phage and are critical for infection. Image credit:853Júlio Arvellos.",D,MAC_Bench/Cell/Cover/Structure/32_5.png,MAC_Bench/Cell/Cover/Structure/32_5.png,vitg,32_5.txt,MAC_Bench/Cell/Cover/Structure/19_8.png,MAC_Bench/Cell/Cover/Structure/19_8.png,vith,19_8.txt,MAC_Bench/Cell/Cover/Structure/22_7.png,MAC_Bench/Cell/Cover/Structure/22_7.png,clip,22_7.txt,MAC_Bench/Cell/Cover/Structure/32_12.png,MAC_Bench/Cell/Cover/Structure/32_12.png,groundtruth,32_12.txt,train854Nature Reviews Rheumatology,20_9,Which of the following options best describe the cover story?,"Inspired by the Review on p241.855Cover design: Steven Hall",A,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_9.png,groundtruth,20_9.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png,vitg,20_11.txt,train856Science,387_6733,Which of the following options best describe the cover story?,"COVER Cultural reverence toward tigers (Panthera tigris) has fostered tolerance and permitted coexistence with humans in India. Ecological restoration, socioeconomic policies, and political stability have facilitated the recovery of tigers within their historical range, despite high human densities. This tigress has reclaimed the ancient fort within Bandhavgarh Tiger Reserve and made it her home. See page 505.857Photo: Yashpal Rathore",B,MAC_Bench/Science/Cover/Science/353_6307.png,MAC_Bench/Science/Cover/Science/353_6307.png,ave_2,353_6307.txt,MAC_Bench/Science/Cover/Science/387_6733.png,MAC_Bench/Science/Cover/Science/387_6733.png,groundtruth,387_6733.txt,MAC_Bench/Science/Cover/Science/359_6374.png,MAC_Bench/Science/Cover/Science/359_6374.png,clip,359_6374.txt,MAC_Bench/Science/Cover/Science/325_5940.png,MAC_Bench/Science/Cover/Science/325_5940.png,vith,325_5940.txt,val858ACS Nanoscience Au,2024_2,Which of the following options best describe the cover story?,"Many metal nanoparticles adopt a face centered cubic (fcc) crystal structure, as shown on the cover. The surfaces of four facets of this fcc nanoparticle are highlighted on the nanoparticle. Enlarged regions of the atomic arrangements of the surfaces of these facets are shown, along with the subsurface atoms.",B,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_5.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2023_5.png,clip,2023_5.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2024_3.png,ave_3,2024_3.txt,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,MAC_Bench/ACS/Cover/ACS Nanoscience Au/2022_4.png,vitg,2022_4.txt,train859Chemical & Biomedical ImagingOpen Access,2024_2,Which of the following options best describe the cover story?,Correlating the subcellular location of essential metals and proteins in neurons using fluorescence light microscopy and synchrotron X-ray fluorescence imaging under cryogenic conditions to preserve native cell structure and bio-molecule distribution. Part of this cover was created using AI Copilot Designer.,B,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_1.png,clip,2023_1.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_2.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2023_5.png,vitg,2023_5.txt,train860Molecular Pharmaceutics,2024_4,Which of the following options best describe the cover story?,"The cover shows a novel therapeutic fusion protein that occurs as a homodimer. One monomer is colored according to the hydrogen exchange results, and the other monomer is colored according to the computational modeling results, both performed to understand the sites responsible for reversible self-association. The methodologies are indicated schematically, and the dual-colored dimer indicates the symbiosis of these methodologies.",A,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_4.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_4.png,groundtruth,2024_4.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_6.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2020_6.png,clip,2020_6.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_2.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2025_2.png,vith,2025_2.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2022_8.png,vitg,2022_8.txt,train861Trends in Biochemical Sciences,50_1,Which of the following options best describe the cover story?,"Heat shock activates a gene expression program to prevent irreversible862damage to macromolecules. On pages 18–32 in this issue, Desroches Altamirano863and Alberti explore how heat shock affects the protein “building blocks’’ in a cell864and865how this promotes a stress response. Heat shock inactivates certain protein blocks,866connects them into larger structures with mRNA and represses general protein867synthesis. Simultaneously, other protein blocks facilitate the synthesis of first-aid868protein blocks (HSPs) to help restore protein blocks with “compromised” structure.869Illustrated by Dr. Desroches Altamirano.",D,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/44_9.png,ave_2,44_9.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/41_8.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/41_8.png,ave_3,41_8.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_2.png,clip,50_2.txt,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_1.png,MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/50_1.png,groundtruth,50_1.txt,val870ACS Chemical Neuroscience,2024_2,Which of the following options best describe the cover story?,"Amyloid fibrils can be generated from a large range of food proteins, which may directly contact disease-associated amyloidogenic proteins in certain scenarios, such as for medical applications or individuals with digestive disorders. In this study, we show the biological effects of food amyloid fibrils when exposed to a series of conventional cell lines.",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_2.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2017_3.png,clip,2017_3.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_7.png,vith,2023_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_5.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2021_5.png,ave_2,2021_5.txt,train871Nature Ecology & Evolution,8_2,Which of the following options best describe the cover story?,"Underwater alliances872Individuals of the day octopus (Octopus cyanea) sometimes team up with various fish species such as the blue goldsaddle goatfish (Parupeneus cyclostomus) to engage in collective hunting. Three-dimensional field-based tracking and field experiments unravel the complex social influences that drive decision-making, and reveal shared leadership across these distantly related species.873See Eduardo Sampaio et al.874Image: Eduardo Sampaio. Cover design: Allen Beattie",C,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/4_6.png,vith,4_6.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/5_8.png,clip,5_8.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_2.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/6_1.png,MAC_Bench/Nature/Cover/Nature Ecology & Evolution/6_1.png,vitg,6_1.txt,train875NATURE IMMUNOLOGY,25_6,Which of the following options best describe the cover story?,"Immune signatures of pain876Single-cell transcriptomics is used to determine the gene signature of infiltrating immune cells and potential cell–cell interactions between receptors, ligands, ion channels and metabolites expressed on immune cells and sensory neurons in three models of inflammatory pain.877See Jain et al.878Image: Sara Hakim, Boston Children’s Hospital. Cover design: Emily Paul",C,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/11_12.png,clip,11_12.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/22_5.png,vitg,22_5.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_6.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_6.png,groundtruth,25_6.txt,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_10.png,MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/10_10.png,vith,10_10.txt,test879Cell Reports Methods,4_9,Which of the following options best describe the cover story?,"On the cover: In this issue, Waas et al. develop an accessible, low-input proteomics platform called DROPPS. The cover image880is an artistic rendering of the proteomics platform where the disco balls, generated881from heatmaps, represent cellular heterogeneity. Image credit: Matthew Waas, PhD.",D,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_5.png,vith,2_5.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,MAC_Bench/Cell/Cover/Cell Reports Methods/2_11.png,clip,2_11.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,MAC_Bench/Cell/Cover/Cell Reports Methods/3_2.png,ave_2,3_2.txt,MAC_Bench/Cell/Cover/Cell Reports Methods/4_9.png,MAC_Bench/Cell/Cover/Cell Reports Methods/4_9.png,groundtruth,4_9.txt,val882Science Robotics,9_94,Which of the following options best describe the cover story?,"ONLINE COVER Grasping Objects with Prosthetics. Amputation of a limb can affect the ability of an amputee to carry out simple tasks, such as grasping an object. Several prosthetic devices rely on the use of electrical signals from nerves and muscles to control their motion. Gherardini et al. have developed an approach that uses implanted magnets that harness muscle deformation to control a myokinetic prosthetic hand. A participant with a transradial amputation recruited for the study showed the ability to carry out functional tests to demonstrate dexterous motor skills. This month’s cover is an image of the participant’s prosthetic hand grasping a clothespin. Credit: OneFrame Creative Science Communication",D,MAC_Bench/Science/Cover/Science Robotics/8_83.png,MAC_Bench/Science/Cover/Science Robotics/8_83.png,clip,8_83.txt,MAC_Bench/Science/Cover/Science Robotics/7_72.png,MAC_Bench/Science/Cover/Science Robotics/7_72.png,ave_2,7_72.txt,MAC_Bench/Science/Cover/Science Robotics/7_67.png,MAC_Bench/Science/Cover/Science Robotics/7_67.png,vitg,7_67.txt,MAC_Bench/Science/Cover/Science Robotics/9_94.png,MAC_Bench/Science/Cover/Science Robotics/9_94.png,groundtruth,9_94.txt,test883Trends in Pharmacological Sciences,46_2,Which of the following options best describe the cover story?,"Recent studies have highlighted the complexity of platelet biology, revealing884their diverse roles beyond hemostasis. Pathological platelet activation is now recognized885as886a key contributor to thrombosis and inflammation, both of which are central to cardiovascular887disease (CVD). Emerging research emphasizes the considerable impact of demographic888factors—such as age, sex, race, and ethnicity—on CVD risk and responses to antiplatelet889therapies. In this issue, Jain, Tyagi and colleagues review the influence of genetic890and non-genetic891factors including age, sex, race, and ethnicity on platelet function and responses892to893antiplatelet therapies. They emphasize the pressing need for further research into894platelet895biology and cardiovascular outcomes across diverse populations and advocate for tailored896therapeutic approaches in CVD based on recent demographic findings. The cover image,897conceptualized and designed by Kanika Jain and Tarun Tyagi using BioRender, features898a899heart, representing cardiovascular health, and hands holding platelets and medications,900symbolizing the interplay between pathological platelet activation—associated with901thrombosis—and therapeutic strategies crucial for CVD management. The diverse902individuals illustrate the impact of demographic factors on CVD risk. Images of heart903and904hands are from Adobe Stock images.",C,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_11.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/40_11.png,ave_3,40_11.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_3.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/42_3.png,vitg,42_3.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_2.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_2.png,groundtruth,46_2.txt,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_1.png,MAC_Bench/Cell/Cover/Trends in Pharmacological Sciences/46_1.png,clip,46_1.txt,train905Nature Neuroscience,27_1,Which of the following options best describe the cover story?,"Focus on single-cell genomics in neuroscience906Single-cell and single-nucleus genomics pave the way for a comprehensive understanding of the nervous system and its diverse cell populations. Realizing this potential depends on meticulous planning, execution, and analysis. In this Focus Issue, three reviews from leaders in the field summarize best practices. The cover illustration symbolizes this effort with two hands pulling on a string, unraveling the complexity of the nervous system.907See Gokce et al. , Nowakowski et al. and Liddelow et al.908Image: Tyas Widayati. Cover design: Marina Spence",C,MAC_Bench/Nature/Cover/Nature Neuroscience/14_8.