guohanghui/SPM

1### SPM2### Introduction3This python script of Sequence Pattern Matching (SPM) alignment was written by WuLab & YanLab, School of Life Sciences, Westlake University.4 5It can help you search target proteins against a cryo-EM map from a given sequence database. 6 7Inputs are a query peptide sequence and a protein database for searching. Output is a ranking protein list, each with a score and best matching postion. The most possible candidate is at the top of the output file.8 9### Usage10 11# 1. Clone this repository into local12 13```bash14git clone https://github.com/YanLab-Westlake/SPM.git15```16 17# 2. Running the test example (optional)18```bash19cd SPM20bash tests/SPM_test.sh21```22 23# 3. Running the search with your own data24```bash25python scripts/SequencePatternMatching.py -q {One-Letter-Sequence} -d {Search-Sequence-Library} -o {Output_name}26```27 28### Cite us29If you use this script, please cite the following paper:30Jin et al., Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes, Cell (2022), https://doi.org/10.1016/j.cell.2022.10.03031 32