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_8.png,vith,14_8.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/21_9.png,MAC_Bench/Nature/Cover/Nature Neuroscience/21_9.png,vitg,21_9.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/27_1.png,MAC_Bench/Nature/Cover/Nature Neuroscience/27_1.png,groundtruth,27_1.txt,MAC_Bench/Nature/Cover/Nature Neuroscience/14_3.png,MAC_Bench/Nature/Cover/Nature Neuroscience/14_3.png,clip,14_3.txt,train909Industrial & Engineering Chemistry Research,2024_2,Which of the following options best describe the cover story?,"There have been many recent advancements in regulating microenvironments to enhance CO2 conversion, focusing on copper-based catalysts, featuring strategies like single-atom catalyst design, particle size/facets/morphology control, confinement effects, and interfacial engineering to optimize active site density, control reactant/intermediate concentrations, and promote charge transfer processes.",C,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_23.png,vith,2022_23.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_2.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_19.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_19.png,clip,2021_19.txt,train910Precision Chemistry,2024_10,Which of the following options best describe the cover story?,Thio ligand-modified Au nanoparticles as an extraordinary electrocatalyst enhanced the electroreduction of nitrate to ammonia due to the regulated electronic structure.,D,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_4.png,clip,2024_4.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_8.png,vitg,2023_8.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_7.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_7.png,ave_2,2023_7.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_10.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_10.png,groundtruth,2024_10.txt,train911ACS Applied Optical Materials,2024_9,Which of the following options best describe the cover story?,"A multishell nanoparticle comprised of an ultrabright perovskite core and a nitric oxide sensitive orange-fluorescent emitting dye facilitating real-time imaging and ratiometric biosensing, especially in deep tissue.",B,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_6.png,clip,2024_6.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_2.png,vitg,2023_2.txt,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,MAC_Bench/ACS/Cover/ACS Applied Optical Materials/2023_1.png,ave_3,2023_1.txt,train912Current Biology,34_24,Which of the following options best describe the cover story?,"On the cover: Orchid mantis Hymenopus coronatus, distributed in the tropical areas of China and Southeast Asia, is famous for its913floral resemblance, which has been considered as an example of flower mimicry for914over 200 years. However, in this issue, Zhao et al. document its gliding performance and show that the petal-shaped femoral lobes are915crucial for gliding. Behavioral and morphological analyses suggest that gliding might916be the evolutionary motivation of these lobes. Image by Xin Zhao.",C,MAC_Bench/Cell/Cover/Current Biology/18_6.png,MAC_Bench/Cell/Cover/Current Biology/18_6.png,vith,18_6.txt,MAC_Bench/Cell/Cover/Current Biology/32_10.png,MAC_Bench/Cell/Cover/Current Biology/32_10.png,clip,32_10.txt,MAC_Bench/Cell/Cover/Current Biology/34_24.png,MAC_Bench/Cell/Cover/Current Biology/34_24.png,groundtruth,34_24.txt,MAC_Bench/Cell/Cover/Current Biology/30_22.png,MAC_Bench/Cell/Cover/Current Biology/30_22.png,vitg,30_22.txt,test917Industrial & Engineering Chemistry Research,2024_33,Which of the following options best describe the cover story?,The cover sketches the challenge of integrating multiple scales into a process model and how this can be performed with compartment models. These compartment models are applied to an industrial rotary dryer shown in the figures and the background.,B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_12.png,ave_2,2020_12.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_33.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_33.png,groundtruth,2024_33.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_51.png,ave_1,2024_51.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_4.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2020_4.png,clip,2020_4.txt,train918Science Advances,11_8,Which of the following options best describe the cover story?,"ONLINE COVER Artistic rendering of a universal prion-based mechanism for ionic strength sensing (represented by gauge) inside animal cells. An ever-expanding fraction of the global population faces rising temperatures and water scarcity, conditions that place excessive ionic stress on cells and tissues. Khandwala et al. show that increasing ionic strength inside cells activates a mitigative transcriptional program controlled by the protein NFAT5. This discovery links climate medicine and cell biology, providing a foundation for developing therapies against climate change-associated diseases, including chronic kidney disease. Credit: Kate Zvorykina and Ella Marushchenko (Ella Maru Studio, Inc.)",C,MAC_Bench/Science/Cover/Science Advances/9_14.png,MAC_Bench/Science/Cover/Science Advances/9_14.png,vitg,9_14.txt,MAC_Bench/Science/Cover/Science Advances/9_20.png,MAC_Bench/Science/Cover/Science Advances/9_20.png,clip,9_20.txt,MAC_Bench/Science/Cover/Science Advances/11_8.png,MAC_Bench/Science/Cover/Science Advances/11_8.png,groundtruth,11_8.txt,MAC_Bench/Science/Cover/Science Advances/9_23.png,MAC_Bench/Science/Cover/Science Advances/9_23.png,ave_1,9_23.txt,train919Cancer Cell,42_9,Which of the following options best describe the cover story?,"On the cover: In this issue of Cancer Cell, two papers by Barisic et al. and Deng et al. evaluate how mutations in components of the BAF complex lead to the development of920B cell malignancies. In the cover, Barisic et al. demonstrate that ARID1A is required921for continuous eviction of nucleosomes, facilitating the sequential binding of transcription922factors necessary for safeguarding germinal center B cell fate towards plasma cells.923The cover image symbolizes ARID1A as Sisyphus, exerting significant effort and energy924to push boulders uphill, analogous to the BAF complex and ARID1A using energy from925ATP hydrolysis for nucleosome eviction. Birds in the image symbolize the antibodies926produced by plasma cells when ARID1A effectively remodels nucleosomes. Credit: Art927by Inmywork Studio.",A,MAC_Bench/Cell/Cover/Cancer Cell/42_9.png,MAC_Bench/Cell/Cover/Cancer Cell/42_9.png,groundtruth,42_9.txt,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,MAC_Bench/Cell/Cover/Cancer Cell/23_2.png,vith,23_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/32_2.png,MAC_Bench/Cell/Cover/Cancer Cell/32_2.png,clip,32_2.txt,MAC_Bench/Cell/Cover/Cancer Cell/22_1.png,MAC_Bench/Cell/Cover/Cancer Cell/22_1.png,vitg,22_1.txt,train928Current Biology,34_14,Which of the following options best describe the cover story?,"On the cover: In this issue, Chiarenza et al. reconstruct the evolution of dinosaur climatic niche, showing that ornithischians929and theropods developed broad climatic tolerances in the Early Jurassic, contrasting930with sauropodomorphs’ temperature conservatism. Broad niches in ornithischians and931theropods suggest “warm-bloodedness,” while sauropodomorphs' conservatism implies932“cold-bloodedness.” The dromaeosaurid theropod on the cover, which we reconstruct933as a likely homeotherm, is warming its nest amid a rigid and cold environment, evoking934the link between the evolution of thermophysiology and climate documented in this935paper. Image © Davide Bonadonna; used with permission.",C,MAC_Bench/Cell/Cover/Current Biology/27_4.png,MAC_Bench/Cell/Cover/Current Biology/27_4.png,clip,27_4.txt,MAC_Bench/Cell/Cover/Current Biology/32_19.png,MAC_Bench/Cell/Cover/Current Biology/32_19.png,vith,32_19.txt,MAC_Bench/Cell/Cover/Current Biology/34_14.png,MAC_Bench/Cell/Cover/Current Biology/34_14.png,groundtruth,34_14.txt,MAC_Bench/Cell/Cover/Current Biology/26_15.png,MAC_Bench/Cell/Cover/Current Biology/26_15.png,ave_1,26_15.txt,train936ACS Synthetic Biology,2025_1,Which of the following options best describe the cover story?,"The key economic indicators, namely, titer, rate, and yield (TRY) that, respectively, reflect the downstream processing, reactor size, and raw material costs, serve as useful ways to benchmark intensified fermentation processes. BioTRY provides a user-friendly interface for querying, browsing, and visualizing TRY records in microbial processes.",C,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_2.png,clip,2025_2.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2023_9.png,vitg,2023_9.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_1.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2012_5.png,MAC_Bench/ACS/Cover/ACS Synthetic Biology/2012_5.png,ave_2,2012_5.txt,train937CELL RESEARCH,34_6,Which of the following options best describe the cover story?,"The SCN is the central biological clock with thousands of twinking neurons as the time-keeping elements. At the system level, bilaterally symmetrical ripple-like patterns emerge from the functional organization of these neurons, aesthetically pleasing like that of a butterfly.",B,MAC_Bench/Nature/Cover/CELL RESEARCH/33_11.png,MAC_Bench/Nature/Cover/CELL RESEARCH/33_11.png,ave_3,33_11.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_6.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_6.png,groundtruth,34_6.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,MAC_Bench/Nature/Cover/CELL RESEARCH/34_10.png,clip,34_10.txt,MAC_Bench/Nature/Cover/CELL RESEARCH/32_5.png,MAC_Bench/Nature/Cover/CELL RESEARCH/32_5.png,ave_2,32_5.txt,train938Nature Electronics,7_6,Which of the following options best describe the cover story?,"Light-touch electronics with a spin939Imperceptible electronic fibres can be tethered to biological surfaces with an orbital spinning technique and used to create on-skin electrodes that can detect electrocardiogram signals, skin-gated organic electrochemical transistors, and augmented touch and plant interfaces. The photograph on the cover shows the fibres on one person’s finger, where they can be used to record electrocardiograms of another person by touching the other person’s finger.940See Wang et al. and News & Views by Wan et al.941Image: Wenyu Wang and Yuan Shui, University of Cambridge. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,MAC_Bench/Nature/Cover/Nature Electronics/1_1.png,vitg,1_1.txt,MAC_Bench/Nature/Cover/Nature Electronics/4_10.png,MAC_Bench/Nature/Cover/Nature Electronics/4_10.png,clip,4_10.txt,MAC_Bench/Nature/Cover/Nature Electronics/7_6.png,MAC_Bench/Nature/Cover/Nature Electronics/7_6.png,groundtruth,7_6.txt,MAC_Bench/Nature/Cover/Nature Electronics/6_5.png,MAC_Bench/Nature/Cover/Nature Electronics/6_5.png,vith,6_5.txt,val942ACS Biomaterials Science & Engineering,2025_1,Which of the following options best describe the cover story?,Morphology staining images of mouse oligodendrocyte progenitor cells cultured alongside electrospun fibers in 3D hydrogels. Cells grown alongside fibers extended numerous branchlike processes throughout the hydrogel.,A,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2025_1.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2015_6.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2015_6.png,vitg,2015_6.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2018_9.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2018_9.png,vith,2018_9.txt,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2021_9.png,MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2021_9.png,clip,2021_9.txt,val943Trends in Endocrinology & Metabolism,35_8,Which of the following options best describe the cover story?,"Recent advances in FGF21 biology and pharmacology have led to944clinical trials testing long-acting FGF21 analogues and antibody-based mimetics945for the treatment of obesity-related metabolic comorbidities. This month, Xu and946colleagues (pp 371—384) discuss the challenges and future directions in the clinical947implementation of FGF21-based drugs for metabolic disorders. The cover image948depicts a warrior fighting obesity-related comorbidities: his shield, showing the949structure of FGF21, symbolizes the protective roles of FGF21 analogues in alleviating950MASH and hypertriglyceridemia, whereas his knife and armor represent the therapeutic951potential of combination therapy based on FGF21 analogues and other hormones952against metabolic diseases. Artwork credit: Zara Siu Wa Chui.",B,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_14.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/26_14.png,vith,26_14.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_8.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_8.png,groundtruth,35_8.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_3.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/30_3.png,vitg,30_3.txt,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_6.png,MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/32_6.png,clip,32_6.txt,train953Nature Chemical Biology,20_10,Which of the following options best describe the cover story?,"Concentrated by condensates954Small molecules can concentrate in diverse cellular compartments. The image, captured by two-photon microscopy, shows the accumulation of tryptanthrin, a quinazoline indole alkaloid and active ingredient in medicinal herbs, within biomolecular condensates and cytoplasmic organelles.955See Kilgore et al.956Image: Henry Kilgore, Whitehead Institute for Biomedical Research. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_6.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/14_6.png,vith,14_6.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/17_7.png,clip,17_7.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_8.png,vitg,20_8.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_10.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_10.png,groundtruth,20_10.txt,test957Macromolecules,2025_2,Which of the following options best describe the cover story?,"Introducing a strategy to customize the dynamics of covalent adaptable networks via molecular-scale design. By modifying functional monomer moieties, this strategy adjusts vinylogous bond kinetics, enabling the properties of robustness, dynamics, shape-memory, reprocessibility, and degradation. View the article.",A,MAC_Bench/ACS/Cover/Macromolecules/2025_2.png,MAC_Bench/ACS/Cover/Macromolecules/2025_2.png,groundtruth,2025_2.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,ave_2,2014_20.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_19.png,MAC_Bench/ACS/Cover/Macromolecules/2010_19.png,clip,2010_19.txt,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,MAC_Bench/ACS/Cover/Macromolecules/2021_18.png,ave_1,2021_18.txt,train958NATURE BIOTECHNOLOGY,42_5,Which of the following options best describe the cover story?,"Liposomal antibiotics unleash antitumor immune response959An illustration of liposomal antibiotics (pink lipid particles) targeting tumor-associated bacteria (colored spheres in central purple tumor), leading to activation of T cells (white) by cytokines (orange) released from antigen-presenting cells (not shown). Wang et al. show that killing bacteria in tumors by liposomal delivery of antibiotics generates neoantigens that enhance T cell antitumor immunity in a mouse model of colon cancer.960See Wang et al.961Image: Ella Maru Studio. Cover design: Erin Dewalt",B,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_12.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/39_12.png,vitg,39_12.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_5.png,groundtruth,42_5.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/22_5.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/22_5.png,vith,22_5.txt,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/20_1.png,MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/20_1.png,clip,20_1.txt,train962Macromolecules,2024_2,Which of the following options best describe the cover story?,Molecular dynamics simulations of crazes in glassy polymers under cyclic loading reveal the quasi-stress-free motion of craze fibril folding during unloading. View the article.,B,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_2.png,MAC_Bench/ACS/Cover/Macromolecules/2024_2.png,groundtruth,2024_2.txt,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,MAC_Bench/ACS/Cover/Macromolecules/2010_18.png,ave_1,2010_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,MAC_Bench/ACS/Cover/Macromolecules/2014_23.png,vitg,2014_23.txt,train963Trendsin Neurosciences,47_12,Which of the following options best describe the cover story?,"Jumping spiders, renowned for their excellent vision used in prey capture,964navigation, and assessing elaborate, species-specific courtship displays, are an965emerging model system in the study of visual attention. These charismatic spiders966have967eight camera-type eyes: six function as motion detectors, while a pair of highly acute,968moveable eyes allow spiders to inspect the shape and color of objects. Historically,969investigation of visual processing in these animals has been thwarted by their internally970pressurized bodies, but these constraints have been overcome. In this issue of Trends971   in Neurosciences, Alex Winsor, Luke Remage-Healey, Ronald Hoy, and Elizabeth Jakob972highlight the architecture of the jumping spider visual system, discuss how shifts973in974gaze can regulate the uptake of visual information, and describe how different streams975of visual information from multiple eyes might be integrated in the brain. Cover image976of977Phidippus regius by Elizabeth Jakob.",A,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_12.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_12.png,groundtruth,47_12.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_5.png,clip,34_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/43_5.png,vith,43_5.txt,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_9.png,MAC_Bench/Cell/Cover/Trendsin Neurosciences/34_9.png,vitg,34_9.txt,val978ACS Organic & Inorganic Au,2023_1,Which of the following options best describe the cover story?,"A tetrahedral chiral-at-nickel(II) complex has been synthesized using an achiral unsymmetric tridentate ligand, and its structural characteristics have been clarified in detail. Under a low-temperature condition, molecules with the same absolute configuration of the stereogenic nickel(II) center preferentially grow into conglomerate crystals due to the intermolecularly hydrogen-bonded helical structure formation.",B,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png,vith,2023_6.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_1.png,groundtruth,2023_1.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_4.png,ave_2,2023_4.txt,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2024_4.png,clip,2024_4.txt,train979Science Immunology,9_99,Which of the following options best describe the cover story?,"ONLINE COVER IgE Plasma Cells Are Cut from a Different Cloth. Immunoglobulin E–producing plasma cells (IgE PCs) are key players in allergic reactions and are an attractive target for the treatment of allergic diseases. A deeper understanding of IgE PC phenotypic and transcriptional profiles is needed, however. Vecchione et al. characterized IgE PCs from mice exposed to house dust mite allergen. IgE PCs were transcriptionally and phenotypically different from PCs producing other immunoglobulin isotypes, with increased endoplasmic reticulum stress due to higher levels of antibody production. IgE PCs in the lung-draining lymph node (dLN) and bone marrow (BM) showed distinct transcriptional profiles: The relatively short-lived IgE dLN PCs expressed genes indicative of recent class switching, whereas BM PCs were enriched for genes involved in survival and BM homing. This month’s cover illustration depicts plasma cells secreting a profusion of allergy-driving IgE antibodies. Credit: Noelle Burgess/Science Immunology",A,MAC_Bench/Science/Cover/Science Immunology/9_99.png,MAC_Bench/Science/Cover/Science Immunology/9_99.png,groundtruth,9_99.txt,MAC_Bench/Science/Cover/Science Immunology/9_95.png,MAC_Bench/Science/Cover/Science Immunology/9_95.png,vitg,9_95.txt,MAC_Bench/Science/Cover/Science Immunology/8_90.png,MAC_Bench/Science/Cover/Science Immunology/8_90.png,clip,8_90.txt,MAC_Bench/Science/Cover/Science Immunology/9_92.png,MAC_Bench/Science/Cover/Science Immunology/9_92.png,vith,9_92.txt,test980Caner Cell,42_6,Which of the following options best describe the cover story?,"On the cover: Casanova-Salas et al. demonstrate how the genomic and transcriptomic cargo within circulating extracellular981vesicles (EVs) from liquid biopsies provides valuable insights into metastatic prostate982cancer outcomes and treatment responses and how this information could facilitate983the identification of biomarkers for guiding therapy switch decisions. The cover artwork984features an EV-lit traffic light, symbolizing the important role that circulating985EVs could play in the trafficking of clinically actionable information. Image credit:986Carlos Córdoba Terreros.",C,MAC_Bench/Cell/Cover/Caner Cell/34_2.png,MAC_Bench/Cell/Cover/Caner Cell/34_2.png,vith,34_2.txt,MAC_Bench/Cell/Cover/Caner Cell/16_5.png,MAC_Bench/Cell/Cover/Caner Cell/16_5.png,vitg,16_5.txt,MAC_Bench/Cell/Cover/Caner Cell/42_6.png,MAC_Bench/Cell/Cover/Caner Cell/42_6.png,groundtruth,42_6.txt,MAC_Bench/Cell/Cover/Caner Cell/37_5.png,MAC_Bench/Cell/Cover/Caner Cell/37_5.png,clip,37_5.txt,train987Nature Metabolism,6_12,Which of the following options best describe the cover story?,"FASN cuts stress988In this issue of Nature Metabolism, Wei et al. identify a non-fatty acid synthesis function for FASN in suppressing diverse aspects of stress responses through a mechanism that involves FASN cleavage. Depicted are anesthetized C. elegans following stressful conditions.989See Wei et al.990Image: Hai Wei, UT Southwestern Medical Center. Cover Design: Thomas Phillips.",D,MAC_Bench/Nature/Cover/Nature Metabolism/3_9.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_9.png,vitg,3_9.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_12.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_12.png,ave_2,3_12.txt,MAC_Bench/Nature/Cover/Nature Metabolism/3_7.png,MAC_Bench/Nature/Cover/Nature Metabolism/3_7.png,clip,3_7.txt,MAC_Bench/Nature/Cover/Nature Metabolism/6_12.png,MAC_Bench/Nature/Cover/Nature Metabolism/6_12.png,groundtruth,6_12.txt,train991Journal of Agricultural and Food Chemistry,2025_4,Which of the following options best describe the cover story?,"This study investigates a novel antimicrobial peptide AtR905 derived from the endophytic fungus Aspergillus terreus, which was successfully expressed in",B,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2022_48.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2022_48.png,vitg,2022_48.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_4.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2025_4.png,groundtruth,2025_4.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_51.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2021_51.png,clip,2021_51.txt,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2024_45.png,MAC_Bench/ACS/Cover/Journal of Agricultural and Food Chemistry/2024_45.png,vith,2024_45.txt,train992Organometallics,2025_4,Which of the following options best describe the cover story?,"s reactivity trend in activating C(spn)–X bonds mirrors that of a palladium catalyst. Reactivity increases by two distinct mechanisms: i) as the C(spn)–X bond becomes progressively weaker from X = F to Cl to Br to I, resulting in a more facile bond rupture, and ii) as the steric shielding at the pertinent carbon atom diminishes from C(sp3)–X to C(sp2)–X to C(sp)–X, leading to less steric clash and therefore a more stabilizing catalyst–substrate interaction.",D,MAC_Bench/ACS/Cover/Organometallics/2021_9.png,MAC_Bench/ACS/Cover/Organometallics/2021_9.png,clip,2021_9.txt,MAC_Bench/ACS/Cover/Organometallics/2024_16.png,MAC_Bench/ACS/Cover/Organometallics/2024_16.png,ave_1,2024_16.txt,MAC_Bench/ACS/Cover/Organometallics/2024_1.png,MAC_Bench/ACS/Cover/Organometallics/2024_1.png,ave_3,2024_1.txt,MAC_Bench/ACS/Cover/Organometallics/2025_4.png,MAC_Bench/ACS/Cover/Organometallics/2025_4.png,groundtruth,2025_4.txt,train993Trends in Cancer,11_2,Which of the following options best describe the cover story?,"In this issue, Kadali and Shoshani discuss the relationship between994abnormal nuclear structures and the formation of gene amplifications in cancer,995emphasizing their role in tumor heterogeneity and therapy resistance. The cover image996depicts cancer cells breaking chromosome bridges with amplified DNA, generating997ecDNA enclosed within micronuclei. These ecDNA-rich micronuclei, portrayed as998mobile carriers, travel along a winding road symbolizing the dynamic ""route to tumor999evolution."" Along this path, cancer cells act as builders or laborers, depositing1000the1001ecDNA-rich micronuclei into the tumor mass, highlighting their contribution to tumor1002heterogeneity. Cover image design and illustration by Shilpa Madhavan.",B,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,MAC_Bench/Cell/Cover/Trends in Cancer/3_4.png,vith,3_4.txt,MAC_Bench/Cell/Cover/Trends in Cancer/11_2.png,MAC_Bench/Cell/Cover/Trends in Cancer/11_2.png,groundtruth,11_2.txt,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,MAC_Bench/Cell/Cover/Trends in Cancer/10_6.png,vitg,10_6.txt,MAC_Bench/Cell/Cover/Trends in Cancer/6_5.png,MAC_Bench/Cell/Cover/Trends in Cancer/6_5.png,clip,6_5.txt,train1003Journal of Medicinal Chemistry,2024_1,Which of the following options best describe the cover story?,"-A2B-corroles for photodynamic therapy of lung cancer. The lead photosensitizers showed remarkable properties, with IC50 values below 100 nM and no cytotoxicity per se, properties resulting from a synergy between the macrocyclic system and the hydrazone moiety.",C,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_8.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2019_8.png,clip,2019_8.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_13.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2023_13.png,vitg,2023_13.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_1.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_1.png,groundtruth,2024_1.txt,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_13.png,MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2016_13.png,vith,2016_13.txt,val1004ACS Chemical Neuroscience,2024_10,Which of the following options best describe the cover story?,"Induction of acetylation mediated by a CBP/p300-specific KAT activator, TTK21, conjugated to carbon nanosphere (CSP), administrated orally, promotes regeneration and functional recovery of spinal cord (green) injury (red) (partially created with BioRender.com).",A,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_10.png,groundtruth,2024_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_14.png,clip,2022_14.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_12.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2022_12.png,ave_3,2022_12.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_1.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_1.png,ave_2,2023_1.txt,train1005Molecular Pharmaceutics,2024_3,Which of the following options best describe the cover story?,Representation of the disordering effect induced by dibasic calcium phosphate (~the wrecking ball; CSD 31046-I) on carbamazepine dihydrate (~the wall; FEFNOT03) leading to its accelerated dehydration (~expelling of water molecules) during the mixing stage of continuous tablet manufacturing. This work focuses on understanding the mechanism of this excipient-induced effect. The image was created by PfizerWorks Creative Consultancy.,D,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_9.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_9.png,vitg,2021_9.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_3.png,vith,2021_3.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2021_1.png,clip,2021_1.txt,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_3.png,MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_3.png,groundtruth,2024_3.txt,train1006ACS Chemical Neuroscience,2024_7,Which of the following options best describe the cover story?,"The mechanisms accounting for the formation of pores by amyloid peptides are revealed by unbiased all-atom simulations. Peptides adsorb, aggregate into β-sheets, and form pores spontaneously at the surface of lipid bilayers. Four peptides differing in the distribution of polar and nonpolar residues along the sequence are investigated.",B,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_8.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_7.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_10.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_10.png,vith,2020_10.txt,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_3.png,MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2020_3.png,vitg,2020_3.txt,val1007Precision Chemistry,2025_1,Which of the following options best describe the cover story?,"Building two-dimensional, ordered carbon–carbon networks with precise, deterministic monomer coupling at the interface enables the creation of 2D porous, semiconducting nanomembranes.",A,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_6.png,vitg,2024_6.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,MAC_Bench/ACS/Cover/Precision Chemistry/2023_1.png,ave_1,2023_1.txt,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,MAC_Bench/ACS/Cover/Precision Chemistry/2024_5.png,clip,2024_5.txt,train1008NATURE REVIEWS IMMUNOLOGY,24_12,Which of the following options best describe the cover story?,"Myelin sheath repair, inspired by the Review on p49.1009Cover design: Simon Bradbrook",D,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/14_1.png,vitg,14_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/15_3.png,clip,15_3.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/19_6.png,vith,19_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_12.png,MAC_Bench/Nature/Cover/NATURE REVIEWS IMMUNOLOGY/24_12.png,groundtruth,24_12.txt,test1010Nature Astronomy,8_7,Which of the following options best describe the cover story?,"The bated bang behind the burst1011The brightest gamma-ray burst of all time, GRB 221009A, has a fairly modest supernova behind it, according to JWST observations. This finding demonstrates that the GRB and supernova mechanisms are decoupled, and suggests that other factors must be responsible for the extreme energetics involved.1012See Blanchard et al.1013Image: Aaron M. Geller, Northwestern, CIERA & IT Research Computing and Data Services. Cover design: Bethany Vukomanovic.",A,MAC_Bench/Nature/Cover/Nature Astronomy/8_7.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_7.png,groundtruth,8_7.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_1.png,clip,1_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,MAC_Bench/Nature/Cover/Nature Astronomy/1_2.png,vith,1_2.txt,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,MAC_Bench/Nature/Cover/Nature Astronomy/6_7.png,vitg,6_7.txt,test1014NATURE REVIEWS MOLECULAR CELL BIOLOGY,26_1,Which of the following options best describe the cover story?,"‘Understanding cell fate decisions’, inspired by the Review on p111015Cover design: Vicky Summersby",A,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/26_1.png,groundtruth,26_1.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/14_4.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/14_4.png,clip,14_4.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/21_7.png,vith,21_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_8.png,MAC_Bench/Nature/Cover/NATURE REVIEWS MOLECULAR CELL BIOLOGY/23_8.png,vitg,23_8.txt,train1016NATURE ENERGY,9_11,Which of the following options best describe the cover story?,"Protecting the perovskite layer1017The stability of perovskite solar cells under operating conditions remains a challenge. Suo et al. develop a sulfonium-based molecule that affords the perovskite material protection against environmental stress factors like moisture or light irradiation, showing solar cells with negligible efficiency loss after 4,500 hours of operation.1018See Suo et al.1019Image: Dmitry Bogachuk, Solarlab Aiko Europe. Cover design: Thomas Phillips.",A,MAC_Bench/Nature/Cover/NATURE ENERGY/9_11.png,MAC_Bench/Nature/Cover/NATURE ENERGY/9_11.png,groundtruth,9_11.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/4_2.png,MAC_Bench/Nature/Cover/NATURE ENERGY/4_2.png,vith,4_2.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_6.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_6.png,clip,7_6.txt,MAC_Bench/Nature/Cover/NATURE ENERGY/7_1.png,MAC_Bench/Nature/Cover/NATURE ENERGY/7_1.png,ave_2,7_1.txt,train1020Nature Reviews Materials,9_8,Which of the following options best describe the cover story?,"Memristors are two-terminal devices that display memory in the form of electrical resistance. Solution-processed memristors are arising as an attractive technology enabled by the versatility of solution-processed materials, but conscious analysis and demonstration of their performance and reliability are required to enable practical applications. The cover art depicts the opportunity presented by solution-processed methods to synthesize different materials (metal oxides, 2D materials, polymers) to build memristors for potential use in cryptography, data storage and artificial intelligence. See Pazos S et al.1021Cover: David Johnston. The 2D material model is adapted from is adapted from Chen C. et al, Cancer Nanotechnology 13,29 (2022), CC BY 4.0",D,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_11.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/4_11.png,clip,4_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_5.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/8_5.png,vitg,8_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_7.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/1_7.png,ave_2,1_7.txt,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,MAC_Bench/Nature/Cover/Nature Reviews Materials/9_8.png,groundtruth,9_8.txt,train1022Industrial & Engineering Chemistry Research,2024_30,Which of the following options best describe the cover story?,"This paper presents different machine learning algorithms used to predict the production and characteristics of aligned electrospun nanofibers fabricated by the air gap electrospinning method. Classification and regression models are developed using logistic regression, random forest, artificial neural networks, and convolutional neural networks.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_51.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_51.png,clip,2022_51.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_30.png,groundtruth,2024_30.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_6.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_6.png,vitg,2022_6.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_27.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2022_27.png,vith,2022_27.txt,train1023ACS Earth and Space Chemistry,2024_3,Which of the following options best describe the cover story?,"We evaluate the diversity of volatile organic compounds (VOCs) emitted from both pre- and post-harvest 'Alkar' tall wheatgrass, a candidate biofuel. While green leaf volatiles dominate post-harvest emissions, we demonstrate novel post-harvest VOCs that are under-characterized in the context of carbon cycling and atmospheric chemistry.",C,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_11.png,ave_2,2022_11.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,clip,2022_4.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_3.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_3.png,groundtruth,2024_3.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_10.png,vitg,2022_10.txt,train1024ACS Food Science & Technology,2024_9,Which of the following options best describe the cover story?,Controlling the postprandial glucose spike by increasing the rich starch crystallinity and lowering the starch digestion rate of rice-based fermented foods using a combination of heat treatment and hydrocolloid addition.,A,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_9.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_9.png,groundtruth,2024_9.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_8.png,vith,2022_8.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2022_11.png,clip,2022_11.txt,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Food Science & Technology/2023_2.png,ave_1,2023_2.txt,train1025Nature Biomedical Engineering,9_1,Which of the following options best describe the cover story?,"Potent and safer editing via nanoparticle-delivered ribonucleoprotein1026This issue highlights advances in genome editing, including the enhancement of the efficiency and precision of base editing and prime editing, the optimization of the delivery of genome editors and the reduction of off-target effects.1027The cover illustrates lipid nanoparticles optimized for enhancing the stability, delivery efficiency and editing potency of ribonucleoproteins for base editing and prime editing.1028See Hołubowicz et al.1029Image: Image courtesy of Samuel W. Du, University of California, Irvine and Yekaterina Kadyzhevskaya, University of Southern California. Cover design: Alex Wing.",B,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/6_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/6_11.png,clip,6_11.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/9_1.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/9_1.png,groundtruth,9_1.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_8.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_8.png,vith,8_8.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_11.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/5_11.png,vitg,5_11.txt,train1030Caner Cell,43_1,Which of the following options best describe the cover story?,"On the cover: The cover illustrates how glioblastoma (GBM) aligns its growth with1031the brain's daily rhythms. Inspired by artist Sophie Taeuber-Arp and designed by Dr.1032Olivia Walch, this visual highlights the daytime tumor growth driven by the circadian1033surge in glucocorticoids (green dots). Gonzalez-Aponte et al. discover that blocking circadian regulation of glucocorticoid receptor signaling1034slows GBM proliferation in both mouse and human GBM models. Targeting circadian mechanisms1035to combat GBM holds great promise and has significant implications for understanding1036how the circadian system may influence cancer progression, both within the brain and1037beyond.",B,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,MAC_Bench/Cell/Cover/Caner Cell/33_2.png,ave_2,33_2.txt,MAC_Bench/Cell/Cover/Caner Cell/43_1.png,MAC_Bench/Cell/Cover/Caner Cell/43_1.png,groundtruth,43_1.txt,MAC_Bench/Cell/Cover/Caner Cell/26_5.png,MAC_Bench/Cell/Cover/Caner Cell/26_5.png,clip,26_5.txt,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,MAC_Bench/Cell/Cover/Caner Cell/28_4.png,vith,28_4.txt,test1038Journal of Chemical Education,2021_5,Which of the following options best describe the cover story?,"In ""Chiroptical Smart Paints: Polymerization of Helical Structures in Cholesteric Liquid Crystal Films"" (",A,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_5.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_5.png,groundtruth,2021_5.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_1.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_1.png,ave_1,2021_1.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_11.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_11.png,vitg,2020_11.txt,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_10.png,MAC_Bench/ACS/Cover/Journal of Chemical Education/2020_10.png,clip,2020_10.txt,val1039Science Signaling,2007_387,Which of the following options best describe the cover story?,"COVER This week features a Book Review of Regulation of Gene Expression in Plants: The Role of Transcript Structure and Processing, edited by Carole L. Bassett. The image depicts maize with stripes resulting from the movement of transposons. [Image: Alan Rose, University of California, Davis]",C,MAC_Bench/Science/Cover/Science Signaling/11_536.png,MAC_Bench/Science/Cover/Science Signaling/11_536.png,clip,11_536.txt,MAC_Bench/Science/Cover/Science Signaling/5_236.png,MAC_Bench/Science/Cover/Science Signaling/5_236.png,vith,5_236.txt,MAC_Bench/Science/Cover/Science Signaling/2007_387.png,MAC_Bench/Science/Cover/Science Signaling/2007_387.png,groundtruth,2007_387.txt,MAC_Bench/Science/Cover/Science Signaling/1_15.png,MAC_Bench/Science/Cover/Science Signaling/1_15.png,vitg,1_15.txt,train1040Nature Aging,4_7,Which of the following options best describe the cover story?,"Stochasticity in epigenetic clocks1041In this issue, three studies examine the contribution of stochastic epigenetic changes to DNA methylation clocks. Tarkhov et al., Meyer et al. and Tong et al. take different approaches to addressing this question, and concur that stochasticity is involved in epigenetic aging. The cover, from Meyer et al., shows a Galton board, which is a device used to illustrate concepts of probability and stochasticity. At the top, a series of small balls are released, which follow a random path before landing in bins at the bottom. Over many trials, this stochastic process leads to the formation of a normal distributed shape. A clock is depicted within this shape to illustrate that a completely stochastic process can be used to construct aging clocks, consistent with a role of age-dependent increases in stochastic variation in epigenetic processes.1042See Tarkhov et al., Meyer et al. & Tong et al.1043Image: Maayan Visuals. Cover design: Lauren Heslop",C,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,MAC_Bench/Nature/Cover/Nature Aging/4_11.png,ave_3,4_11.txt,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,MAC_Bench/Nature/Cover/Nature Aging/4_8.png,ave_2,4_8.txt,MAC_Bench/Nature/Cover/Nature Aging/4_7.png,MAC_Bench/Nature/Cover/Nature Aging/4_7.png,groundtruth,4_7.txt,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,MAC_Bench/Nature/Cover/Nature Aging/1_1.png,clip,1_1.txt,test1044Science Translational Medicine,17_781,Which of the following options best describe the cover story?,"ONLINE COVER A Noble Pursuit. The cover image shows brain microglia (green) in an intermediate activation state engaging with amyloid plaques (white) in brain tissue from a mouse model of Alzheimer’s disease (AD). Microglia were induced to transition to an intermediate activation state by exposing mice with AD pathology to the anesthetic xenon (Brandao et al.). Xenon, a noble gas, crossed the blood-brain barrier of the mice and promoted microglial activation through interferon-γ signaling. Inhalation of xenon enhanced amyloid plaque compaction in the mouse brain, reduced the number of dystrophic neurites, reduced brain atrophy, and slowed neurodegeneration in three different mouse models of AD. Xenon shows promise as a potential therapeutic for treating AD. Credit: Brandao et alMAC_Bench/Science Translational Medicine",C,MAC_Bench/Science/Cover/Science Translational Medicine/5_206.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_206.png,vitg,5_206.txt,MAC_Bench/Science/Cover/Science Translational Medicine/13_613.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_613.png,clip,13_613.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_781.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_781.png,groundtruth,17_781.txt,MAC_Bench/Science/Cover/Science Translational Medicine/12_563.png,MAC_Bench/Science/Cover/Science Translational Medicine/12_563.png,vith,12_563.txt,train1045Journal of the American Chemical Society,2024_8,Which of the following options best describe the cover story?,"Crystal structure solution methods powered by recent advancements in machine learning reveal the structures of compounds that were previously unsolved. Crystalyze, a model for solving structures from powder X-ray diffraction, has discovered several materials and promises to serve as a generalizable tool for materials discovery under a wide range of conditions. View the article.",A,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_8.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_8.png,groundtruth,2024_8.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_16.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_16.png,vitg,2009_16.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_11.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2016_11.png,vith,2016_11.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,clip,2018_4.txt,val1046Science Immunology,9_92,Which of the following options best describe the cover story?,"ONLINE COVER Treating a Primary Immunodeficiency with CRISPR. Familial hemophagocytic lymphohistiocytosis (FHL) is a range of inherited, sometimes fatal, inflammatory diseases caused by loss-of-function mutations in the cytotoxic machinery of immune cells. Li et al. developed an adeno-associated virus (AAV)–based CRISPR–Cas9 system combined with nonhomologous end joining (NHEJ) inhibition to repair memory T cells from perforin (Prf1)-deficient mice as well as from pediatric patients with FHL2 (PRF1 deficiency) or FHL3 (Munc13-4/UNC13D deficiency). Repaired mouse T cells could then prevent or cure FHL2-like disease in Prf1-knockout mice triggered by Epstein–Barr virus (EBV)–driven B cell hyperproliferation. This month’s cover illustration depicts CRISPR–Cas9–mediated repair of a cytotoxic T cell (red), which allows it to secrete normal cytotoxic granules (pink) and effectively kill virally infected B cells (blue). Credit: A. Fisher/Science Immunology",B,MAC_Bench/Science/Cover/Science Immunology/3_28.png,MAC_Bench/Science/Cover/Science Immunology/3_28.png,clip,3_28.txt,MAC_Bench/Science/Cover/Science Immunology/9_92.png,MAC_Bench/Science/Cover/Science Immunology/9_92.png,groundtruth,9_92.txt,MAC_Bench/Science/Cover/Science Immunology/4_34.png,MAC_Bench/Science/Cover/Science Immunology/4_34.png,vitg,4_34.txt,MAC_Bench/Science/Cover/Science Immunology/6_56.png,MAC_Bench/Science/Cover/Science Immunology/6_56.png,vith,6_56.txt,train1047BDJ In Practice,37_8,Which of the following options best describe the cover story?,"In this May issue...1048Technology is here to stay, and for those early adopters, you're likely reaping the rewards. For those unwilling or unable, this issue's cover feature digs into what's around the corner in the hope of trickledown technology1049Cover illustration by Tim Marrs",D,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/35_8.png,vitg,35_8.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_2.png,vith,37_2.txt,MAC_Bench/Nature/Cover/BDJ In Practice/36_9.png,MAC_Bench/Nature/Cover/BDJ In Practice/36_9.png,clip,36_9.txt,MAC_Bench/Nature/Cover/BDJ In Practice/37_8.png,MAC_Bench/Nature/Cover/BDJ In Practice/37_8.png,groundtruth,37_8.txt,train1050NATURE REVIEWS CANCER,24_2,Which of the following options best describe the cover story?,"Forces that squeeze, inspired by the Review on p768.1051Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_2.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_2.png,groundtruth,24_2.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/17_7.png,vith,17_7.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png,clip,24_6.txt,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_3.png,MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/23_3.png,vitg,23_3.txt,val1052Nature Human Behaviour,8_8,Which of the following options best describe the cover story?,"Chimpanzee social learning1053Is know-how copying a uniquely human capacity? Van Leeuwen and colleagues demonstrate that chimpanzees use social learning to acquire a skill that they failed to innovate, which suggests that chimpanzees — like humans — use know-how copying to expand their skill set.1054See Van Leeuwen et al.1055Image: Chimfunshi Wildlife Orphanage and Clara Dubois. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/4_4.png,clip,4_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_2.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_2.png,ave_3,5_2.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/5_4.png,ave_2,5_4.txt,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_8.png,MAC_Bench/Nature/Cover/Nature Human Behaviour/8_8.png,groundtruth,8_8.txt,train1056NATURE MATERIALS,23_10,Which of the following options best describe the cover story?,"Growing tunable moirés1057Two-dimensional structures with tunable moiré patterns, which display tunable interlayer excitons and moiré intralayer excitons, are achieved by epitaxial bottom-up growth.1058See Fortin-Deschênes et al.1059Image: Yihao Song and Matthieu Fortin-Deschênes, Yale University. Cover design: Alex Whitworth",A,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_10.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/23_10.png,groundtruth,23_10.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_5.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/20_5.png,vith,20_5.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_3.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/21_3.png,clip,21_3.txt,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,MAC_Bench/Nature/Cover/NATURE MATERIALS/22_2.png,vitg,22_2.txt,train1060Cell Reports Physical Science,5_10,Which of the following options best describe the cover story?,"On the cover: Xie et al. report their investigation of the oxidative Nazarov reaction and its application1061to the collective synthesis of five fusicoccane diterpenoids. To celebrate the Chinese1062New Year, a traditional Chinese-style illustration named “Two Loongs Playing with1063a Pearl” is presented to indicate that the oxidative Nazarov reaction is a robust1064synthetic method and a valuable tool for natural product synthesis. Image by Yan Qiu.",D,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/2_9.png,vitg,2_9.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/3_3.png,clip,3_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_3.png,vith,5_3.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_10.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_10.png,groundtruth,5_10.txt,train1065Nature Astronomy,8_3,Which of the following options best describe the cover story?,"Decoding a galaxy’s past with AI1066Constraining the intrinsic and extrinsic stellar mass in a galaxy unlocks its merger history. Here, using the power of artificial intelligence, the authors do this for 10,000 galaxies, finding traits that can be used to characterize even larger samples.1067See Angeloudi et al.1068Image: Gabriel Pérez Díaz (Instituto de Astrofísica de Canarias), image background: NASA/ESA/STScI. Cover design: Bethany Vukomanovic",D,MAC_Bench/Nature/Cover/Nature Astronomy/7_12.png,MAC_Bench/Nature/Cover/Nature Astronomy/7_12.png,ave_2,7_12.txt,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/2_1.png,clip,2_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_1.png,vitg,8_1.txt,MAC_Bench/Nature/Cover/Nature Astronomy/8_3.png,MAC_Bench/Nature/Cover/Nature Astronomy/8_3.png,groundtruth,8_3.txt,test1069ACS Applied Nano Materials,2025_7,Which of the following options best describe the cover story?,"Gold nanoclusters embedded in cross-linked lysozyme crystals exhibit enzyme activity that depends on available diffusion channels and solvent accessibility. When the morphology allows efficient diffusion, gold nanoclusters with lysozyme can serve as tandem catalysts, functioning as both peroxidase and hydrolytic enzymes, showcasing their potential in diverse catalytic applications.",B,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2019_7.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2019_7.png,vitg,2019_7.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_7.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2025_7.png,groundtruth,2025_7.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_5.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2020_5.png,clip,2020_5.txt,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_23.png,MAC_Bench/ACS/Cover/ACS Applied Nano Materials/2023_23.png,ave_3,2023_23.txt,train1070Current Biology,34_21,Which of the following options best describe the cover story?,"On the cover: How does a single cell control its behavior? This is Euplotes, a unicellular organism with a highly complex morphology. The thick bundles of cilia1071called cirri (seen here on the cover) emanating from its lower surface are used for1072walking and swimming. In this issue, Laeverenz-Schlogelhofer and Wan demonstrate the bioelectrical basis for gait control in this walking single cell.1073Simultaneous electrophysiological recordings and high-speed imaging reveal that membrane1074potential regulates cirri activity, enabling Euplotes to rapidly switch between forward walking and turning. Depolarization events orchestrate1075the cell's highly coordinated turning maneuver, with distinct cirri behaving differently.1076SEM micrograph by Christian Hacker; used with permission.",C,MAC_Bench/Cell/Cover/Current Biology/27_17.png,MAC_Bench/Cell/Cover/Current Biology/27_17.png,vitg,27_17.txt,MAC_Bench/Cell/Cover/Current Biology/20_16.png,MAC_Bench/Cell/Cover/Current Biology/20_16.png,vith,20_16.txt,MAC_Bench/Cell/Cover/Current Biology/34_21.png,MAC_Bench/Cell/Cover/Current Biology/34_21.png,groundtruth,34_21.txt,MAC_Bench/Cell/Cover/Current Biology/31_2.png,MAC_Bench/Cell/Cover/Current Biology/31_2.png,clip,31_2.txt,train1077Science Robotics,9_97,Which of the following options best describe the cover story?,"ONLINE COVER Artificial Intelligence—Solving Decision-Making Problems in Dynamical Systems. Autonomous robots need the ability to adaptively make decisions in unstructured and dynamic environments. Rivière et al. have now developed Spectral Expansion Tree Search, a real-time space planning algorithm that can construct representations of the real world and converge to optimal solutions, enabling autonomous robot decision-making in complex environments. They demonstrated the ability of their framework experimentally with aerial and ground robots with the potential to discover optimal trajectories in complex environments. This month’s cover is an image of a robot mimicking a spacecraft deployed with their framework in a simulated frictionless environment. Credit: Vicki Chiu",C,MAC_Bench/Science/Cover/Science Robotics/4_30.png,MAC_Bench/Science/Cover/Science Robotics/4_30.png,vitg,4_30.txt,MAC_Bench/Science/Cover/Science Robotics/8_78.png,MAC_Bench/Science/Cover/Science Robotics/8_78.png,vith,8_78.txt,MAC_Bench/Science/Cover/Science Robotics/9_97.png,MAC_Bench/Science/Cover/Science Robotics/9_97.png,groundtruth,9_97.txt,MAC_Bench/Science/Cover/Science Robotics/6_61.png,MAC_Bench/Science/Cover/Science Robotics/6_61.png,clip,6_61.txt,train1078Nature Chemical Biology,20_4,Which of the following options best describe the cover story?,"Specificity for cathepsin S1079The structure of non-natural peptide inhibitors can be rapidly optimized to specifically block the activity of protease targets. The cover image depicts different non-natural peptides bound to the molecular structure of cathepsin S, representing a few possible outcomes of site saturation mutagenesis screening.1080See Petruzzella et al.1081Image: Aaron Petruzzella, EPFL. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_5.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/19_5.png,clip,19_5.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_10.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/18_10.png,vith,18_10.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_4.png,MAC_Bench/Nature/Cover/Nature Chemical Biology/15_4.png,vitg,15_4.txt,train1082Journal of the American Chemical Society,2024_45,Which of the following options best describe the cover story?,"Lasso peptides are a promising scaffold for small therapeutics with thermal and proteolytic stability. Simulations reveal that de novo folding is possible and can be stabilized through sequence and chemical modifications, opening the door to the chemical synthesis of lasso structures.",B,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_36.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_36.png,vith,2009_36.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_45.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_45.png,groundtruth,2024_45.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2018_4.png,vitg,2018_4.txt,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_19.png,MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2009_19.png,clip,2009_19.txt,train1083Nature Cardiovascular Research,3_10,Which of the following options best describe the cover story?,"Neutralizing gremlins protects against myocarditis1084Perez-Shibayama et al. report that restoring BMP4 signaling with antibodies that neutralize the BMP inhibitors gremlin-1 and gremlin-2 can ameliorate myocarditis by reducing immune cell infiltration, the production of pathogenic cytokines, and pro-inflammatory activity in fibroblasts.1085See Perez-Shibayama et al.1086Image: Nadine Cadosch, Kantonsspital St. Gallen, St. Gallen, Switzerland. Cover design: Bethany Vukomanovic.",D,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_11.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/1_11.png,clip,1_11.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_10.png,vith,2_10.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/2_5.png,vitg,2_5.txt,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_10.png,MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_10.png,groundtruth,3_10.txt,train1087Science Translational Medicine,17_785,Which of the following options best describe the cover story?,"ONLINE COVER Expanding Liver Gene Editing. The cover shows gene-targeted and expanded adult mouse hepatocytes (red) and a counterstain for DNA (blue). Homology-directed repair (HDR)-based techniques show promise for gene editing of liver diseases, but they do not always achieve sufficient editing of adult cells. To improve HDR-based hepatocyte editing, De Giorgi et al. created a system that conditions the liver by transiently knocking down the essential gene fumarylacetoacetate hydrolase (Fah), and then inserts a therapeutic transgene of choice alongside a non-targetable version of Fah into the highly expressed Apolipoprotein A1 (Apoa1) locus, to protect the hepatocytes from further injury. A high-protein diet in these mice increased expansion of edited hepatocytes and corrected of about a quarter of all hepatocytes in the liver, and increased the expression of therapeutic transgene human factor IX (FIX) by five-fold. This increased expansion of targeted hepatocytes may expand the number of liver diseases targetable by gene therapy. Credit: Marco De Giorgi",B,MAC_Bench/Science/Cover/Science Translational Medicine/15_715.png,MAC_Bench/Science/Cover/Science Translational Medicine/15_715.png,clip,15_715.txt,MAC_Bench/Science/Cover/Science Translational Medicine/17_785.png,MAC_Bench/Science/Cover/Science Translational Medicine/17_785.png,groundtruth,17_785.txt,MAC_Bench/Science/Cover/Science Translational Medicine/13_601.png,MAC_Bench/Science/Cover/Science Translational Medicine/13_601.png,ave_0,13_601.txt,MAC_Bench/Science/Cover/Science Translational Medicine/5_174.png,MAC_Bench/Science/Cover/Science Translational Medicine/5_174.png,vitg,5_174.txt,train1088ACS Earth and Space Chemistry,2024_7,Which of the following options best describe the cover story?,A range of cationic hydroxylated silicon oxide species are produced and their infrared (IR) spectra are,A,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_7.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_8.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2023_8.png,ave_1,2023_8.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2022_4.png,vitg,2022_4.txt,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,MAC_Bench/ACS/Cover/ACS Earth and Space Chemistry/2024_1.png,clip,2024_1.txt,train1089Cancer Cell,42_6,Which of the following options best describe the cover story?,"On the cover: Casanova-Salas et al. demonstrate how the genomic and transcriptomic cargo within circulating extracellular1090vesicles (EVs) from liquid biopsies provides valuable insights into metastatic prostate1091cancer outcomes and treatment responses and how this information could facilitate1092the identification of biomarkers for guiding therapy switch decisions. The cover artwork1093features an EV-lit traffic light, symbolizing the important role that circulating1094EVs could play in the trafficking of clinically actionable information. Image credit:1095Carlos Córdoba Terreros.",B,MAC_Bench/Cell/Cover/Cancer Cell/37_5.png,MAC_Bench/Cell/Cover/Cancer Cell/37_5.png,clip,37_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/42_6.png,MAC_Bench/Cell/Cover/Cancer Cell/42_6.png,groundtruth,42_6.txt,MAC_Bench/Cell/Cover/Cancer Cell/16_5.png,MAC_Bench/Cell/Cover/Cancer Cell/16_5.png,vitg,16_5.txt,MAC_Bench/Cell/Cover/Cancer Cell/34_2.png,MAC_Bench/Cell/Cover/Cancer Cell/34_2.png,vith,34_2.txt,train1096Nature Reviews Nephrology,20_2,Which of the following options best describe the cover story?,"Drug repurposing, inspired by the Review on p707.1097Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_2.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_2.png,groundtruth,20_2.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,clip,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_5.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/18_5.png,vitg,18_5.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_8.png,vith,17_8.txt,val1098Cell Metabolism,36_5,Which of the following options best describe the cover story?,"On the cover: Th17 cells are essential for protecting the gut from infections and1099maintaining mucosal immunity. Bonetti et al. demonstrate that glutathione (GSH)-mediated control of mitochondrial reactive oxygen1100species (mROS) is critical for Th17 cell function. Accumulation of ROS in Th17 cells1101disrupts mitochondrial transcription and energy production, which is linked to the1102translation of IL-22. Unlike IL-17, GSH-regulated IL-22 prevents the spread of bacteria1103to peripheral organs. On the cover, the complex interplay between GSH and ROS in Th171104cells within the intestine is depicted as a crossword puzzle. While IL-17 initially1105appears to be the correct answer, it is crossed out and replaced by IL-22, which is1106important for the maintenance of functional intestinal homeostasis. Picture by Lynn1107Bonetti.",B,MAC_Bench/Cell/Cover/Cell Metabolism/15_4.png,MAC_Bench/Cell/Cover/Cell Metabolism/15_4.png,vitg,15_4.txt,MAC_Bench/Cell/Cover/Cell Metabolism/36_5.png,MAC_Bench/Cell/Cover/Cell Metabolism/36_5.png,groundtruth,36_5.txt,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,MAC_Bench/Cell/Cover/Cell Metabolism/12_3.png,vith,12_3.txt,MAC_Bench/Cell/Cover/Cell Metabolism/17_1.png,MAC_Bench/Cell/Cover/Cell Metabolism/17_1.png,clip,17_1.txt,test1108Nature Reviews Nephrology,20_1,Which of the following options best describe the cover story?,"Amino acid metabolism, inspired by the Review on p771.1109Cover design: Lara Crow",A,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_1.png,groundtruth,20_1.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_3.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_3.png,ave_3,17_3.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_6.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/19_6.png,clip,19_6.txt,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,MAC_Bench/Nature/Cover/Nature Reviews Nephrology/17_10.png,vith,17_10.txt,train1110Molecular Therapy,32_15,Which of the following options best describe the cover story?,"On the cover: Pyroptosis is an inflammatory form of programmed cell death that occurs upon infection.1111Kou and colleagues revealed that pyroptotic cells generate a new group of pyroptotic extracellular vesicles1112(pyroEVs) and uncover the therapeutic effect of mesenchymal stem cell-derived pyroEVs1113on sepsis. Specific expressed ASC can serve as a functional marker identifying exogenous1114and endogenous pyroEVs and mediating the protective effect of pyroEV on B cells. In1115this image, even the “fiery falling” pyroptotic cells will generate small nutrient1116vesicles to protect the damaged host B cells during infection, thus rescuing sepsis.1117Image credit: Suqian Qinyan Information Technology Co., LTD.",B,MAC_Bench/Cell/Cover/Molecular Therapy/25_5.png,MAC_Bench/Cell/Cover/Molecular Therapy/25_5.png,clip,25_5.txt,MAC_Bench/Cell/Cover/Molecular Therapy/32_15.png,MAC_Bench/Cell/Cover/Molecular Therapy/32_15.png,groundtruth,32_15.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_3.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_3.png,vith,31_3.txt,MAC_Bench/Cell/Cover/Molecular Therapy/31_8.png,MAC_Bench/Cell/Cover/Molecular Therapy/31_8.png,vitg,31_8.txt,train1118ACS Catalysis,2024_20,Which of the following options best describe the cover story?,"Pulsed-laser decoration of single Pd nanoparticles on NiCo2O4 nanoplates resulted in a Pd/NiCo2O4 composite with excellent bifunctional electrocatalytic activity in both the hydrogen evolution reaction and the hydrazine oxidation reaction. Accordingly, the assembled hybrid electrolyzer achieves low-voltage-driven hydrogen production while simultaneously degrading hydrazine in wastewater into nitrogen, effectively achieving dual objectives with a single strategy.",D,MAC_Bench/ACS/Cover/ACS Catalysis/2017_10.png,MAC_Bench/ACS/Cover/ACS Catalysis/2017_10.png,vitg,2017_10.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_11.png,clip,2024_11.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2023_1.png,MAC_Bench/ACS/Cover/ACS Catalysis/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/ACS Catalysis/2024_20.png,MAC_Bench/ACS/Cover/ACS Catalysis/2024_20.png,groundtruth,2024_20.txt,val1119Cell Reports Physical Science,6_2,Which of the following options best describe the cover story?,"On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December11202024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for1121his help in creating this beautiful cover.",A,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_2.png,groundtruth,6_2.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_2.png,clip,5_2.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_6.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/4_6.png,ave_0,4_6.txt,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_1.png,MAC_Bench/Cell/Cover/Cell Reports Physical Science/6_1.png,vitg,6_1.txt,train1122ACS Agricultural Science & Technology,2024_2,Which of the following options best describe the cover story?,"The image shows Khasi mandarin oranges inside a container, connected to sensors measuring their ripeness and respiration rate. This study uses AI to predict how long the fruit will stay fresh, helping to make better decisions for storage, pricing, and reducing waste.",D,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_6.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2022_6.png,vitg,2022_6.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2021_6.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2021_6.png,clip,2021_6.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_2.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2023_2.png,vith,2023_2.txt,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_2.png,MAC_Bench/ACS/Cover/ACS Agricultural Science & Technology/2024_2.png,groundtruth,2024_2.txt,train1123Nature Geoscience,18_1,Which of the following options best describe the cover story?,"High mountain hazard cascade1124Perched at 3,600 m elevation in the Himalayan mountains of Nepal, massive glacial sediment deposits were incised by nearly 100 m in a geological instant during monsoonal flooding in 2021. The sediment unleashed by this event set in motion an erosional chain reaction with devastating consequences downstream, exemplifying the cascading hazard posed by sediment-laden floods in high mountains.1125See Chen et al.1126Image: Chan-Mao Chen, University of Southern California. Cover design: Alex Wing",D,MAC_Bench/Nature/Cover/Nature Geoscience/6_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_12.png,clip,6_12.txt,MAC_Bench/Nature/Cover/Nature Geoscience/15_6.png,MAC_Bench/Nature/Cover/Nature Geoscience/15_6.png,ave_3,15_6.txt,MAC_Bench/Nature/Cover/Nature Geoscience/14_12.png,MAC_Bench/Nature/Cover/Nature Geoscience/14_12.png,ave_2,14_12.txt,MAC_Bench/Nature/Cover/Nature Geoscience/18_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/18_1.png,groundtruth,18_1.txt,train1127Nature Mental Health,2_11,Which of the following options best describe the cover story?,"Climate mental health1128The February cover is a moody depiction of climate mental health. Intended to invoke the idea of the interplay among Gaia (the spirit of Earth), nature and humanity, the blue tones also reference the Connecting Climate Minds project. As a means for placing mental health prominently in climate agendas, this initiative is a catalyst for invigorating the broader climate mental health field.1129See our Editorial for more on the emerging field of climate mental health1130Image: Rebeka Ryvola/Climate Cares Centre. Cover design: Debbie Maizels",B,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_3.png,clip,2_3.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_11.png,groundtruth,2_11.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png,ave_2,2_5.txt,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,MAC_Bench/Nature/Cover/Nature Mental Health/2_6.png,vitg,2_6.txt,train1131Nature Reviews Rheumatology,20_4,Which of the following options best describe the cover story?,"Inspired by the Review on p531.1132Cover design: Steven Hall",B,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_11.png,vitg,19_11.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_4.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_4.png,groundtruth,20_4.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/11_12.png,vith,11_12.txt,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/19_12.png,clip,19_12.txt,train1133Cell Stem Cell,31_4,Which of the following options best describe the cover story?,"On the cover: In some mammalian species, the blastocyst-stage embryo suspends its1134development and enters a state of “deep sleep” (embryo dormancy or diapause). The1135cover image depicts a dreamcatcher with an integrated embryo pattern in the center1136to symbolize this peculiar state. In addition to dormancy, the round shape of the1137dreamcatcher symbolizes the maternal environment (uterine tube) illustrating that1138an analysis of this state by Chen et al. has been performed in physiological conditions. Moreover, the interconnected nodes1139in the dreamcatcher symbolize the gene networks identified by single-cell sequencing.1140Image courtesy of the authors.",B,MAC_Bench/Cell/Cover/Cell Stem Cell/6_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/6_2.png,vitg,6_2.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/31_4.png,MAC_Bench/Cell/Cover/Cell Stem Cell/31_4.png,groundtruth,31_4.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/29_3.png,MAC_Bench/Cell/Cover/Cell Stem Cell/29_3.png,clip,29_3.txt,MAC_Bench/Cell/Cover/Cell Stem Cell/12_2.png,MAC_Bench/Cell/Cover/Cell Stem Cell/12_2.png,ave_2,12_2.txt,test1141ACS Central Science,2024_7,Which of the following options best describe the cover story?,"Shown in cartoon form is the key finding described by Yang et al., namely, that electron transfer between two pyrrole-based macrocycles and iodine can be readily controlled through the judicious choice of small molecule “players” and variations in the concentration. This work advances our understanding of fundamentals relevant to energy, catalysis, and molecular electronics.",A,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_7.png,groundtruth,2024_7.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_2.png,vith,2024_2.txt,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,MAC_Bench/ACS/Cover/ACS Central Science/2024_9.png,vitg,2024_9.txt,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,MAC_Bench/ACS/Cover/ACS Central Science/2025_2.png,clip,2025_2.txt,train1142Macromolecules,2024_17,Which of the following options best describe the cover story?,Bottlebrush polymers with helical and nonhelical sidechains (tuned by the monomer chirality) impact the backbone breadth in solution and the rate of mechanochemistry. View the article.,B,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,MAC_Bench/ACS/Cover/Macromolecules/2012_5.png,clip,2012_5.txt,MAC_Bench/ACS/Cover/Macromolecules/2024_17.png,MAC_Bench/ACS/Cover/Macromolecules/2024_17.png,groundtruth,2024_17.txt,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,MAC_Bench/ACS/Cover/Macromolecules/2022_18.png,vith,2022_18.txt,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,MAC_Bench/ACS/Cover/Macromolecules/2014_20.png,vitg,2014_20.txt,test1143Cell Systems,15_11,Which of the following options best describe the cover story?,"On the cover: Lung cancer cells expressing the CluMPS reporter (magenta) show large1144puncta that indicate the presence of small, hard-to-see clusters of its target (EML4-ALK,1145green). In this issue of Cell Systems, Mumford et al. introduce CluMPS (clusters magnified by phase separation), a fluorescent reporter1146for detecting small protein clusters in living cells. The combined multivalency of1147CluMPS and a multimerized target produces large condensates that are detectable with1148standard microscopy. CluMPS can detect and track clusters of both endogenous and exogenous1149proteins. Image credit: Thomas Mumford.",A,MAC_Bench/Cell/Cover/Cell Systems/15_11.png,MAC_Bench/Cell/Cover/Cell Systems/15_11.png,groundtruth,15_11.txt,MAC_Bench/Cell/Cover/Cell Systems/5_4.png,MAC_Bench/Cell/Cover/Cell Systems/5_4.png,clip,5_4.txt,MAC_Bench/Cell/Cover/Cell Systems/13_3.png,MAC_Bench/Cell/Cover/Cell Systems/13_3.png,vith,13_3.txt,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,MAC_Bench/Cell/Cover/Cell Systems/1_2.png,vitg,1_2.txt,test1150Med,5_7,Which of the following options best describe the cover story?,"On the cover: This issue of Med explores the applications of CAR T cell therapies beyond hematologic malignancies,1151including solid tumors and autoimmune diseases. A Q&A with Fabian Müller (University Hospital Erlangen) covers the latest developments in the field. A Review1152from Liu et al. discusses emerging combination strategies using CAR T cells in solid tumors, while1153Shu et al. review the exciting potential of CAR technology in non-neoplastic diseases. Fischbach et al. present a Case Report describing the safety and feasibility of CD19-targeted CAR1154T-cell therapy in the first two patients with progressive multiple sclerosis, with1155an accompanying Viewpoint from Rankin and Shah highlighting the new frontiers of CAR T cell therapies. Cover credit: Keith Chambers/Science1156Photo Library via Getty Images.",C,MAC_Bench/Cell/Cover/Med/4_6.png,MAC_Bench/Cell/Cover/Med/4_6.png,vith,4_6.txt,MAC_Bench/Cell/Cover/Med/2_4.png,MAC_Bench/Cell/Cover/Med/2_4.png,vitg,2_4.txt,MAC_Bench/Cell/Cover/Med/5_7.png,MAC_Bench/Cell/Cover/Med/5_7.png,groundtruth,5_7.txt,MAC_Bench/Cell/Cover/Med/5_9.png,MAC_Bench/Cell/Cover/Med/5_9.png,clip,5_9.txt,train1157Trends in Chemistry,6_1,Which of the following options best describe the cover story?,"All materials contain defects that can change their stability, characteristics1158and behaviour. Computational simulations of these defects can help scientists to more1159accurately predict their occurrence, concentration and resultant chemical properties.1160In1161their Forum article in this issue, Gormley and Hendon examine the nuances of calculating1162defect formation energetics in molecular materials, with a focus on highlighting some1163of the strategies theorists can use specifically to treat the chemical potential and1164correctional terms of the calculation. Better predictions can help make these calculations1165a crucial tool in the design and understanding of new materials. Cover image credit:1166GettyImages/Tom Gowanlock",B,MAC_Bench/Cell/Cover/Trends in Chemistry/4_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/4_1.png,vith,4_1.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/6_1.png,MAC_Bench/Cell/Cover/Trends in Chemistry/6_1.png,groundtruth,6_1.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/3_8.png,MAC_Bench/Cell/Cover/Trends in Chemistry/3_8.png,vitg,3_8.txt,MAC_Bench/Cell/Cover/Trends in Chemistry/2_10.png,MAC_Bench/Cell/Cover/Trends in Chemistry/2_10.png,clip,2_10.txt,train1167ACS Sustainable Chemistry & Engineering,2025_2,Which of the following options best describe the cover story?,Self-assembly of cellulose nanocrystals (CNCs) synthesized from rice straw yields transparent films with distinct structural colors. Amine modification of CNCs significantly improves the electron mobility and current–voltage characteristics. The transreflective property and photoresponsivity of,D,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_47.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2021_47.png,vitg,2021_47.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_3.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_3.png,vith,2015_3.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_7.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2015_7.png,clip,2015_7.txt,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_2.png,MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_2.png,groundtruth,2025_2.txt,test1168Analytical Chemistry,2025_2,Which of the following options best describe the cover story?,"3D-printed dual-channel flow-through miniaturized devices (3Dd) with dual electrochemical detection (EDd) integrating two working electrodes each in an in-channel configuration (3Dd–EDd), are combined with the rich PB-based electrochemistry to obtain reliable, stable, and ready-to-use devices with excellent analytical performance toward hydrogen peroxide detection in cultivar cells.",D,MAC_Bench/ACS/Cover/Analytical Chemistry/2021_37.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2021_37.png,clip,2021_37.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2016_5.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2016_5.png,vith,2016_5.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2014_16.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2014_16.png,vitg,2014_16.txt,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_2.png,MAC_Bench/ACS/Cover/Analytical Chemistry/2025_2.png,groundtruth,2025_2.txt,test1169The Journal of Physical Chemistry Letters,2025_1,Which of the following options best describe the cover story?,"This visualization highlights the integration of artificial intelligence (AI) in analyzing X-ray diffraction (XRD) patterns for advanced material characterization. The image depicts AI-assisted processing of diffraction data, where machine-learning models facilitate full atomic structure characterization from experimental observations.",A,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_1.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2025_1.png,groundtruth,2025_1.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2022_30.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2022_30.png,vitg,2022_30.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_43.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2021_43.png,vith,2021_43.txt,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2011_3.png,MAC_Bench/ACS/Cover/The Journal of Physical Chemistry Letters/2011_3.png,clip,2011_3.txt,train1170Evidence-Based Dentistry,25_3,Which of the following options best describe the cover story?,"In this issue:1171This issue evaluates the evidence of effectiveness of some of the major dental public health initiatives and policy decisions. It also explores whether new approaches to prevention and treatment might prove effective against the most common dental diseases.1172Cover illustration by Gary Neill",A,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_3.png,groundtruth,25_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_3.png,vitg,24_3.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/24_4.png,clip,24_4.txt,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,MAC_Bench/Nature/Cover/Evidence-Based Dentistry/25_4.png,ave_2,25_4.txt,test1173Nature Biomedical Engineering,8_2,Which of the following options best describe the cover story?,"Biomolecular condensates as intracellular drug reservoirs1174This issue highlights histopathological biomarkers for predicting the tumour accumulation of nanomedicines, the profiling of protein–protein interactions to predict the efficacy of inhibitors of acute myeloid leukaemia, the intravenous injection of oxygen via polymeric microbubbles for the treatment of hypoxaemia, the structural optimization of ionizable lipids in nanoparticles to improve their delivery activity and biodegradability, the radiation-induced reduction of platinum prodrugs, exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases, antibody-displaying extracellular vesicles for cancer therapy, the controlled formation of biomolecular condensates as intracellular drug reservoirs, and how amine headgroups in ionizable lipids drive the immunogenicity of lipid nanoparticles.1175The cover illustrates a method for forming biomolecular condensates that serve as drug reservoirs within cancer cells.1176See Liang et al.1177Image: Zhen Gu, Hongjun Li and Tingxizi Liang, Zhejiang University. Cover design: Alex Wing.",C,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/4_12.png,ave_1,4_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_12.png,clip,7_12.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_2.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_2.png,groundtruth,8_2.txt,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,MAC_Bench/Nature/Cover/Nature Biomedical Engineering/7_4.png,vith,7_4.txt,test1178Nature Geoscience,17_3,Which of the following options best describe the cover story?,"Graphitic carbon cycling during mountain building1179Coupled rhenium–osmium and uranium–lead dating suggest graphitic carbon was hydrothermally cycled through shear zones during late-stage orogenesis associated with Nuna supercontinent assembly. The photomicrograph shows a hydrothermal graphite–pyrite vein in a highly sheared, metasomatized metapelite host rock viewed under both reflected and transmitted light (image dimensions: 550 μm x 550 μm). Graphite stands out from the ground mass due to its brown colour, high reflectance, and platy crystal habit.1180See Toma et al.1181Image: Jonathan Toma. Cover design: Alex Wing",C,MAC_Bench/Nature/Cover/Nature Geoscience/2_5.png,MAC_Bench/Nature/Cover/Nature Geoscience/2_5.png,vith,2_5.txt,MAC_Bench/Nature/Cover/Nature Geoscience/6_7.png,MAC_Bench/Nature/Cover/Nature Geoscience/6_7.png,vitg,6_7.txt,MAC_Bench/Nature/Cover/Nature Geoscience/17_3.png,MAC_Bench/Nature/Cover/Nature Geoscience/17_3.png,groundtruth,17_3.txt,MAC_Bench/Nature/Cover/Nature Geoscience/12_1.png,MAC_Bench/Nature/Cover/Nature Geoscience/12_1.png,clip,12_1.txt,train1182Chemical Research in Toxicology,2024_5,Which of the following options best describe the cover story?,"Mn(III) chloride (TDCPP) can be used as an abiotic CYP enzyme for the metabolic activation of genotoxic chemicals, such as cyclophosphamide, in in vitro cell-based bioassays as an animal-free alternative to rat liver microsomes or S9 fraction.",C,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_1.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_1.png,vith,2023_1.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2023_8.png,clip,2023_8.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_5.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2024_5.png,groundtruth,2024_5.txt,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2021_4.png,MAC_Bench/ACS/Cover/Chemical Research in Toxicology/2021_4.png,ave_2,2021_4.txt,train1183Nature Food,6_1,Which of the following options best describe the cover story?,"Nature Food 1184Since the publication of Nature Food’s  first issue in January 2020, food systems research has come a long way — and much remains to be done. We celebrate the journal’s anniversary with a Focus issue and a webinar series.1185See Editorial1186Image: Shawn Williams / Alamy Stock Photo. Cover design: Tulsi Voralia",B,MAC_Bench/Nature/Cover/Nature Food/5_2.png,MAC_Bench/Nature/Cover/Nature Food/5_2.png,vitg,5_2.txt,MAC_Bench/Nature/Cover/Nature Food/6_1.png,MAC_Bench/Nature/Cover/Nature Food/6_1.png,groundtruth,6_1.txt,MAC_Bench/Nature/Cover/Nature Food/2_7.png,MAC_Bench/Nature/Cover/Nature Food/2_7.png,vith,2_7.txt,MAC_Bench/Nature/Cover/Nature Food/2_3.png,MAC_Bench/Nature/Cover/Nature Food/2_3.png,clip,2_3.txt,train1187Accounts of Chemical Research,2024_14,Which of the following options best describe the cover story?,"In the past, glycan synthesis has been difficult, requiring multi-step manual operations and a highly skilled workforce (at the remote end). Through the time and space tunnel, a donor preactivation-based strategy has enabled glycan synthesis from oligosaccharides to polysaccharides and from manual to automated synthesis, reaching a new height (at the proximal end).",A,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_14.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_14.png,groundtruth,2024_14.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_4.png,ave_1,2020_4.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2017_9.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2017_9.png,clip,2017_9.txt,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_3.png,MAC_Bench/ACS/Cover/Accounts of Chemical Research/2020_3.png,ave_2,2020_3.txt,train1188ACS Measurement Science Au,2022_3,Which of the following options best describe the cover story?,Seeing is not believing: The weak transient current signals of single-particle collisions we recorded are often distorted by amplifiers' filter and the noise. It seems like we “see” signals from the reflection in the water. The “ripples” and “waving shadow” mask our “believing” of the dynamic nature of individual entities.,C,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2025_1.png,clip,2025_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2021_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2021_1.png,ave_2,2021_1.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_3.png,groundtruth,2022_3.txt,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_1.png,vitg,2022_1.txt,train1189Industrial & Engineering Chemistry Research,2024_37,Which of the following options best describe the cover story?,"The high concentration of oxygen vacancies on Ni/CeO2-NS facilitates the activation of water and oxygen molecules during methanol oxidative steam reforming, leading to enhanced conversion of methanol to hydrogen.",B,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2021_45.png,clip,2021_45.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_37.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_37.png,groundtruth,2024_37.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_16.png,vitg,2024_16.txt,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png,vith,2024_36.txt,val1190Med,5_6,Which of the following options best describe the cover story?,"On the cover: Chemotherapies are currently dosed based on a patient's height and weight,1191using an equation from 1916 to estimate their body surface area. This method leads1192to variability in pharmacokinetics, potentially causing increased toxicities and decreased1193efficacy. Personalized dosing could improve the patient's experience by providing1194a more accurate dose, reducing side effects and increasing drug efficacy. In this1195issue of Med, DeRidder et al. develop a closed-loop automated drug infusion regulator (CLAUDIA) system to address1196this challenge by ensuring the drug reaches the target concentration regardless of1197other factors. This illustration depicts a positive treatment experience, with patients1198walking unbothered by their personalized chemotherapy dose represented by colorful1199IV bags floating like balloons. Recovery is gentler, and daily life is less impacted1200by chemotherapy. Cover credit: Virginia E. Fulford.",B,MAC_Bench/Cell/Cover/Med/2_4.png,MAC_Bench/Cell/Cover/Med/2_4.png,clip,2_4.txt,MAC_Bench/Cell/Cover/Med/5_6.png,MAC_Bench/Cell/Cover/Med/5_6.png,groundtruth,5_6.txt,MAC_Bench/Cell/Cover/Med/6_1.png,MAC_Bench/Cell/Cover/Med/6_1.png,ave_3,6_1.txt,MAC_Bench/Cell/Cover/Med/3_1.png,MAC_Bench/Cell/Cover/Med/3_1.png,ave_2,3_1.txt,train

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